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Total number of protein in "GO:0070507" GO term:  134

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0070507 Census, Compendium Yes 139 0.123 604 73 0.121 2
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0070507 Census Yes 474 0.121 2281 268 0.117 1
ANKRD53 ANKRD53 Q8N9V6 Ankyrin repeat domain-containing protein 53 chr2 GO:0070507 Not Cancer Driver No 57 0.108 252 21 0.083 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0070507 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0070507 Not Cancer Driver No 117 0.051 1725 78 0.045 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0070507 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0070507 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0070507 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL3 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0070507 Not Cancer Driver No 16 0.088 0 0 0.0 2
ATAT1_ENST00000376485 ATAT1 Q5SQI0 Alpha-tubulin N-acetyltransferase 1 chr6 GO:0070507 Not Cancer Driver No 31 0.074 271 20 0.074 0
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 GO:0070507 Not Cancer Driver No 95 0.107 797 82 0.103 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0070507 Not Cancer Driver No 124 0.127 656 86 0.131 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 GO:0070507 Not Cancer Driver No 115 0.14 546 73 0.134 10
C16orf45 BMERB1 Q96MC5 bMERB domain-containing protein 1 chr16 GO:0070507 Not Cancer Driver No 32 0.157 102 16 0.157 0
CAMSAP1 CAMSAP1 Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 chr9 GO:0070507 Not Cancer Driver No 208 0.13 1129 158 0.14 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 GO:0070507 Not Cancer Driver No 176 0.118 1025 127 0.124 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 GO:0070507 Not Cancer Driver No 132 0.106 889 81 0.091 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0070507 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCSAP CCSAP Q6IQ19 Centriole, cilia and spindle-associated protein chr1 GO:0070507 Not Cancer Driver No 22 0.081 241 19 0.079 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0070507 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK2AP2 CDK2AP2 O75956 Cyclin-dependent kinase 2-associated protein 2 chr11 GO:0070507 Not Cancer Driver No 10 0.079 126 10 0.079 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0070507 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0070507 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0070507 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEP70_ENST00000484888 CEP70 Q8NHQ1 Centrosomal protein of 70 kDa chr3 GO:0070507 Not Cancer Driver No 79 0.132 223 32 0.143 0
CEP97 CEP97 Q8IW35 Centrosomal protein of 97 kDa chr3 GO:0070507 Not Cancer Driver No 95 0.11 405 41 0.101 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:0070507 Not Cancer Driver No 18 0.092 110 6 0.055 0
CHMP1B CHMP1B Q7LBR1 Charged multivesicular body protein 1b chr18 GO:0070507 Not Cancer Driver No 23 0.116 133 16 0.12 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 GO:0070507 Not Cancer Driver No 29 0.131 161 22 0.137 0
CHMP2B CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 GO:0070507 Not Cancer Driver No 28 0.131 183 25 0.137 4
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0070507 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0070507 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0070507 Not Cancer Driver No 25 0.112 201 22 0.109 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 GO:0070507 Not Cancer Driver No 33 0.142 224 31 0.138 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0070507 Not Cancer Driver No 24 0.11 195 18 0.092 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0070507 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHMP7_ENST00000313219 CHMP7 Q8WUX9 Charged multivesicular body protein 7 chr8 GO:0070507 Not Cancer Driver No 50 0.11 140 15 0.107 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0070507 Not Cancer Driver No 24 0.126 6 1 0.167 0
CKAP2 CKAP2 Q8WWK9 Cytoskeleton-associated protein 2 chr13 GO:0070507 Not Cancer Driver No 72 0.105 522 57 0.109 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0070507 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0070507 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0070507 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0070507 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CLIP3_ENST00000593074 CLIP3 Q96DZ5 CAP-Gly domain-containing linker protein 3 chr19 GO:0070507 Not Cancer Driver No 78 0.143 218 22 0.101 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0070507 Census, Compendium Yes 116 0.121 213 31 0.146 3
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0070507 Census Yes 172 0.135 817 111 0.136 11
DIXDC1 DIXDC1 Q155Q3 Dixin chr11 GO:0070507 Not Cancer Driver No 72 0.105 495 55 0.111 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 GO:0070507 Not Cancer Driver No 35 0.095 31 0 0.0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0070507 Not Cancer Driver No 505 0.109 495 62 0.125 21
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0070507 Not Cancer Driver No 135 0.177 447 73 0.163 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0070507 Not Cancer Driver No 34 0.149 25 6 0.24 0
EML2_ENST00000245925 EML2 O95834 Echinoderm microtubule-associated protein-like 2 chr19 GO:0070507 Not Cancer Driver No 97 0.149 20 3 0.15 0
EML3_ENST00000394773 EML3 Q32P44 Echinoderm microtubule-associated protein-like 3 chr11 GO:0070507 Not Cancer Driver No 102 0.114 321 29 0.09 0
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0070507 Census, Compendium Yes 346 0.352 74 28 0.378 0
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0070507 Not Cancer Driver No 25 0.174 141 24 0.17 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0070507 Census Yes 103 0.125 245 34 0.139 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0070507 Not Cancer Driver No 70 0.286 96 33 0.344 2
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0070507 Not Cancer Driver No 46 0.1 134 12 0.09 0
GBA2 GBA2 Q9HCG7 Non-lysosomal glucosylceramidase chr9 GO:0070507 Not Cancer Driver No 96 0.104 157 12 0.076 3
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0070507 Not Cancer Driver No 67 0.088 434 42 0.097 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0070507 Not Cancer Driver No 79 0.115 240 21 0.087 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0070507 Not Cancer Driver No 56 0.133 146 13 0.089 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0070507 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL3 HDGFL3 Q9Y3E1 Hepatoma-derived growth factor-related protein 3 chr15 GO:0070507 Not Cancer Driver No 25 0.123 163 18 0.11 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0070507 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0070507 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0070507 Not Cancer Driver No 15 0.023 200 5 0.025 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0070507 Not Cancer Driver No 102 0.101 629 42 0.067 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 GO:0070507 Not Cancer Driver No 70 0.107 179 24 0.134 3
KIF15 KIF15 Q9NS87 Kinesin-like protein KIF15 chr3 GO:0070507 Not Cancer Driver No 148 0.107 819 93 0.114 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0070507 Not Cancer Driver No 114 0.127 405 60 0.148 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0070507 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0070507 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0070507 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0070507 Compendium Yes 367 0.201 1726 340 0.197 0
MAP6 MAP6 Q96JE9 Microtubule-associated protein 6 chr11 GO:0070507 Not Cancer Driver No 76 0.093 788 75 0.095 0
MAP6D1 MAP6D1 Q9H9H5 MAP6 domain-containing protein 1 chr3 GO:0070507 Not Cancer Driver No 8 0.04 173 8 0.046 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0070507 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0070507 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0070507 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0070507 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0070507 Compendium Yes 124 0.157 445 70 0.157 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0070507 Not Cancer Driver No 75 0.154 483 74 0.153 46
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0070507 Census, Compendium Yes 226 0.163 62 15 0.242 19
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX GO:0070507 Not Cancer Driver No 86 0.129 86 16 0.186 4
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0070507 Not Cancer Driver No 23 0.126 83 6 0.072 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 GO:0070507 Not Cancer Driver No 287 0.139 858 122 0.142 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0070507 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NIN NIN Q8N4C6 Ninein chr14 GO:0070507 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0070507 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OCLN OCLN Q16625 Occludin chr5 GO:0070507 Not Cancer Driver No 54 0.103 244 21 0.086 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0070507 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0070507 Not Cancer Driver No 57 0.105 299 30 0.1 2
PATJ PATJ Q8NI35 InaD-like protein chr1 GO:0070507 Not Cancer Driver No 261 0.145 918 142 0.155 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0070507 Not Cancer Driver No 85 0.098 272 22 0.081 0
PHLDB1 PHLDB1 Q86UU1 Pleckstrin homology-like domain family B member 1 chr11 GO:0070507 Not Cancer Driver No 160 0.116 1071 130 0.121 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0070507 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0070507 Not Cancer Driver No 87 0.144 119 13 0.109 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0070507 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0070507 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRUNE1 PRUNE1 Q86TP1 Exopolyphosphatase PRUNE1 chr1 GO:0070507 Not Cancer Driver No 43 0.095 93 14 0.151 4
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0070507 Not Cancer Driver No 30 0.083 361 30 0.083 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0070507 Census, Compendium Yes 66 0.344 2 1 0.5 6
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0070507 Not Cancer Driver No 10 0.054 42 5 0.119 0
RASSF1 RASSF1 Q9NS23 Ras association domain-containing protein 1 chr3 GO:0070507 Not Cancer Driver No 36 0.105 79 3 0.038 0
RASSF7 RASSF7 Q02833 Ras association domain-containing protein 7 chr11 GO:0070507 Not Cancer Driver No 28 0.075 278 19 0.068 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0070507 Census, Compendium Yes 99 0.513 46 13 0.283 2
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0070507 Not Cancer Driver No 14 0.074 117 7 0.06 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0070507 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0070507 Not Cancer Driver No 22 0.091 48 4 0.083 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 GO:0070507 Not Cancer Driver No 120 0.108 612 59 0.096 0
SLAIN1_ENST00000466548 SLAIN1 Q8ND83 SLAIN motif-containing protein 1 chr13 GO:0070507 Not Cancer Driver No 62 0.109 485 58 0.12 0
SLAIN2 SLAIN2 Q9P270 SLAIN motif-containing protein 2 chr4 GO:0070507 Not Cancer Driver No 62 0.107 562 60 0.107 0
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 GO:0070507 Not Cancer Driver No 210 0.304 89 29 0.326 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0070507 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 GO:0070507 Not Cancer Driver No 136 0.114 636 83 0.131 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:0070507 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPEF1 SPEF1 Q9Y4P9 Sperm flagellar protein 1 chr20 GO:0070507 Not Cancer Driver No 19 0.081 89 5 0.056 0
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0070507 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0070507 Not Cancer Driver No 34 0.19 122 23 0.189 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0070507 Not Cancer Driver No 116 0.116 601 59 0.098 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0070507 Not Cancer Driver No 156 0.131 60 9 0.15 11
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 GO:0070507 Not Cancer Driver No 230 0.134 703 101 0.144 3
TPPP TPPP O94811 Tubulin polymerization-promoting protein chr5 GO:0070507 Not Cancer Driver No 33 0.151 149 21 0.141 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0070507 Census Yes 311 0.132 1990 266 0.134 0
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 GO:0070507 Not Cancer Driver No 92 0.123 695 86 0.124 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0070507 Not Cancer Driver No 75 0.109 507 60 0.118 4
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 GO:0070507 Not Cancer Driver No 106 0.146 89 21 0.236 1
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 GO:0070507 Not Cancer Driver No 63 0.176 98 17 0.173 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0070507 Not Cancer Driver No 142 0.163 231 34 0.147 44
TTBK2 TTBK2 Q6IQ55 Tau-tubulin kinase 2 chr15 GO:0070507 Not Cancer Driver No 151 0.121 848 107 0.126 0
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 GO:0070507 Not Cancer Driver No 91 0.205 61 16 0.262 2
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0070507 Not Cancer Driver No 52 0.117 195 22 0.113 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0070507 Not Cancer Driver No 77 0.219 37 5 0.135 0