Total number of protein in "GO:0090501" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABT1 | ABT1 | Q9ULW3 | Activator of basal transcription 1 | chr6 | GO:0090501 | Not Cancer Driver | No | 56 | 0.206 | 157 | 30 | 0.191 | 0 |
| ANGEL1 | ANGEL1 | Q9UNK9 | Protein angel homolog 1 | chr14 | GO:0090501 | Not Cancer Driver | No | 85 | 0.127 | 160 | 21 | 0.131 | 0 |
| ANGEL2 | ANGEL2 | Q5VTE6 | Protein angel homolog 2 | chr1 | GO:0090501 | Not Cancer Driver | No | 56 | 0.103 | 48 | 6 | 0.125 | 0 |
| AZGP1 | AZGP1 | P25311 | Zinc-alpha-2-glycoprotein | chr7 | GO:0090501 | Not Cancer Driver | No | 59 | 0.198 | 41 | 10 | 0.244 | 0 |
| BOP1 | BOP1 | Q14137 | Ribosome biogenesis protein BOP1 | chr8 | GO:0090501 | Not Cancer Driver | No | 20 | 0.027 | 304 | 19 | 0.062 | 0 |
| CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | GO:0090501 | Not Cancer Driver | No | 346 | 0.146 | 464 | 56 | 0.121 | 12 |
| CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | GO:0090501 | Not Cancer Driver | No | 84 | 0.156 | 354 | 66 | 0.186 | 0 |
| CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | GO:0090501 | Not Cancer Driver | No | 58 | 0.105 | 37 | 3 | 0.081 | 0 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0090501 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0090501 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0090501 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| CPSF1 | CPSF1 | Q10570 | Cleavage and polyadenylation specificity factor subunit 1 | chr8 | GO:0090501 | Not Cancer Driver | No | 177 | 0.123 | 298 | 42 | 0.141 | 0 |
| CPSF2 | CPSF2 | Q9P2I0 | Cleavage and polyadenylation specificity factor subunit 2 | chr14 | GO:0090501 | Not Cancer Driver | No | 76 | 0.097 | 231 | 22 | 0.095 | 0 |
| CPSF3 | CPSF3 | Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 | chr2 | GO:0090501 | Not Cancer Driver | No | 78 | 0.114 | 56 | 9 | 0.161 | 0 |
| CPSF4 | CPSF4 | O95639 | Cleavage and polyadenylation specificity factor subunit 4 | chr7 | GO:0090501 | Not Cancer Driver | No | 36 | 0.134 | 89 | 11 | 0.124 | 0 |
| CPSF4L | CPSF4L | A6NMK7 | Putative cleavage and polyadenylation specificity factor subunit 4-like protein | chr17 | GO:0090501 | Not Cancer Driver | No | 7 | 0.039 | 0 | 0 | 0.0 | 0 |
| CPSF6_ENST00000435070 | CPSF6 | Q16630 | Cleavage and polyadenylation specificity factor subunit 6 | chr12 | GO:0090501 | Not Cancer Driver | No | 85 | 0.154 | 484 | 75 | 0.155 | 0 |
| CPSF7_ENST00000394888 | CPSF7 | Q8N684 | Cleavage and polyadenylation specificity factor subunit 7 | chr11 | GO:0090501 | Not Cancer Driver | No | 55 | 0.117 | 398 | 52 | 0.131 | 0 |
| CSTF2T | CSTF2T | Q9H0L4 | Cleavage stimulation factor subunit 2 tau variant | chr10 | GO:0090501 | Not Cancer Driver | No | 87 | 0.141 | 507 | 75 | 0.148 | 0 |
| CSTF2_ENST00000372972 | CSTF2 | P33240 | Cleavage stimulation factor subunit 2 | chrX | GO:0090501 | Not Cancer Driver | No | 85 | 0.147 | 484 | 72 | 0.149 | 0 |
| CSTF3 | CSTF3 | Q12996 | Cleavage stimulation factor subunit 3 | chr11 | GO:0090501 | Not Cancer Driver | No | 82 | 0.114 | 122 | 15 | 0.123 | 0 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0090501 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0090501 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0090501 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DIS3 | DIS3 | Q9Y2L1 | Exosome complex exonuclease RRP44 | chr13 | GO:0090501 | Compendium | Yes | 121 | 0.126 | 235 | 32 | 0.136 | 0 |
| DIS3L | DIS3L | Q8TF46 | DIS3-like exonuclease 1 | chr15 | GO:0090501 | Not Cancer Driver | No | 111 | 0.105 | 139 | 20 | 0.144 | 0 |
| DIS3L2 | DIS3L2 | Q8IYB7 | DIS3-like exonuclease 2 | chr2 | GO:0090501 | Not Cancer Driver | No | 114 | 0.129 | 264 | 22 | 0.083 | 1 |
| ELAC1 | ELAC1 | Q9H777 | Zinc phosphodiesterase ELAC protein 1 | chr18 | GO:0090501 | Not Cancer Driver | No | 40 | 0.11 | 47 | 4 | 0.085 | 0 |
| ELAC2 | ELAC2 | Q9BQ52 | Zinc phosphodiesterase ELAC protein 2 | chr17 | GO:0090501 | Not Cancer Driver | No | 86 | 0.104 | 208 | 30 | 0.144 | 10 |
| ERI1_ENST00000519292 | ERI1 | Q8IV48 | 3'-5' exoribonuclease 1 | chr8 | GO:0090501 | Not Cancer Driver | No | 40 | 0.115 | 78 | 13 | 0.167 | 0 |
| ERI2 | ERI2 | A8K979 | ERI1 exoribonuclease 2 | chr16 | GO:0090501 | Not Cancer Driver | No | 34 | 0.049 | 288 | 8 | 0.028 | 0 |
| ERI3 | ERI3 | O43414 | ERI1 exoribonuclease 3 | chr1 | GO:0090501 | Not Cancer Driver | No | 49 | 0.145 | 29 | 0 | 0.0 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0090501 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0090501 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0090501 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EXOSC2 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0090501 | Not Cancer Driver | No | 21 | 0.072 | 47 | 6 | 0.128 | 2 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0090501 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0090501 | Not Cancer Driver | No | 34 | 0.139 | 23 | 0 | 0.0 | 0 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | GO:0090501 | Not Cancer Driver | No | 43 | 0.183 | 31 | 3 | 0.097 | 0 |
| EXOSC7 | EXOSC7 | Q15024 | Exosome complex component RRP42 | chr3 | GO:0090501 | Not Cancer Driver | No | 41 | 0.141 | 8 | 1 | 0.125 | 0 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | GO:0090501 | Not Cancer Driver | No | 20 | 0.072 | 28 | 1 | 0.036 | 2 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0090501 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FIP1L1 | FIP1L1 | Q6UN15 | Pre-mRNA 3'-end-processing factor FIP1 | chr4 | GO:0090501 | Census | Yes | 88 | 0.148 | 572 | 85 | 0.149 | 0 |
| HELZ2 | HELZ2 | Q9BYK8 | Helicase with zinc finger domain 2 | chr20 | GO:0090501 | Not Cancer Driver | No | 320 | 0.121 | 594 | 84 | 0.141 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0090501 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| ISG20L2 | ISG20L2 | Q9H9L3 | Interferon-stimulated 20 kDa exonuclease-like 2 | chr1 | GO:0090501 | Not Cancer Driver | No | 46 | 0.13 | 232 | 33 | 0.142 | 0 |
| N4BP1 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0090501 | Not Cancer Driver | No | 108 | 0.121 | 432 | 58 | 0.134 | 0 |
| NCBP1 | NCBP1 | Q09161 | Nuclear cap-binding protein subunit 1 | chr9 | GO:0090501 | Not Cancer Driver | No | 88 | 0.111 | 89 | 8 | 0.09 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0090501 | Not Cancer Driver | No | 33 | 0.077 | 89 | 3 | 0.034 | 0 |
| NOL9 | NOL9 | Q5SY16 | Polynucleotide 5'-hydroxyl-kinase NOL9 | chr1 | GO:0090501 | Not Cancer Driver | No | 73 | 0.104 | 102 | 8 | 0.078 | 0 |
| NOP14 | NOP14 | P78316 | Nucleolar protein 14 | chr4 | GO:0090501 | Not Cancer Driver | No | 87 | 0.102 | 521 | 46 | 0.088 | 0 |
| NOP9 | NOP9 | Q86U38 | Nucleolar protein 9 | chr14 | GO:0090501 | Not Cancer Driver | No | 53 | 0.083 | 166 | 14 | 0.084 | 0 |
| NUDT21 | NUDT21 | O43809 | Cleavage and polyadenylation specificity factor subunit 5 | chr16 | GO:0090501 | Not Cancer Driver | No | 21 | 0.093 | 37 | 3 | 0.081 | 0 |
| PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | GO:0090501 | Not Cancer Driver | No | 139 | 0.116 | 78 | 10 | 0.128 | 0 |
| PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | GO:0090501 | Not Cancer Driver | No | 104 | 0.117 | 323 | 35 | 0.108 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0090501 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PCF11 | PCF11 | O94913 | Pre-mRNA cleavage complex 2 protein Pcf11 | chr11 | GO:0090501 | Not Cancer Driver | No | 211 | 0.136 | 1250 | 189 | 0.151 | 0 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0090501 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PNLDC1_ENST00000610273 | PNLDC1 | Q8NA58 | Poly(A)-specific ribonuclease PNLDC1 | chr6 | GO:0090501 | Not Cancer Driver | No | 105 | 0.202 | 6 | 0 | 0.0 | 1 |
| PNPT1 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0090501 | Not Cancer Driver | No | 86 | 0.11 | 115 | 10 | 0.087 | 2 |
| POLR2I | POLR2I | P36954 | DNA-directed RNA polymerase II subunit RPB9 | chr19 | GO:0090501 | Not Cancer Driver | No | 21 | 0.168 | 22 | 5 | 0.227 | 0 |
| POLR3K | POLR3K | Q9Y2Y1 | DNA-directed RNA polymerase III subunit RPC10 | chr16 | GO:0090501 | Not Cancer Driver | No | 10 | 0.093 | 0 | 0 | 0.0 | 1 |
| PPP1R8 | PPP1R8 | Q12972 | Nuclear inhibitor of protein phosphatase 1 | chr1 | GO:0090501 | Not Cancer Driver | No | 24 | 0.068 | 251 | 19 | 0.076 | 0 |
| RCL1 | RCL1 | Q9Y2P8 | RNA 3'-terminal phosphate cyclase-like protein | chr9 | GO:0090501 | Not Cancer Driver | No | 40 | 0.107 | 12 | 0 | 0.0 | 0 |
| REXO2 | REXO2 | Q9Y3B8 | Oligoribonuclease, mitochondrial | chr11 | GO:0090501 | Not Cancer Driver | No | 19 | 0.08 | 43 | 4 | 0.093 | 0 |
| RNASE1_ENST00000412779 | RNASE1 | P07998 | Ribonuclease pancreatic | chr14 | GO:0090501 | Not Cancer Driver | No | 17 | 0.109 | 49 | 11 | 0.224 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0090501 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE3 | RNASE3 | P12724 | Eosinophil cationic protein | chr14 | GO:0090501 | Not Cancer Driver | No | 37 | 0.231 | 8 | 0 | 0.0 | 0 |
| RNASE4_ENST00000555597 | RNASE4 | P34096 | Ribonuclease 4 | chr14 | GO:0090501 | Not Cancer Driver | No | 24 | 0.163 | 9 | 2 | 0.222 | 0 |
| RNASE6 | RNASE6 | Q93091 | Ribonuclease K6 | chr14 | GO:0090501 | Not Cancer Driver | No | 26 | 0.173 | 0 | 0 | 0.0 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | GO:0090501 | Not Cancer Driver | No | 27 | 0.173 | 42 | 4 | 0.095 | 0 |
| RPP40 | RPP40 | O75818 | Ribonuclease P protein subunit p40 | chr6 | GO:0090501 | Not Cancer Driver | No | 51 | 0.14 | 5 | 0 | 0.0 | 0 |
| RPS21 | RPS21 | P63220 | 40S ribosomal protein S21 | chr20 | GO:0090501 | Not Cancer Driver | No | 8 | 0.096 | 0 | 0 | 0.0 | 0 |
| SAMHD1 | SAMHD1 | Q9Y3Z3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | chr20 | GO:0090501 | Not Cancer Driver | No | 104 | 0.166 | 91 | 14 | 0.154 | 13 |
| TBL3 | TBL3 | Q12788 | Transducin beta-like protein 3 | chr16 | GO:0090501 | Not Cancer Driver | No | 82 | 0.101 | 48 | 8 | 0.167 | 0 |
| TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | GO:0090501 | Not Cancer Driver | No | 44 | 0.086 | 210 | 22 | 0.105 | 10 |
| TRIR | TRIR | Q9BQ61 | Telomerase RNA component interacting RNase | chr19 | GO:0090501 | Not Cancer Driver | No | 17 | 0.097 | 176 | 17 | 0.097 | 0 |
| TUT1_ENST00000476907 | TUT1 | Q9H6E5 | Speckle targeted PIP5K1A-regulated poly(A) polymerase | chr11 | GO:0090501 | Not Cancer Driver | No | 97 | 0.111 | 410 | 50 | 0.122 | 0 |
| USB1 | USB1 | Q9BQ65 | U6 snRNA phosphodiesterase 1 | chr16 | GO:0090501 | Not Cancer Driver | No | 28 | 0.106 | 76 | 5 | 0.066 | 0 |
| UTP20 | UTP20 | O75691 | Small subunit processome component 20 homolog | chr12 | GO:0090501 | Not Cancer Driver | No | 324 | 0.116 | 314 | 35 | 0.111 | 0 |
| UTP23 | UTP23 | Q9BRU9 | rRNA-processing protein UTP23 homolog | chr8 | GO:0090501 | Not Cancer Driver | No | 35 | 0.141 | 97 | 16 | 0.165 | 0 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:0090501 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |
| XRN2 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0090501 | Not Cancer Driver | No | 129 | 0.136 | 427 | 63 | 0.148 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0090501 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZNRD1 | POLR1H | Q9P1U0 | DNA-directed RNA polymerase I subunit RPA12 | chr6 | GO:0090501 | Not Cancer Driver | No | 6 | 0.048 | 14 | 1 | 0.071 | 0 |