Total number of protein in "GO:0071216" GO term: 48
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACOD1 | ACOD1 | A6NK06 | Cis-aconitate decarboxylase | chr13 | GO:0071216 | Not Cancer Driver | No | 5 | 0.01 | 36 | 0 | 0.0 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0071216 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| ATG10 | ATG10 | Q9H0Y0 | Ubiquitin-like-conjugating enzyme ATG10 | chr5 | GO:0071216 | Not Cancer Driver | No | 22 | 0.1 | 9 | 1 | 0.111 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0071216 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:0071216 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
| CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0071216 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
| CCDC47_ENST00000403162 | CCDC47 | Q96A33 | PAT complex subunit CCDC47 | chr17 | GO:0071216 | Not Cancer Driver | No | 49 | 0.101 | 265 | 23 | 0.087 | 0 |
| CD14 | CD14 | P08571 | Monocyte differentiation antigen CD14 | chr5 | GO:0071216 | Not Cancer Driver | No | 42 | 0.112 | 60 | 5 | 0.083 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0071216 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CDA | CDA | P32320 | Cytidine deaminase | chr1 | GO:0071216 | Not Cancer Driver | No | 21 | 0.144 | 8 | 0 | 0.0 | 0 |
| CLEC7A | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0071216 | Not Cancer Driver | No | 43 | 0.174 | 46 | 2 | 0.043 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0071216 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| DEFB124 | DEFB124 | Q8NES8 | Beta-defensin 124 | chr20 | GO:0071216 | Not Cancer Driver | No | 9 | 0.127 | 3 | 0 | 0.0 | 0 |
| EIF2AK3 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0071216 | Not Cancer Driver | No | 149 | 0.134 | 410 | 51 | 0.124 | 1 |
| EME1_ENST00000338165 | EME1 | Q96AY2 | Crossover junction endonuclease EME1 | chr17 | GO:0071216 | Not Cancer Driver | No | 56 | 0.098 | 296 | 30 | 0.101 | 0 |
| FAM49B_ENST00000519540 | CYRIB | Q9NUQ9 | CYFIP-related Rac1 interactor B | chr8 | GO:0071216 | Not Cancer Driver | No | 53 | 0.164 | 78 | 11 | 0.141 | 0 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | GO:0071216 | Not Cancer Driver | No | 139 | 0.133 | 192 | 32 | 0.167 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0071216 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0071216 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0071216 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | GO:0071216 | Not Cancer Driver | No | 73 | 0.112 | 282 | 35 | 0.124 | 0 |
| IGFBPL1 | IGFBPL1 | Q8WX77 | Insulin-like growth factor-binding protein-like 1 | chr9 | GO:0071216 | Not Cancer Driver | No | 31 | 0.112 | 75 | 12 | 0.16 | 0 |
| LBP | LBP | P18428 | Lipopolysaccharide-binding protein | chr20 | GO:0071216 | Not Cancer Driver | No | 84 | 0.175 | 6 | 0 | 0.0 | 0 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0071216 | Not Cancer Driver | No | 39 | 0.108 | 25 | 1 | 0.04 | 0 |
| MUS81 | MUS81 | Q96NY9 | Crossover junction endonuclease MUS81 | chr11 | GO:0071216 | Not Cancer Driver | No | 67 | 0.122 | 232 | 38 | 0.164 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0071216 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0071216 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0071216 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| PPP1R15B | PPP1R15B | Q5SWA1 | Protein phosphatase 1 regulatory subunit 15B | chr1 | GO:0071216 | Not Cancer Driver | No | 72 | 0.101 | 415 | 45 | 0.108 | 1 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0071216 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0071216 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| SCIMP | SCIMP | Q6UWF3 | SLP adapter and CSK-interacting membrane protein | chr17 | GO:0071216 | Not Cancer Driver | No | 10 | 0.069 | 73 | 9 | 0.123 | 0 |
| SELENOS | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0071216 | Not Cancer Driver | No | 7 | 0.037 | 122 | 6 | 0.049 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0071216 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:0071216 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
| SMC1A | SMC1A | Q14683 | Structural maintenance of chromosomes protein 1A | chrX | GO:0071216 | Census, Compendium | Yes | 200 | 0.162 | 717 | 114 | 0.159 | 21 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0071216 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0071216 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TLR1_ENST00000502213 | TLR1 | Q15399 | Toll-like receptor 1 | chr4 | GO:0071216 | Not Cancer Driver | No | 107 | 0.136 | 1 | 0 | 0.0 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0071216 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0071216 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR6 | TLR6 | Q9Y2C9 | Toll-like receptor 6 | chr4 | GO:0071216 | Not Cancer Driver | No | 99 | 0.124 | 1 | 0 | 0.0 | 0 |
| TMCO1 | TMCO1 | Q9UM00 | Calcium load-activated calcium channel | chr1 | GO:0071216 | Not Cancer Driver | No | 31 | 0.13 | 49 | 5 | 0.102 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0071216 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0071216 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | GO:0071216 | Not Cancer Driver | No | 61 | 0.156 | 77 | 14 | 0.182 | 0 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | GO:0071216 | Not Cancer Driver | No | 105 | 0.118 | 203 | 10 | 0.049 | 39 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0071216 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |