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Total number of protein in "GO:0051051" GO term:  411

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0051051 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0051051 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0051051 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0051051 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCG5_ENST00000405322 ABCG5 Q9H222 ATP-binding cassette sub-family G member 5 chr2 GO:0051051 Not Cancer Driver No 77 0.118 43 8 0.186 6
ABCG8 ABCG8 Q9H221 ATP-binding cassette sub-family G member 8 chr2 GO:0051051 Not Cancer Driver No 137 0.204 40 8 0.2 10
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0051051 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0051051 Not Cancer Driver No 227 0.254 131 29 0.221 9
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0051051 Not Cancer Driver No 90 0.183 3 1 0.333 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0051051 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051051 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0051051 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0051051 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0051051 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0051051 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0051051 Not Cancer Driver No 41 0.178 2 0 0.0 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051051 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0051051 Census Yes 77 0.16 84 9 0.107 2
AL132671.2 AL132671.2 A0A0J9YVX5 Uncharacterized protein (Fragment) chr6 GO:0051051 Not Cancer Driver No 54 0.174 128 26 0.203 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0051051 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0051051 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANKRD13A ANKRD13A Q8IZ07 Ankyrin repeat domain-containing protein 13A chr12 GO:0051051 Not Cancer Driver No 54 0.092 167 16 0.096 0
ANKRD13B ANKRD13B Q86YJ7 Ankyrin repeat domain-containing protein 13B chr17 GO:0051051 Not Cancer Driver No 64 0.102 290 18 0.062 0
ANKRD13D ANKRD13D Q6ZTN6 Ankyrin repeat domain-containing protein 13D chr11 GO:0051051 Not Cancer Driver No 67 0.111 286 24 0.084 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0051051 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANO9 ANO9 A1A5B4 Anoctamin-9 chr11 GO:0051051 Not Cancer Driver No 108 0.138 64 6 0.094 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0051051 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0051051 Not Cancer Driver No 49 0.145 20 4 0.2 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0051051 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0051051 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0051051 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0051051 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOD APOD P05090 Apolipoprotein D chr3 GO:0051051 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0051051 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0051051 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0051051 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0051051 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0051051 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARFIP1 ARFIP1 P53367 Arfaptin-1 chr4 GO:0051051 Not Cancer Driver No 43 0.115 145 19 0.131 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 GO:0051051 Not Cancer Driver No 39 0.089 90 8 0.089 0
ARHGAP8 ARHGAP8 P85298 Rho GTPase-activating protein 8 chr22 GO:0051051 Not Cancer Driver No 65 0.14 75 13 0.173 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0051051 Not Cancer Driver No 26 0.138 0 0 0.0 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0051051 Not Cancer Driver No 69 0.131 17 2 0.118 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0051051 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG3 ATG3 Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 chr3 GO:0051051 Not Cancer Driver No 29 0.092 110 9 0.082 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0051051 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0051051 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0051051 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATP9A ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 GO:0051051 Not Cancer Driver No 175 0.167 69 18 0.261 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 GO:0051051 Not Cancer Driver No 146 0.111 1228 134 0.109 0
AVPR2_ENST00000337474 AVPR2 P30518 Vasopressin V2 receptor chrX GO:0051051 Not Cancer Driver No 58 0.156 56 7 0.125 84
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0051051 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0051051 Not Cancer Driver No 55 0.12 402 49 0.122 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0051051 Census Yes 96 0.124 384 49 0.128 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0051051 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0051051 Census, Compendium Yes 146 0.115 603 69 0.114 0
BEST3 BEST3 Q8N1M1 Bestrophin-3 chr12 GO:0051051 Not Cancer Driver No 161 0.241 266 72 0.271 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0051051 Not Cancer Driver No 65 0.11 456 42 0.092 5
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0051051 Not Cancer Driver No 26 0.065 93 2 0.022 0
C11orf65 MFI Q8NCR3 Protein MFI chr11 GO:0051051 Not Cancer Driver No 42 0.134 66 7 0.106 0
C4orf3_ENST00000504110 C4orf3 Q8WVX3 Uncharacterized protein C4orf3 chr4 GO:0051051 Not Cancer Driver No 11 0.167 18 5 0.278 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0051051 Not Cancer Driver No 31 0.091 43 5 0.116 0
CABP1 CABP1 Q9NZU7 Calcium-binding protein 1 chr12 GO:0051051 Not Cancer Driver No 31 0.084 271 14 0.052 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0051051 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0051051 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0051051 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0051051 Not Cancer Driver No 57 0.114 84 10 0.119 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0051051 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0051051 Not Cancer Driver No 74 0.185 75 16 0.213 4
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051051 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0051051 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBARP_ENST00000382477 CBARP Q8N350 Voltage-dependent calcium channel beta subunit-associated regulatory protein chr19 GO:0051051 Not Cancer Driver No 41 0.058 661 33 0.05 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0051051 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0051051 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0051051 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0051051 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0051051 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0051051 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0051051 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0051051 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0051051 Census Yes 31 0.105 185 20 0.108 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0051051 Not Cancer Driver No 82 0.238 52 11 0.212 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0051051 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0051051 Not Cancer Driver No 64 0.122 241 25 0.104 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0051051 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0051051 Not Cancer Driver No 27 0.138 70 12 0.171 0
CLIC2 CLIC2 O15247 Chloride intracellular channel protein 2 chrX GO:0051051 Not Cancer Driver No 46 0.186 58 6 0.103 1
CNIH2 CNIH2 Q6PI25 Protein cornichon homolog 2 chr11 GO:0051051 Not Cancer Driver No 20 0.125 0 0 0.0 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 GO:0051051 Not Cancer Driver No 35 0.113 166 23 0.139 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0051051 Not Cancer Driver No 129 0.273 9 1 0.111 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 GO:0051051 Not Cancer Driver No 21 0.111 17 0 0.0 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0051051 Not Cancer Driver No 51 0.111 126 15 0.119 1
CRBN CRBN Q96SW2 Protein cereblon chr3 GO:0051051 Not Cancer Driver No 52 0.118 76 10 0.132 1
CRH CRH P06850 Corticoliberin chr8 GO:0051051 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0051051 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0051051 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0051051 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0051051 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 GO:0051051 Not Cancer Driver No 34 0.197 42 11 0.262 10
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0051051 Not Cancer Driver No 22 0.126 59 11 0.186 4
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0051051 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTTNBP2NL CTTNBP2NL Q9P2B4 CTTNBP2 N-terminal-like protein chr1 GO:0051051 Not Cancer Driver No 82 0.128 559 78 0.14 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0051051 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYP4F2 CYP4F2 P78329 Cytochrome P450 4F2 chr19 GO:0051051 Not Cancer Driver No 136 0.262 17 3 0.176 0
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 GO:0051051 Not Cancer Driver No 49 0.096 7 2 0.286 0
DCANP1 DCANP1 Q8TF63 Dendritic cell nuclear protein 1 chr5 GO:0051051 Not Cancer Driver No 44 0.18 159 35 0.22 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0051051 Not Cancer Driver No 19 0.079 15 1 0.067 0
DERL3_ENST00000318109 DERL3 Q96Q80 Derlin-3 chr22 GO:0051051 Not Cancer Driver No 18 0.077 18 1 0.056 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0051051 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0051051 Not Cancer Driver No 53 0.131 348 46 0.132 0
DPH3 DPH3 Q96FX2 DPH3 homolog chr3 GO:0051051 Not Cancer Driver No 12 0.146 0 0 0.0 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0051051 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0051051 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0051051 Not Cancer Driver No 26 0.062 109 0 0.0 0
DYSF_ENST00000258104 DYSF O75923 Dysferlin chr2 GO:0051051 Not Cancer Driver No 467 0.225 329 64 0.195 55
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0051051 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0051051 Not Cancer Driver No 184 0.152 191 25 0.131 1
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0051051 Not Cancer Driver No 148 0.16 101 5 0.05 33
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0051051 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0051051 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0051051 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPPIN EPPIN O95925 Eppin chr20 GO:0051051 Not Cancer Driver No 18 0.135 0 0 0.0 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0051051 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERLEC1 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 GO:0051051 Not Cancer Driver No 54 0.112 134 17 0.127 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0051051 Not Cancer Driver No 29 0.111 34 5 0.147 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0051051 Not Cancer Driver No 73 0.172 19 2 0.105 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0051051 Not Cancer Driver No 15 0.111 4 4 1.0 0
FAM3D FAM3D Q96BQ1 Protein FAM3D chr3 GO:0051051 Not Cancer Driver No 43 0.192 16 4 0.25 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0051051 Census Yes 51 0.165 99 30 0.303 0
FER1L5 FER1L5 A0AVI2 Fer-1-like protein 5 chr2 GO:0051051 Not Cancer Driver No 154 0.075 200 11 0.055 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0051051 Not Cancer Driver No 100 0.148 65 8 0.123 2
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0051051 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0051051 Not Cancer Driver No 84 0.335 97 51 0.526 7
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0051051 Not Cancer Driver No 25 0.164 6 0 0.0 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0051051 Not Cancer Driver No 15 0.139 39 7 0.179 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0051051 Not Cancer Driver No 10 0.093 58 4 0.069 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0051051 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0051051 Not Cancer Driver No 56 0.148 194 20 0.103 20
FRMD4A FRMD4A Q9P2Q2 FERM domain-containing protein 4A chr10 GO:0051051 Not Cancer Driver No 122 0.117 666 72 0.108 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0051051 Not Cancer Driver No 150 0.156 142 17 0.12 0
GABRE GABRE P78334 Gamma-aminobutyric acid receptor subunit epsilon chrX GO:0051051 Not Cancer Driver No 133 0.263 73 19 0.26 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0051051 Not Cancer Driver No 69 0.154 34 6 0.176 2
GEM GEM P55040 GTP-binding protein GEM chr8 GO:0051051 Not Cancer Driver No 64 0.216 96 22 0.229 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0051051 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0051051 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0051051 Not Cancer Driver No 86 0.225 110 26 0.236 50
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0051051 Compendium Yes 50 0.141 24 0 0.0 0
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:0051051 Not Cancer Driver No 60 0.152 16 1 0.062 1
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 GO:0051051 Census Yes 56 0.121 263 34 0.129 0
GPM6B_ENST00000356942 GPM6B Q13491 Neuronal membrane glycoprotein M6-b chrX GO:0051051 Not Cancer Driver No 39 0.147 14 3 0.214 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0051051 Not Cancer Driver No 57 0.184 0 0 0.0 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0051051 Not Cancer Driver No 94 0.158 220 38 0.173 0
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0051051 Not Cancer Driver No 316 0.345 91 31 0.341 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0051051 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0051051 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0051051 Not Cancer Driver No 26 0.108 18 1 0.056 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 GO:0051051 Not Cancer Driver No 33 0.105 22 5 0.227 3
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0051051 Not Cancer Driver No 7 0.083 4 0 0.0 4
HCRT HCRT O43612 Orexin chr17 GO:0051051 Not Cancer Driver No 3 0.023 45 0 0.0 1
HECW1 HECW1 Q76N89 E3 ubiquitin-protein ligase HECW1 chr7 GO:0051051 Not Cancer Driver No 420 0.262 748 191 0.255 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 GO:0051051 Not Cancer Driver No 348 0.221 845 195 0.231 4
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0051051 Not Cancer Driver No 37 0.132 226 32 0.142 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0051051 Not Cancer Driver No 43 0.124 115 22 0.191 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0051051 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0051051 Not Cancer Driver No 84 0.095 112 12 0.107 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0051051 Not Cancer Driver No 46 0.16 81 13 0.16 0
HRH3 HRH3 Q9Y5N1 Histamine H3 receptor chr20 GO:0051051 Not Cancer Driver No 65 0.146 93 10 0.108 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0051051 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0051051 Not Cancer Driver No 105 0.223 44 8 0.182 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0051051 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051051 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0051051 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051051 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0051051 Not Cancer Driver No 205 0.295 77 19 0.247 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0051051 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0051051 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0051051 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0051051 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0051051 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0051051 Not Cancer Driver No 37 0.134 43 1 0.023 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0051051 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0051051 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0051051 Not Cancer Driver No 14 0.084 24 3 0.125 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0051051 Census Yes 153 0.146 92 9 0.098 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0051051 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0051051 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0051051 Not Cancer Driver No 21 0.115 12 2 0.167 5
KCNAB1 KCNAB1 Q14722 Voltage-gated potassium channel subunit beta-1 chr3 GO:0051051 Not Cancer Driver No 89 0.212 83 23 0.277 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0051051 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0051051 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0051051 Not Cancer Driver No 25 0.203 2 0 0.0 5
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 GO:0051051 Not Cancer Driver No 28 0.272 24 2 0.083 0
KCNE4 KCNE4 Q8WWG9 Potassium voltage-gated channel subfamily E member 4 chr2 GO:0051051 Not Cancer Driver No 26 0.118 94 18 0.191 0
KCNE5 KCNE5 Q9UJ90 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 chrX GO:0051051 Not Cancer Driver No 35 0.246 68 26 0.382 0
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0051051 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0051051 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNRG KCNRG Q8N5I3 Potassium channel regulatory protein chr13 GO:0051051 Not Cancer Driver No 44 0.162 47 7 0.149 0
KEL KEL P23276 Kell blood group glycoprotein chr7 GO:0051051 Compendium Yes 232 0.317 117 39 0.333 0
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0051051 Not Cancer Driver No 46 0.152 72 7 0.097 0
LEP LEP P41159 Leptin chr7 GO:0051051 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0051051 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051051 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0051051 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0051051 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0051051 Not Cancer Driver No 148 0.248 235 50 0.213 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 GO:0051051 Not Cancer Driver No 63 0.124 222 25 0.113 1
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 GO:0051051 Not Cancer Driver No 41 0.115 188 20 0.106 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051051 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0051051 Not Cancer Driver No 172 0.33 57 17 0.298 0
LRRTM2 LRRTM2 O43300 Leucine-rich repeat transmembrane neuronal protein 2 chr5 GO:0051051 Not Cancer Driver No 57 0.11 33 1 0.03 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0051051 Not Cancer Driver No 86 0.119 240 30 0.125 1
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0051051 Not Cancer Driver No 19 0.083 12 2 0.167 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0051051 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0051051 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MCTP1 MCTP1 Q6DN14 Multiple C2 and transmembrane domain-containing protein 1 chr5 GO:0051051 Not Cancer Driver No 162 0.162 323 29 0.09 0
MDFIC_ENST00000393486 MDFIC Q9P1T7 MyoD family inhibitor domain-containing protein chr7 GO:0051051 Not Cancer Driver No 35 0.142 143 23 0.161 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0051051 Not Cancer Driver No 43 0.092 446 43 0.096 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0051051 Not Cancer Driver No 129 0.182 124 26 0.21 0
MRLN_ENST00000414264 MRLN P0DMT0 Myoregulin chr10 GO:0051051 Not Cancer Driver No 1 0.022 0 0 0.0 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0051051 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0051051 Not Cancer Driver No 104 0.287 8 1 0.125 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0051051 Census, Compendium Yes 80 0.182 299 46 0.154 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0051051 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0051051 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0051051 Not Cancer Driver No 27 0.08 198 13 0.066 0
NDUFAF2 NDUFAF2 Q8N183 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 chr5 GO:0051051 Not Cancer Driver No 21 0.124 116 13 0.112 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:0051051 Not Cancer Driver No 46 0.119 122 9 0.074 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0051051 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0051051 Not Cancer Driver No 126 0.129 463 60 0.13 4
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0051051 Not Cancer Driver No 27 0.114 178 18 0.101 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0051051 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0051051 Not Cancer Driver No 104 0.107 344 38 0.11 0
NMB_ENST00000360476 NMB P08949 Neuromedin-B chr15 GO:0051051 Not Cancer Driver No 6 0.05 30 2 0.067 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0051051 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0051051 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0051051 Census, Compendium Yes 363 0.142 686 87 0.127 3
NPSR1_ENST00000360581 NPSR1 Q6W5P4 Neuropeptide S receptor chr7 GO:0051051 Not Cancer Driver No 111 0.299 9 7 0.778 0
NPVF NPVF Q9HCQ7 Pro-FMRFamide-related neuropeptide VF chr7 GO:0051051 Not Cancer Driver No 33 0.168 106 17 0.16 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0051051 Not Cancer Driver No 144 0.324 44 16 0.364 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0051051 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0051051 Not Cancer Driver No 56 0.125 146 13 0.089 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0051051 Census, Compendium Yes 159 0.248 528 132 0.25 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0051051 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUP153_ENST00000262077 NUP153 P49790 Nuclear pore complex protein Nup153 chr6 GO:0051051 Not Cancer Driver No 180 0.122 1152 147 0.128 0
OAZ1 OAZ1 P54368 Ornithine decarboxylase antizyme 1 chr19 GO:0051051 Not Cancer Driver No 30 0.132 109 12 0.11 0
OAZ2 OAZ2 O95190 Ornithine decarboxylase antizyme 2 chr15 GO:0051051 Not Cancer Driver No 15 0.079 11 0 0.0 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 GO:0051051 Not Cancer Driver No 37 0.157 33 2 0.061 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0051051 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0051051 Not Cancer Driver No 81 0.219 0 0 0.0 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0051051 Not Cancer Driver No 107 0.268 58 27 0.466 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0051051 Not Cancer Driver No 72 0.108 451 49 0.109 0
OSM OSM P13725 Oncostatin-M chr22 GO:0051051 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0051051 Not Cancer Driver No 57 0.214 67 17 0.254 0
OSTN OSTN P61366 Osteocrin chr3 GO:0051051 Not Cancer Driver No 30 0.226 54 13 0.241 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0051051 Not Cancer Driver No 69 0.131 208 29 0.139 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0051051 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0051051 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0051051 Not Cancer Driver No 60 0.161 16 1 0.062 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0051051 Not Cancer Driver No 56 0.126 318 47 0.148 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0051051 Not Cancer Driver No 51 0.105 301 27 0.09 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0051051 Not Cancer Driver No 52 0.123 290 31 0.107 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051051 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0051051 Not Cancer Driver No 86 0.124 148 27 0.182 9
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0051051 Not Cancer Driver No 12 0.092 35 5 0.143 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0051051 Not Cancer Driver No 91 0.117 29 4 0.138 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0051051 Census Yes 89 0.137 320 42 0.131 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0051051 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0051051 Not Cancer Driver No 24 0.074 9 0 0.0 0
PIP4P2 PIP4P2 Q8N4L2 Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr8 GO:0051051 Not Cancer Driver No 41 0.16 46 4 0.087 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0051051 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0051051 Not Cancer Driver No 36 0.073 124 0 0.0 0
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0051051 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0051051 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0051051 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0051051 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLN PLN P26678 Cardiac phospholamban chr6 GO:0051051 Not Cancer Driver No 10 0.192 0 0 0.0 3
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0051051 Not Cancer Driver No 43 0.135 92 13 0.141 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 GO:0051051 Not Cancer Driver No 52 0.135 160 25 0.156 2
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0051051 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0051051 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0051051 Compendium Yes 85 0.163 140 27 0.193 7
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0051051 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0051051 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0051051 Census Yes 201 0.22 189 33 0.175 2
PRKG2 PRKG2 Q13237 cGMP-dependent protein kinase 2 chr4 GO:0051051 Not Cancer Driver No 138 0.181 217 48 0.221 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0051051 Not Cancer Driver No 110 0.237 78 15 0.192 31
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0051051 Not Cancer Driver No 111 0.133 34 4 0.118 0
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0051051 Not Cancer Driver No 45 0.132 268 32 0.119 7
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0051051 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0051051 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0051051 Not Cancer Driver No 22 0.099 173 16 0.092 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0051051 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 GO:0051051 Not Cancer Driver No 79 0.203 17 2 0.118 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0051051 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0051051 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0051051 Census, Compendium Yes 129 0.218 260 38 0.146 60
PXK PXK Q7Z7A4 PX domain-containing protein kinase-like protein chr3 GO:0051051 Not Cancer Driver No 71 0.123 169 18 0.107 0
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 GO:0051051 Not Cancer Driver No 145 0.113 1118 133 0.119 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 GO:0051051 Not Cancer Driver No 51 0.067 605 33 0.055 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0051051 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0051051 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAB33B RAB33B Q9H082 Ras-related protein Rab-33B chr4 GO:0051051 Not Cancer Driver No 22 0.096 30 3 0.1 2
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0051051 Not Cancer Driver No 27 0.13 11 0 0.0 4
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0051051 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0051051 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0051051 Not Cancer Driver No 34 0.107 13 0 0.0 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0051051 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0051051 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0051051 Not Cancer Driver No 26 0.141 14 3 0.214 0
REM1 REM1 O75628 GTP-binding protein REM 1 chr20 GO:0051051 Not Cancer Driver No 75 0.252 133 38 0.286 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0051051 Not Cancer Driver No 142 0.129 868 113 0.13 4
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0051051 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0051051 Not Cancer Driver No 68 0.332 5 4 0.8 0
RHBDF1 RHBDF1 Q96CC6 Inactive rhomboid protein 1 chr16 GO:0051051 Not Cancer Driver No 96 0.112 316 44 0.139 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 GO:0051051 Not Cancer Driver No 93 0.109 284 36 0.127 2
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0051051 Not Cancer Driver No 137 0.139 417 61 0.146 0
RRAD RRAD P55042 GTP-binding protein RAD chr16 GO:0051051 Not Cancer Driver No 46 0.149 142 14 0.099 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0051051 Not Cancer Driver No 68 0.188 22 1 0.045 0
RSC1A1 RSC1A1 Q92681 Regulatory solute carrier protein family 1 member 1 chr1 GO:0051051 Not Cancer Driver No 63 0.102 548 54 0.099 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0051051 Not Cancer Driver No 147 0.151 403 57 0.141 0
SCAMP5_ENST00000425597 SCAMP5 Q8TAC9 Secretory carrier-associated membrane protein 5 chr15 GO:0051051 Not Cancer Driver No 41 0.174 2 1 0.5 0
SCT SCT P09683 Secretin chr11 GO:0051051 Not Cancer Driver No 4 0.033 71 3 0.042 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0051051 Not Cancer Driver No 39 0.131 17 2 0.118 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0051051 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0051051 Not Cancer Driver No 101 0.219 442 98 0.222 0
SERGEF SERGEF Q9UGK8 Secretion-regulating guanine nucleotide exchange factor chr11 GO:0051051 Not Cancer Driver No 49 0.107 91 7 0.077 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0051051 Not Cancer Driver No 62 0.156 0 0 0.0 0
SESTD1 SESTD1 Q86VW0 SEC14 domain and spectrin repeat-containing protein 1 chr2 GO:0051051 Not Cancer Driver No 100 0.144 126 18 0.143 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0051051 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0051051 Census Yes 81 0.234 68 22 0.324 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 GO:0051051 Not Cancer Driver No 88 0.254 83 23 0.277 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0051051 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIAH3 SIAH3 Q8IW03 Seven in absentia homolog 3 chr13 GO:0051051 Not Cancer Driver No 60 0.223 51 9 0.176 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0051051 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0051051 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0051051 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0051051 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC30A1 SLC30A1 Q9Y6M5 Zinc transporter 1 chr1 GO:0051051 Not Cancer Driver No 49 0.097 144 9 0.062 0
SLC43A1_ENST00000528450 SLC43A1 O75387 Large neutral amino acids transporter small subunit 3 chr11 GO:0051051 Not Cancer Driver No 64 0.114 55 10 0.182 0
SLC43A2_ENST00000301335 SLC43A2 Q8N370 Large neutral amino acids transporter small subunit 4 chr17 GO:0051051 Not Cancer Driver No 51 0.09 31 8 0.258 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0051051 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0051051 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLN_ENST00000525934 SLN O00631 Sarcolipin chr11 GO:0051051 Not Cancer Driver No 8 0.258 0 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0051051 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX12 SNX12 Q9UMY4 Sorting nexin-12 chrX GO:0051051 Not Cancer Driver No 22 0.136 28 4 0.143 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 GO:0051051 Not Cancer Driver No 21 0.13 37 4 0.108 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0051051 Not Cancer Driver No 63 0.11 204 18 0.088 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0051051 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0051051 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0051051 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPX SPX Q9BT56 Spexin chr12 GO:0051051 Not Cancer Driver No 22 0.19 40 8 0.2 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0051051 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0051051 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRI SRI P30626 Sorcin chr7 GO:0051051 Not Cancer Driver No 15 0.076 32 2 0.062 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0051051 Not Cancer Driver No 59 0.239 58 12 0.207 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0051051 Not Cancer Driver No 64 0.117 182 19 0.104 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0051051 Not Cancer Driver No 38 0.132 155 20 0.129 2
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0051051 Not Cancer Driver No 59 0.1 64 9 0.141 0
STXBP6_ENST00000419632 STXBP6 Q8NFX7 Syntaxin-binding protein 6 chr14 GO:0051051 Not Cancer Driver No 33 0.157 51 6 0.118 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0051051 Census Yes 55 0.114 199 19 0.095 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0051051 Not Cancer Driver No 10 0.099 76 7 0.092 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0051051 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0051051 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0051051 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYTL4 SYTL4 Q96C24 Synaptotagmin-like protein 4 chrX GO:0051051 Not Cancer Driver No 116 0.173 267 34 0.127 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0051051 Not Cancer Driver No 61 0.153 11 4 0.364 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0051051 Not Cancer Driver No 173 0.133 590 90 0.153 0
TCAF2_ENST00000441159 TCAF2 A6NFQ2 TRPM8 channel-associated factor 2 chr7 GO:0051051 Not Cancer Driver No 61 0.066 38 12 0.316 0
TFF2 TFF2 Q03403 Trefoil factor 2 chr21 GO:0051051 Not Cancer Driver No 16 0.124 0 0 0.0 0
THADA_ENST00000405975 THADA Q6YHU6 Thyroid adenoma-associated protein chr2 GO:0051051 Not Cancer Driver No 204 0.104 63 6 0.095 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0051051 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 GO:0051051 Not Cancer Driver No 32 0.199 26 7 0.269 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0051051 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0051051 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0051051 Not Cancer Driver No 16 0.068 3 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051051 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0051051 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0051051 Not Cancer Driver No 48 0.104 229 28 0.122 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0051051 Census Yes 311 0.132 1990 266 0.134 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0051051 Not Cancer Driver No 86 0.462 129 67 0.519 0
TRDN TRDN Q13061 Triadin chr6 GO:0051051 Not Cancer Driver No 129 0.177 639 102 0.16 1
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0051051 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0051051 Census Yes 59 0.115 87 11 0.126 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0051051 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXN TXN P10599 Thioredoxin chr9 GO:0051051 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBAC2 UBAC2 Q8NBM4 Ubiquitin-associated domain-containing protein 2 chr13 GO:0051051 Not Cancer Driver No 33 0.096 57 9 0.158 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0051051 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 GO:0051051 Not Cancer Driver No 33 0.104 158 20 0.127 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0051051 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0051051 Not Cancer Driver No 82 0.131 581 79 0.136 8
UCN UCN P55089 Urocortin chr2 GO:0051051 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0051051 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0051051 Not Cancer Driver No 10 0.118 0 0 0.0 1
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0051051 Not Cancer Driver No 20 0.083 89 4 0.045 1
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0051051 Not Cancer Driver No 105 0.198 201 54 0.269 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0051051 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0051051 Not Cancer Driver No 9 0.09 27 0 0.0 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0051051 Not Cancer Driver No 38 0.134 36 4 0.111 0
VIP VIP P01282 VIP peptides chr6 GO:0051051 Not Cancer Driver No 58 0.341 77 25 0.325 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0051051 Not Cancer Driver No 68 0.085 99 9 0.091 1
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0051051 Not Cancer Driver No 52 0.117 195 22 0.113 0
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 GO:0051051 Not Cancer Driver No 28 0.147 15 3 0.2 0
WDR54 WDR54 Q9H977 WD repeat-containing protein 54 chr2 GO:0051051 Not Cancer Driver No 39 0.117 5 0 0.0 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0051051 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0051051 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0051051 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNK4 WNK4 Q96J92 Serine/threonine-protein kinase WNK4 chr17 GO:0051051 Compendium Yes 178 0.143 916 126 0.138 4
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0051051 Not Cancer Driver No 112 0.129 422 57 0.135 0
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 GO:0051051 Not Cancer Driver No 30 0.086 120 6 0.05 0
YRDC YRDC Q86U90 Threonylcarbamoyl-AMP synthase chr1 GO:0051051 Not Cancer Driver No 17 0.061 45 1 0.022 2
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0051051 Census Yes 32 0.125 41 3 0.073 0