Total number of protein in "GO:1990204" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BCKDHA | BCKDHA | P12694 | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | chr19 | GO:1990204 | Not Cancer Driver | No | 53 | 0.119 | 121 | 18 | 0.149 | 11 |
| BCKDHB | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | chr6 | GO:1990204 | Not Cancer Driver | No | 47 | 0.12 | 23 | 3 | 0.13 | 5 |
| BCKDK | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | GO:1990204 | Not Cancer Driver | No | 62 | 0.15 | 39 | 3 | 0.077 | 3 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:1990204 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CBR4 | CBR4 | Q8N4T8 | 3-oxoacyl-[acyl-carrier-protein] reductase | chr4 | GO:1990204 | Not Cancer Driver | No | 15 | 0.063 | 4 | 0 | 0.0 | 0 |
| CYB5B | CYB5B | O43169 | Cytochrome b5 type B | chr16 | GO:1990204 | Not Cancer Driver | No | 17 | 0.113 | 58 | 2 | 0.034 | 0 |
| CYB5R3_ENST00000352397 | CYB5R3 | P00387 | NADH-cytochrome b5 reductase 3 | chr22 | GO:1990204 | Not Cancer Driver | No | 42 | 0.14 | 24 | 3 | 0.125 | 9 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:1990204 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYBB | CYBB | P04839 | Cytochrome b-245 heavy chain | chrX | GO:1990204 | Not Cancer Driver | No | 109 | 0.191 | 11 | 3 | 0.273 | 65 |
| DBT | DBT | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | chr1 | GO:1990204 | Not Cancer Driver | No | 64 | 0.133 | 81 | 11 | 0.136 | 3 |
| DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | GO:1990204 | Not Cancer Driver | No | 63 | 0.097 | 294 | 42 | 0.143 | 0 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | GO:1990204 | Not Cancer Driver | No | 67 | 0.132 | 17 | 0 | 0.0 | 10 |
| DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | GO:1990204 | Not Cancer Driver | No | 53 | 0.117 | 190 | 32 | 0.168 | 1 |
| DUOX1 | DUOX1 | Q9NRD9 | Dual oxidase 1 | chr15 | GO:1990204 | Not Cancer Driver | No | 193 | 0.124 | 158 | 17 | 0.108 | 0 |
| DUOX2 | DUOX2 | Q9NRD8 | Dual oxidase 2 | chr15 | GO:1990204 | Not Cancer Driver | No | 245 | 0.158 | 182 | 25 | 0.137 | 3 |
| ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | GO:1990204 | Not Cancer Driver | No | 30 | 0.09 | 34 | 2 | 0.059 | 3 |
| ETFB_ENST00000309244 | ETFB | P38117 | Electron transfer flavoprotein subunit beta | chr19 | GO:1990204 | Not Cancer Driver | No | 37 | 0.145 | 38 | 4 | 0.105 | 2 |
| GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | GO:1990204 | Not Cancer Driver | No | 15 | 0.087 | 25 | 0 | 0.0 | 0 |
| GLDC | GLDC | P23378 | Glycine dehydrogenase (decarboxylating), mitochondrial | chr9 | GO:1990204 | Not Cancer Driver | No | 152 | 0.149 | 112 | 7 | 0.062 | 22 |
| GMPR | GMPR | P36959 | GMP reductase 1 | chr6 | GO:1990204 | Not Cancer Driver | No | 52 | 0.151 | 17 | 3 | 0.176 | 0 |
| GMPR2_ENST00000399440 | GMPR2 | Q9P2T1 | GMP reductase 2 | chr14 | GO:1990204 | Not Cancer Driver | No | 30 | 0.086 | 9 | 1 | 0.111 | 0 |
| GPD1 | GPD1 | P21695 | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic | chr12 | GO:1990204 | Not Cancer Driver | No | 59 | 0.169 | 2 | 0 | 0.0 | 1 |
| GPD1L | GPD1L | Q8N335 | Glycerol-3-phosphate dehydrogenase 1-like protein | chr3 | GO:1990204 | Not Cancer Driver | No | 40 | 0.114 | 13 | 1 | 0.077 | 0 |
| GPD2_ENST00000438166 | GPD2 | P43304 | Glycerol-3-phosphate dehydrogenase, mitochondrial | chr2 | GO:1990204 | Not Cancer Driver | No | 88 | 0.121 | 67 | 7 | 0.104 | 0 |
| HSD17B8 | HSD17B8 | Q92506 | (3R)-3-hydroxyacyl-CoA dehydrogenase | chr6 | GO:1990204 | Not Cancer Driver | No | 20 | 0.077 | 26 | 1 | 0.038 | 0 |
| IDH3A | IDH3A | P50213 | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | chr15 | GO:1990204 | Not Cancer Driver | No | 41 | 0.112 | 47 | 11 | 0.234 | 0 |
| IDH3B_ENST00000380843 | IDH3B | O43837 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | chr20 | GO:1990204 | Not Cancer Driver | No | 32 | 0.083 | 49 | 3 | 0.061 | 1 |
| IDH3G | IDH3G | P51553 | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial | chrX | GO:1990204 | Not Cancer Driver | No | 48 | 0.122 | 77 | 9 | 0.117 | 0 |
| LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | GO:1990204 | Not Cancer Driver | No | 40 | 0.12 | 9 | 0 | 0.0 | 0 |
| LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | GO:1990204 | Not Cancer Driver | No | 47 | 0.141 | 15 | 2 | 0.133 | 11 |
| MARC1 | MTARC1 | Q5VT66 | Mitochondrial amidoxime-reducing component 1 | chr1 | GO:1990204 | Not Cancer Driver | No | 49 | 0.145 | 26 | 6 | 0.231 | 0 |
| MRPS36 | MRPS36 | P82909 | Alpha-ketoglutarate dehydrogenase component 4 | chr5 | GO:1990204 | Not Cancer Driver | No | 12 | 0.117 | 103 | 12 | 0.117 | 0 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:1990204 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NCF2 | NCF2 | P19878 | Neutrophil cytosol factor 2 | chr1 | GO:1990204 | Not Cancer Driver | No | 97 | 0.184 | 183 | 34 | 0.186 | 14 |
| NCF4_ENST00000248899 | NCF4 | Q15080 | Neutrophil cytosol factor 4 | chr22 | GO:1990204 | Not Cancer Driver | No | 60 | 0.177 | 27 | 4 | 0.148 | 1 |
| NOX1 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:1990204 | Not Cancer Driver | No | 101 | 0.179 | 18 | 8 | 0.444 | 0 |
| NOX3 | NOX3 | Q9HBY0 | NADPH oxidase 3 | chr6 | GO:1990204 | Not Cancer Driver | No | 118 | 0.208 | 3 | 0 | 0.0 | 0 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:1990204 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| NOXA1 | NOXA1 | Q86UR1 | NADPH oxidase activator 1 | chr9 | GO:1990204 | Not Cancer Driver | No | 27 | 0.057 | 215 | 14 | 0.065 | 0 |
| NOXO1 | NOXO1 | Q8NFA2 | NADPH oxidase organizer 1 | chr16 | GO:1990204 | Not Cancer Driver | No | 29 | 0.077 | 182 | 9 | 0.049 | 0 |
| OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:1990204 | Not Cancer Driver | No | 150 | 0.147 | 106 | 19 | 0.179 | 0 |
| OGDHL | OGDHL | Q9ULD0 | 2-oxoglutarate dehydrogenase-like, mitochondrial | chr10 | GO:1990204 | Not Cancer Driver | No | 262 | 0.259 | 128 | 38 | 0.297 | 0 |
| P4HA1_ENST00000394890 | P4HA1 | P13674 | Prolyl 4-hydroxylase subunit alpha-1 | chr10 | GO:1990204 | Not Cancer Driver | No | 65 | 0.122 | 54 | 8 | 0.148 | 0 |
| P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | GO:1990204 | Not Cancer Driver | No | 61 | 0.12 | 79 | 15 | 0.19 | 1 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | GO:1990204 | Not Cancer Driver | No | 70 | 0.179 | 43 | 6 | 0.14 | 20 |
| PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | GO:1990204 | Not Cancer Driver | No | 32 | 0.089 | 4 | 0 | 0.0 | 2 |
| PDHX | PDHX | O00330 | Pyruvate dehydrogenase protein X component, mitochondrial | chr11 | GO:1990204 | Not Cancer Driver | No | 62 | 0.124 | 179 | 28 | 0.156 | 0 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | GO:1990204 | Not Cancer Driver | No | 52 | 0.119 | 50 | 10 | 0.2 | 0 |
| PDK2 | PDK2 | Q15119 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | chr17 | GO:1990204 | Not Cancer Driver | No | 45 | 0.111 | 35 | 4 | 0.114 | 0 |
| RRM1 | RRM1 | P23921 | Ribonucleoside-diphosphate reductase large subunit | chr11 | GO:1990204 | Not Cancer Driver | No | 74 | 0.093 | 41 | 7 | 0.171 | 0 |
| RRM2_ENST00000641198 | RRM2 | P31350 | Ribonucleoside-diphosphate reductase subunit M2 | chr2 | GO:1990204 | Not Cancer Driver | No | 40 | 0.103 | 48 | 0 | 0.0 | 0 |
| SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | GO:1990204 | Census | Yes | 115 | 0.173 | 71 | 13 | 0.183 | 7 |
| SDHB | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | chr1 | GO:1990204 | Census | Yes | 37 | 0.132 | 17 | 3 | 0.176 | 23 |
| SDHC | SDHC | Q99643 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | chr1 | GO:1990204 | Census | Yes | 16 | 0.095 | 0 | 0 | 0.0 | 0 |
| SDHD | SDHD | O14521 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | chr11 | GO:1990204 | Census | Yes | 22 | 0.138 | 0 | 0 | 0.0 | 10 |