Total number of protein in "GO:0070527" GO term: 43
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0070527 | Not Cancer Driver | No | 112 | 0.299 | 43 | 5 | 0.116 | 5 |
| ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | GO:0070527 | Not Cancer Driver | No | 73 | 0.195 | 42 | 10 | 0.238 | 16 |
| ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | GO:0070527 | Not Cancer Driver | No | 108 | 0.121 | 195 | 30 | 0.154 | 6 |
| BLOC1S4 | BLOC1S4 | Q9NUP1 | Biogenesis of lysosome-related organelles complex 1 subunit 4 | chr4 | GO:0070527 | Not Cancer Driver | No | 11 | 0.051 | 102 | 1 | 0.01 | 0 |
| CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | GO:0070527 | Not Cancer Driver | No | 32 | 0.133 | 27 | 5 | 0.185 | 0 |
| COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0070527 | Not Cancer Driver | No | 97 | 0.128 | 306 | 52 | 0.17 | 61 |
| CSRP1_ENST00000340006 | CSRP1 | P21291 | Cysteine and glycine-rich protein 1 | chr1 | GO:0070527 | Not Cancer Driver | No | 18 | 0.093 | 28 | 4 | 0.143 | 0 |
| FERMT3 | FERMT3 | Q86UX7 | Fermitin family homolog 3 | chr11 | GO:0070527 | Not Cancer Driver | No | 99 | 0.148 | 108 | 14 | 0.13 | 0 |
| FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0070527 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0070527 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0070527 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| FIBP | FIBP | O43427 | Acidic fibroblast growth factor intracellular-binding protein | chr11 | GO:0070527 | Not Cancer Driver | No | 32 | 0.088 | 15 | 2 | 0.133 | 0 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0070527 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0070527 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
| GATA1 | GATA1 | P15976 | Erythroid transcription factor | chrX | GO:0070527 | Census, Compendium | Yes | 68 | 0.165 | 242 | 41 | 0.169 | 5 |
| GP1BA | GP1BA | P07359 | Platelet glycoprotein Ib alpha chain | chr17 | GO:0070527 | Not Cancer Driver | No | 65 | 0.1 | 247 | 18 | 0.073 | 9 |
| HBB | HBB | P68871 | Hemoglobin subunit beta | chr11 | GO:0070527 | Not Cancer Driver | No | 45 | 0.306 | 7 | 2 | 0.286 | 5 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0070527 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0070527 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| ITGB3 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0070527 | Not Cancer Driver | No | 124 | 0.157 | 66 | 5 | 0.076 | 30 |
| METAP1 | METAP1 | P53582 | Methionine aminopeptidase 1 | chr4 | GO:0070527 | Not Cancer Driver | No | 37 | 0.096 | 61 | 3 | 0.049 | 0 |
| MPL | MPL | P40238 | Thrombopoietin receptor | chr1 | GO:0070527 | Census | Yes | 77 | 0.121 | 129 | 19 | 0.147 | 14 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0070527 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
| MYL12A_ENST00000217652 | MYL12A | P19105 | Myosin regulatory light chain 12A | chr18 | GO:0070527 | Not Cancer Driver | No | 19 | 0.111 | 70 | 13 | 0.186 | 0 |
| MYL9 | MYL9 | P24844 | Myosin regulatory light polypeptide 9 | chr20 | GO:0070527 | Not Cancer Driver | No | 34 | 0.198 | 82 | 19 | 0.232 | 0 |
| P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | GO:0070527 | Not Cancer Driver | No | 57 | 0.167 | 21 | 2 | 0.095 | 3 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0070527 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
| PEAR1 | PEAR1 | Q5VY43 | Platelet endothelial aggregation receptor 1 | chr1 | GO:0070527 | Not Cancer Driver | No | 152 | 0.147 | 233 | 42 | 0.18 | 0 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0070527 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0070527 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PLEK | PLEK | P08567 | Pleckstrin | chr2 | GO:0070527 | Not Cancer Driver | No | 81 | 0.231 | 39 | 9 | 0.231 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0070527 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0070527 | Census, Compendium | Yes | 73 | 0.123 | 192 | 25 | 0.13 | 0 |
| RAP2B | RAP2B | P61225 | Ras-related protein Rap-2b | chr3 | GO:0070527 | Not Cancer Driver | No | 22 | 0.12 | 0 | 0 | 0.0 | 0 |
| SLC7A11 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0070527 | Not Cancer Driver | No | 70 | 0.14 | 15 | 2 | 0.133 | 0 |
| STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0070527 | Not Cancer Driver | No | 97 | 0.163 | 111 | 23 | 0.207 | 18 |
| STXBP3 | STXBP3 | O00186 | Syntaxin-binding protein 3 | chr1 | GO:0070527 | Not Cancer Driver | No | 59 | 0.1 | 64 | 9 | 0.141 | 0 |
| TLN1 | TLN1 | Q9Y490 | Talin-1 | chr9 | GO:0070527 | Not Cancer Driver | No | 278 | 0.109 | 1109 | 126 | 0.114 | 0 |
| TSPAN32 | TSPAN32 | Q96QS1 | Tetraspanin-32 | chr11 | GO:0070527 | Not Cancer Driver | No | 33 | 0.103 | 8 | 3 | 0.375 | 0 |
| TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0070527 | Not Cancer Driver | No | 119 | 0.134 | 197 | 17 | 0.086 | 0 |
| UBASH3B | UBASH3B | Q8TF42 | Ubiquitin-associated and SH3 domain-containing protein B | chr11 | GO:0070527 | Not Cancer Driver | No | 86 | 0.133 | 73 | 6 | 0.082 | 0 |
| VCL | VCL | P18206 | Vinculin | chr10 | GO:0070527 | Not Cancer Driver | No | 114 | 0.101 | 673 | 80 | 0.119 | 2 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0070527 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |