Total number of protein in "GO:0090263" GO term: 103
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRA2 | ADGRA2 | Q96PE1 | Adhesion G protein-coupled receptor A2 | chr8 | GO:0090263 | Not Cancer Driver | No | 140 | 0.105 | 417 | 32 | 0.077 | 0 |
| AMER1 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0090263 | Census, Compendium | Yes | 234 | 0.206 | 1039 | 219 | 0.211 | 0 |
| ARNTL | ARNTL | O00327 | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | chr11 | GO:0090263 | Not Cancer Driver | No | 71 | 0.113 | 332 | 40 | 0.12 | 0 |
| ASPM | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0090263 | Not Cancer Driver | No | 554 | 0.159 | 424 | 67 | 0.158 | 0 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | GO:0090263 | Not Cancer Driver | No | 56 | 0.16 | 0 | 0 | 0.0 | 2 |
| BAMBI | BAMBI | Q13145 | BMP and activin membrane-bound inhibitor homolog | chr10 | GO:0090263 | Not Cancer Driver | No | 42 | 0.162 | 31 | 7 | 0.226 | 0 |
| BIRC8 | BIRC8 | Q96P09 | Baculoviral IAP repeat-containing protein 8 | chr19 | GO:0090263 | Not Cancer Driver | No | 79 | 0.335 | 39 | 10 | 0.256 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0090263 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:0090263 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| CDH3 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:0090263 | Not Cancer Driver | No | 87 | 0.105 | 488 | 52 | 0.107 | 2 |
| COL1A1 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0090263 | Census, Compendium | Yes | 247 | 0.169 | 1212 | 214 | 0.177 | 148 |
| CSNK1D | CSNK1D | P48730 | Casein kinase I isoform delta | chr17 | GO:0090263 | Not Cancer Driver | No | 59 | 0.142 | 132 | 16 | 0.121 | 2 |
| CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0090263 | Not Cancer Driver | No | 62 | 0.149 | 133 | 18 | 0.135 | 0 |
| CSNK1G1 | CSNK1G1 | Q9HCP0 | Casein kinase I isoform gamma-1 | chr15 | GO:0090263 | Not Cancer Driver | No | 52 | 0.123 | 130 | 15 | 0.115 | 0 |
| CSNK1G2 | CSNK1G2 | P78368 | Casein kinase I isoform gamma-2 | chr19 | GO:0090263 | Not Cancer Driver | No | 43 | 0.104 | 111 | 13 | 0.117 | 0 |
| CSNK1G3_ENST00000361991 | CSNK1G3 | Q9Y6M4 | Casein kinase I isoform gamma-3 | chr5 | GO:0090263 | Not Cancer Driver | No | 61 | 0.136 | 151 | 22 | 0.146 | 0 |
| CTDNEP1_ENST00000318988 | CTDNEP1 | O95476 | CTD nuclear envelope phosphatase 1 | chr17 | GO:0090263 | Not Cancer Driver | No | 20 | 0.082 | 0 | 0 | 0.0 | 0 |
| DAAM2 | DAAM2 | Q86T65 | Disheveled-associated activator of morphogenesis 2 | chr6 | GO:0090263 | Not Cancer Driver | No | 183 | 0.171 | 272 | 55 | 0.202 | 0 |
| DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0090263 | Not Cancer Driver | No | 163 | 0.195 | 598 | 127 | 0.212 | 1 |
| DAPK3_ENST00000301264 | DAPK3 | O43293 | Death-associated protein kinase 3 | chr19 | GO:0090263 | Not Cancer Driver | No | 56 | 0.123 | 82 | 7 | 0.085 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0090263 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DKK2 | DKK2 | Q9UBU2 | Dickkopf-related protein 2 | chr4 | GO:0090263 | Not Cancer Driver | No | 108 | 0.417 | 70 | 22 | 0.314 | 0 |
| DLX5 | DLX5 | P56178 | Homeobox protein DLX-5 | chr7 | GO:0090263 | Not Cancer Driver | No | 71 | 0.246 | 223 | 57 | 0.256 | 1 |
| EDA | EDA | Q92838 | Ectodysplasin-A | chrX | GO:0090263 | Not Cancer Driver | No | 73 | 0.187 | 243 | 43 | 0.177 | 71 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0090263 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0090263 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| FAM53B | FAM53B | Q14153 | Protein FAM53B | chr10 | GO:0090263 | Not Cancer Driver | No | 46 | 0.109 | 254 | 30 | 0.118 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0090263 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0090263 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FGF9 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0090263 | Not Cancer Driver | No | 41 | 0.197 | 43 | 10 | 0.233 | 1 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0090263 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FRAT1 | FRAT1 | Q92837 | Proto-oncogene FRAT1 | chr10 | GO:0090263 | Not Cancer Driver | No | 6 | 0.022 | 266 | 6 | 0.023 | 0 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0090263 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GID8 | GID8 | Q9NWU2 | Glucose-induced degradation protein 8 homolog | chr20 | GO:0090263 | Not Cancer Driver | No | 30 | 0.132 | 60 | 6 | 0.1 | 0 |
| GPC3_ENST00000370818 | GPC3 | P51654 | Glypican-3 | chrX | GO:0090263 | Census | Yes | 89 | 0.153 | 86 | 11 | 0.128 | 1 |
| GPC5 | GPC5 | P78333 | Glypican-5 | chr13 | GO:0090263 | Census | Yes | 239 | 0.418 | 117 | 56 | 0.479 | 0 |
| GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | GO:0090263 | Not Cancer Driver | No | 82 | 0.203 | 75 | 19 | 0.253 | 0 |
| GSKIP_ENST00000438650 | GSKIP | Q9P0R6 | GSK3B-interacting protein | chr14 | GO:0090263 | Not Cancer Driver | No | 11 | 0.079 | 32 | 1 | 0.031 | 0 |
| HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0090263 | Not Cancer Driver | No | 23 | 0.085 | 193 | 21 | 0.109 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0090263 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| JRK_ENST00000571961 | JRK | O75564 | Jerky protein homolog | chr8 | GO:0090263 | Not Cancer Driver | No | 56 | 0.101 | 140 | 17 | 0.121 | 0 |
| JUP | JUP | P14923 | Junction plakoglobin | chr17 | GO:0090263 | Not Cancer Driver | No | 112 | 0.15 | 241 | 37 | 0.154 | 0 |
| KANK1_ENST00000382303 | KANK1 | Q14678 | KN motif and ankyrin repeat domain-containing protein 1 | chr9 | GO:0090263 | Not Cancer Driver | No | 183 | 0.135 | 804 | 100 | 0.124 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:0090263 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| LGR5 | LGR5 | O75473 | Leucine-rich repeat-containing G-protein coupled receptor 5 | chr12 | GO:0090263 | Not Cancer Driver | No | 124 | 0.137 | 13 | 2 | 0.154 | 0 |
| LGR6 | LGR6 | Q9HBX8 | Leucine-rich repeat-containing G-protein coupled receptor 6 | chr1 | GO:0090263 | Not Cancer Driver | No | 163 | 0.169 | 101 | 16 | 0.158 | 0 |
| LRRK1 | LRRK1 | Q38SD2 | Leucine-rich repeat serine/threonine-protein kinase 1 | chr15 | GO:0090263 | Not Cancer Driver | No | 289 | 0.143 | 261 | 33 | 0.126 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0090263 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| LYPD6_ENST00000409381 | LYPD6 | Q86Y78 | Ly6/PLAUR domain-containing protein 6 | chr2 | GO:0090263 | Not Cancer Driver | No | 17 | 0.099 | 8 | 0 | 0.0 | 0 |
| NFKB1_ENST00000505458 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | GO:0090263 | Not Cancer Driver | No | 104 | 0.107 | 344 | 38 | 0.11 | 0 |
| NLE1 | NLE1 | Q9NVX2 | Notchless protein homolog 1 | chr17 | GO:0090263 | Not Cancer Driver | No | 60 | 0.124 | 21 | 3 | 0.143 | 0 |
| NRARP | NRARP | Q7Z6K4 | Notch-regulated ankyrin repeat-containing protein | chr9 | GO:0090263 | Not Cancer Driver | No | 9 | 0.079 | 11 | 1 | 0.091 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0090263 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | GO:0090263 | Not Cancer Driver | No | 136 | 0.175 | 687 | 128 | 0.186 | 0 |
| PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | GO:0090263 | Not Cancer Driver | No | 60 | 0.157 | 134 | 24 | 0.179 | 0 |
| PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | GO:0090263 | Not Cancer Driver | No | 65 | 0.136 | 243 | 31 | 0.128 | 0 |
| PPM1N | PPM1N | Q8N819 | Probable protein phosphatase 1N | chr19 | GO:0090263 | Not Cancer Driver | No | 31 | 0.072 | 152 | 7 | 0.046 | 0 |
| PRDM15 | PRDM15 | P57071 | PR domain zinc finger protein 15 | chr21 | GO:0090263 | Not Cancer Driver | No | 159 | 0.106 | 800 | 75 | 0.094 | 0 |
| PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0090263 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
| RBPJ_ENST00000361572 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | GO:0090263 | Not Cancer Driver | No | 49 | 0.098 | 151 | 19 | 0.126 | 2 |
| RECK | RECK | O95980 | Reversion-inducing cysteine-rich protein with Kazal motifs | chr9 | GO:0090263 | Not Cancer Driver | No | 115 | 0.118 | 9 | 2 | 0.222 | 0 |
| RNF146 | RNF146 | Q9NTX7 | E3 ubiquitin-protein ligase RNF146 | chr6 | GO:0090263 | Not Cancer Driver | No | 37 | 0.103 | 206 | 24 | 0.117 | 0 |
| RNF220_ENST00000361799 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | GO:0090263 | Not Cancer Driver | No | 104 | 0.184 | 401 | 75 | 0.187 | 0 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0090263 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RPS12 | RPS12 | P25398 | 40S ribosomal protein S12 | chr6 | GO:0090263 | Not Cancer Driver | No | 17 | 0.129 | 0 | 0 | 0.0 | 0 |
| RSPO1_ENST00000401068 | RSPO1 | Q2MKA7 | R-spondin-1 | chr1 | GO:0090263 | Not Cancer Driver | No | 59 | 0.224 | 82 | 16 | 0.195 | 0 |
| RSPO2 | RSPO2 | Q6UXX9 | R-spondin-2 | chr8 | GO:0090263 | Census | Yes | 96 | 0.395 | 41 | 10 | 0.244 | 1 |
| RSPO3 | RSPO3 | Q9BXY4 | R-spondin-3 | chr6 | GO:0090263 | Census | Yes | 44 | 0.162 | 100 | 12 | 0.12 | 0 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0090263 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
| SCEL | SCEL | O95171 | Sciellin | chr13 | GO:0090263 | Not Cancer Driver | No | 137 | 0.199 | 600 | 126 | 0.21 | 0 |
| SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0090263 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0090263 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0090263 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SFRP4 | SFRP4 | Q6FHJ7 | Secreted frizzled-related protein 4 | chr7 | GO:0090263 | Census | Yes | 81 | 0.234 | 68 | 22 | 0.324 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0090263 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0090263 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| SOX4 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | GO:0090263 | Not Cancer Driver | No | 28 | 0.059 | 400 | 24 | 0.06 | 4 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0090263 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| TBL1X | TBL1X | O60907 | F-box-like/WD repeat-containing protein TBL1X | chrX | GO:0090263 | Not Cancer Driver | No | 85 | 0.147 | 181 | 35 | 0.193 | 0 |
| TBL1XR1 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0090263 | Census, Compendium | Yes | 82 | 0.16 | 136 | 19 | 0.14 | 4 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0090263 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TMEM198_ENST00000373883 | TMEM198 | Q66K66 | Transmembrane protein 198 | chr2 | GO:0090263 | Not Cancer Driver | No | 58 | 0.161 | 102 | 22 | 0.216 | 0 |
| TMEM9_ENST00000485839 | TMEM9 | Q9P0T7 | Proton-transporting V-type ATPase complex assembly regulator TMEM9 | chr1 | GO:0090263 | Not Cancer Driver | No | 22 | 0.12 | 23 | 3 | 0.13 | 0 |
| TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:0090263 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
| TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:0090263 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
| TRPM4 | TRPM4 | Q8TD43 | Transient receptor potential cation channel subfamily M member 4 | chr19 | GO:0090263 | Not Cancer Driver | No | 152 | 0.125 | 149 | 18 | 0.121 | 12 |
| TTC21B | TTC21B | Q7Z4L5 | Tetratricopeptide repeat protein 21B | chr2 | GO:0090263 | Not Cancer Driver | No | 176 | 0.134 | 73 | 14 | 0.192 | 11 |
| UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0090263 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0090263 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| USP34 | USP34 | Q70CQ2 | Ubiquitin carboxyl-terminal hydrolase 34 | chr2 | GO:0090263 | Not Cancer Driver | No | 436 | 0.123 | 725 | 90 | 0.124 | 0 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0090263 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| USP8 | USP8 | P40818 | Ubiquitin carboxyl-terminal hydrolase 8 | chr15 | GO:0090263 | Census, Compendium | Yes | 122 | 0.109 | 602 | 69 | 0.115 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0090263 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0090263 | Not Cancer Driver | No | 68 | 0.085 | 99 | 9 | 0.091 | 1 |
| WLS_ENST00000262348 | WLS | Q5T9L3 | Protein wntless homolog | chr1 | GO:0090263 | Not Cancer Driver | No | 71 | 0.131 | 14 | 3 | 0.214 | 0 |
| WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0090263 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
| WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | GO:0090263 | Census, Compendium | Yes | 223 | 0.097 | 1868 | 167 | 0.089 | 0 |
| WNT10B | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0090263 | Not Cancer Driver | No | 56 | 0.144 | 84 | 16 | 0.19 | 2 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0090263 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0090263 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0090263 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |
| ZBED3 | ZBED3 | Q96IU2 | Zinc finger BED domain-containing protein 3 | chr5 | GO:0090263 | Not Cancer Driver | No | 2 | 0.009 | 229 | 2 | 0.009 | 0 |
| ZEB2_ENST00000558170 | ZEB2 | O60315 | Zinc finger E-box-binding homeobox 2 | chr2 | GO:0090263 | Not Cancer Driver | No | 299 | 0.246 | 859 | 211 | 0.246 | 2 |