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Total number of protein in "GO:0090304" GO term:  737

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 GO:0090304 Census Yes 150 0.253 63 20 0.317 0
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0090304 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0090304 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0090304 Not Cancer Driver No 40 0.097 157 20 0.127 0
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 GO:0090304 Not Cancer Driver No 56 0.206 157 30 0.191 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0090304 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0090304 Not Cancer Driver No 63 0.104 163 23 0.141 0
ADAD1 ADAD1 Q96M93 Adenosine deaminase domain-containing protein 1 chr4 GO:0090304 Not Cancer Driver No 158 0.274 78 24 0.308 0
ADAD2_ENST00000315906 ADAD2 Q8NCV1 Adenosine deaminase domain-containing protein 2 chr16 GO:0090304 Not Cancer Driver No 87 0.149 191 39 0.204 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0090304 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0090304 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADARB2 ADARB2 Q9NS39 Double-stranded RNA-specific editase B2 chr10 GO:0090304 Not Cancer Driver No 154 0.208 331 69 0.208 0
ADAT2 ADAT2 Q7Z6V5 tRNA-specific adenosine deaminase 2 chr6 GO:0090304 Not Cancer Driver No 26 0.136 69 9 0.13 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0090304 Not Cancer Driver No 32 0.088 49 4 0.082 1
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:0090304 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0090304 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0090304 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:0090304 Not Cancer Driver No 100 0.116 183 24 0.131 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0090304 Not Cancer Driver No 56 0.283 0 0 0.0 8
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0090304 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALKBH2_ENST00000343075 ALKBH2 Q6NS38 DNA oxidative demethylase ALKBH2 chr12 GO:0090304 Not Cancer Driver No 34 0.13 73 14 0.192 0
ALKBH3 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0090304 Not Cancer Driver No 42 0.147 157 25 0.159 0
ALKBH4 ALKBH4 Q9NXW9 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 chr7 GO:0090304 Not Cancer Driver No 39 0.129 14 2 0.143 0
ALKBH5 ALKBH5 Q6P6C2 RNA demethylase ALKBH5 chr17 GO:0090304 Not Cancer Driver No 41 0.104 200 23 0.115 0
ANG ANG P03950 Angiogenin chr14 GO:0090304 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGEL1 ANGEL1 Q9UNK9 Protein angel homolog 1 chr14 GO:0090304 Not Cancer Driver No 85 0.127 160 21 0.131 0
ANGEL2 ANGEL2 Q5VTE6 Protein angel homolog 2 chr1 GO:0090304 Not Cancer Driver No 56 0.103 48 6 0.125 0
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 GO:0090304 Not Cancer Driver No 62 0.033 1144 34 0.03 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0090304 Not Cancer Driver No 126 0.115 316 31 0.098 1
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0090304 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0090304 Not Cancer Driver No 64 0.125 407 57 0.14 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0090304 Not Cancer Driver No 62 0.263 13 1 0.077 0
APOBEC2 APOBEC2 Q9Y235 C->U-editing enzyme APOBEC-2 chr6 GO:0090304 Not Cancer Driver No 38 0.17 36 3 0.083 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0090304 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOBEC3B APOBEC3B Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B chr22 GO:0090304 Census Yes 61 0.16 1 0 0.0 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 GO:0090304 Not Cancer Driver No 28 0.147 2 0 0.0 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 GO:0090304 Not Cancer Driver No 43 0.111 3 0 0.0 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0090304 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0090304 Not Cancer Driver No 61 0.159 0 0 0.0 0
APOBEC3H_ENST00000613677 APOBEC3H Q6NTF7 DNA dC->dU-editing enzyme APOBEC-3H chr22 GO:0090304 Not Cancer Driver No 39 0.195 0 0 0.0 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0090304 Not Cancer Driver No 36 0.101 101 6 0.059 9
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0090304 Not Cancer Driver No 279 0.127 87 8 0.092 0
ASZ1 ASZ1 Q8WWH4 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 chr7 GO:0090304 Not Cancer Driver No 86 0.181 53 10 0.189 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0090304 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0090304 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0090304 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0090304 Compendium Yes 160 0.126 1136 139 0.122 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0090304 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0090304 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0090304 Census, Compendium Yes 114 0.135 547 77 0.141 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0090304 Not Cancer Driver No 10 0.112 11 2 0.182 1
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0090304 Not Cancer Driver No 28 0.224 119 25 0.21 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 GO:0090304 Not Cancer Driver No 186 0.098 1283 118 0.092 0
BCDIN3D BCDIN3D Q7Z5W3 RNA 5'-monophosphate methyltransferase chr12 GO:0090304 Not Cancer Driver No 27 0.092 44 2 0.045 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0090304 Census, Compendium Yes 156 0.174 699 114 0.163 2
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 GO:0090304 Not Cancer Driver No 104 0.126 311 44 0.141 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0090304 Census Yes 153 0.108 667 70 0.105 8
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 GO:0090304 Not Cancer Driver No 20 0.027 304 19 0.062 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0090304 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0090304 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0090304 Census Yes 174 0.139 397 59 0.149 6
BTBD18 BTBD18 B2RXH4 BTB/POZ domain-containing protein 18 chr11 GO:0090304 Not Cancer Driver No 29 0.041 567 25 0.044 0
BUD23_ENST00000265758 BUD23 O43709 Probable 18S rRNA (guanine-N(7))-methyltransferase chr7 GO:0090304 Not Cancer Driver No 41 0.146 83 11 0.133 0
C14orf39 SIX6OS1 Q8N1H7 Protein SIX6OS1 chr14 GO:0090304 Not Cancer Driver No 128 0.218 326 76 0.233 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:0090304 Not Cancer Driver No 91 0.136 632 88 0.139 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0090304 Not Cancer Driver No 71 0.203 0 0 0.0 0
C9orf64 C9orf64 Q5T6V5 Queuosine salvage protein chr9 GO:0090304 Not Cancer Driver No 43 0.126 1 0 0.0 0
CARS2 CARS2 Q9HA77 Probable cysteine--tRNA ligase, mitochondrial chr13 GO:0090304 Not Cancer Driver No 51 0.09 87 8 0.092 1
CARS_ENST00000397111 CARS1 P49589 Cysteine--tRNA ligase, cytoplasmic chr11 GO:0090304 Not Cancer Driver No 97 0.13 184 35 0.19 3
CAVIN1 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 GO:0090304 Not Cancer Driver No 66 0.169 280 50 0.179 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0090304 Not Cancer Driver No 72 0.147 373 49 0.131 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0090304 Not Cancer Driver No 61 0.111 160 19 0.119 103
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0090304 Not Cancer Driver No 56 0.15 13 2 0.154 0
CD3EAP_ENST00000309424 POLR1G O15446 DNA-directed RNA polymerase I subunit RPA34 chr19 GO:0090304 Not Cancer Driver No 52 0.102 491 50 0.102 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0090304 Not Cancer Driver No 56 0.215 24 7 0.292 32
CDADC1 CDADC1 Q9BWV3 Cytidine and dCMP deaminase domain-containing protein 1 chr13 GO:0090304 Not Cancer Driver No 52 0.101 122 13 0.107 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0090304 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0090304 Not Cancer Driver No 41 0.118 38 5 0.132 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 GO:0090304 Not Cancer Driver No 80 0.138 120 14 0.117 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:0090304 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0090304 Not Cancer Driver No 82 0.176 201 33 0.164 0
CMTR1 CMTR1 Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 chr6 GO:0090304 Not Cancer Driver No 81 0.097 176 20 0.114 0
CMTR2 CMTR2 Q8IYT2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 chr16 GO:0090304 Compendium Yes 101 0.131 10 2 0.2 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0090304 Census Yes 11 0.062 19 0 0.0 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0090304 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0090304 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0090304 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0090304 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0090304 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0090304 Not Cancer Driver No 30 0.103 6 0 0.0 0
CPSF1 CPSF1 Q10570 Cleavage and polyadenylation specificity factor subunit 1 chr8 GO:0090304 Not Cancer Driver No 177 0.123 298 42 0.141 0
CPSF2 CPSF2 Q9P2I0 Cleavage and polyadenylation specificity factor subunit 2 chr14 GO:0090304 Not Cancer Driver No 76 0.097 231 22 0.095 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 GO:0090304 Not Cancer Driver No 78 0.114 56 9 0.161 0
CPSF4 CPSF4 O95639 Cleavage and polyadenylation specificity factor subunit 4 chr7 GO:0090304 Not Cancer Driver No 36 0.134 89 11 0.124 0
CPSF4L CPSF4L A6NMK7 Putative cleavage and polyadenylation specificity factor subunit 4-like protein chr17 GO:0090304 Not Cancer Driver No 7 0.039 0 0 0.0 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 GO:0090304 Not Cancer Driver No 85 0.154 484 75 0.155 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 GO:0090304 Not Cancer Driver No 55 0.117 398 52 0.131 0
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 GO:0090304 Not Cancer Driver No 11 0.074 113 4 0.035 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0090304 Not Cancer Driver No 72 0.121 100 12 0.12 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0090304 Not Cancer Driver No 118 0.148 204 29 0.142 0
CSTF2T CSTF2T Q9H0L4 Cleavage stimulation factor subunit 2 tau variant chr10 GO:0090304 Not Cancer Driver No 87 0.141 507 75 0.148 0
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0090304 Not Cancer Driver No 85 0.147 484 72 0.149 0
CSTF3 CSTF3 Q12996 Cleavage stimulation factor subunit 3 chr11 GO:0090304 Not Cancer Driver No 82 0.114 122 15 0.123 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 GO:0090304 Census, Compendium Yes 151 0.208 481 83 0.173 1
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 GO:0090304 Not Cancer Driver No 136 0.205 266 61 0.229 0
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 GO:0090304 Not Cancer Driver No 12 0.034 60 1 0.017 0
CTU2_ENST00000453996 CTU2 Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 chr16 GO:0090304 Not Cancer Driver No 46 0.089 137 11 0.08 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0090304 Not Cancer Driver No 138 0.151 207 38 0.184 2
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0090304 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0090304 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0090304 Not Cancer Driver No 24 0.153 128 19 0.148 0
DALRD3 DALRD3 Q5D0E6 DALR anticodon-binding domain-containing protein 3 chr3 GO:0090304 Not Cancer Driver No 49 0.09 40 4 0.1 0
DARS DARS1 P14868 Aspartate--tRNA ligase, cytoplasmic chr2 GO:0090304 Not Cancer Driver No 55 0.11 110 21 0.191 8
DARS2 DARS2 Q6PI48 Aspartate--tRNA ligase, mitochondrial chr1 GO:0090304 Not Cancer Driver No 63 0.098 91 11 0.121 11
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0090304 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0090304 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0090304 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 GO:0090304 Not Cancer Driver No 46 0.079 382 31 0.081 0
DCP1B DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 GO:0090304 Not Cancer Driver No 82 0.133 406 63 0.155 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0090304 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0090304 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0090304 Not Cancer Driver No 14 0.082 88 9 0.102 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0090304 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0090304 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0090304 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0090304 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 GO:0090304 Not Cancer Driver No 121 0.148 426 71 0.167 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0090304 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0090304 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 GO:0090304 Not Cancer Driver No 115 0.159 315 49 0.156 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0090304 Census Yes 74 0.121 225 23 0.102 0
DEDD2 DEDD2 Q8WXF8 DNA-binding death effector domain-containing protein 2 chr19 GO:0090304 Not Cancer Driver No 42 0.129 133 25 0.188 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0090304 Not Cancer Driver No 47 0.142 113 18 0.159 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 GO:0090304 Not Cancer Driver No 37 0.109 27 1 0.037 0
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 GO:0090304 Census, Compendium Yes 102 0.132 466 57 0.122 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0090304 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0090304 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0090304 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0090304 Compendium Yes 121 0.126 235 32 0.136 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:0090304 Not Cancer Driver No 111 0.105 139 20 0.144 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0090304 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0090304 Not Cancer Driver No 62 0.121 145 29 0.2 24
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0090304 Not Cancer Driver No 49 0.105 269 28 0.104 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0090304 Not Cancer Driver No 39 0.115 49 5 0.102 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0090304 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 GO:0090304 Not Cancer Driver No 52 0.145 141 21 0.149 2
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0090304 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0090304 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0090304 Not Cancer Driver No 53 0.147 14 1 0.071 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0090304 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0090304 Census, Compendium Yes 194 0.213 371 59 0.159 16
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 GO:0090304 Not Cancer Driver No 153 0.179 328 71 0.216 16
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0090304 Not Cancer Driver No 83 0.215 10 1 0.1 0
DNTT DNTT P04053 DNA nucleotidylexotransferase chr10 GO:0090304 Not Cancer Driver No 106 0.208 66 16 0.242 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 GO:0090304 Not Cancer Driver No 50 0.088 217 13 0.06 6
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0090304 Census, Compendium Yes 175 0.127 682 100 0.147 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 GO:0090304 Not Cancer Driver No 45 0.215 93 26 0.28 0
DTD2_ENST00000356180 DTD2 Q96FN9 D-aminoacyl-tRNA deacylase 2 chr14 GO:0090304 Not Cancer Driver No 12 0.071 11 1 0.091 0
DUS1L_ENST00000306796 DUS1L Q6P1R4 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like chr17 GO:0090304 Not Cancer Driver No 52 0.11 110 10 0.091 0
DUS2 DUS2 Q9NX74 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like chr16 GO:0090304 Not Cancer Driver No 48 0.097 117 10 0.085 0
DUS3L DUS3L Q96G46 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like chr19 GO:0090304 Not Cancer Driver No 82 0.126 234 27 0.115 0
DUS4L DUS4L O95620 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like chr7 GO:0090304 Not Cancer Driver No 38 0.12 3 0 0.0 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0090304 Not Cancer Driver No 46 0.116 143 17 0.119 0
EARS2_ENST00000449606 EARS2 Q5JPH6 Probable glutamate--tRNA ligase, mitochondrial chr16 GO:0090304 Not Cancer Driver No 56 0.107 99 14 0.141 14
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 GO:0090304 Not Cancer Driver No 43 0.085 185 22 0.119 1
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 GO:0090304 Not Cancer Driver No 144 0.103 702 69 0.098 0
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 GO:0090304 Not Cancer Driver No 182 0.14 701 97 0.138 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0090304 Not Cancer Driver No 142 0.117 585 71 0.121 0
ELAC1 ELAC1 Q9H777 Zinc phosphodiesterase ELAC protein 1 chr18 GO:0090304 Not Cancer Driver No 40 0.11 47 4 0.085 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0090304 Not Cancer Driver No 86 0.104 208 30 0.144 10
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0090304 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELL2 ELL2 O00472 RNA polymerase II elongation factor ELL2 chr5 GO:0090304 Not Cancer Driver No 90 0.141 421 63 0.15 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0090304 Not Cancer Driver No 50 0.126 186 13 0.07 0
ELP1 ELP1 O95163 Elongator complex protein 1 chr9 GO:0090304 Not Cancer Driver No 143 0.107 157 23 0.146 2
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0090304 Not Cancer Driver No 60 0.11 19 4 0.211 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0090304 Not Cancer Driver No 11 0.037 61 1 0.016 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0090304 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 GO:0090304 Not Cancer Driver No 204 0.135 372 62 0.167 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0090304 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0090304 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0090304 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0090304 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0090304 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0090304 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0090304 Not Cancer Driver No 25 0.063 53 8 0.151 7
EREG EREG O14944 Proepiregulin chr4 GO:0090304 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERI1_ENST00000519292 ERI1 Q8IV48 3'-5' exoribonuclease 1 chr8 GO:0090304 Not Cancer Driver No 40 0.115 78 13 0.167 0
ERI2 ERI2 A8K979 ERI1 exoribonuclease 2 chr16 GO:0090304 Not Cancer Driver No 34 0.049 288 8 0.028 0
ERI3 ERI3 O43414 ERI1 exoribonuclease 3 chr1 GO:0090304 Not Cancer Driver No 49 0.145 29 0 0.0 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0090304 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0090304 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXD1_ENST00000314992 EXD1 Q8NHP7 piRNA biogenesis protein EXD1 chr15 GO:0090304 Not Cancer Driver No 85 0.165 173 26 0.15 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0090304 Not Cancer Driver No 58 0.093 176 15 0.085 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0090304 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0090304 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0090304 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0090304 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0090304 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0090304 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0090304 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0090304 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0090304 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0090304 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0090304 Not Cancer Driver No 58 0.132 154 18 0.117 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0090304 Census, Compendium Yes 120 0.161 284 44 0.155 11
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0090304 Not Cancer Driver No 78 0.128 169 23 0.136 5
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0090304 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0090304 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0090304 Not Cancer Driver No 268 0.131 898 128 0.143 0
FARS2_ENST00000274680 FARS2 O95363 Phenylalanine--tRNA ligase, mitochondrial chr6 GO:0090304 Not Cancer Driver No 66 0.146 73 17 0.233 4
FARSA FARSA Q9Y285 Phenylalanine--tRNA ligase alpha subunit chr19 GO:0090304 Not Cancer Driver No 75 0.148 120 25 0.208 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 GO:0090304 Not Cancer Driver No 71 0.121 0 0 0.0 8
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0090304 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 GO:0090304 Not Cancer Driver No 46 0.143 145 22 0.152 0
FBLL1 FBLL1 A6NHQ2 rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 chr5 GO:0090304 Not Cancer Driver No 18 0.054 140 1 0.007 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0090304 Census Yes 35 0.092 111 11 0.099 0
FIP1L1 FIP1L1 Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 chr4 GO:0090304 Census Yes 88 0.148 572 85 0.149 0
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 GO:0090304 Not Cancer Driver No 75 0.229 17 1 0.059 0
FOS FOS P01100 Protein c-Fos chr14 GO:0090304 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0090304 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0090304 Census, Compendium Yes 39 0.104 257 20 0.078 26
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0090304 Not Cancer Driver No 67 0.133 53 10 0.189 3
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX GO:0090304 Not Cancer Driver No 44 0.134 89 14 0.157 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 GO:0090304 Not Cancer Driver No 103 0.122 533 66 0.124 0
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 GO:0090304 Not Cancer Driver No 23 0.106 141 14 0.099 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 GO:0090304 Not Cancer Driver No 61 0.083 75 9 0.12 17
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 GO:0090304 Not Cancer Driver No 88 0.139 548 77 0.141 0
GATB GATB O75879 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial chr4 GO:0090304 Not Cancer Driver No 79 0.142 138 26 0.188 0
GATC GATC O43716 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial chr12 GO:0090304 Not Cancer Driver No 18 0.132 27 4 0.148 1
GCNA GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0090304 Not Cancer Driver No 155 0.224 513 122 0.238 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0090304 Not Cancer Driver No 109 0.12 339 52 0.153 0
GIN1 GIN1 Q9NXP7 Gypsy retrotransposon integrase-like protein 1 chr5 GO:0090304 Not Cancer Driver No 66 0.126 87 12 0.138 0
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0090304 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0090304 Not Cancer Driver No 36 0.167 14 0 0.0 0
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0090304 Not Cancer Driver No 12 0.073 10 1 0.1 0
GPAT2_ENST00000359548 GPAT2 Q6NUI2 Glycerol-3-phosphate acyltransferase 2, mitochondrial chr2 GO:0090304 Not Cancer Driver No 75 0.094 34 6 0.176 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0090304 Not Cancer Driver No 33 0.104 80 6 0.075 0
GTF2H5 GTF2H5 Q6ZYL4 General transcription factor IIH subunit 5 chr6 GO:0090304 Not Cancer Driver No 7 0.099 0 0 0.0 1
GTF2I GTF2I P78347 General transcription factor II-I chr7 GO:0090304 Compendium Yes 74 0.074 365 27 0.074 0
GTF3A GTF3A Q92664 Transcription factor IIIA chr13 GO:0090304 Not Cancer Driver No 20 0.055 73 7 0.096 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 GO:0090304 Not Cancer Driver No 323 0.153 735 114 0.155 0
GTF3C2 GTF3C2 Q8WUA4 General transcription factor 3C polypeptide 2 chr2 GO:0090304 Not Cancer Driver No 111 0.122 394 45 0.114 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 GO:0090304 Not Cancer Driver No 109 0.123 195 22 0.113 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 GO:0090304 Not Cancer Driver No 76 0.092 164 13 0.079 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 GO:0090304 Not Cancer Driver No 75 0.145 157 21 0.134 0
GTF3C6 GTF3C6 Q969F1 General transcription factor 3C polypeptide 6 chr6 GO:0090304 Not Cancer Driver No 19 0.089 130 11 0.085 0
HARS2_ENST00000642231 HARS2 P49590 Histidine--tRNA ligase, mitochondrial chr5 GO:0090304 Not Cancer Driver No 48 0.095 34 4 0.118 2
HARS_ENST00000644191 HARS1 P12081 Histidine--tRNA ligase, cytoplasmic chr5 GO:0090304 Not Cancer Driver No 65 0.128 17 2 0.118 7
HELB HELB Q8NG08 DNA helicase B chr12 GO:0090304 Not Cancer Driver No 140 0.129 300 38 0.127 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0090304 Not Cancer Driver No 78 0.093 227 25 0.11 0
HEMK1_ENST00000455834 HEMK1 Q9Y5R4 MTRF1L release factor glutamine methyltransferase chr3 GO:0090304 Not Cancer Driver No 36 0.107 14 0 0.0 0
HENMT1 HENMT1 Q5T8I9 Small RNA 2'-O-methyltransferase chr1 GO:0090304 Not Cancer Driver No 55 0.14 32 6 0.188 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0090304 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0090304 Not Cancer Driver No 21 0.162 61 10 0.164 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0090304 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0090304 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0090304 Not Cancer Driver No 38 0.182 207 38 0.184 0
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0090304 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0090304 Not Cancer Driver No 31 0.093 202 11 0.054 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0090304 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0090304 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:0090304 Not Cancer Driver No 52 0.156 23 3 0.13 1
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0090304 Not Cancer Driver No 61 0.106 82 6 0.073 2
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0090304 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0090304 Not Cancer Driver No 149 0.147 145 22 0.152 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0090304 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0090304 Not Cancer Driver No 107 0.109 399 45 0.113 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0090304 Compendium Yes 173 0.111 682 76 0.111 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 GO:0090304 Not Cancer Driver No 234 0.107 368 43 0.117 1
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0090304 Not Cancer Driver No 20 0.11 6 0 0.0 0
ISG20L2 ISG20L2 Q9H9L3 Interferon-stimulated 20 kDa exonuclease-like 2 chr1 GO:0090304 Not Cancer Driver No 46 0.13 232 33 0.142 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0090304 Not Cancer Driver No 51 0.127 133 21 0.158 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0090304 Not Cancer Driver No 88 0.147 160 15 0.094 12
KDM1B_ENST00000449850 KDM1B Q8NB78 Lysine-specific histone demethylase 1B chr6 GO:0090304 Not Cancer Driver No 81 0.099 74 11 0.149 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0090304 Not Cancer Driver No 84 0.118 684 81 0.118 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0090304 Not Cancer Driver No 62 0.106 60 12 0.2 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0090304 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KRBA2_ENST00000331336 KRBA2 Q6ZNG9 KRAB-A domain-containing protein 2 chr17 GO:0090304 Not Cancer Driver No 56 0.114 150 18 0.12 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0090304 Not Cancer Driver No 58 0.1 350 44 0.126 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0090304 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0090304 Not Cancer Driver No 74 0.082 80 8 0.1 3
LCMT2 LCMT2 O60294 tRNA wybutosine-synthesizing protein 4 chr15 GO:0090304 Not Cancer Driver No 101 0.147 33 2 0.061 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0090304 Census Yes 64 0.16 370 57 0.154 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 GO:0090304 Not Cancer Driver No 137 0.149 397 62 0.156 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0090304 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0090304 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0090304 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0090304 Not Cancer Driver No 60 0.24 179 32 0.179 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0090304 Not Cancer Driver No 99 0.103 175 15 0.086 10
LRRC47 LRRC47 Q8N1G4 Leucine-rich repeat-containing protein 47 chr1 GO:0090304 Not Cancer Driver No 65 0.111 291 30 0.103 0
LSM1 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 GO:0090304 Not Cancer Driver No 21 0.158 6 1 0.167 0
LSM10 LSM10 Q969L4 U7 snRNA-associated Sm-like protein LSm10 chr1 GO:0090304 Not Cancer Driver No 21 0.171 12 5 0.417 0
LSM11 LSM11 P83369 U7 snRNA-associated Sm-like protein LSm11 chr5 GO:0090304 Not Cancer Driver No 34 0.094 266 17 0.064 1
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0090304 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 GO:0090304 Not Cancer Driver No 126 0.29 114 35 0.307 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0090304 Not Cancer Driver No 91 0.101 151 16 0.106 8
MARS2 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 GO:0090304 Not Cancer Driver No 75 0.126 34 6 0.176 1
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0090304 Not Cancer Driver No 46 0.096 249 22 0.088 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0090304 Not Cancer Driver No 61 0.105 268 27 0.101 0
MBLAC1 MBLAC1 A4D2B0 Metallo-beta-lactamase domain-containing protein 1 chr7 GO:0090304 Not Cancer Driver No 26 0.098 175 22 0.126 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0090304 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0090304 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 GO:0090304 Not Cancer Driver No 92 0.114 310 47 0.152 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 GO:0090304 Not Cancer Driver No 121 0.14 215 35 0.163 0
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0090304 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0090304 Not Cancer Driver No 56 0.049 523 13 0.025 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0090304 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MED18_ENST00000398997 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 GO:0090304 Not Cancer Driver No 35 0.168 10 2 0.2 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0090304 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL1 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 GO:0090304 Not Cancer Driver No 43 0.156 89 11 0.124 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0090304 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0090304 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0090304 Not Cancer Driver No 74 0.128 274 29 0.106 0
METTL4 METTL4 Q8N3J2 N(6)-adenine-specific methyltransferase METTL4 chr18 GO:0090304 Not Cancer Driver No 61 0.129 34 4 0.118 0
METTL8_ENST00000638989 METTL8 Q9H825 tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial chr2 GO:0090304 Not Cancer Driver No 32 0.11 95 11 0.116 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0090304 Not Cancer Driver No 33 0.096 95 7 0.074 1
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0090304 Census Yes 92 0.122 208 22 0.106 85
MOCS3 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 GO:0090304 Not Cancer Driver No 61 0.133 15 5 0.333 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0090304 Not Cancer Driver No 300 0.305 252 77 0.306 0
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:0090304 Not Cancer Driver No 184 0.152 178 21 0.118 0
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 GO:0090304 Not Cancer Driver No 35 0.117 141 21 0.149 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0090304 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRM2_ENST00000440306 MRM2 Q9UI43 rRNA methyltransferase 2, mitochondrial chr7 GO:0090304 Not Cancer Driver No 37 0.15 15 1 0.067 1
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 GO:0090304 Not Cancer Driver No 45 0.107 83 8 0.096 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0090304 Not Cancer Driver No 37 0.111 45 2 0.044 1
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0090304 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0090304 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0090304 Census Yes 154 0.113 386 41 0.106 6
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 GO:0090304 Not Cancer Driver No 78 0.117 283 32 0.113 0
MTERF1 MTERF1 Q99551 Transcription termination factor 1, mitochondrial chr7 GO:0090304 Not Cancer Driver No 48 0.12 0 0 0.0 0
MTERF2 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 GO:0090304 Not Cancer Driver No 49 0.127 0 0 0.0 0
MTFMT MTFMT Q96DP5 Methionyl-tRNA formyltransferase, mitochondrial chr15 GO:0090304 Not Cancer Driver No 35 0.09 56 3 0.054 3
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 GO:0090304 Not Cancer Driver No 70 0.098 61 2 0.033 1
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0090304 Not Cancer Driver No 73 0.125 136 22 0.162 1
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0090304 Not Cancer Driver No 117 0.112 160 15 0.094 0
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0090304 Not Cancer Driver No 101 0.145 84 13 0.155 5
MUTYH MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0090304 Census Yes 90 0.165 198 29 0.146 23
MYBL1 MYBL1 P10243 Myb-related protein A chr8 GO:0090304 Not Cancer Driver No 78 0.104 501 58 0.116 0
N6AMT1 N6AMT1 Q9Y5N5 Methyltransferase N6AMT1 chr21 GO:0090304 Not Cancer Driver No 44 0.206 20 3 0.15 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0090304 Not Cancer Driver No 61 0.123 386 44 0.114 0
NARS NARS1 O43776 Asparagine--tRNA ligase, cytoplasmic chr18 GO:0090304 Not Cancer Driver No 50 0.091 103 16 0.155 4
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 GO:0090304 Not Cancer Driver No 79 0.166 22 2 0.091 3
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0090304 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBN NBN O60934 Nibrin chr8 GO:0090304 Census Yes 90 0.119 417 54 0.129 1
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0090304 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCBP3 NCBP3 Q53F19 Nuclear cap-binding protein subunit 3 chr17 GO:0090304 Not Cancer Driver No 52 0.084 507 42 0.083 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0090304 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0090304 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0090304 Not Cancer Driver No 31 0.093 145 14 0.097 0
NEIL3 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 GO:0090304 Not Cancer Driver No 80 0.132 131 18 0.137 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0090304 Not Cancer Driver No 35 0.117 83 8 0.096 2
NHP2 NHP2 Q9NX24 H/ACA ribonucleoprotein complex subunit 2 chr5 GO:0090304 Not Cancer Driver No 26 0.17 20 4 0.2 2
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 GO:0090304 Not Cancer Driver No 32 0.109 148 15 0.101 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0090304 Compendium Yes 353 0.126 1528 184 0.12 37
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0090304 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 GO:0090304 Not Cancer Driver No 73 0.104 102 8 0.078 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:0090304 Not Cancer Driver No 74 0.106 662 69 0.104 0
NOP10 NOP10 Q9NPE3 H/ACA ribonucleoprotein complex subunit 3 chr15 GO:0090304 Not Cancer Driver No 12 0.188 20 2 0.1 1
NOP14 NOP14 P78316 Nucleolar protein 14 chr4 GO:0090304 Not Cancer Driver No 87 0.102 521 46 0.088 0
NOP9 NOP9 Q86U38 Nucleolar protein 9 chr14 GO:0090304 Not Cancer Driver No 53 0.083 166 14 0.084 0
NPM3 NPM3 O75607 Nucleoplasmin-3 chr10 GO:0090304 Not Cancer Driver No 23 0.129 78 11 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0090304 Not Cancer Driver No 56 0.125 146 13 0.089 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0090304 Not Cancer Driver No 30 0.121 119 12 0.101 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:0090304 Not Cancer Driver No 112 0.146 221 21 0.095 1
NSUN3 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 GO:0090304 Not Cancer Driver No 34 0.1 0 0 0.0 0
NSUN6 NSUN6 Q8TEA1 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 chr10 GO:0090304 Not Cancer Driver No 68 0.145 50 10 0.2 0
NT5C3B NT5C3B Q969T7 7-methylguanosine phosphate-specific 5'-nucleotidase chr17 GO:0090304 Not Cancer Driver No 25 0.083 2 0 0.0 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0090304 Census Yes 38 0.122 147 18 0.122 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0090304 Not Cancer Driver No 30 0.123 243 30 0.123 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0090304 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0090304 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0090304 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0090304 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0090304 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0090304 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0090304 Not Cancer Driver No 22 0.128 38 5 0.132 0
NYNRIN NYNRIN Q9P2P1 Protein NYNRIN chr14 GO:0090304 Not Cancer Driver No 250 0.132 636 70 0.11 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0090304 Not Cancer Driver No 37 0.107 71 12 0.169 0
OSGEP OSGEP Q9NPF4 tRNA N6-adenosine threonylcarbamoyltransferase chr14 GO:0090304 Not Cancer Driver No 46 0.137 32 4 0.125 14
OSGEPL1_ENST00000522700 OSGEPL1 Q9H4B0 tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial chr2 GO:0090304 Not Cancer Driver No 43 0.104 1 0 0.0 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0090304 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0090304 Not Cancer Driver No 104 0.117 323 35 0.108 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 GO:0090304 Not Cancer Driver No 97 0.13 293 28 0.096 0
PAPOLG PAPOLG Q9BWT3 Poly(A) polymerase gamma chr2 GO:0090304 Not Cancer Driver No 94 0.128 303 35 0.116 0
PARG_ENST00000616448 PARG Q86W56 Poly(ADP-ribose) glycohydrolase chr10 GO:0090304 Not Cancer Driver No 60 0.061 519 1 0.002 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0090304 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0090304 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0090304 Not Cancer Driver No 74 0.127 172 23 0.134 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0090304 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARS2 PARS2 Q7L3T8 Probable proline--tRNA ligase, mitochondrial chr1 GO:0090304 Not Cancer Driver No 50 0.105 8 2 0.25 0
PCF11 PCF11 O94913 Pre-mRNA cleavage complex 2 protein Pcf11 chr11 GO:0090304 Not Cancer Driver No 211 0.136 1250 189 0.151 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0090304 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCIF1 PCIF1 Q9H4Z3 mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase chr20 GO:0090304 Not Cancer Driver No 77 0.109 288 37 0.128 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0090304 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0090304 Not Cancer Driver No 59 0.097 129 8 0.062 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0090304 Not Cancer Driver No 38 0.099 67 10 0.149 0
PGBD5 PGBD5 Q8N414 PiggyBac transposable element-derived protein 5 chr1 GO:0090304 Not Cancer Driver No 73 0.139 126 1 0.008 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0090304 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIWIL1 PIWIL1 Q96J94 Piwi-like protein 1 chr12 GO:0090304 Not Cancer Driver No 202 0.235 172 37 0.215 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0090304 Not Cancer Driver No 138 0.142 232 38 0.164 0
PIWIL4 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 GO:0090304 Not Cancer Driver No 115 0.135 89 11 0.124 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0090304 Not Cancer Driver No 27 0.107 24 6 0.25 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0090304 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLDC1_ENST00000610273 PNLDC1 Q8NA58 Poly(A)-specific ribonuclease PNLDC1 chr6 GO:0090304 Not Cancer Driver No 105 0.202 6 0 0.0 1
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0090304 Not Cancer Driver No 86 0.11 115 10 0.087 2
PNRC2_ENST00000374468 PNRC2 Q9NPJ4 Proline-rich nuclear receptor coactivator 2 chr1 GO:0090304 Not Cancer Driver No 1 0.007 122 1 0.008 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:0090304 Not Cancer Driver No 185 0.127 347 45 0.13 3
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 GO:0090304 Not Cancer Driver No 63 0.105 102 16 0.157 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0090304 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0090304 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0090304 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0090304 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0090304 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0090304 Census, Compendium Yes 409 0.179 239 44 0.184 3
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0090304 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 GO:0090304 Not Cancer Driver No 11 0.075 117 9 0.077 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0090304 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLG_ENST00000442287 POLG P54098 DNA polymerase subunit gamma-1 chr15 GO:0090304 Census Yes 139 0.112 421 42 0.1 73
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0090304 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0090304 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0090304 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLL_ENST00000370169 POLL Q9UGP5 DNA polymerase lambda chr10 GO:0090304 Not Cancer Driver No 69 0.12 215 16 0.074 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0090304 Census, Compendium Yes 364 0.141 949 135 0.142 0
POLR1B_ENST00000263331 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 GO:0090304 Not Cancer Driver No 120 0.106 69 10 0.145 2
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 GO:0090304 Not Cancer Driver No 39 0.093 85 6 0.071 0
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0090304 Not Cancer Driver No 15 0.087 15 1 0.067 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0090304 Not Cancer Driver No 21 0.168 22 5 0.227 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 GO:0090304 Not Cancer Driver No 10 0.149 0 0 0.0 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 GO:0090304 Not Cancer Driver No 23 0.113 33 6 0.182 0
POLR3K POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 GO:0090304 Not Cancer Driver No 10 0.093 0 0 0.0 1
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0090304 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:0090304 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:0090304 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:0090304 Not Cancer Driver No 20 0.143 59 13 0.22 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0090304 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0090304 Census Yes 72 0.143 44 4 0.091 3
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0090304 Census, Compendium Yes 54 0.089 370 32 0.086 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0090304 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRIM1 PRIM1 P49642 DNA primase small subunit chr12 GO:0090304 Not Cancer Driver No 31 0.074 22 1 0.045 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0090304 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0090304 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0090304 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0090304 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0090304 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRMT7_ENST00000441236 PRMT7 Q9NVM4 Protein arginine N-methyltransferase 7 chr16 GO:0090304 Not Cancer Driver No 71 0.103 39 1 0.026 3
PRPF18 PRPF18 Q99633 Pre-mRNA-splicing factor 18 chr10 GO:0090304 Not Cancer Driver No 52 0.152 93 18 0.194 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0090304 Census, Compendium Yes 69 0.282 205 49 0.239 1
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0090304 Not Cancer Driver No 25 0.115 73 8 0.11 0
PSTK PSTK Q8IV42 L-seryl-tRNA(Sec) kinase chr10 GO:0090304 Not Cancer Driver No 48 0.138 79 15 0.19 0
PTCD1 PTCD1 O75127 Pentatricopeptide repeat-containing protein 1, mitochondrial chr7 GO:0090304 Not Cancer Driver No 99 0.141 224 42 0.188 0
PUS1 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 GO:0090304 Not Cancer Driver No 48 0.112 157 18 0.115 1
PUS10_ENST00000407787 PUS10 Q3MIT2 tRNA pseudouridine synthase Pus10 chr2 GO:0090304 Not Cancer Driver No 59 0.112 43 5 0.116 0
PUS3_ENST00000530811 PUS3 Q9BZE2 tRNA pseudouridine(38/39) synthase chr11 GO:0090304 Not Cancer Driver No 55 0.114 150 15 0.1 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 GO:0090304 Not Cancer Driver No 73 0.11 162 17 0.105 1
PUSL1 PUSL1 Q8N0Z8 tRNA pseudouridine synthase-like 1 chr1 GO:0090304 Not Cancer Driver No 15 0.05 76 1 0.013 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0090304 Not Cancer Driver No 101 0.13 106 16 0.151 4
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 GO:0090304 Not Cancer Driver No 63 0.119 63 4 0.063 2
QTRT1 QTRT1 Q9BXR0 Queuine tRNA-ribosyltransferase catalytic subunit 1 chr19 GO:0090304 Not Cancer Driver No 55 0.136 36 9 0.25 0
QTRT2_ENST00000281273 QTRT2 Q9H974 Queuine tRNA-ribosyltransferase accessory subunit 2 chr3 GO:0090304 Not Cancer Driver No 51 0.123 30 6 0.2 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0090304 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0090304 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0090304 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0090304 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0090304 Not Cancer Driver No 34 0.104 49 10 0.204 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0090304 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0090304 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0090304 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAMAC RAMAC Q9BTL3 RNA guanine-N7 methyltransferase activating subunit chr15 GO:0090304 Not Cancer Driver No 14 0.119 118 14 0.119 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0090304 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 GO:0090304 Not Cancer Driver No 72 0.109 41 3 0.073 2
RARS2 RARS2 Q5T160 Probable arginine--tRNA ligase, mitochondrial chr6 GO:0090304 Not Cancer Driver No 88 0.152 20 1 0.05 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0090304 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBM47_ENST00000295971 RBM47 A0AV96 RNA-binding protein 47 chr4 GO:0090304 Not Cancer Driver No 143 0.241 131 28 0.214 0
RBM7_ENST00000540163 RBM7 Q9Y580 RNA-binding protein 7 chr11 GO:0090304 Not Cancer Driver No 36 0.135 194 27 0.139 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0090304 Not Cancer Driver No 33 0.126 23 0 0.0 0
RCL1 RCL1 Q9Y2P8 RNA 3'-terminal phosphate cyclase-like protein chr9 GO:0090304 Not Cancer Driver No 40 0.107 12 0 0.0 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0090304 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0090304 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0090304 Not Cancer Driver No 132 0.133 495 71 0.143 0
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0090304 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0090304 Not Cancer Driver No 379 0.121 1665 211 0.127 0
REXO2 REXO2 Q9Y3B8 Oligoribonuclease, mitochondrial chr11 GO:0090304 Not Cancer Driver No 19 0.08 43 4 0.093 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0090304 Not Cancer Driver No 34 0.081 298 26 0.087 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0090304 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RMI1 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 GO:0090304 Not Cancer Driver No 67 0.107 243 26 0.107 0
RMI2 RMI2 Q96E14 RecQ-mediated genome instability protein 2 chr16 GO:0090304 Census Yes 12 0.082 86 5 0.058 0
RNASE4_ENST00000555597 RNASE4 P34096 Ribonuclease 4 chr14 GO:0090304 Not Cancer Driver No 24 0.163 9 2 0.222 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0090304 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0090304 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0090304 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF113A RNF113A O15541 E3 ubiquitin-protein ligase RNF113A chrX GO:0090304 Not Cancer Driver No 61 0.178 226 51 0.226 0
RNF113B RNF113B Q8IZP6 RING finger protein 113B chr13 GO:0090304 Not Cancer Driver No 56 0.174 170 34 0.2 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 GO:0090304 Not Cancer Driver No 44 0.18 34 6 0.176 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0090304 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF212 RNF212 Q495C1 Probable E3 SUMO-protein ligase RNF212 chr4 GO:0090304 Not Cancer Driver No 36 0.121 58 12 0.207 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0090304 Not Cancer Driver No 56 0.115 226 29 0.128 0
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 GO:0090304 Not Cancer Driver No 69 0.116 112 12 0.107 0
RNMT_ENST00000543302 RNMT O43148 mRNA cap guanine-N7 methyltransferase chr18 GO:0090304 Not Cancer Driver No 67 0.141 159 23 0.145 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0090304 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:0090304 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:0090304 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:0090304 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP25L RPP25L Q8N5L8 Ribonuclease P protein subunit p25-like protein chr9 GO:0090304 Not Cancer Driver No 31 0.19 113 18 0.159 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:0090304 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:0090304 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:0090304 Not Cancer Driver No 51 0.14 5 0 0.0 0
RPS21 RPS21 P63220 40S ribosomal protein S21 chr20 GO:0090304 Not Cancer Driver No 8 0.096 0 0 0.0 0
RPUSD1_ENST00000007264 RPUSD1 Q9UJJ7 RNA pseudouridylate synthase domain-containing protein 1 chr16 GO:0090304 Not Cancer Driver No 30 0.096 88 3 0.034 0
RPUSD2 RPUSD2 Q8IZ73 Pseudouridylate synthase RPUSD2 chr15 GO:0090304 Not Cancer Driver No 49 0.09 231 22 0.095 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0090304 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0090304 Not Cancer Driver No 54 0.143 97 15 0.155 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0090304 Not Cancer Driver No 66 0.101 115 15 0.13 0
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 GO:0090304 Not Cancer Driver No 57 0.113 74 7 0.095 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0090304 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 GO:0090304 Not Cancer Driver No 44 0.144 170 22 0.129 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0090304 Compendium Yes 90 0.195 184 26 0.141 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0090304 Not Cancer Driver No 104 0.166 91 14 0.154 13
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 GO:0090304 Not Cancer Driver No 64 0.124 111 14 0.126 1
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0090304 Not Cancer Driver No 56 0.109 83 4 0.048 1
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0090304 Not Cancer Driver No 71 0.089 685 63 0.092 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0090304 Not Cancer Driver No 155 0.122 939 118 0.126 0
SEPSECS SEPSECS Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase chr4 GO:0090304 Not Cancer Driver No 47 0.094 22 7 0.318 3
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0090304 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0090304 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0090304 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0090304 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0090304 Not Cancer Driver No 48 0.12 163 15 0.092 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0090304 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLBP SLBP Q14493 Histone RNA hairpin-binding protein chr4 GO:0090304 Not Cancer Driver No 21 0.078 236 17 0.072 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0090304 Not Cancer Driver No 177 0.196 34 8 0.235 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0090304 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0090304 Not Cancer Driver No 66 0.072 61 3 0.049 4
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0090304 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0090304 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0090304 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0090304 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0090304 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0090304 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0090304 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0090304 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0090304 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMN2_ENST00000380741 SMN2 Q16637 Survival motor neuron protein chr5 GO:0090304 Not Cancer Driver No 1 0.003 220 1 0.005 18
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0090304 Not Cancer Driver No 33 0.122 46 2 0.043 0
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 GO:0090304 Not Cancer Driver No 36 0.098 158 16 0.101 0
SNAPC2 SNAPC2 Q13487 snRNA-activating protein complex subunit 2 chr19 GO:0090304 Not Cancer Driver No 33 0.099 260 24 0.092 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0090304 Not Cancer Driver No 30 0.073 99 2 0.02 0
SNAPC4 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 GO:0090304 Not Cancer Driver No 143 0.097 1094 96 0.088 0
SNAPC5_ENST00000395589 SNAPC5 O75971 snRNA-activating protein complex subunit 5 chr15 GO:0090304 Not Cancer Driver No 9 0.092 95 9 0.095 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0090304 Census Yes 127 0.14 258 48 0.186 0
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 GO:0090304 Not Cancer Driver No 71 0.196 220 40 0.182 0
SPIN1 SPIN1 Q9Y657 Spindlin-1 chr9 GO:0090304 Not Cancer Driver No 31 0.118 132 18 0.136 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0090304 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPOCD1 SPOCD1 Q6ZMY3 SPOC domain-containing protein 1 chr1 GO:0090304 Not Cancer Driver No 158 0.13 877 113 0.129 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0090304 Not Cancer Driver No 73 0.149 252 38 0.151 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0090304 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0090304 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRRT SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 GO:0090304 Not Cancer Driver No 146 0.167 595 108 0.182 0
SSB SSB P05455 Lupus La protein chr2 GO:0090304 Not Cancer Driver No 39 0.096 181 18 0.099 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0090304 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0090304 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0090304 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0090304 Not Cancer Driver No 8 0.041 8 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0090304 Census, Compendium Yes 110 0.143 152 15 0.099 19
STPG4 STPG4 Q8N801 Protein STPG4 chr2 GO:0090304 Not Cancer Driver No 32 0.129 132 17 0.129 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 GO:0090304 Not Cancer Driver No 13 0.102 108 6 0.056 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0090304 Not Cancer Driver No 222 0.129 761 107 0.141 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0090304 Not Cancer Driver No 72 0.092 140 12 0.086 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0090304 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0090304 Not Cancer Driver No 207 0.212 602 124 0.206 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0090304 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF11 TAF11 Q15544 Transcription initiation factor TFIID subunit 11 chr6 GO:0090304 Not Cancer Driver No 22 0.104 137 16 0.117 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:0090304 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF13 TAF13 Q15543 Transcription initiation factor TFIID subunit 13 chr1 GO:0090304 Not Cancer Driver No 11 0.089 34 3 0.088 2
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0090304 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0090304 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0090304 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF3 TAF3 Q5VWG9 Transcription initiation factor TFIID subunit 3 chr10 GO:0090304 Not Cancer Driver No 113 0.122 750 90 0.12 0
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0090304 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF4B_ENST00000269142 TAF4B Q92750 Transcription initiation factor TFIID subunit 4B chr18 GO:0090304 Not Cancer Driver No 86 0.1 482 46 0.095 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:0090304 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0090304 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0090304 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0090304 Not Cancer Driver No 35 0.113 255 30 0.118 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0090304 Not Cancer Driver No 25 0.095 203 19 0.094 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0090304 Not Cancer Driver No 45 0.123 203 22 0.108 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0090304 Not Cancer Driver No 112 0.156 53 10 0.189 1
TARSL2 TARS3 A2RTX5 Threonine--tRNA ligase 2, cytoplasmic chr15 GO:0090304 Not Cancer Driver No 90 0.112 77 14 0.182 0
TARS_ENST00000265112 TARS1 P26639 Threonine--tRNA ligase 1, cytoplasmic chr5 GO:0090304 Not Cancer Driver No 112 0.155 112 22 0.196 2
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 GO:0090304 Not Cancer Driver No 82 0.101 48 8 0.167 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0090304 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 GO:0090304 Not Cancer Driver No 74 0.117 60 2 0.033 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0090304 Census Yes 52 0.08 649 52 0.08 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0090304 Census, Compendium Yes 122 0.197 516 93 0.18 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0090304 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0090304 Not Cancer Driver No 81 0.133 179 25 0.14 1
TDRD1 TDRD1 Q9BXT4 Tudor domain-containing protein 1 chr10 GO:0090304 Not Cancer Driver No 200 0.169 216 27 0.125 0
TDRD10 TDRD10 Q5VZ19 Tudor domain-containing protein 10 chr1 GO:0090304 Not Cancer Driver No 85 0.232 31 6 0.194 0
TDRD12_ENST00000444215 TDRD12 Q587J7 Putative ATP-dependent RNA helicase TDRD12 chr19 GO:0090304 Not Cancer Driver No 36 0.031 220 10 0.045 0
TDRD15_ENST00000622654 TDRD15 B5MCY1 Tudor domain-containing protein 15 chr2 GO:0090304 Not Cancer Driver No 8 0.004 99 1 0.01 0
TDRD5_ENST00000294848 TDRD5 Q8NAT2 Tudor domain-containing protein 5 chr1 GO:0090304 Not Cancer Driver No 231 0.235 343 74 0.216 0
TDRD6 TDRD6 O60522 Tudor domain-containing protein 6 chr6 GO:0090304 Not Cancer Driver No 290 0.138 455 50 0.11 0
TDRD7 TDRD7 Q8NHU6 Tudor domain-containing protein 7 chr9 GO:0090304 Not Cancer Driver No 126 0.115 266 38 0.143 0
TDRD9 TDRD9 Q8NDG6 ATP-dependent RNA helicase TDRD9 chr14 GO:0090304 Not Cancer Driver No 156 0.113 108 0 0.0 0
TDRKH_ENST00000368827 TDRKH Q9Y2W6 Tudor and KH domain-containing protein chr1 GO:0090304 Not Cancer Driver No 76 0.135 185 27 0.146 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0090304 Not Cancer Driver No 37 0.103 26 5 0.192 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0090304 Not Cancer Driver No 65 0.134 75 15 0.2 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0090304 Not Cancer Driver No 106 0.137 442 43 0.097 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 GO:0090304 Not Cancer Driver No 332 0.126 396 67 0.169 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0090304 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0090304 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0090304 Not Cancer Driver No 28 0.07 310 16 0.052 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0090304 Census Yes 110 0.097 212 16 0.075 31
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0090304 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0090304 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 GO:0090304 Not Cancer Driver No 208 0.116 1272 152 0.119 6
TEX11_ENST00000344304 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:0090304 Not Cancer Driver No 139 0.148 30 3 0.1 2
TEX12 TEX12 Q9BXU0 Testis-expressed protein 12 chr11 GO:0090304 Not Cancer Driver No 10 0.081 35 3 0.086 0
TEX15_ENST00000256246 TEX15 Q9BXT5 Testis-expressed protein 15 chr8 GO:0090304 Not Cancer Driver No 479 0.172 1258 223 0.177 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 GO:0090304 Not Cancer Driver No 40 0.128 107 11 0.103 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0090304 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFB1M TFB1M Q8WVM0 Dimethyladenosine transferase 1, mitochondrial chr6 GO:0090304 Not Cancer Driver No 50 0.145 26 3 0.115 0
TFB2M TFB2M Q9H5Q4 Dimethyladenosine transferase 2, mitochondrial chr1 GO:0090304 Not Cancer Driver No 60 0.152 36 6 0.167 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 GO:0090304 Not Cancer Driver No 68 0.135 169 23 0.136 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0090304 Not Cancer Driver No 87 0.104 331 39 0.118 0
TGS1 TGS1 Q96RS0 Trimethylguanosine synthase chr8 GO:0090304 Not Cancer Driver No 100 0.117 483 56 0.116 0
THAP9 THAP9 Q9H5L6 DNA transposase THAP9 chr4 GO:0090304 Not Cancer Driver No 82 0.091 46 6 0.13 0
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0090304 Not Cancer Driver No 32 0.107 22 2 0.091 1
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0090304 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0090304 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIPIN TIPIN Q9BVW5 TIMELESS-interacting protein chr15 GO:0090304 Not Cancer Driver No 26 0.086 242 19 0.079 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0090304 Not Cancer Driver No 21 0.382 55 21 0.382 0
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 GO:0090304 Not Cancer Driver No 44 0.086 210 22 0.105 10
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0090304 Census, Compendium Yes 93 0.122 391 53 0.136 0
TOP1MT TOP1MT Q969P6 DNA topoisomerase I, mitochondrial chr8 GO:0090304 Not Cancer Driver No 102 0.17 171 32 0.187 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0090304 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0090304 Not Cancer Driver No 154 0.095 543 46 0.085 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 GO:0090304 Not Cancer Driver No 103 0.103 293 31 0.106 2
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 GO:0090304 Not Cancer Driver No 102 0.118 151 17 0.113 0
TOPAZ1 TOPAZ1 Q8N9V7 Protein TOPAZ1 chr3 GO:0090304 Not Cancer Driver No 110 0.065 814 61 0.075 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0090304 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPRKB_ENST00000272424 TPRKB Q9Y3C4 EKC/KEOPS complex subunit TPRKB chr2 GO:0090304 Not Cancer Driver No 20 0.114 0 0 0.0 2
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0090304 Not Cancer Driver No 63 0.134 240 33 0.138 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0090304 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0090304 Not Cancer Driver No 33 0.14 23 6 0.261 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0090304 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0090304 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRIR TRIR Q9BQ61 Telomerase RNA component interacting RNase chr19 GO:0090304 Not Cancer Driver No 17 0.097 176 17 0.097 0
TRIT1 TRIT1 Q9H3H1 tRNA dimethylallyltransferase chr1 GO:0090304 Not Cancer Driver No 61 0.131 121 19 0.157 1
TRMT10A_ENST00000394876 TRMT10A Q8TBZ6 tRNA methyltransferase 10 homolog A chr4 GO:0090304 Not Cancer Driver No 49 0.145 182 28 0.154 1
TRMT10B TRMT10B Q6PF06 tRNA methyltransferase 10 homolog B chr9 GO:0090304 Not Cancer Driver No 35 0.111 75 13 0.173 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0090304 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 GO:0090304 Not Cancer Driver No 15 0.12 17 2 0.118 0
TRMT1L TRMT1L Q7Z2T5 TRMT1-like protein chr1 GO:0090304 Not Cancer Driver No 71 0.097 241 19 0.079 0
TRMT1_ENST00000357720 TRMT1 Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase chr19 GO:0090304 Not Cancer Driver No 82 0.124 200 24 0.12 0
TRMT5 TRMT5 Q32P41 tRNA (guanine(37)-N1)-methyltransferase chr14 GO:0090304 Not Cancer Driver No 46 0.09 67 5 0.075 2
TRMT6 TRMT6 Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 chr20 GO:0090304 Not Cancer Driver No 42 0.085 208 17 0.082 0
TRMT61A TRMT61A Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A chr14 GO:0090304 Not Cancer Driver No 16 0.055 74 9 0.122 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 GO:0090304 Not Cancer Driver No 48 0.101 123 10 0.081 0
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 GO:0090304 Not Cancer Driver No 40 0.095 28 5 0.179 2
TRNT1 TRNT1 Q96Q11 CCA tRNA nucleotidyltransferase 1, mitochondrial chr3 GO:0090304 Not Cancer Driver No 60 0.138 49 8 0.163 7
TRUB1 TRUB1 Q8WWH5 Pseudouridylate synthase TRUB1 chr10 GO:0090304 Not Cancer Driver No 42 0.12 120 15 0.125 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0090304 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:0090304 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:0090304 Not Cancer Driver No 40 0.129 176 22 0.125 1
TSEN54 TSEN54 Q7Z6J9 tRNA-splicing endonuclease subunit Sen54 chr17 GO:0090304 Not Cancer Driver No 44 0.084 279 29 0.104 4
TSN TSN Q15631 Translin chr2 GO:0090304 Not Cancer Driver No 30 0.132 0 0 0.0 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 GO:0090304 Not Cancer Driver No 23 0.079 68 3 0.044 0
TSR3 TSR3 Q9UJK0 18S rRNA aminocarboxypropyltransferase chr16 GO:0090304 Not Cancer Driver No 31 0.099 144 13 0.09 0
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 GO:0090304 Not Cancer Driver No 164 0.105 59 3 0.051 3
TTF1 TTF1 Q15361 Transcription termination factor 1 chr9 GO:0090304 Not Cancer Driver No 105 0.116 535 59 0.11 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0090304 Not Cancer Driver No 118 0.102 550 50 0.091 0
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0090304 Not Cancer Driver No 97 0.111 410 50 0.122 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0090304 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0090304 Not Cancer Driver No 159 0.106 659 74 0.112 0
TYW1 TYW1 Q9NV66 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 chr7 GO:0090304 Not Cancer Driver No 102 0.139 152 21 0.138 0
TYW1B TYW1B Q6NUM6 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B chr7 GO:0090304 Not Cancer Driver No 108 0.162 161 28 0.174 0
TYW5 TYW5 A2RUC4 tRNA wybutosine-synthesizing protein 5 chr2 GO:0090304 Not Cancer Driver No 32 0.102 11 1 0.091 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0090304 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0090304 Not Cancer Driver No 100 0.131 567 77 0.136 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0090304 Not Cancer Driver No 97 0.122 353 49 0.139 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 GO:0090304 Not Cancer Driver No 88 0.11 253 22 0.087 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0090304 Not Cancer Driver No 34 0.109 96 13 0.135 1
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0090304 Not Cancer Driver No 146 0.129 329 36 0.109 0
URM1_ENST00000372853 URM1 Q9BTM9 Ubiquitin-related modifier 1 chr9 GO:0090304 Not Cancer Driver No 7 0.069 0 0 0.0 0
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 GO:0090304 Not Cancer Driver No 28 0.106 76 5 0.066 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0090304 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0090304 Not Cancer Driver No 170 0.154 215 45 0.209 0
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0090304 Not Cancer Driver No 107 0.098 578 55 0.095 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 GO:0090304 Not Cancer Driver No 324 0.116 314 35 0.111 0
UTP23 UTP23 Q9BRU9 rRNA-processing protein UTP23 homolog chr8 GO:0090304 Not Cancer Driver No 35 0.141 97 16 0.165 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0090304 Not Cancer Driver No 89 0.127 243 28 0.115 0
UVSSA UVSSA Q2YD98 UV-stimulated scaffold protein A chr4 GO:0090304 Not Cancer Driver No 101 0.142 519 70 0.135 1
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0090304 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0090304 Not Cancer Driver No 111 0.104 253 21 0.083 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0090304 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0090304 Not Cancer Driver No 133 0.109 543 61 0.112 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0090304 Not Cancer Driver No 64 0.15 102 16 0.157 14
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 GO:0090304 Not Cancer Driver No 211 0.116 631 93 0.147 0
VRTN VRTN Q9H8Y1 Vertnin chr14 GO:0090304 Not Cancer Driver No 153 0.218 132 27 0.205 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 GO:0090304 Not Cancer Driver No 62 0.132 90 13 0.144 1
WARS2 WARS2 Q9UGM6 Tryptophan--tRNA ligase, mitochondrial chr1 GO:0090304 Not Cancer Driver No 67 0.186 31 4 0.129 5
WDR4 WDR4 P57081 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 chr21 GO:0090304 Not Cancer Driver No 37 0.09 49 4 0.082 2
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0090304 Census, Compendium Yes 164 0.115 373 41 0.11 2
WTAP_ENST00000621533 WTAP Q15007 Pre-mRNA-splicing regulator WTAP chr6 GO:0090304 Not Cancer Driver No 60 0.152 305 50 0.164 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:0090304 Not Cancer Driver No 128 0.15 127 17 0.134 0
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0090304 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0090304 Census, Compendium Yes 88 0.094 479 48 0.1 2
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 GO:0090304 Not Cancer Driver No 112 0.093 64 7 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0090304 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0090304 Not Cancer Driver No 36 0.129 9 1 0.111 2
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0090304 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0090304 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0090304 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0090304 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0090304 Not Cancer Driver No 129 0.136 427 63 0.148 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 GO:0090304 Not Cancer Driver No 62 0.117 109 9 0.083 3
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 GO:0090304 Not Cancer Driver No 59 0.124 62 11 0.177 2
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0090304 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBED9 ZBED9 Q6R2W3 SCAN domain-containing protein 3 chr6 GO:0090304 Not Cancer Driver No 333 0.251 317 84 0.265 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0090304 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0090304 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0090304 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H13 ZC3H13 Q5T200 Zinc finger CCCH domain-containing protein 13 chr13 GO:0090304 Not Cancer Driver No 250 0.15 1443 224 0.155 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0090304 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 GO:0090304 Census Yes 81 0.115 503 56 0.111 1
ZDBF2 ZDBF2 Q9HCK1 DBF4-type zinc finger-containing protein 2 chr2 GO:0090304 Not Cancer Driver No 510 0.217 1664 380 0.228 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0090304 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0090304 Compendium Yes 57 0.169 212 30 0.142 0
ZFP57_ENST00000376881 ZFP57 Q9NU63 Zinc finger protein 57 homolog chr6 GO:0090304 Not Cancer Driver No 82 0.181 153 33 0.216 3
ZGRF1 ZGRF1 Q86YA3 Protein ZGRF1 chr4 GO:0090304 Not Cancer Driver No 216 0.103 881 95 0.108 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0090304 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF445_ENST00000425708 ZNF445 P59923 Zinc finger protein 445 chr3 GO:0090304 Not Cancer Driver No 136 0.132 398 61 0.153 0
ZNF473_ENST00000270617 ZNF473 Q8WTR7 Zinc finger protein 473 chr19 GO:0090304 Not Cancer Driver No 104 0.119 282 27 0.096 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0090304 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZNRD1 POLR1H Q9P1U0 DNA-directed RNA polymerase I subunit RPA12 chr6 GO:0090304 Not Cancer Driver No 6 0.048 14 1 0.071 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0090304 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0090304 Not Cancer Driver No 126 0.117 261 31 0.119 0