Total number of protein in "GO:0051216" GO term: 72
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0051216 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| BGN | BGN | P21810 | Biglycan | chrX | GO:0051216 | Not Cancer Driver | No | 63 | 0.171 | 26 | 3 | 0.115 | 2 |
| BMP3 | BMP3 | P12645 | Bone morphogenetic protein 3 | chr4 | GO:0051216 | Not Cancer Driver | No | 120 | 0.254 | 147 | 48 | 0.327 | 0 |
| BMP5 | BMP5 | P22003 | Bone morphogenetic protein 5 | chr6 | GO:0051216 | Census | Yes | 163 | 0.359 | 112 | 62 | 0.554 | 0 |
| BMP6 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0051216 | Not Cancer Driver | No | 95 | 0.185 | 226 | 51 | 0.226 | 0 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0051216 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BMP8A | BMP8A | Q7Z5Y6 | Bone morphogenetic protein 8A | chr1 | GO:0051216 | Not Cancer Driver | No | 26 | 0.065 | 93 | 2 | 0.022 | 0 |
| BMP8B | BMP8B | P34820 | Bone morphogenetic protein 8B | chr1 | GO:0051216 | Not Cancer Driver | No | 21 | 0.052 | 90 | 3 | 0.033 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:0051216 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CHI3L1 | CHI3L1 | P36222 | Chitinase-3-like protein 1 | chr1 | GO:0051216 | Not Cancer Driver | No | 66 | 0.172 | 24 | 5 | 0.208 | 0 |
| CHRDL2_ENST00000376332 | CHRDL2 | Q6WN34 | Chordin-like protein 2 | chr11 | GO:0051216 | Not Cancer Driver | No | 61 | 0.142 | 104 | 20 | 0.192 | 0 |
| CNMD | CNMD | O75829 | Leukocyte cell-derived chemotaxin 1 | chr13 | GO:0051216 | Not Cancer Driver | No | 52 | 0.156 | 63 | 13 | 0.206 | 0 |
| COL11A2_ENST00000341947 | COL11A2 | P13942 | Collagen alpha-2(XI) chain | chr6 | GO:0051216 | Not Cancer Driver | No | 286 | 0.165 | 1471 | 246 | 0.167 | 7 |
| COL1A1 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0051216 | Census, Compendium | Yes | 247 | 0.169 | 1212 | 214 | 0.177 | 148 |
| COL2A1 | COL2A1 | P02458 | Collagen alpha-1(II) chain | chr12 | GO:0051216 | Census | Yes | 258 | 0.174 | 1215 | 207 | 0.17 | 64 |
| COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0051216 | Not Cancer Driver | No | 97 | 0.128 | 306 | 52 | 0.17 | 61 |
| CREB3L2 | CREB3L2 | Q70SY1 | Cyclic AMP-responsive element-binding protein 3-like protein 2 | chr7 | GO:0051216 | Census | Yes | 61 | 0.117 | 364 | 46 | 0.126 | 0 |
| CSGALNACT1_ENST00000332246 | CSGALNACT1 | Q8TDX6 | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 | chr8 | GO:0051216 | Not Cancer Driver | No | 91 | 0.171 | 131 | 28 | 0.214 | 0 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | GO:0051216 | Not Cancer Driver | No | 34 | 0.108 | 181 | 23 | 0.127 | 0 |
| DLX2 | DLX2 | Q07687 | Homeobox protein DLX-2 | chr2 | GO:0051216 | Not Cancer Driver | No | 46 | 0.14 | 262 | 38 | 0.145 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0051216 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EPYC | EPYC | Q99645 | Epiphycan | chr12 | GO:0051216 | Not Cancer Driver | No | 61 | 0.189 | 80 | 20 | 0.25 | 0 |
| ESRRA_ENST00000000442 | ESRRA | P11474 | Steroid hormone receptor ERR1 | chr11 | GO:0051216 | Compendium | Yes | 37 | 0.087 | 101 | 9 | 0.089 | 0 |
| EVC | EVC | P57679 | Ellis-van Creveld syndrome protein | chr4 | GO:0051216 | Not Cancer Driver | No | 143 | 0.144 | 373 | 60 | 0.161 | 4 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0051216 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0051216 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0051216 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| HES5 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0051216 | Not Cancer Driver | No | 1 | 0.006 | 73 | 0 | 0.0 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0051216 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HOXA11 | HOXA11 | P31270 | Homeobox protein Hox-A11 | chr7 | GO:0051216 | Census, Compendium | Yes | 37 | 0.118 | 205 | 26 | 0.127 | 0 |
| HOXA3_ENST00000396352 | HOXA3 | O43365 | Homeobox protein Hox-A3 | chr7 | GO:0051216 | Not Cancer Driver | No | 86 | 0.194 | 417 | 84 | 0.201 | 0 |
| HOXB3_ENST00000498678 | HOXB3 | P14651 | Homeobox protein Hox-B3 | chr17 | GO:0051216 | Not Cancer Driver | No | 74 | 0.172 | 398 | 66 | 0.166 | 0 |
| HOXC4 | HOXC4 | P09017 | Homeobox protein Hox-C4 | chr12 | GO:0051216 | Not Cancer Driver | No | 40 | 0.152 | 227 | 33 | 0.145 | 0 |
| HOXD3 | HOXD3 | P31249 | Homeobox protein Hox-D3 | chr2 | GO:0051216 | Not Cancer Driver | No | 68 | 0.157 | 354 | 64 | 0.181 | 0 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0051216 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0051216 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| HYAL3 | HYAL3 | O43820 | Hyaluronidase-3 | chr3 | GO:0051216 | Not Cancer Driver | No | 48 | 0.115 | 10 | 0 | 0.0 | 0 |
| IFT80 | IFT80 | Q9P2H3 | Intraflagellar transport protein 80 homolog | chr3 | GO:0051216 | Not Cancer Driver | No | 117 | 0.151 | 21 | 2 | 0.095 | 2 |
| IL17F | IL17F | Q96PD4 | Interleukin-17F | chr6 | GO:0051216 | Not Cancer Driver | No | 42 | 0.258 | 34 | 11 | 0.324 | 1 |
| ITGB8 | ITGB8 | P26012 | Integrin beta-8 | chr7 | GO:0051216 | Not Cancer Driver | No | 126 | 0.164 | 26 | 3 | 0.115 | 0 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0051216 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MATN3 | MATN3 | O15232 | Matrilin-3 | chr2 | GO:0051216 | Not Cancer Driver | No | 50 | 0.103 | 85 | 7 | 0.082 | 16 |
| MKKS | MKKS | Q9NPJ1 | McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin | chr20 | GO:0051216 | Not Cancer Driver | No | 56 | 0.098 | 6 | 1 | 0.167 | 22 |
| MMP13 | MMP13 | P45452 | Collagenase 3 | chr11 | GO:0051216 | Not Cancer Driver | No | 113 | 0.24 | 59 | 16 | 0.271 | 5 |
| NOG | NOG | Q13253 | Noggin | chr17 | GO:0051216 | Not Cancer Driver | No | 22 | 0.095 | 86 | 9 | 0.105 | 20 |
| PBXIP1 | PBXIP1 | Q96AQ6 | Pre-B-cell leukemia transcription factor-interacting protein 1 | chr1 | GO:0051216 | Not Cancer Driver | No | 100 | 0.137 | 605 | 86 | 0.142 | 0 |
| PITX1_ENST00000506438 | PITX1 | P78337 | Pituitary homeobox 1 | chr5 | GO:0051216 | Not Cancer Driver | No | 37 | 0.118 | 191 | 20 | 0.105 | 1 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0051216 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PRRX1 | PRRX1 | P54821 | Paired mesoderm homeobox protein 1 | chr1 | GO:0051216 | Census, Compendium | Yes | 69 | 0.282 | 205 | 49 | 0.239 | 1 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0051216 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RARG | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0051216 | Not Cancer Driver | No | 82 | 0.181 | 164 | 24 | 0.146 | 0 |
| SATB2 | SATB2 | Q9UPW6 | DNA-binding protein SATB2 | chr2 | GO:0051216 | Not Cancer Driver | No | 164 | 0.224 | 412 | 100 | 0.243 | 0 |
| SHOX2_ENST00000441443 | SHOX2 | O60902 | Short stature homeobox protein 2 | chr3 | GO:0051216 | Not Cancer Driver | No | 67 | 0.202 | 200 | 40 | 0.2 | 0 |
| SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0051216 | Not Cancer Driver | No | 54 | 0.116 | 161 | 22 | 0.137 | 0 |
| SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0051216 | Not Cancer Driver | No | 44 | 0.095 | 172 | 11 | 0.064 | 0 |
| SNORC_ENST00000409533 | SNORC | Q6UX34 | Protein SNORC | chr2 | GO:0051216 | Not Cancer Driver | No | 2 | 0.017 | 63 | 1 | 0.016 | 0 |
| SOX5 | SOX5 | P35711 | Transcription factor SOX-5 | chr12 | GO:0051216 | Not Cancer Driver | No | 182 | 0.239 | 665 | 162 | 0.244 | 0 |
| SOX6_ENST00000528429 | SOX6 | P35712 | Transcription factor SOX-6 | chr11 | GO:0051216 | Not Cancer Driver | No | 130 | 0.157 | 744 | 118 | 0.159 | 0 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0051216 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0051216 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| SULF1_ENST00000458141 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0051216 | Not Cancer Driver | No | 246 | 0.282 | 269 | 71 | 0.264 | 0 |
| SULF2_ENST00000484875 | SULF2 | Q8IWU5 | Extracellular sulfatase Sulf-2 | chr20 | GO:0051216 | Not Cancer Driver | No | 145 | 0.167 | 142 | 18 | 0.127 | 0 |
| TAPT1 | TAPT1 | Q6NXT6 | Transmembrane anterior posterior transformation protein 1 homolog | chr4 | GO:0051216 | Not Cancer Driver | No | 47 | 0.083 | 131 | 12 | 0.092 | 1 |
| THBS3 | THBS3 | P49746 | Thrombospondin-3 | chr1 | GO:0051216 | Not Cancer Driver | No | 100 | 0.105 | 283 | 24 | 0.085 | 0 |
| TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0051216 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |
| TRIP11 | TRIP11 | Q15643 | Thyroid receptor-interacting protein 11 | chr14 | GO:0051216 | Census, Compendium | Yes | 218 | 0.11 | 1364 | 161 | 0.118 | 2 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0051216 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0051216 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0051216 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| ZBTB16_ENST00000392996 | ZBTB16 | Q05516 | Zinc finger and BTB domain-containing protein 16 | chr11 | GO:0051216 | Census, Compendium | Yes | 131 | 0.195 | 268 | 50 | 0.187 | 1 |
| ZEB1_ENST00000320985 | ZEB1 | P37275 | Zinc finger E-box-binding homeobox 1 | chr10 | GO:0051216 | Census, Compendium | Yes | 246 | 0.219 | 831 | 200 | 0.241 | 8 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0051216 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |