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Total number of protein in "GO:1901653" GO term:  114

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:1901653 Not Cancer Driver No 199 0.13 123 22 0.179 1
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:1901653 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:1901653 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:1901653 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:1901653 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:1901653 Not Cancer Driver No 85 0.179 33 10 0.303 1
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:1901653 Not Cancer Driver No 155 0.157 168 14 0.083 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:1901653 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:1901653 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:1901653 Not Cancer Driver No 146 0.148 450 70 0.156 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:1901653 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:1901653 Not Cancer Driver No 200 0.197 115 29 0.252 31
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:1901653 Not Cancer Driver No 55 0.11 53 5 0.094 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:1901653 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:1901653 Not Cancer Driver No 22 0.114 34 6 0.176 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:1901653 Census Yes 174 0.139 397 59 0.149 6
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:1901653 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:1901653 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:1901653 Not Cancer Driver No 75 0.125 396 47 0.119 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:1901653 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:1901653 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:1901653 Not Cancer Driver No 45 0.104 186 19 0.102 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:1901653 Not Cancer Driver No 75 0.159 12 3 0.25 3
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:1901653 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:1901653 Not Cancer Driver No 48 0.164 5 1 0.2 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:1901653 Not Cancer Driver No 24 0.11 195 18 0.092 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:1901653 Not Cancer Driver No 368 0.245 73 22 0.301 140
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:1901653 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:1901653 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:1901653 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:1901653 Not Cancer Driver No 30 0.099 197 23 0.117 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:1901653 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:1901653 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:1901653 Census, Compendium Yes 64 0.185 0 0 0.0 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:1901653 Not Cancer Driver No 154 0.159 280 55 0.196 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:1901653 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:1901653 Not Cancer Driver No 62 0.145 21 6 0.286 2
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:1901653 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:1901653 Not Cancer Driver No 186 0.176 119 17 0.143 7
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:1901653 Not Cancer Driver No 466 0.162 110 16 0.145 360
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:1901653 Census Yes 51 0.165 99 30 0.303 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:1901653 Not Cancer Driver No 37 0.177 109 24 0.22 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:1901653 Census, Compendium Yes 70 0.104 595 68 0.114 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:1901653 Not Cancer Driver No 96 0.274 26 5 0.192 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:1901653 Not Cancer Driver No 92 0.171 70 13 0.186 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:1901653 Not Cancer Driver No 16 0.034 56 2 0.036 4
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:1901653 Not Cancer Driver No 10 0.049 97 4 0.041 1
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:1901653 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:1901653 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:1901653 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:1901653 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:1901653 Not Cancer Driver No 124 0.224 63 14 0.222 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:1901653 Not Cancer Driver No 40 0.122 15 1 0.067 14
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:1901653 Not Cancer Driver No 57 0.153 12 0 0.0 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:1901653 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:1901653 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:1901653 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:1901653 Not Cancer Driver No 56 0.133 146 13 0.089 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:1901653 Not Cancer Driver No 59 0.112 335 37 0.11 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:1901653 Not Cancer Driver No 61 0.115 251 28 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:1901653 Not Cancer Driver No 20 0.129 17 6 0.353 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:1901653 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:1901653 Not Cancer Driver No 45 0.231 87 23 0.264 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:1901653 Not Cancer Driver No 254 0.246 97 27 0.278 0
KLF1 KLF1 Q13351 Krueppel-like factor 1 chr19 GO:1901653 Not Cancer Driver No 33 0.091 279 23 0.082 1
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 GO:1901653 Not Cancer Driver No 57 0.111 308 38 0.123 2
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 GO:1901653 Not Cancer Driver No 66 0.159 273 48 0.176 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:1901653 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 GO:1901653 Not Cancer Driver No 53 0.154 243 38 0.156 0
LDOC1 LDOC1 O95751 Protein LDOC1 chrX GO:1901653 Not Cancer Driver No 48 0.329 23 10 0.435 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:1901653 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:1901653 Not Cancer Driver No 181 0.259 12 8 0.667 25
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:1901653 Not Cancer Driver No 664 0.146 317 52 0.164 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:1901653 Census, Compendium Yes 56 0.114 297 37 0.125 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:1901653 Not Cancer Driver No 25 0.104 207 22 0.106 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:1901653 Census, Compendium Yes 80 0.182 299 46 0.154 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:1901653 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:1901653 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:1901653 Not Cancer Driver No 57 0.133 172 25 0.145 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:1901653 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:1901653 Not Cancer Driver No 169 0.163 40 4 0.1 15
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:1901653 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:1901653 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:1901653 Census Yes 83 0.133 298 37 0.124 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:1901653 Census, Compendium Yes 168 0.211 57 8 0.14 25
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:1901653 Not Cancer Driver No 119 0.117 320 34 0.106 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:1901653 Not Cancer Driver No 142 0.228 110 28 0.255 1
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:1901653 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:1901653 Not Cancer Driver No 313 0.257 481 104 0.216 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:1901653 Not Cancer Driver No 47 0.058 695 35 0.05 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:1901653 Compendium Yes 79 0.117 43 9 0.209 0
PRNP PRNP P04156 Major prion protein chr20 GO:1901653 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:1901653 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:1901653 Not Cancer Driver No 141 0.175 364 62 0.17 4
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:1901653 Not Cancer Driver No 65 0.111 159 17 0.107 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:1901653 Compendium Yes 75 0.136 400 48 0.12 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:1901653 Not Cancer Driver No 63 0.117 143 20 0.14 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:1901653 Not Cancer Driver No 14 0.1 29 4 0.138 0
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:1901653 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:1901653 Not Cancer Driver No 68 0.14 61 10 0.164 2
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:1901653 Not Cancer Driver No 92 0.14 224 29 0.129 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:1901653 Not Cancer Driver No 33 0.081 85 7 0.082 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:1901653 Not Cancer Driver No 31 0.088 221 22 0.1 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:1901653 Not Cancer Driver No 154 0.127 367 51 0.139 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:1901653 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:1901653 Not Cancer Driver No 99 0.124 1 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:1901653 Not Cancer Driver No 24 0.103 45 3 0.067 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:1901653 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:1901653 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:1901653 Not Cancer Driver No 69 0.11 385 38 0.099 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:1901653 Census Yes 128 0.168 38 9 0.237 39
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:1901653 Not Cancer Driver No 191 0.145 249 29 0.116 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:1901653 Not Cancer Driver No 188 0.254 110 28 0.255 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:1901653 Not Cancer Driver No 84 0.18 316 57 0.18 1