Total number of protein in "GO:2001251" GO term: 45
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACD_ENST00000620761 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:2001251 | Not Cancer Driver | No | 49 | 0.107 | 256 | 34 | 0.133 | 1 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:2001251 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:2001251 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BAZ1B_ENST00000404251 | BAZ1B | Q9UIG0 | Tyrosine-protein kinase BAZ1B | chr7 | GO:2001251 | Not Cancer Driver | No | 153 | 0.103 | 840 | 87 | 0.104 | 0 |
| CTC1 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:2001251 | Not Cancer Driver | No | 142 | 0.117 | 103 | 8 | 0.078 | 9 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:2001251 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:2001251 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:2001251 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| ESPL1 | ESPL1 | Q14674 | Separin | chr12 | GO:2001251 | Not Cancer Driver | No | 211 | 0.1 | 380 | 39 | 0.103 | 0 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:2001251 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| GNL3L_ENST00000360845 | GNL3L | Q9NVN8 | Guanine nucleotide-binding protein-like 3-like protein | chrX | GO:2001251 | Not Cancer Driver | No | 120 | 0.206 | 242 | 43 | 0.178 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:2001251 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:2001251 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | GO:2001251 | Not Cancer Driver | No | 70 | 0.188 | 290 | 58 | 0.2 | 4 |
| HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | GO:2001251 | Not Cancer Driver | No | 42 | 0.137 | 227 | 35 | 0.154 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:2001251 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
| MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | GO:2001251 | Not Cancer Driver | No | 104 | 0.115 | 275 | 38 | 0.138 | 1 |
| MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:2001251 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
| NAA10 | NAA10 | P41227 | N-alpha-acetyltransferase 10 | chrX | GO:2001251 | Not Cancer Driver | No | 33 | 0.14 | 117 | 17 | 0.145 | 3 |
| NAT10 | NAT10 | Q9H0A0 | RNA cytidine acetyltransferase | chr11 | GO:2001251 | Not Cancer Driver | No | 109 | 0.106 | 142 | 18 | 0.127 | 0 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:2001251 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:2001251 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
| PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:2001251 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
| PINX1 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:2001251 | Not Cancer Driver | No | 66 | 0.201 | 328 | 66 | 0.201 | 0 |
| POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:2001251 | Census, Compendium | Yes | 113 | 0.178 | 31 | 6 | 0.194 | 9 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:2001251 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:2001251 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:2001251 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:2001251 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
| SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:2001251 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
| SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | GO:2001251 | Not Cancer Driver | No | 116 | 0.11 | 363 | 48 | 0.132 | 0 |
| SMG6 | SMG6 | Q86US8 | Telomerase-binding protein EST1A | chr17 | GO:2001251 | Not Cancer Driver | No | 166 | 0.117 | 751 | 97 | 0.129 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:2001251 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| STN1 | STN1 | Q9H668 | CST complex subunit STN1 | chr10 | GO:2001251 | Not Cancer Driver | No | 41 | 0.111 | 27 | 2 | 0.074 | 2 |
| TEN1 | TEN1 | Q86WV5 | CST complex subunit TEN1 | chr17 | GO:2001251 | Not Cancer Driver | No | 6 | 0.049 | 8 | 4 | 0.5 | 0 |
| TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:2001251 | Not Cancer Driver | No | 63 | 0.144 | 220 | 34 | 0.155 | 0 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:2001251 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:2001251 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
| TINF2 | TINF2 | Q9BSI4 | TERF1-interacting nuclear factor 2 | chr14 | GO:2001251 | Not Cancer Driver | No | 38 | 0.084 | 190 | 17 | 0.089 | 4 |
| TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:2001251 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
| TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:2001251 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:2001251 | Compendium | Yes | 150 | 0.098 | 508 | 59 | 0.116 | 0 |
| WAPL_ENST00000618527 | WAPL | Q7Z5K2 | Wings apart-like protein homolog | chr10 | GO:2001251 | Not Cancer Driver | No | 140 | 0.118 | 621 | 68 | 0.11 | 0 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:2001251 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:2001251 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |