GO term | GO name | GO namespace | GO def |
GO:0004197 | cysteine-type endopeptidase activity | molecular_function | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE] |
GO:0008152 | metabolic process | biological_process | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [GOC:go_curators, ISBN:0198547684] |
GO:0043170 | macromolecule metabolic process | biological_process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:mah] |
GO:0044237 | cellular metabolic process | biological_process | The chemical reactions and pathways by which individual cells transform chemical substances. [GOC:go_curators] |
GO:0016853 | isomerase activity | molecular_function | Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. [ISBN:0198506732] |
GO:1902494 | catalytic complex | cellular_component | A protein complex which is capable of catalytic activity. [GOC:bhm, GOC:TermGenie, PMID:8077207] |
GO:0044238 | primary metabolic process | biological_process | The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [GOC:go_curators, http://www.metacyc.org] |
GO:0019538 | protein metabolic process | biological_process | The chemical reactions and pathways involving a protein. Includes protein modification. [GOC:ma] |
GO:0035091 | phosphatidylinositol binding | molecular_function | Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. [GOC:bf, ISBN:0198506732, PMID:11395417] |
GO:0097367 | carbohydrate derivative binding | molecular_function | Binding to a carbohydrate derivative. [GOC:pr] |
GO:0098796 | membrane protein complex | cellular_component | Any protein complex that is part of a membrane. [GOC:dos] |
GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
GO:0071704 | organic substance metabolic process | biological_process | The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. [GOC:mah] |
GO:0034394 | protein localization to cell surface | biological_process | A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. [GOC:mah] |
GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |
GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |
GO:0036211 | protein modification process | biological_process | The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:bf, GOC:jl] |
GO:0003824 | catalytic activity | molecular_function | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732] |
GO:0140096 | catalytic activity, acting on a protein | molecular_function | Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt] |
GO:0044260 | cellular macromolecule metabolic process | biological_process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. [GOC:mah] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0008233 | peptidase activity | molecular_function | Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. [GOC:jl, ISBN:0815332181] |
GO:0006508 | proteolysis | biological_process | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah] |
GO:0005543 | phospholipid binding | molecular_function | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. [ISBN:0198506732] |
GO:0016787 | hydrolase activity | molecular_function | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [ISBN:0198506732] |
GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
GO:1901564 | organonitrogen compound metabolic process | biological_process | The chemical reactions and pathways involving organonitrogen compound. [GOC:pr, GOC:TermGenie] |
GO:0004175 | endopeptidase activity | molecular_function | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. [http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] |
GO:0008234 | cysteine-type peptidase activity | molecular_function | Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE] |
GO:1905369 | endopeptidase complex | cellular_component | A protein complex which is capable of endopeptidase activity. [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] |
GO:0008289 | lipid binding | molecular_function | Binding to a lipid. [GOC:ai] |
GO:0006807 | nitrogen compound metabolic process | biological_process | The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. [GOC:jl, ISBN:0198506732] |
GO:0006464 | cellular protein modification process | biological_process | The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:go_curators] |
GO:0043412 | macromolecule modification | biological_process | The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. [GOC:go_curators] |
GO:0009987 | cellular process | biological_process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete] |
GO:1905368 | peptidase complex | cellular_component | A protein complex which is capable of peptidase activity. [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] |
GO:0044267 | cellular protein metabolic process | biological_process | The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. [GOC:jl] |