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Total number of protein in "GO:0052689" GO term:  118

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADACL2 AADACL2 Q6P093 Arylacetamide deacetylase-like 2 chr3 GO:0052689 Not Cancer Driver No 102 0.254 5 3 0.6 0
AADACL3 AADACL3 Q5VUY0 Arylacetamide deacetylase-like 3 chr1 GO:0052689 Not Cancer Driver No 67 0.165 5 1 0.2 0
AADACL4 AADACL4 Q5VUY2 Arylacetamide deacetylase-like 4 chr1 GO:0052689 Not Cancer Driver No 91 0.224 0 0 0.0 0
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0052689 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0052689 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0052689 Not Cancer Driver No 40 0.097 157 20 0.127 0
ABHD1 ABHD1 Q96SE0 Protein ABHD1 chr2 GO:0052689 Not Cancer Driver No 43 0.106 26 3 0.115 0
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 GO:0052689 Not Cancer Driver No 38 0.124 7 2 0.286 0
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 GO:0052689 Not Cancer Driver No 50 0.107 41 3 0.073 0
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0052689 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABHD3 ABHD3 Q8WU67 Phospholipase ABHD3 chr18 GO:0052689 Not Cancer Driver No 43 0.105 0 0 0.0 0
ABHD4 ABHD4 Q8TB40 (Lyso)-N-acylphosphatidylethanolamine lipase chr14 GO:0052689 Not Cancer Driver No 46 0.135 39 5 0.128 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0052689 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABHD8 ABHD8 Q96I13 Protein ABHD8 chr19 GO:0052689 Not Cancer Driver No 58 0.132 134 19 0.142 0
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 GO:0052689 Not Cancer Driver No 81 0.132 64 8 0.125 0
ACOT1 ACOT1 Q86TX2 Acyl-coenzyme A thioesterase 1 chr14 GO:0052689 Not Cancer Driver No 28 0.067 22 0 0.0 0
ACOT11 ACOT11 Q8WXI4 Acyl-coenzyme A thioesterase 11 chr1 GO:0052689 Not Cancer Driver No 88 0.145 110 19 0.173 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0052689 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACOT2 ACOT2 P49753 Acyl-coenzyme A thioesterase 2, mitochondrial chr14 GO:0052689 Not Cancer Driver No 49 0.101 35 5 0.143 0
ACOT4 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 GO:0052689 Not Cancer Driver No 53 0.126 13 1 0.077 0
ACOT6_ENST00000645972 ACOT6 Q3I5F7 Acyl-coenzyme A thioesterase 6 chr14 GO:0052689 Not Cancer Driver No 30 0.071 18 0 0.0 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0052689 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:0052689 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX GO:0052689 Not Cancer Driver No 45 0.103 45 3 0.067 0
AL121900.2 AL121900.2 A0A087WZV9 D-aminoacyl-tRNA deacylase (Fragment) chr20 GO:0052689 Not Cancer Driver No 41 0.184 77 19 0.247 0
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 GO:0052689 Census Yes 60 0.116 44 1 0.023 0
AOAH_ENST00000617537 AOAH P28039 Acyloxyacyl hydrolase chr7 GO:0052689 Not Cancer Driver No 111 0.193 68 10 0.147 0
APMAP APMAP Q9HDC9 Adipocyte plasma membrane-associated protein chr20 GO:0052689 Not Cancer Driver No 66 0.159 72 11 0.153 0
ASPG ASPG Q86U10 60 kDa lysophospholipase chr14 GO:0052689 Not Cancer Driver No 68 0.119 76 13 0.171 0
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 GO:0052689 Not Cancer Driver No 88 0.211 10 4 0.4 1
BCHE BCHE P06276 Cholinesterase chr3 GO:0052689 Not Cancer Driver No 185 0.307 14 4 0.286 38
BPHL BPHL Q86WA6 Valacyclovir hydrolase chr6 GO:0052689 Not Cancer Driver No 35 0.12 12 1 0.083 0
CA1_ENST00000431316 CA1 P00915 Carbonic anhydrase 1 chr8 GO:0052689 Not Cancer Driver No 50 0.192 100 18 0.18 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0052689 Not Cancer Driver No 41 0.158 55 8 0.145 4
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0052689 Not Cancer Driver No 101 0.134 280 40 0.143 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0052689 Not Cancer Driver No 138 0.243 41 2 0.049 0
CES3 CES3 Q6UWW8 Carboxylesterase 3 chr16 GO:0052689 Not Cancer Driver No 94 0.165 112 13 0.116 0
CES5A_ENST00000290567 CES5A Q6NT32 Carboxylesterase 5A chr16 GO:0052689 Not Cancer Driver No 115 0.2 18 2 0.111 0
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0052689 Not Cancer Driver No 45 0.098 119 4 0.034 0
DPH7 DPH7 Q9BTV6 Diphthine methyltransferase chr9 GO:0052689 Not Cancer Driver No 38 0.084 107 10 0.093 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 GO:0052689 Not Cancer Driver No 45 0.215 93 26 0.28 0
DTD2_ENST00000356180 DTD2 Q96FN9 D-aminoacyl-tRNA deacylase 2 chr14 GO:0052689 Not Cancer Driver No 12 0.071 11 1 0.091 0
ESD ESD P10768 S-formylglutathione hydrolase chr13 GO:0052689 Not Cancer Driver No 33 0.117 4 0 0.0 0
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0052689 Not Cancer Driver No 96 0.121 39 3 0.077 2
HRASLS2 PLAAT2 Q9NWW9 Phospholipase A and acyltransferase 2 chr11 GO:0052689 Not Cancer Driver No 24 0.148 16 2 0.125 0
HRASLS5 PLAAT5 Q96KN8 Phospholipase A and acyltransferase 5 chr11 GO:0052689 Not Cancer Driver No 41 0.147 127 12 0.094 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0052689 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0052689 Not Cancer Driver No 149 0.147 145 22 0.152 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0052689 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0052689 Not Cancer Driver No 74 0.082 80 8 0.1 3
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0052689 Not Cancer Driver No 43 0.098 28 2 0.071 34
LIPA LIPA P38571 Lysosomal acid lipase/cholesteryl ester hydrolase chr10 GO:0052689 Not Cancer Driver No 44 0.11 12 1 0.083 4
LIPC_ENST00000356113 LIPC P11150 Hepatic triacylglycerol lipase chr15 GO:0052689 Not Cancer Driver No 91 0.182 17 3 0.176 2
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0052689 Not Cancer Driver No 123 0.114 496 65 0.131 0
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0052689 Not Cancer Driver No 90 0.18 59 7 0.119 0
LIPH LIPH Q8WWY8 Lipase member H chr3 GO:0052689 Not Cancer Driver No 71 0.157 32 8 0.25 2
LIPI_ENST00000536861 LIPI Q6XZB0 Lipase member I chr21 GO:0052689 Not Cancer Driver No 142 0.309 5 0 0.0 1
LIPK LIPK Q5VXJ0 Lipase member K chr10 GO:0052689 Not Cancer Driver No 44 0.11 0 0 0.0 0
LIPM LIPM Q5VYY2 Lipase member M chr10 GO:0052689 Not Cancer Driver No 18 0.043 13 0 0.0 0
LIPN LIPN Q5VXI9 Lipase member N chr10 GO:0052689 Not Cancer Driver No 53 0.133 8 1 0.125 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0052689 Not Cancer Driver No 94 0.198 23 3 0.13 70
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0052689 Not Cancer Driver No 19 0.083 12 2 0.167 0
LYPLA2 LYPLA2 O95372 Acyl-protein thioesterase 2 chr1 GO:0052689 Not Cancer Driver No 22 0.095 13 2 0.154 0
LYPLAL1 LYPLAL1 Q5VWZ2 Lysophospholipase-like protein 1 chr1 GO:0052689 Not Cancer Driver No 30 0.127 2 0 0.0 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 GO:0052689 Not Cancer Driver No 28 0.136 105 13 0.124 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0052689 Not Cancer Driver No 117 0.133 22 1 0.045 4
NDST3 NDST3 O95803 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 chr4 GO:0052689 Not Cancer Driver No 186 0.213 9 1 0.111 0
NOTUM NOTUM Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM chr17 GO:0052689 Not Cancer Driver No 50 0.101 73 6 0.082 0
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0052689 Census Yes 25 0.109 43 1 0.023 0
PAFAH1B3_ENST00000262890 PAFAH1B3 Q15102 Platelet-activating factor acetylhydrolase IB subunit alpha1 chr19 GO:0052689 Not Cancer Driver No 15 0.065 76 3 0.039 0
PAFAH2_ENST00000374284 PAFAH2 Q99487 Platelet-activating factor acetylhydrolase 2, cytoplasmic chr1 GO:0052689 Not Cancer Driver No 62 0.158 41 7 0.171 0
PGAP1 PGAP1 Q75T13 GPI inositol-deacylase chr2 GO:0052689 Not Cancer Driver No 127 0.138 21 7 0.333 0
PGLS PGLS O95336 6-phosphogluconolactonase chr19 GO:0052689 Not Cancer Driver No 20 0.078 36 4 0.111 0
PLA1A PLA1A Q53H76 Phospholipase A1 member A chr3 GO:0052689 Not Cancer Driver No 94 0.206 10 0 0.0 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0052689 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G12A PLA2G12A Q9BZM1 Group XIIA secretory phospholipase A2 chr4 GO:0052689 Not Cancer Driver No 18 0.095 0 0 0.0 0
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 GO:0052689 Not Cancer Driver No 61 0.148 11 3 0.273 0
PLA2G16 PLAAT3 P53816 Phospholipase A and acyltransferase 3 chr11 GO:0052689 Not Cancer Driver No 16 0.099 13 1 0.077 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0052689 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0052689 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G2C_ENST00000429261 PLA2G2C Q5R387 Putative inactive group IIC secretory phospholipase A2 chr1 GO:0052689 Not Cancer Driver No 18 0.121 10 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0052689 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G2E PLA2G2E Q9NZK7 Group IIE secretory phospholipase A2 chr1 GO:0052689 Not Cancer Driver No 33 0.232 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0052689 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0052689 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4B_ENST00000458483 PLA2G4B P0C869 Cytosolic phospholipase A2 beta chr15 GO:0052689 Not Cancer Driver No 88 0.113 144 18 0.125 0
PLA2G4C_ENST00000599921 PLA2G4C Q9UP65 Cytosolic phospholipase A2 gamma chr19 GO:0052689 Not Cancer Driver No 107 0.198 62 9 0.145 0
PLA2G4D PLA2G4D Q86XP0 Cytosolic phospholipase A2 delta chr15 GO:0052689 Not Cancer Driver No 115 0.141 172 17 0.099 0
PLA2G4E PLA2G4E Q3MJ16 Cytosolic phospholipase A2 epsilon chr15 GO:0052689 Not Cancer Driver No 71 0.082 123 6 0.049 0
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0052689 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0052689 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0052689 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0052689 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0052689 Not Cancer Driver No 223 0.153 399 57 0.143 0
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0052689 Not Cancer Driver No 124 0.267 32 11 0.344 1
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0052689 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0052689 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0052689 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPLA4_ENST00000444736 PNPLA4 P41247 Patatin-like phospholipase domain-containing protein 4 chrX GO:0052689 Not Cancer Driver No 41 0.162 3 0 0.0 0
PNPLA6 PNPLA6 Q8IY17 Patatin-like phospholipase domain-containing protein 6 chr19 GO:0052689 Not Cancer Driver No 171 0.124 367 49 0.134 18
PNPLA7_ENST00000277531 PNPLA7 Q6ZV29 Patatin-like phospholipase domain-containing protein 7 chr9 GO:0052689 Not Cancer Driver No 180 0.137 283 35 0.124 0
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0052689 Not Cancer Driver No 94 0.12 140 18 0.129 0
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 GO:0052689 Not Cancer Driver No 80 0.225 10 9 0.9 0
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 GO:0052689 Not Cancer Driver No 46 0.13 13 3 0.231 0
PON3 PON3 Q15166 Serum paraoxonase/lactonase 3 chr7 GO:0052689 Not Cancer Driver No 69 0.195 32 6 0.188 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0052689 Not Cancer Driver No 35 0.091 146 9 0.062 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0052689 Not Cancer Driver No 46 0.205 13 4 0.308 0
PTRH1 PTRH1 Q86Y79 Probable peptidyl-tRNA hydrolase chr9 GO:0052689 Not Cancer Driver No 18 0.084 52 6 0.115 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0052689 Not Cancer Driver No 14 0.078 19 2 0.105 1
PTRHD1 PTRHD1 Q6GMV3 Putative peptidyl-tRNA hydrolase PTRHD1 chr2 GO:0052689 Not Cancer Driver No 12 0.086 22 2 0.091 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0052689 Not Cancer Driver No 25 0.152 7 1 0.143 0
RGN RGN Q15493 Regucalcin chrX GO:0052689 Not Cancer Driver No 38 0.127 14 3 0.214 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0052689 Not Cancer Driver No 109 0.205 10 1 0.1 44
SIAE SIAE Q9HAT2 Sialate O-acetylesterase chr11 GO:0052689 Not Cancer Driver No 53 0.101 10 3 0.3 9
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0052689 Not Cancer Driver No 112 0.156 53 10 0.189 1
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0052689 Not Cancer Driver No 62 0.224 13 5 0.385 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0052689 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0052689 Not Cancer Driver No 111 0.104 253 21 0.083 3