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MIB2_ENST00000504599 ,MIB2 ,Q96AX9
  • Uniprot Accession= Q96AX9
  • Ensembl Transcript= ENST00000504599.5
  • Uniprot Name= MIB2
  • Name= E3 ubiquitin-protein ligase MIB2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 12
GO term
GO name
GO namespace
GO def
GO:0008270 zinc ion binding molecular_function Binding to a zinc ion (Zn). [GOC:ai]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0003779 actin binding molecular_function Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt]
GO:0007219 Notch signaling pathway biological_process A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. [GOC:go_curators, GOC:signaling]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0004842 ubiquitin-protein transferase activity molecular_function Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. [GOC:BioGRID, GOC:jh2, PMID:9635407]
GO:0016567 protein ubiquitination biological_process The process in which one or more ubiquitin groups are added to a protein. [GOC:ai]
GO:0000151 ubiquitin ligase complex cellular_component A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex. [GOC:jh2, PMID:9529603]
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. [GOC:jl]
GO:0005769 early endosome cellular_component A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. [GOC:mah, NIF_Subcellular:nlx_subcell_20090701, PMID:19696797]
GO:0061630 ubiquitin protein ligase activity molecular_function Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]