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Total number of protein in "GO:0051053" GO term:  75

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0051053 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0051053 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051053 Not Cancer Driver No 39 0.16 92 21 0.228 1
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0051053 Not Cancer Driver No 52 0.163 83 13 0.157 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0051053 Census, Compendium Yes 469 0.153 225 39 0.173 41
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 GO:0051053 Not Cancer Driver No 23 0.064 341 21 0.062 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0051053 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0051053 Compendium Yes 141 0.136 601 70 0.116 19
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0051053 Census, Compendium Yes 48 0.293 121 30 0.248 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0051053 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0051053 Not Cancer Driver No 58 0.122 86 16 0.186 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0051053 Not Cancer Driver No 142 0.117 103 8 0.078 9
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0051053 Not Cancer Driver No 24 0.153 128 19 0.148 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0051053 Not Cancer Driver No 157 0.207 641 134 0.209 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0051053 Not Cancer Driver No 57 0.136 167 24 0.144 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0051053 Not Cancer Driver No 47 0.142 113 18 0.159 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 GO:0051053 Not Cancer Driver No 67 0.108 425 48 0.113 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0051053 Not Cancer Driver No 83 0.215 10 1 0.1 0
DPPA3 DPPA3 Q6W0C5 Developmental pluripotency-associated protein 3 chr12 GO:0051053 Not Cancer Driver No 58 0.365 105 43 0.41 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0051053 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0051053 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0051053 Not Cancer Driver No 211 0.141 829 117 0.141 9
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0051053 Not Cancer Driver No 87 0.098 375 35 0.093 0
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0051053 Not Cancer Driver No 99 0.133 206 20 0.097 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0051053 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0051053 Not Cancer Driver No 38 0.088 186 16 0.086 10
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0051053 Census, Compendium Yes 111 0.251 364 87 0.239 2
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0051053 Not Cancer Driver No 120 0.206 242 43 0.178 0
GZMA GZMA P12544 Granzyme A chr5 GO:0051053 Not Cancer Driver No 70 0.267 5 1 0.2 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0051053 Census Yes 12 0.11 109 12 0.11 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0051053 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0051053 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0051053 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0051053 Not Cancer Driver No 59 0.112 335 37 0.11 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0051053 Not Cancer Driver No 109 0.256 40 10 0.25 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0051053 Census, Compendium Yes 446 0.112 3145 338 0.107 0
MEN1 MEN1 O00255 Menin chr11 GO:0051053 Census, Compendium Yes 73 0.119 228 15 0.066 90
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0051053 Census Yes 92 0.122 208 22 0.106 85
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0051053 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBN NBN O60934 Nibrin chr8 GO:0051053 Census Yes 90 0.119 417 54 0.129 1
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0051053 Not Cancer Driver No 22 0.1 44 4 0.091 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0051053 Not Cancer Driver No 10 0.079 82 6 0.073 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0051053 Not Cancer Driver No 16 0.076 6 0 0.0 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0051053 Not Cancer Driver No 37 0.107 71 12 0.169 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0051053 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0051053 Not Cancer Driver No 70 0.131 269 38 0.141 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0051053 Not Cancer Driver No 54 0.084 209 11 0.053 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0051053 Not Cancer Driver No 66 0.201 328 66 0.201 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0051053 Census, Compendium Yes 113 0.178 31 6 0.194 9
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0051053 Not Cancer Driver No 157 0.12 730 84 0.115 0
RGN RGN Q15493 Regucalcin chrX GO:0051053 Not Cancer Driver No 38 0.127 14 3 0.214 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0051053 Not Cancer Driver No 144 0.118 474 64 0.135 14
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0051053 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0051053 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0051053 Not Cancer Driver No 166 0.117 751 97 0.129 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0051053 Census Yes 53 0.099 130 11 0.085 1
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0051053 Not Cancer Driver No 41 0.111 27 2 0.074 2
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 GO:0051053 Not Cancer Driver No 13 0.102 108 6 0.056 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0051053 Not Cancer Driver No 6 0.049 8 4 0.5 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0051053 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0051053 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0051053 Not Cancer Driver No 28 0.07 310 16 0.052 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0051053 Not Cancer Driver No 87 0.104 331 39 0.118 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0051053 Not Cancer Driver No 55 0.084 280 26 0.093 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:0051053 Not Cancer Driver No 38 0.084 190 17 0.089 4
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0051053 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0051053 Not Cancer Driver No 117 0.1 255 24 0.094 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0051053 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0051053 Not Cancer Driver No 87 0.104 430 41 0.095 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0051053 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0051053 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0051053 Not Cancer Driver No 213 0.125 577 65 0.113 0
ZNF91 ZNF91 Q05481 Zinc finger protein 91 chr19 GO:0051053 Not Cancer Driver No 317 0.266 128 24 0.188 0
ZNF93 ZNF93 P35789 Zinc finger protein 93 chr19 GO:0051053 Compendium Yes 101 0.163 73 18 0.247 0
ZSCAN4_ENST00000612521 ZSCAN4 Q8NAM6 Zinc finger and SCAN domain-containing protein 4 chr19 GO:0051053 Not Cancer Driver No 108 0.249 249 58 0.233 0