Total number of protein in "GO:0051896" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0051896 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| BANK1 | BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | chr4 | GO:0051896 | Not Cancer Driver | No | 150 | 0.191 | 394 | 73 | 0.185 | 0 |
| BTN2A2 | BTN2A2 | Q8WVV5 | Butyrophilin subfamily 2 member A2 | chr6 | GO:0051896 | Not Cancer Driver | No | 92 | 0.176 | 24 | 2 | 0.083 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0051896 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CAVIN3 | CAVIN3 | Q969G5 | Caveolae-associated protein 3 | chr11 | GO:0051896 | Not Cancer Driver | No | 22 | 0.084 | 234 | 19 | 0.081 | 0 |
| CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0051896 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
| CRYBA1 | CRYBA1 | P05813 | Beta-crystallin A3 | chr17 | GO:0051896 | Not Cancer Driver | No | 29 | 0.135 | 52 | 11 | 0.212 | 0 |
| DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0051896 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0051896 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0051896 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0051896 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0051896 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0051896 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
| FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0051896 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0051896 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0051896 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GRM2 | GRM2 | Q14416 | Metabotropic glutamate receptor 2 | chr3 | GO:0051896 | Not Cancer Driver | No | 143 | 0.164 | 24 | 3 | 0.125 | 0 |
| HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0051896 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0051896 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| INPP5F | INPP5F | Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 | chr10 | GO:0051896 | Not Cancer Driver | No | 138 | 0.122 | 394 | 45 | 0.114 | 0 |
| INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0051896 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
| LEMD2_ENST00000614475 | LEMD2 | Q8NC56 | LEM domain-containing protein 2 | chr6 | GO:0051896 | Not Cancer Driver | No | 44 | 0.087 | 211 | 4 | 0.019 | 2 |
| MAGI2 | MAGI2 | Q86UL8 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | chr7 | GO:0051896 | Not Cancer Driver | No | 305 | 0.21 | 1086 | 201 | 0.185 | 0 |
| MSTN | MSTN | O14793 | Growth/differentiation factor 8 | chr2 | GO:0051896 | Not Cancer Driver | No | 68 | 0.181 | 64 | 11 | 0.172 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0051896 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0051896 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0051896 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| NOP53 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:0051896 | Not Cancer Driver | No | 59 | 0.123 | 391 | 41 | 0.105 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0051896 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NTRK2_ENST00000323115 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0051896 | Not Cancer Driver | No | 155 | 0.189 | 117 | 18 | 0.154 | 1 |
| NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0051896 | Census, Compendium | Yes | 249 | 0.297 | 57 | 21 | 0.368 | 0 |
| OTUD3 | OTUD3 | Q5T2D3 | OTU domain-containing protein 3 | chr1 | GO:0051896 | Not Cancer Driver | No | 43 | 0.108 | 280 | 25 | 0.089 | 0 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0051896 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
| PHLDA3 | PHLDA3 | Q9Y5J5 | Pleckstrin homology-like domain family A member 3 | chr1 | GO:0051896 | Not Cancer Driver | No | 20 | 0.157 | 0 | 0 | 0.0 | 0 |
| PHLPP1 | PHLPP1 | O60346 | PH domain leucine-rich repeat-containing protein phosphatase 1 | chr18 | GO:0051896 | Not Cancer Driver | No | 134 | 0.078 | 744 | 29 | 0.039 | 0 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0051896 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PKHD1 | PKHD1 | P08F94 | Fibrocystin | chr6 | GO:0051896 | Not Cancer Driver | No | 778 | 0.191 | 413 | 81 | 0.196 | 93 |
| PLEKHA1 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0051896 | Not Cancer Driver | No | 61 | 0.151 | 191 | 32 | 0.168 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:0051896 | Not Cancer Driver | No | 63 | 0.135 | 68 | 9 | 0.132 | 0 |
| PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | GO:0051896 | Not Cancer Driver | No | 41 | 0.133 | 12 | 1 | 0.083 | 8 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0051896 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0051896 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0051896 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RCN3 | RCN3 | Q96D15 | Reticulocalbin-3 | chr19 | GO:0051896 | Not Cancer Driver | No | 44 | 0.134 | 243 | 39 | 0.16 | 0 |
| RICTOR_ENST00000357387 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0051896 | Not Cancer Driver | No | 212 | 0.124 | 366 | 50 | 0.137 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0051896 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| RRAS | RRAS | P10301 | Ras-related protein R-Ras | chr19 | GO:0051896 | Not Cancer Driver | No | 25 | 0.115 | 71 | 6 | 0.085 | 0 |
| SESN3 | SESN3 | P58005 | Sestrin-3 | chr11 | GO:0051896 | Not Cancer Driver | No | 84 | 0.171 | 44 | 4 | 0.091 | 0 |
| SFRP5 | SFRP5 | Q5T4F7 | Secreted frizzled-related protein 5 | chr10 | GO:0051896 | Not Cancer Driver | No | 26 | 0.082 | 7 | 3 | 0.429 | 0 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0051896 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0051896 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0051896 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0051896 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| TPTE2 | TPTE2 | Q6XPS3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | chr13 | GO:0051896 | Not Cancer Driver | No | 210 | 0.402 | 33 | 13 | 0.394 | 0 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0051896 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0051896 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |