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Total number of protein in "GO:0071902" GO term:  137

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0071902 Not Cancer Driver No 85 0.122 27 1 0.037 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0071902 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0071902 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0071902 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0071902 Not Cancer Driver No 31 0.077 297 21 0.071 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0071902 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0071902 Not Cancer Driver No 194 0.117 353 36 0.102 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0071902 Not Cancer Driver No 170 0.106 1141 127 0.111 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0071902 Census, Compendium Yes 120 0.139 619 88 0.142 4
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0071902 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0071902 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0071902 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0071902 Compendium Yes 141 0.136 601 70 0.116 19
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0071902 Not Cancer Driver No 31 0.091 43 5 0.116 0
CAB39L_ENST00000347776 CAB39L Q9H9S4 Calcium-binding protein 39-like chr13 GO:0071902 Not Cancer Driver No 41 0.122 38 2 0.053 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0071902 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0071902 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0071902 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0071902 Not Cancer Driver No 40 0.108 31 1 0.032 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0071902 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0071902 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0071902 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0071902 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0071902 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0071902 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0071902 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0071902 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0071902 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0071902 Not Cancer Driver No 31 0.086 100 8 0.08 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0071902 Not Cancer Driver No 56 0.215 24 7 0.292 32
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0071902 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0071902 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0071902 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0071902 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0071902 Not Cancer Driver No 207 0.152 105 10 0.095 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0071902 Not Cancer Driver No 24 0.126 6 1 0.167 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0071902 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0071902 Not Cancer Driver No 9 0.114 10 2 0.2 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0071902 Census Yes 133 0.137 124 17 0.137 20
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0071902 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAZAP2_ENST00000412716 DAZAP2 Q15038 DAZ-associated protein 2 chr12 GO:0071902 Not Cancer Driver No 17 0.101 68 7 0.103 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 GO:0071902 Not Cancer Driver No 75 0.111 333 26 0.078 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0071902 Not Cancer Driver No 68 0.111 311 22 0.071 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0071902 Census, Compendium Yes 133 0.201 301 47 0.156 18
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0071902 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0071902 Not Cancer Driver No 58 0.218 47 8 0.17 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0071902 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0071902 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0071902 Not Cancer Driver No 97 0.135 437 58 0.133 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0071902 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0071902 Census, Compendium Yes 444 0.367 223 35 0.157 1
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0071902 Not Cancer Driver No 182 0.185 140 24 0.171 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0071902 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0071902 Not Cancer Driver No 192 0.207 213 45 0.211 0
ETAA1 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 GO:0071902 Not Cancer Driver No 101 0.109 735 75 0.102 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0071902 Census, Compendium Yes 120 0.161 284 44 0.155 11
FAM20A FAM20A Q96MK3 Pseudokinase FAM20A chr17 GO:0071902 Not Cancer Driver No 62 0.115 94 9 0.096 3
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0071902 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0071902 Not Cancer Driver No 113 0.173 158 26 0.165 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0071902 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0071902 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0071902 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0071902 Not Cancer Driver No 72 0.104 146 3 0.021 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0071902 Census Yes 12 0.11 109 12 0.11 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0071902 Census, Compendium Yes 100 0.138 254 43 0.169 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0071902 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0071902 Not Cancer Driver No 39 0.217 44 12 0.273 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0071902 Not Cancer Driver No 39 0.145 16 3 0.188 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 GO:0071902 Not Cancer Driver No 107 0.117 856 103 0.12 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0071902 Not Cancer Driver No 183 0.11 351 35 0.1 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0071902 Not Cancer Driver No 9 0.05 45 1 0.022 0
LTF LTF P02788 Lactotransferrin chr3 GO:0071902 Not Cancer Driver No 131 0.185 21 4 0.19 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0071902 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0071902 Census Yes 58 0.145 105 14 0.133 4
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0071902 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0071902 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0071902 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0071902 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0071902 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0071902 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0071902 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0071902 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0071902 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0071902 Not Cancer Driver No 37 0.132 120 16 0.133 0
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 GO:0071902 Not Cancer Driver No 37 0.113 45 3 0.067 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0071902 Not Cancer Driver No 23 0.074 64 2 0.031 0
MTCP1_ENST00000362018 MTCP1 P56278 Protein p13 MTCP-1 chrX GO:0071902 Census, Compendium Yes 14 0.131 6 0 0.0 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0071902 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0071902 Not Cancer Driver No 37 0.115 33 3 0.091 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0071902 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0071902 Census Yes 37 0.154 99 22 0.222 2
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0071902 Not Cancer Driver No 30 0.103 157 13 0.083 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0071902 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0071902 Not Cancer Driver No 113 0.117 375 35 0.093 10
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0071902 Not Cancer Driver No 41 0.133 12 1 0.083 8
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0071902 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0071902 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0071902 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0071902 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0071902 Not Cancer Driver No 49 0.113 140 25 0.179 0
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0071902 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0071902 Not Cancer Driver No 216 0.144 803 116 0.144 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0071902 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0071902 Census, Compendium Yes 99 0.513 46 13 0.283 2
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 GO:0071902 Not Cancer Driver No 212 0.124 366 50 0.137 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0071902 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0071902 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0071902 Not Cancer Driver No 176 0.132 241 21 0.087 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0071902 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0071902 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0071902 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0071902 Not Cancer Driver No 117 0.127 143 19 0.133 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0071902 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0071902 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0071902 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0071902 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071902 Census Yes 53 0.099 130 11 0.085 1
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0071902 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0071902 Not Cancer Driver No 70 0.144 231 30 0.13 0
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 GO:0071902 Not Cancer Driver No 49 0.114 118 14 0.119 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0071902 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0071902 Census Yes 96 0.151 131 27 0.206 5
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 GO:0071902 Not Cancer Driver No 81 0.161 232 34 0.147 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0071902 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0071902 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0071902 Not Cancer Driver No 123 0.137 494 64 0.13 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0071902 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0071902 Census Yes 30 0.263 5 1 0.2 0
TCL1B TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 GO:0071902 Not Cancer Driver No 38 0.297 11 1 0.091 0
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 GO:0071902 Not Cancer Driver No 113 0.135 154 23 0.149 5
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0071902 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0071902 Not Cancer Driver No 141 0.137 35 3 0.086 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0071902 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0071902 Not Cancer Driver No 70 0.114 285 33 0.116 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0071902 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0071902 Not Cancer Driver No 67 0.128 62 7 0.113 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0071902 Not Cancer Driver No 66 0.174 0 0 0.0 2