Total number of protein in "GO:0050660" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AC090527.2 | AC090527.2 | H3BNX3 | Pyr_redox_2 domain-containing protein (Fragment) | chr15 | GO:0050660 | Not Cancer Driver | No | 36 | 0.125 | 22 | 4 | 0.182 | 0 |
| ACAD10_ENST00000313698 | ACAD10 | Q6JQN1 | Acyl-CoA dehydrogenase family member 10 | chr12 | GO:0050660 | Not Cancer Driver | No | 143 | 0.135 | 91 | 19 | 0.209 | 0 |
| ACAD11 | ACAD11 | Q709F0 | Acyl-CoA dehydrogenase family member 11 | chr3 | GO:0050660 | Not Cancer Driver | No | 108 | 0.138 | 33 | 4 | 0.121 | 0 |
| ACAD8 | ACAD8 | Q9UKU7 | Isobutyryl-CoA dehydrogenase, mitochondrial | chr11 | GO:0050660 | Not Cancer Driver | No | 55 | 0.133 | 13 | 1 | 0.077 | 9 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | GO:0050660 | Not Cancer Driver | No | 69 | 0.111 | 28 | 5 | 0.179 | 12 |
| ACADL | ACADL | P28330 | Long-chain specific acyl-CoA dehydrogenase, mitochondrial | chr2 | GO:0050660 | Not Cancer Driver | No | 63 | 0.147 | 51 | 3 | 0.059 | 0 |
| ACADM_ENST00000370841 | ACADM | P11310 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | chr1 | GO:0050660 | Not Cancer Driver | No | 61 | 0.145 | 41 | 5 | 0.122 | 19 |
| ACADS | ACADS | P16219 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | chr12 | GO:0050660 | Not Cancer Driver | No | 53 | 0.129 | 16 | 3 | 0.188 | 10 |
| ACADSB | ACADSB | P45954 | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | chr10 | GO:0050660 | Not Cancer Driver | No | 59 | 0.137 | 16 | 3 | 0.188 | 1 |
| ACADVL_ENST00000356839 | ACADVL | P49748 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | chr17 | GO:0050660 | Not Cancer Driver | No | 50 | 0.076 | 100 | 5 | 0.05 | 37 |
| ACOX1_ENST00000301608 | ACOX1 | Q15067 | Peroxisomal acyl-coenzyme A oxidase 1 | chr17 | GO:0050660 | Not Cancer Driver | No | 71 | 0.108 | 63 | 11 | 0.175 | 7 |
| ACOX2 | ACOX2 | Q99424 | Peroxisomal acyl-coenzyme A oxidase 2 | chr3 | GO:0050660 | Not Cancer Driver | No | 79 | 0.116 | 35 | 9 | 0.257 | 1 |
| ACOX3 | ACOX3 | O15254 | Peroxisomal acyl-coenzyme A oxidase 3 | chr4 | GO:0050660 | Not Cancer Driver | No | 107 | 0.153 | 26 | 6 | 0.231 | 0 |
| ACOXL_ENST00000389811 | ACOXL | Q9NUZ1 | Acyl-coenzyme A oxidase-like protein | chr2 | GO:0050660 | Not Cancer Driver | No | 96 | 0.176 | 21 | 4 | 0.19 | 0 |
| AGPS | AGPS | O00116 | Alkyldihydroxyacetonephosphate synthase, peroxisomal | chr2 | GO:0050660 | Not Cancer Driver | No | 68 | 0.103 | 151 | 10 | 0.066 | 6 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0050660 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| AIFM2_ENST00000307864 | AIFM2 | Q9BRQ8 | Ferroptosis suppressor protein 1 | chr10 | GO:0050660 | Not Cancer Driver | No | 47 | 0.126 | 8 | 0 | 0.0 | 0 |
| AIFM3 | AIFM3 | Q96NN9 | Apoptosis-inducing factor 3 | chr22 | GO:0050660 | Not Cancer Driver | No | 87 | 0.144 | 66 | 15 | 0.227 | 0 |
| AOX1 | AOX1 | Q06278 | Aldehyde oxidase | chr2 | GO:0050660 | Not Cancer Driver | No | 238 | 0.178 | 70 | 11 | 0.157 | 0 |
| CHDH | CHDH | Q8NE62 | Choline dehydrogenase, mitochondrial | chr3 | GO:0050660 | Not Cancer Driver | No | 59 | 0.099 | 116 | 7 | 0.06 | 0 |
| COQ6 | COQ6 | Q9Y2Z9 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial | chr14 | GO:0050660 | Not Cancer Driver | No | 58 | 0.124 | 20 | 2 | 0.1 | 2 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0050660 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0050660 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| CYB5R1 | CYB5R1 | Q9UHQ9 | NADH-cytochrome b5 reductase 1 | chr1 | GO:0050660 | Not Cancer Driver | No | 43 | 0.141 | 22 | 1 | 0.045 | 0 |
| CYB5R2_ENST00000299498 | CYB5R2 | Q6BCY4 | NADH-cytochrome b5 reductase 2 | chr11 | GO:0050660 | Not Cancer Driver | No | 34 | 0.123 | 78 | 10 | 0.128 | 0 |
| CYB5R3_ENST00000352397 | CYB5R3 | P00387 | NADH-cytochrome b5 reductase 3 | chr22 | GO:0050660 | Not Cancer Driver | No | 42 | 0.14 | 24 | 3 | 0.125 | 9 |
| CYBB | CYBB | P04839 | Cytochrome b-245 heavy chain | chrX | GO:0050660 | Not Cancer Driver | No | 109 | 0.191 | 11 | 3 | 0.273 | 65 |
| D2HGDH | D2HGDH | Q8N465 | D-2-hydroxyglutarate dehydrogenase, mitochondrial | chr2 | GO:0050660 | Not Cancer Driver | No | 61 | 0.117 | 46 | 1 | 0.022 | 0 |
| DAO | DAO | P14920 | D-amino-acid oxidase | chr12 | GO:0050660 | Not Cancer Driver | No | 103 | 0.297 | 28 | 13 | 0.464 | 0 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0050660 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | GO:0050660 | Not Cancer Driver | No | 67 | 0.132 | 17 | 0 | 0.0 | 10 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0050660 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| DUS1L_ENST00000306796 | DUS1L | Q6P1R4 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like | chr17 | GO:0050660 | Not Cancer Driver | No | 52 | 0.11 | 110 | 10 | 0.091 | 0 |
| DUS2 | DUS2 | Q9NX74 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | chr16 | GO:0050660 | Not Cancer Driver | No | 48 | 0.097 | 117 | 10 | 0.085 | 0 |
| DUS3L | DUS3L | Q96G46 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like | chr19 | GO:0050660 | Not Cancer Driver | No | 82 | 0.126 | 234 | 27 | 0.115 | 0 |
| DUS4L | DUS4L | O95620 | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like | chr7 | GO:0050660 | Not Cancer Driver | No | 38 | 0.12 | 3 | 0 | 0.0 | 0 |
| ERO1A | ERO1A | Q96HE7 | ERO1-like protein alpha | chr14 | GO:0050660 | Not Cancer Driver | No | 48 | 0.103 | 32 | 5 | 0.156 | 0 |
| ERO1B | ERO1B | Q86YB8 | ERO1-like protein beta | chr1 | GO:0050660 | Not Cancer Driver | No | 59 | 0.126 | 20 | 2 | 0.1 | 0 |
| ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | GO:0050660 | Not Cancer Driver | No | 30 | 0.09 | 34 | 2 | 0.059 | 3 |
| ETFDH | ETFDH | Q16134 | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | chr4 | GO:0050660 | Not Cancer Driver | No | 61 | 0.099 | 64 | 4 | 0.062 | 12 |
| FMO1 | FMO1 | Q01740 | Dimethylaniline monooxygenase [N-oxide-forming] 1 | chr1 | GO:0050660 | Not Cancer Driver | No | 133 | 0.25 | 3 | 0 | 0.0 | 0 |
| FMO2 | FMO2 | Q99518 | Flavin-containing monooxygenase 2 | chr1 | GO:0050660 | Not Cancer Driver | No | 125 | 0.234 | 3 | 0 | 0.0 | 0 |
| FMO3 | FMO3 | P31513 | Dimethylaniline monooxygenase [N-oxide-forming] 3 | chr1 | GO:0050660 | Not Cancer Driver | No | 146 | 0.274 | 15 | 9 | 0.6 | 8 |
| FMO4 | FMO4 | P31512 | Dimethylaniline monooxygenase [N-oxide-forming] 4 | chr1 | GO:0050660 | Not Cancer Driver | No | 110 | 0.197 | 8 | 5 | 0.625 | 0 |
| FMO5 | FMO5 | P49326 | Flavin-containing monooxygenase 5 | chr1 | GO:0050660 | Not Cancer Driver | No | 82 | 0.154 | 32 | 4 | 0.125 | 0 |
| FOXRED2 | FOXRED2 | Q8IWF2 | FAD-dependent oxidoreductase domain-containing protein 2 | chr22 | GO:0050660 | Not Cancer Driver | No | 97 | 0.142 | 48 | 5 | 0.104 | 0 |
| GCDH_ENST00000591470 | GCDH | Q92947 | Glutaryl-CoA dehydrogenase, mitochondrial | chr19 | GO:0050660 | Not Cancer Driver | No | 57 | 0.13 | 37 | 5 | 0.135 | 58 |
| GFER | GFER | P55789 | FAD-linked sulfhydryl oxidase ALR | chr16 | GO:0050660 | Not Cancer Driver | No | 10 | 0.049 | 97 | 4 | 0.041 | 1 |
| GSR | GSR | P00390 | Glutathione reductase, mitochondrial | chr8 | GO:0050660 | Not Cancer Driver | No | 53 | 0.102 | 55 | 5 | 0.091 | 1 |
| ILVBL | ILVBL | A1L0T0 | 2-hydroxyacyl-CoA lyase 2 | chr19 | GO:0050660 | Not Cancer Driver | No | 86 | 0.136 | 30 | 1 | 0.033 | 0 |
| IVD | IVD | P26440 | Isovaleryl-CoA dehydrogenase, mitochondrial | chr15 | GO:0050660 | Not Cancer Driver | No | 46 | 0.108 | 8 | 0 | 0.0 | 14 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0050660 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| KDM1B_ENST00000449850 | KDM1B | Q8NB78 | Lysine-specific histone demethylase 1B | chr6 | GO:0050660 | Not Cancer Driver | No | 81 | 0.099 | 74 | 11 | 0.149 | 0 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0050660 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| LDHD | LDHD | Q86WU2 | Probable D-lactate dehydrogenase, mitochondrial | chr16 | GO:0050660 | Not Cancer Driver | No | 55 | 0.108 | 48 | 6 | 0.125 | 2 |
| MAOA | MAOA | P21397 | Amine oxidase [flavin-containing] A | chrX | GO:0050660 | Not Cancer Driver | No | 61 | 0.116 | 23 | 4 | 0.174 | 0 |
| MAOB | MAOB | P27338 | Amine oxidase [flavin-containing] B | chrX | GO:0050660 | Not Cancer Driver | No | 75 | 0.144 | 44 | 6 | 0.136 | 0 |
| MICAL1_ENST00000358807 | MICAL1 | Q8TDZ2 | [F-actin]-monooxygenase MICAL1 | chr6 | GO:0050660 | Not Cancer Driver | No | 112 | 0.105 | 364 | 37 | 0.102 | 0 |
| MICAL2_ENST00000646065 | MICAL2 | O94851 | [F-actin]-monooxygenase MICAL2 | chr11 | GO:0050660 | Not Cancer Driver | No | 297 | 0.152 | 1191 | 179 | 0.15 | 0 |
| MICAL3 | MICAL3 | Q7RTP6 | [F-actin]-monooxygenase MICAL3 | chr22 | GO:0050660 | Not Cancer Driver | No | 248 | 0.124 | 1264 | 159 | 0.126 | 0 |
| MMACHC | MMACHC | Q9Y4U1 | Cyanocobalamin reductase / alkylcobalamin dealkylase | chr1 | GO:0050660 | Not Cancer Driver | No | 29 | 0.103 | 85 | 5 | 0.059 | 14 |
| MTHFR_ENST00000376590 | MTHFR | P42898 | Methylenetetrahydrofolate reductase | chr1 | GO:0050660 | Not Cancer Driver | No | 95 | 0.145 | 125 | 22 | 0.176 | 53 |
| MTO1_ENST00000370300 | MTO1 | Q9Y2Z2 | Protein MTO1 homolog, mitochondrial | chr6 | GO:0050660 | Not Cancer Driver | No | 70 | 0.098 | 61 | 2 | 0.033 | 1 |
| MTRR_ENST00000440940 | MTRR | Q9UBK8 | Methionine synthase reductase | chr5 | GO:0050660 | Not Cancer Driver | No | 101 | 0.145 | 84 | 13 | 0.155 | 5 |
| NDOR1_ENST00000344894 | NDOR1 | Q9UHB4 | NADPH-dependent diflavin oxidoreductase 1 | chr9 | GO:0050660 | Not Cancer Driver | No | 60 | 0.101 | 67 | 7 | 0.104 | 0 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0050660 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0050660 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0050660 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:0050660 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| NOX5 | NOX5 | Q96PH1 | NADPH oxidase 5 | chr15 | GO:0050660 | Not Cancer Driver | No | 118 | 0.154 | 95 | 9 | 0.095 | 0 |
| NQO2_ENST00000380430 | NQO2 | P16083 | Ribosyldihydronicotinamide dehydrogenase [quinone] | chr6 | GO:0050660 | Not Cancer Driver | No | 28 | 0.121 | 10 | 1 | 0.1 | 0 |
| POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | GO:0050660 | Not Cancer Driver | No | 62 | 0.092 | 93 | 4 | 0.043 | 9 |
| PPOX | PPOX | P50336 | Protoporphyrinogen oxidase | chr1 | GO:0050660 | Not Cancer Driver | No | 48 | 0.101 | 34 | 6 | 0.176 | 56 |
| PRODH2 | PRODH2 | Q9UF12 | Hydroxyproline dehydrogenase | chr19 | GO:0050660 | Not Cancer Driver | No | 96 | 0.179 | 51 | 7 | 0.137 | 0 |
| PRODH_ENST00000610940 | PRODH | O43272 | Proline dehydrogenase 1, mitochondrial | chr22 | GO:0050660 | Not Cancer Driver | No | 62 | 0.103 | 67 | 8 | 0.119 | 16 |
| PYROXD1 | PYROXD1 | Q8WU10 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | chr12 | GO:0050660 | Not Cancer Driver | No | 54 | 0.108 | 34 | 2 | 0.059 | 2 |
| QSOX1 | QSOX1 | O00391 | Sulfhydryl oxidase 1 | chr1 | GO:0050660 | Not Cancer Driver | No | 93 | 0.124 | 189 | 22 | 0.116 | 0 |
| SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | GO:0050660 | Census | Yes | 115 | 0.173 | 71 | 13 | 0.183 | 7 |
| SQLE | SQLE | Q14534 | Squalene monooxygenase | chr8 | GO:0050660 | Not Cancer Driver | No | 54 | 0.094 | 40 | 5 | 0.125 | 0 |
| SQOR_ENST00000568606 | SQOR | Q9Y6N5 | Sulfide:quinone oxidoreductase, mitochondrial | chr15 | GO:0050660 | Not Cancer Driver | No | 54 | 0.12 | 41 | 8 | 0.195 | 1 |
| STEAP4 | STEAP4 | Q687X5 | Metalloreductase STEAP4 | chr7 | GO:0050660 | Not Cancer Driver | No | 97 | 0.211 | 0 | 0 | 0.0 | 0 |
| TXNRD1 | TXNRD1 | Q16881 | Thioredoxin reductase 1, cytoplasmic | chr12 | GO:0050660 | Not Cancer Driver | No | 85 | 0.131 | 67 | 9 | 0.134 | 0 |
| TXNRD2 | TXNRD2 | Q9NNW7 | Thioredoxin reductase 2, mitochondrial | chr22 | GO:0050660 | Not Cancer Driver | No | 70 | 0.134 | 46 | 6 | 0.13 | 0 |
| TXNRD3_ENST00000640433 | TXNRD3 | Q86VQ6 | Thioredoxin reductase 3 | chr3 | GO:0050660 | Not Cancer Driver | No | 2 | 0.003 | 66 | 0 | 0.0 | 0 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0050660 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |