Total number of protein in "GO:0061041" GO term: 95
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABAT_ENST00000268251 | ABAT | P80404 | 4-aminobutyrate aminotransferase, mitochondrial | chr16 | GO:0061041 | Not Cancer Driver | No | 84 | 0.168 | 28 | 5 | 0.179 | 1 |
| ABCC8_ENST00000389817 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0061041 | Not Cancer Driver | No | 255 | 0.161 | 138 | 23 | 0.167 | 97 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | GO:0061041 | Not Cancer Driver | No | 50 | 0.133 | 39 | 4 | 0.103 | 17 |
| ADAMTS18 | ADAMTS18 | Q8TE60 | A disintegrin and metalloproteinase with thrombospondin motifs 18 | chr16 | GO:0061041 | Not Cancer Driver | No | 382 | 0.313 | 142 | 63 | 0.444 | 2 |
| AJAP1 | AJAP1 | Q9UKB5 | Adherens junction-associated protein 1 | chr1 | GO:0061041 | Not Cancer Driver | No | 103 | 0.251 | 271 | 64 | 0.236 | 0 |
| ALOX12 | ALOX12 | P18054 | Polyunsaturated fatty acid lipoxygenase ALOX12 | chr17 | GO:0061041 | Not Cancer Driver | No | 73 | 0.11 | 73 | 12 | 0.164 | 0 |
| ALOX5 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0061041 | Not Cancer Driver | No | 129 | 0.191 | 16 | 2 | 0.125 | 0 |
| ANO6_ENST00000320560 | ANO6 | Q4KMQ2 | Anoctamin-6 | chr12 | GO:0061041 | Not Cancer Driver | No | 134 | 0.147 | 80 | 11 | 0.138 | 0 |
| APCS | APCS | P02743 | Serum amyloid P-component | chr1 | GO:0061041 | Not Cancer Driver | No | 73 | 0.327 | 0 | 0 | 0.0 | 0 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0061041 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| APOH | APOH | P02749 | Beta-2-glycoprotein 1 | chr17 | GO:0061041 | Not Cancer Driver | No | 67 | 0.194 | 0 | 0 | 0.0 | 0 |
| C1QTNF1_ENST00000581774 | C1QTNF1 | Q9BXJ1 | Complement C1q tumor necrosis factor-related protein 1 | chr17 | GO:0061041 | Not Cancer Driver | No | 61 | 0.217 | 96 | 17 | 0.177 | 0 |
| CADM4 | CADM4 | Q8NFZ8 | Cell adhesion molecule 4 | chr19 | GO:0061041 | Not Cancer Driver | No | 48 | 0.124 | 94 | 9 | 0.096 | 0 |
| CASK_ENST00000378163 | CASK | O14936 | Peripheral plasma membrane protein CASK | chrX | GO:0061041 | Not Cancer Driver | No | 118 | 0.127 | 285 | 45 | 0.158 | 4 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0061041 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CD109 | CD109 | Q6YHK3 | CD109 antigen | chr6 | GO:0061041 | Not Cancer Driver | No | 204 | 0.141 | 54 | 11 | 0.204 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0061041 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CD9 | CD9 | P21926 | CD9 antigen | chr12 | GO:0061041 | Not Cancer Driver | No | 22 | 0.096 | 0 | 0 | 0.0 | 0 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0061041 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| CLASP1_ENST00000646274 | CLASP1 | Q7Z460 | CLIP-associating protein 1 | chr2 | GO:0061041 | Not Cancer Driver | No | 163 | 0.106 | 642 | 70 | 0.109 | 0 |
| CLASP2 | CLASP2 | O75122 | CLIP-associating protein 2 | chr3 | GO:0061041 | Not Cancer Driver | No | 158 | 0.122 | 676 | 94 | 0.139 | 0 |
| CLDN19 | CLDN19 | Q8N6F1 | Claudin-19 | chr1 | GO:0061041 | Not Cancer Driver | No | 27 | 0.121 | 20 | 2 | 0.1 | 3 |
| CLDN3 | CLDN3 | O15551 | Claudin-3 | chr7 | GO:0061041 | Not Cancer Driver | No | 12 | 0.055 | 0 | 0 | 0.0 | 0 |
| CPB2_ENST00000645658 | CPB2 | Q96IY4 | Carboxypeptidase B2 | chr13 | GO:0061041 | Not Cancer Driver | No | 59 | 0.139 | 2 | 0 | 0.0 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0061041 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0061041 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
| DMTN_ENST00000358242 | DMTN | Q08495 | Dematin | chr8 | GO:0061041 | Not Cancer Driver | No | 53 | 0.131 | 348 | 46 | 0.132 | 0 |
| ENPP4 | ENPP4 | Q9Y6X5 | Bis(5'-adenosyl)-triphosphatase ENPP4 | chr6 | GO:0061041 | Not Cancer Driver | No | 79 | 0.174 | 20 | 4 | 0.2 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0061041 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| EPPK1 | EPPK1 | P58107 | Epiplakin | chr8 | GO:0061041 | Not Cancer Driver | No | 417 | 0.082 | 1336 | 67 | 0.05 | 0 |
| F11 | F11 | P03951 | Coagulation factor XI | chr4 | GO:0061041 | Not Cancer Driver | No | 108 | 0.173 | 1 | 0 | 0.0 | 58 |
| F12 | F12 | P00748 | Coagulation factor XII | chr5 | GO:0061041 | Not Cancer Driver | No | 53 | 0.086 | 104 | 9 | 0.087 | 13 |
| F2 | F2 | P00734 | Prothrombin | chr11 | GO:0061041 | Not Cancer Driver | No | 115 | 0.185 | 97 | 25 | 0.258 | 10 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0061041 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0061041 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| F3 | F3 | P13726 | Tissue factor | chr1 | GO:0061041 | Not Cancer Driver | No | 28 | 0.095 | 61 | 7 | 0.115 | 0 |
| F7 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0061041 | Not Cancer Driver | No | 74 | 0.159 | 50 | 7 | 0.14 | 108 |
| FAM19A5 | TAFA5 | Q7Z5A7 | Chemokine-like protein TAFA-5 | chr22 | GO:0061041 | Not Cancer Driver | No | 31 | 0.235 | 27 | 6 | 0.222 | 0 |
| FAP | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0061041 | Not Cancer Driver | No | 158 | 0.208 | 6 | 2 | 0.333 | 0 |
| FERMT1 | FERMT1 | Q9BQL6 | Fermitin family homolog 1 | chr20 | GO:0061041 | Not Cancer Driver | No | 100 | 0.148 | 65 | 8 | 0.123 | 2 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0061041 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0061041 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0061041 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0061041 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0061041 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| FOXA2_ENST00000377115 | FOXA2 | Q9Y261 | Hepatocyte nuclear factor 3-beta | chr20 | GO:0061041 | Compendium | Yes | 70 | 0.153 | 258 | 34 | 0.132 | 0 |
| FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0061041 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
| GP1BA | GP1BA | P07359 | Platelet glycoprotein Ib alpha chain | chr17 | GO:0061041 | Not Cancer Driver | No | 65 | 0.1 | 247 | 18 | 0.073 | 9 |
| HPSE | HPSE | Q9Y251 | Heparanase | chr4 | GO:0061041 | Not Cancer Driver | No | 90 | 0.166 | 16 | 2 | 0.125 | 0 |
| HRG | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0061041 | Not Cancer Driver | No | 121 | 0.23 | 277 | 75 | 0.271 | 2 |
| KLKB1 | KLKB1 | P03952 | Plasma kallikrein | chr4 | GO:0061041 | Not Cancer Driver | No | 117 | 0.183 | 24 | 1 | 0.042 | 3 |
| KRT1 | KRT1 | P04264 | Keratin, type II cytoskeletal 1 | chr12 | GO:0061041 | Not Cancer Driver | No | 133 | 0.207 | 426 | 98 | 0.23 | 20 |
| MMRN1 | MMRN1 | Q13201 | Multimerin-1 | chr4 | GO:0061041 | Not Cancer Driver | No | 241 | 0.196 | 373 | 75 | 0.201 | 0 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0061041 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| MYOZ1 | MYOZ1 | Q9NP98 | Myozenin-1 | chr10 | GO:0061041 | Not Cancer Driver | No | 49 | 0.164 | 223 | 39 | 0.175 | 0 |
| NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0061041 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0061041 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0061041 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0061041 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0061041 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
| PHLDB2 | PHLDB2 | Q86SQ0 | Pleckstrin homology-like domain family B member 2 | chr3 | GO:0061041 | Not Cancer Driver | No | 235 | 0.188 | 1030 | 190 | 0.184 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0061041 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PLAU | PLAU | P00749 | Urokinase-type plasminogen activator | chr10 | GO:0061041 | Not Cancer Driver | No | 59 | 0.137 | 10 | 0 | 0.0 | 0 |
| PLG | PLG | P00747 | Plasminogen | chr6 | GO:0061041 | Not Cancer Driver | No | 242 | 0.299 | 230 | 64 | 0.278 | 9 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | GO:0061041 | Not Cancer Driver | No | 24 | 0.121 | 30 | 4 | 0.133 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0061041 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PRKG1_ENST00000401604 | PRKG1 | Q13976 | cGMP-dependent protein kinase 1 | chr10 | GO:0061041 | Not Cancer Driver | No | 167 | 0.249 | 93 | 22 | 0.237 | 1 |
| PROS1 | PROS1 | P07225 | Vitamin K-dependent protein S | chr3 | GO:0061041 | Not Cancer Driver | No | 178 | 0.263 | 11 | 3 | 0.273 | 89 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0061041 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RREB1_ENST00000349384 | RREB1 | Q92766 | Ras-responsive element-binding protein 1 | chr6 | GO:0061041 | Not Cancer Driver | No | 213 | 0.126 | 1152 | 144 | 0.125 | 0 |
| SERPINB2_ENST00000299502 | SERPINB2 | P05120 | Plasminogen activator inhibitor 2 | chr18 | GO:0061041 | Not Cancer Driver | No | 100 | 0.241 | 29 | 7 | 0.241 | 0 |
| SERPINC1 | SERPINC1 | P01008 | Antithrombin-III | chr1 | GO:0061041 | Not Cancer Driver | No | 84 | 0.181 | 29 | 8 | 0.276 | 84 |
| SERPINE1 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0061041 | Not Cancer Driver | No | 78 | 0.194 | 7 | 2 | 0.286 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0061041 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0061041 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
| SERPING1 | SERPING1 | P05155 | Plasma protease C1 inhibitor | chr11 | GO:0061041 | Not Cancer Driver | No | 74 | 0.148 | 113 | 13 | 0.115 | 40 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0061041 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | GO:0061041 | Not Cancer Driver | No | 141 | 0.116 | 297 | 18 | 0.061 | 8 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0061041 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMOC2_ENST00000356284 | SMOC2 | Q9H3U7 | SPARC-related modular calcium-binding protein 2 | chr6 | GO:0061041 | Not Cancer Driver | No | 82 | 0.184 | 216 | 52 | 0.241 | 0 |
| SRSF6 | SRSF6 | Q13247 | Serine/arginine-rich splicing factor 6 | chr20 | GO:0061041 | Not Cancer Driver | No | 69 | 0.201 | 259 | 49 | 0.189 | 0 |
| ST3GAL4_ENST00000534083 | ST3GAL4 | Q11206 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 | chr11 | GO:0061041 | Not Cancer Driver | No | 31 | 0.093 | 3 | 2 | 0.667 | 0 |
| TBXA2R_ENST00000375190 | TBXA2R | P21731 | Thromboxane A2 receptor | chr19 | GO:0061041 | Not Cancer Driver | No | 47 | 0.137 | 17 | 4 | 0.235 | 1 |
| THBD | THBD | P07204 | Thrombomodulin | chr20 | GO:0061041 | Not Cancer Driver | No | 39 | 0.068 | 51 | 3 | 0.059 | 9 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0061041 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0061041 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0061041 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TNFRSF12A | TNFRSF12A | Q9NP84 | Tumor necrosis factor receptor superfamily member 12A | chr16 | GO:0061041 | Not Cancer Driver | No | 8 | 0.062 | 0 | 0 | 0.0 | 0 |
| UBASH3B | UBASH3B | Q8TF42 | Ubiquitin-associated and SH3 domain-containing protein B | chr11 | GO:0061041 | Not Cancer Driver | No | 86 | 0.133 | 73 | 6 | 0.082 | 0 |
| USF1 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0061041 | Not Cancer Driver | No | 52 | 0.168 | 271 | 44 | 0.162 | 0 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0061041 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
| VKORC1 | VKORC1 | Q9BQB6 | Vitamin K epoxide reductase complex subunit 1 | chr16 | GO:0061041 | Not Cancer Driver | No | 14 | 0.086 | 3 | 0 | 0.0 | 19 |
| WFDC1_ENST00000568638 | WFDC1 | Q9HC57 | WAP four-disulfide core domain protein 1 | chr16 | GO:0061041 | Not Cancer Driver | No | 17 | 0.077 | 92 | 6 | 0.065 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0061041 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0061041 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |