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Total number of protein in "GO:0050921" GO term:  128

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0050921 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0050921 Not Cancer Driver No 80 0.097 182 17 0.093 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0050921 Not Cancer Driver No 31 0.077 297 21 0.071 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0050921 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0050921 Not Cancer Driver No 11 0.057 125 9 0.072 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0050921 Not Cancer Driver No 134 0.147 80 11 0.138 0
ARTN_ENST00000372354 ARTN Q5T4W7 Artemin chr1 GO:0050921 Not Cancer Driver No 11 0.05 154 6 0.039 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0050921 Not Cancer Driver No 42 0.167 53 13 0.245 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0050921 Compendium Yes 141 0.136 601 70 0.116 19
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0050921 Not Cancer Driver No 14 0.05 103 6 0.058 2
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0050921 Not Cancer Driver No 88 0.183 72 16 0.222 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0050921 Not Cancer Driver No 71 0.203 0 0 0.0 0
CALR CALR P27797 Calreticulin chr19 GO:0050921 Census Yes 45 0.108 245 31 0.127 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0050921 Not Cancer Driver No 90 0.234 42 14 0.333 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0050921 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0050921 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0050921 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0050921 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0050921 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0050921 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0050921 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0050921 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0050921 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR4 CCR4 P51679 C-C chemokine receptor type 4 chr3 GO:0050921 Census Yes 45 0.125 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0050921 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0050921 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0050921 Census Yes 31 0.105 185 20 0.108 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0050921 Not Cancer Driver No 168 0.236 235 59 0.251 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0050921 Not Cancer Driver No 107 0.287 24 13 0.542 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0050921 Not Cancer Driver No 33 0.089 168 11 0.065 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0050921 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0050921 Not Cancer Driver No 69 0.125 339 46 0.136 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0050921 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0050921 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0050921 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0050921 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0050921 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0050921 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0050921 Census, Compendium Yes 62 0.176 5 1 0.2 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0050921 Not Cancer Driver No 55 0.149 53 9 0.17 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0050921 Not Cancer Driver No 9 0.127 3 0 0.0 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0050921 Not Cancer Driver No 67 0.091 212 23 0.108 7
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0050921 Not Cancer Driver No 652 0.324 603 201 0.333 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0050921 Not Cancer Driver No 37 0.175 97 20 0.206 3
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0050921 Not Cancer Driver No 55 0.139 7 2 0.286 0
F3 F3 P13726 Tissue factor chr1 GO:0050921 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0050921 Not Cancer Driver No 74 0.159 50 7 0.14 108
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0050921 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF16 FGF16 O43320 Fibroblast growth factor 16 chrX GO:0050921 Not Cancer Driver No 29 0.14 28 6 0.214 1
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0050921 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0050921 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0050921 Census, Compendium Yes 152 0.185 230 43 0.187 74
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0050921 Not Cancer Driver No 96 0.274 26 5 0.192 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0050921 Not Cancer Driver No 82 0.121 42 6 0.143 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0050921 Not Cancer Driver No 25 0.116 203 20 0.099 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0050921 Not Cancer Driver No 10 0.049 118 8 0.068 20
IL16 IL16 Q14005 Pro-interleukin-16 chr15 GO:0050921 Not Cancer Driver No 216 0.162 959 151 0.157 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0050921 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0050921 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0050921 Not Cancer Driver No 18 0.118 0 0 0.0 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0050921 Not Cancer Driver No 166 0.141 26 0 0.0 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0050921 Census, Compendium Yes 357 0.263 275 55 0.2 2
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0050921 Not Cancer Driver No 84 0.175 6 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0050921 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0050921 Not Cancer Driver No 57 0.132 112 19 0.17 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0050921 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0050921 Not Cancer Driver No 38 0.1 49 5 0.102 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0050921 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0050921 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0050921 Not Cancer Driver No 363 0.128 476 59 0.124 3
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0050921 Census, Compendium Yes 226 0.163 62 15 0.242 19
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX GO:0050921 Not Cancer Driver No 58 0.112 143 16 0.112 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0050921 Not Cancer Driver No 68 0.181 64 11 0.172 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0050921 Not Cancer Driver No 247 0.219 51 10 0.196 4
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0050921 Compendium Yes 146 0.158 211 31 0.147 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0050921 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0050921 Census, Compendium Yes 249 0.297 57 21 0.368 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0050921 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0050921 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0050921 Not Cancer Driver No 57 0.167 21 2 0.095 3
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0050921 Census Yes 37 0.154 99 22 0.222 2
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0050921 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0050921 Census, Compendium Yes 164 0.148 231 44 0.19 7
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0050921 Not Cancer Driver No 30 0.136 72 10 0.139 0
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0050921 Not Cancer Driver No 70 0.159 27 7 0.259 2
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0050921 Not Cancer Driver No 53 0.117 242 24 0.099 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0050921 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0050921 Compendium Yes 118 0.134 246 34 0.138 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0050921 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0050921 Not Cancer Driver No 134 0.127 425 55 0.129 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0050921 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0050921 Not Cancer Driver No 31 0.161 0 0 0.0 2
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0050921 Not Cancer Driver No 16 0.098 14 2 0.143 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0050921 Not Cancer Driver No 131 0.123 421 76 0.181 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0050921 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0050921 Census Yes 39 0.386 28 14 0.5 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0050921 Not Cancer Driver No 86 0.225 29 6 0.207 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0050921 Not Cancer Driver No 116 0.188 531 103 0.194 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0050921 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0050921 Not Cancer Driver No 78 0.194 7 2 0.286 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0050921 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0050921 Not Cancer Driver No 428 0.28 31 13 0.419 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0050921 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0050921 Not Cancer Driver No 82 0.184 216 52 0.241 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0050921 Not Cancer Driver No 46 0.17 187 34 0.182 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0050921 Not Cancer Driver No 64 0.117 182 19 0.104 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0050921 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0050921 Not Cancer Driver No 50 0.168 152 20 0.132 0
SUCNR1 SUCNR1 Q9BXA5 Succinate receptor 1 chr3 GO:0050921 Not Cancer Driver No 51 0.153 0 0 0.0 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0050921 Not Cancer Driver No 44 0.075 271 18 0.066 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0050921 Not Cancer Driver No 41 0.105 41 4 0.098 10
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0050921 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0050921 Not Cancer Driver No 137 0.143 281 40 0.142 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0050921 Not Cancer Driver No 28 0.127 80 6 0.075 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0050921 Not Cancer Driver No 38 0.075 141 13 0.092 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0050921 Census Yes 7 0.159 44 7 0.159 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0050921 Not Cancer Driver No 58 0.242 18 1 0.056 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0050921 Not Cancer Driver No 58 0.138 13 1 0.077 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0050921 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0050921 Not Cancer Driver No 142 0.163 231 34 0.147 44
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0050921 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0050921 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0050921 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0050921 Not Cancer Driver No 59 0.167 33 6 0.182 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0050921 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0050921 Not Cancer Driver No 66 0.174 0 0 0.0 2
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0050921 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0050921 Not Cancer Driver No 20 0.175 35 5 0.143 0