Total number of protein in "GO:0050661" GO term: 52
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ASPDH | ASPDH | A6ND91 | Aspartate dehydrogenase domain-containing protein | chr19 | GO:0050661 | Not Cancer Driver | No | 27 | 0.095 | 81 | 5 | 0.062 | 0 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0050661 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CBR3 | CBR3 | O75828 | Carbonyl reductase [NADPH] 3 | chr21 | GO:0050661 | Not Cancer Driver | No | 26 | 0.094 | 66 | 6 | 0.091 | 0 |
| CBR4 | CBR4 | Q8N4T8 | 3-oxoacyl-[acyl-carrier-protein] reductase | chr4 | GO:0050661 | Not Cancer Driver | No | 15 | 0.063 | 4 | 0 | 0.0 | 0 |
| CRYM | CRYM | Q14894 | Ketimine reductase mu-crystallin | chr16 | GO:0050661 | Not Cancer Driver | No | 34 | 0.108 | 10 | 0 | 0.0 | 1 |
| CRYZL1 | CRYZL1 | O95825 | Quinone oxidoreductase-like protein 1 | chr21 | GO:0050661 | Not Cancer Driver | No | 30 | 0.086 | 1 | 0 | 0.0 | 0 |
| CRYZ_ENST00000340866 | CRYZ | Q08257 | Quinone oxidoreductase | chr1 | GO:0050661 | Not Cancer Driver | No | 49 | 0.149 | 0 | 0 | 0.0 | 0 |
| DECR1 | DECR1 | Q16698 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial | chr8 | GO:0050661 | Not Cancer Driver | No | 38 | 0.113 | 11 | 0 | 0.0 | 0 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | GO:0050661 | Not Cancer Driver | No | 85 | 0.179 | 7 | 1 | 0.143 | 53 |
| DHFR | DHFR | P00374 | Dihydrofolate reductase | chr5 | GO:0050661 | Not Cancer Driver | No | 16 | 0.086 | 12 | 2 | 0.167 | 2 |
| DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | GO:0050661 | Not Cancer Driver | No | 25 | 0.134 | 20 | 0 | 0.0 | 0 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0050661 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| DUOX1 | DUOX1 | Q9NRD9 | Dual oxidase 1 | chr15 | GO:0050661 | Not Cancer Driver | No | 193 | 0.124 | 158 | 17 | 0.108 | 0 |
| DUS2 | DUS2 | Q9NX74 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | chr16 | GO:0050661 | Not Cancer Driver | No | 48 | 0.097 | 117 | 10 | 0.085 | 0 |
| FMO1 | FMO1 | Q01740 | Dimethylaniline monooxygenase [N-oxide-forming] 1 | chr1 | GO:0050661 | Not Cancer Driver | No | 133 | 0.25 | 3 | 0 | 0.0 | 0 |
| FMO2 | FMO2 | Q99518 | Flavin-containing monooxygenase 2 | chr1 | GO:0050661 | Not Cancer Driver | No | 125 | 0.234 | 3 | 0 | 0.0 | 0 |
| FMO3 | FMO3 | P31513 | Dimethylaniline monooxygenase [N-oxide-forming] 3 | chr1 | GO:0050661 | Not Cancer Driver | No | 146 | 0.274 | 15 | 9 | 0.6 | 8 |
| FMO4 | FMO4 | P31512 | Dimethylaniline monooxygenase [N-oxide-forming] 4 | chr1 | GO:0050661 | Not Cancer Driver | No | 110 | 0.197 | 8 | 5 | 0.625 | 0 |
| FMO5 | FMO5 | P49326 | Flavin-containing monooxygenase 5 | chr1 | GO:0050661 | Not Cancer Driver | No | 82 | 0.154 | 32 | 4 | 0.125 | 0 |
| G6PD_ENST00000621232 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0050661 | Not Cancer Driver | No | 86 | 0.167 | 28 | 3 | 0.107 | 58 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0050661 | Not Cancer Driver | No | 39 | 0.116 | 24 | 3 | 0.125 | 0 |
| GAPDHS | GAPDHS | O14556 | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | chr19 | GO:0050661 | Not Cancer Driver | No | 71 | 0.174 | 111 | 19 | 0.171 | 0 |
| GLYR1 | GLYR1 | Q49A26 | Putative oxidoreductase GLYR1 | chr16 | GO:0050661 | Not Cancer Driver | No | 87 | 0.157 | 201 | 27 | 0.134 | 0 |
| GMDS | GMDS | O60547 | GDP-mannose 4,6 dehydratase | chr6 | GO:0050661 | Not Cancer Driver | No | 51 | 0.137 | 53 | 6 | 0.113 | 0 |
| GRHPR | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | GO:0050661 | Not Cancer Driver | No | 31 | 0.095 | 36 | 4 | 0.111 | 0 |
| GSR | GSR | P00390 | Glutathione reductase, mitochondrial | chr8 | GO:0050661 | Not Cancer Driver | No | 53 | 0.102 | 55 | 5 | 0.091 | 1 |
| H6PD_ENST00000377403 | H6PD | O95479 | GDH/6PGL endoplasmic bifunctional protein | chr1 | GO:0050661 | Not Cancer Driver | No | 96 | 0.121 | 39 | 3 | 0.077 | 2 |
| HIBADH | HIBADH | P31937 | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | chr7 | GO:0050661 | Not Cancer Driver | No | 28 | 0.083 | 7 | 2 | 0.286 | 0 |
| HMGCR_ENST00000511206 | HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | chr5 | GO:0050661 | Not Cancer Driver | No | 84 | 0.095 | 112 | 12 | 0.107 | 0 |
| HSD11B1_ENST00000367027 | HSD11B1 | P28845 | 11-beta-hydroxysteroid dehydrogenase 1 | chr1 | GO:0050661 | Not Cancer Driver | No | 57 | 0.195 | 0 | 0 | 0.0 | 0 |
| HSD17B1_ENST00000585807 | HSD17B1 | P14061 | 17-beta-hydroxysteroid dehydrogenase type 1 | chr17 | GO:0050661 | Not Cancer Driver | No | 48 | 0.146 | 59 | 28 | 0.475 | 0 |
| IDH1 | IDH1 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | chr2 | GO:0050661 | Census, Compendium | Yes | 553 | 1.336 | 37 | 3 | 0.081 | 0 |
| KCNAB1 | KCNAB1 | Q14722 | Voltage-gated potassium channel subunit beta-1 | chr3 | GO:0050661 | Not Cancer Driver | No | 89 | 0.212 | 83 | 23 | 0.277 | 0 |
| LBR_ENST00000272163 | LBR | Q14739 | Delta(14)-sterol reductase LBR | chr1 | GO:0050661 | Not Cancer Driver | No | 95 | 0.154 | 130 | 15 | 0.115 | 5 |
| ME1 | ME1 | P48163 | NADP-dependent malic enzyme | chr6 | GO:0050661 | Not Cancer Driver | No | 109 | 0.191 | 64 | 10 | 0.156 | 0 |
| ME3_ENST00000393324 | ME3 | Q16798 | NADP-dependent malic enzyme, mitochondrial | chr11 | GO:0050661 | Not Cancer Driver | No | 105 | 0.174 | 45 | 9 | 0.2 | 0 |
| MTHFR_ENST00000376590 | MTHFR | P42898 | Methylenetetrahydrofolate reductase | chr1 | GO:0050661 | Not Cancer Driver | No | 95 | 0.145 | 125 | 22 | 0.176 | 53 |
| MTRR_ENST00000440940 | MTRR | Q9UBK8 | Methionine synthase reductase | chr5 | GO:0050661 | Not Cancer Driver | No | 101 | 0.145 | 84 | 13 | 0.155 | 5 |
| NDOR1_ENST00000344894 | NDOR1 | Q9UHB4 | NADPH-dependent diflavin oxidoreductase 1 | chr9 | GO:0050661 | Not Cancer Driver | No | 60 | 0.101 | 67 | 7 | 0.104 | 0 |
| NNT_ENST00000344920 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial | chr5 | GO:0050661 | Not Cancer Driver | No | 129 | 0.119 | 47 | 6 | 0.128 | 11 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0050661 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0050661 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0050661 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NOX1 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0050661 | Not Cancer Driver | No | 101 | 0.179 | 18 | 8 | 0.444 | 0 |
| NOX5 | NOX5 | Q96PH1 | NADPH oxidase 5 | chr15 | GO:0050661 | Not Cancer Driver | No | 118 | 0.154 | 95 | 9 | 0.095 | 0 |
| PGD | PGD | P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | chr1 | GO:0050661 | Not Cancer Driver | No | 73 | 0.151 | 19 | 3 | 0.158 | 0 |
| POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | GO:0050661 | Not Cancer Driver | No | 62 | 0.092 | 93 | 4 | 0.043 | 9 |
| QDPR | QDPR | P09417 | Dihydropteridine reductase | chr4 | GO:0050661 | Not Cancer Driver | No | 41 | 0.168 | 25 | 3 | 0.12 | 16 |
| SPR | SPR | P35270 | Sepiapterin reductase | chr2 | GO:0050661 | Not Cancer Driver | No | 23 | 0.088 | 19 | 4 | 0.211 | 2 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0050661 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| TM7SF2 | TM7SF2 | O76062 | Delta(14)-sterol reductase TM7SF2 | chr11 | GO:0050661 | Not Cancer Driver | No | 51 | 0.122 | 15 | 1 | 0.067 | 0 |
| TP53I3 | TP53I3 | Q53FA7 | Quinone oxidoreductase PIG3 | chr2 | GO:0050661 | Not Cancer Driver | No | 30 | 0.09 | 40 | 7 | 0.175 | 0 |