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Total number of protein in "GO:0050770" GO term:  128

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0050770 Not Cancer Driver No 130 0.118 615 66 0.107 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0050770 Not Cancer Driver No 104 0.127 146 26 0.178 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0050770 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0050770 Not Cancer Driver No 125 0.132 464 76 0.164 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0050770 Not Cancer Driver No 47 0.19 79 19 0.241 1
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0050770 Compendium Yes 141 0.136 601 70 0.116 19
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0050770 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0050770 Not Cancer Driver No 90 0.122 321 39 0.121 0
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0050770 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0050770 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0050770 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0050770 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0050770 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0050770 Not Cancer Driver No 165 0.172 685 120 0.175 18
CHN1 CHN1 P15882 N-chimaerin chr2 GO:0050770 Not Cancer Driver No 69 0.15 44 9 0.205 7
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0050770 Not Cancer Driver No 155 0.149 370 61 0.165 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0050770 Not Cancer Driver No 27 0.196 23 6 0.261 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0050770 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0050770 Not Cancer Driver No 46 0.037 96 0 0.0 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0050770 Not Cancer Driver No 200 0.34 393 143 0.364 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0050770 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0050770 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0050770 Census, Compendium Yes 530 0.366 631 215 0.341 2
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0050770 Not Cancer Driver No 181 0.115 375 49 0.131 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0050770 Not Cancer Driver No 132 0.155 514 82 0.16 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0050770 Not Cancer Driver No 61 0.175 249 48 0.193 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0050770 Not Cancer Driver No 652 0.324 603 201 0.333 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0050770 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0050770 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0050770 Not Cancer Driver No 45 0.132 183 22 0.12 0
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0050770 Not Cancer Driver No 104 0.115 382 43 0.113 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0050770 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0050770 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0050770 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0050770 Not Cancer Driver No 155 0.155 137 16 0.117 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0050770 Not Cancer Driver No 70 0.286 96 33 0.344 2
FN1 FN1 P02751 Fibronectin chr2 GO:0050770 Compendium Yes 394 0.159 1243 185 0.149 8
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0050770 Not Cancer Driver No 134 0.159 96 12 0.125 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0050770 Not Cancer Driver No 69 0.154 34 6 0.176 2
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0050770 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0050770 Not Cancer Driver No 56 0.133 146 13 0.089 0
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0050770 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0050770 Not Cancer Driver No 31 0.085 185 17 0.092 0
KEL KEL P23276 Kell blood group glycoprotein chr7 GO:0050770 Compendium Yes 232 0.317 117 39 0.333 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0050770 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF13B KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 GO:0050770 Not Cancer Driver No 187 0.102 968 82 0.085 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0050770 Not Cancer Driver No 228 0.181 442 75 0.17 54
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0050770 Not Cancer Driver No 110 0.17 170 30 0.176 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0050770 Not Cancer Driver No 65 0.184 9 0 0.0 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0050770 Not Cancer Driver No 233 0.122 265 28 0.106 11
LRRC4C LRRC4C Q9HCJ2 Leucine-rich repeat-containing protein 4C chr11 GO:0050770 Not Cancer Driver No 271 0.423 152 54 0.355 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0050770 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0050770 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0050770 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0050770 Compendium Yes 367 0.201 1726 340 0.197 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0050770 Census Yes 157 0.163 593 91 0.153 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0050770 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0050770 Compendium Yes 124 0.157 445 70 0.157 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0050770 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0050770 Not Cancer Driver No 218 0.236 124 33 0.266 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0050770 Not Cancer Driver No 363 0.128 476 59 0.124 3
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0050770 Not Cancer Driver No 7 0.103 0 0 0.0 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0050770 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0050770 Not Cancer Driver No 92 0.169 285 39 0.137 12
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0050770 Not Cancer Driver No 66 0.274 93 25 0.269 1
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0050770 Compendium Yes 146 0.158 211 31 0.147 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0050770 Not Cancer Driver No 57 0.094 66 4 0.061 2
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0050770 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0050770 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0050770 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0050770 Not Cancer Driver No 127 0.227 286 64 0.224 2
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0050770 Not Cancer Driver No 243 0.13 199 34 0.171 0
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0050770 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0050770 Not Cancer Driver No 130 0.318 308 87 0.282 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0050770 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0050770 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0050770 Not Cancer Driver No 250 0.128 829 111 0.134 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0050770 Not Cancer Driver No 31 0.144 43 4 0.093 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0050770 Census, Compendium Yes 208 0.187 105 12 0.114 139
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0050770 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0050770 Compendium Yes 91 0.133 601 87 0.145 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0050770 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0050770 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0050770 Not Cancer Driver No 75 0.16 204 29 0.142 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0050770 Not Cancer Driver No 55 0.091 85 4 0.047 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0050770 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0050770 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0050770 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0050770 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0050770 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0050770 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0050770 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0050770 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0050770 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0050770 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0050770 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0050770 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0050770 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0050770 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0050770 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0050770 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0050770 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0050770 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0050770 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0050770 Not Cancer Driver No 81 0.122 150 21 0.14 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0050770 Census Yes 68 0.108 470 52 0.111 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0050770 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0050770 Not Cancer Driver No 221 0.144 36 1 0.028 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 GO:0050770 Not Cancer Driver No 112 0.168 396 68 0.172 1
SPP1 SPP1 P10451 Osteopontin chr4 GO:0050770 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRF SRF P11831 Serum response factor chr6 GO:0050770 Not Cancer Driver No 44 0.087 443 42 0.095 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0050770 Not Cancer Driver No 153 0.114 830 90 0.108 2
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0050770 Not Cancer Driver No 24 0.149 5 0 0.0 0
TNR TNR Q92752 Tenascin-R chr1 GO:0050770 Not Cancer Driver No 496 0.365 358 128 0.358 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0050770 Not Cancer Driver No 115 0.152 173 30 0.173 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0050770 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0050770 Not Cancer Driver No 105 0.137 175 23 0.131 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0050770 Not Cancer Driver No 34 0.097 59 8 0.136 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0050770 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0050770 Not Cancer Driver No 132 0.127 519 84 0.162 0
UST UST Q9Y2C2 Uronyl 2-sulfotransferase chr6 GO:0050770 Not Cancer Driver No 70 0.172 57 8 0.14 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0050770 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0050770 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0050770 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0050770 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0050770 Not Cancer Driver No 93 0.266 18 9 0.5 4
XK XK P51811 Endoplasmic reticulum membrane adapter protein XK chrX GO:0050770 Not Cancer Driver No 86 0.194 32 6 0.188 3
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0050770 Not Cancer Driver No 45 0.109 140 22 0.157 1