Total number of protein in "GO:0048771" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0048771 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0048771 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0048771 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0048771 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AGTR2 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:0048771 | Not Cancer Driver | No | 98 | 0.27 | 0 | 0 | 0.0 | 0 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0048771 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | GO:0048771 | Not Cancer Driver | No | 40 | 0.145 | 25 | 6 | 0.24 | 1 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0048771 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0048771 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0048771 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0048771 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0048771 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| BSX | BSX | Q3C1V8 | Brain-specific homeobox protein homolog | chr11 | GO:0048771 | Not Cancer Driver | No | 46 | 0.197 | 184 | 42 | 0.228 | 0 |
| CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | GO:0048771 | Not Cancer Driver | No | 68 | 0.095 | 32 | 2 | 0.062 | 1 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0048771 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0048771 | Not Cancer Driver | No | 81 | 0.217 | 23 | 1 | 0.043 | 0 |
| CELA1 | CELA1 | Q9UNI1 | Chymotrypsin-like elastase family member 1 | chr12 | GO:0048771 | Not Cancer Driver | No | 48 | 0.186 | 20 | 0 | 0.0 | 0 |
| CHD7 | CHD7 | Q9P2D1 | Chromodomain-helicase-DNA-binding protein 7 | chr8 | GO:0048771 | Not Cancer Driver | No | 464 | 0.155 | 1872 | 299 | 0.16 | 50 |
| CRB1 | CRB1 | P82279 | Protein crumbs homolog 1 | chr1 | GO:0048771 | Not Cancer Driver | No | 464 | 0.33 | 28 | 5 | 0.179 | 74 |
| CSPG4 | CSPG4 | Q6UVK1 | Chondroitin sulfate proteoglycan 4 | chr15 | GO:0048771 | Not Cancer Driver | No | 259 | 0.112 | 838 | 85 | 0.101 | 0 |
| DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0048771 | Not Cancer Driver | No | 125 | 0.203 | 71 | 17 | 0.239 | 3 |
| DLL4 | DLL4 | Q9NR61 | Delta-like protein 4 | chr15 | GO:0048771 | Not Cancer Driver | No | 75 | 0.109 | 73 | 15 | 0.205 | 7 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0048771 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| ELF3_ENST00000367283 | ELF3 | P78545 | ETS-related transcription factor Elf-3 | chr1 | GO:0048771 | Census, Compendium | Yes | 94 | 0.253 | 145 | 34 | 0.234 | 0 |
| EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | GO:0048771 | Census, Compendium | Yes | 120 | 0.138 | 449 | 53 | 0.118 | 6 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0048771 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0048771 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0048771 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF8_ENST00000344255 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0048771 | Not Cancer Driver | No | 30 | 0.129 | 79 | 9 | 0.114 | 6 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0048771 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FOXC1_ENST00000645831 | FOXC1 | Q12948 | Forkhead box protein C1 | chr6 | GO:0048771 | Not Cancer Driver | No | 33 | 0.06 | 411 | 24 | 0.058 | 32 |
| FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0048771 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0048771 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0048771 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HOXA3_ENST00000396352 | HOXA3 | O43365 | Homeobox protein Hox-A3 | chr7 | GO:0048771 | Not Cancer Driver | No | 86 | 0.194 | 417 | 84 | 0.201 | 0 |
| IGFBP5 | IGFBP5 | P24593 | Insulin-like growth factor-binding protein 5 | chr2 | GO:0048771 | Not Cancer Driver | No | 27 | 0.099 | 112 | 17 | 0.152 | 0 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0048771 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0048771 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| JAG1 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0048771 | Not Cancer Driver | No | 182 | 0.149 | 172 | 20 | 0.116 | 52 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0048771 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| LIPA | LIPA | P38571 | Lysosomal acid lipase/cholesteryl ester hydrolase | chr10 | GO:0048771 | Not Cancer Driver | No | 44 | 0.11 | 12 | 1 | 0.083 | 4 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0048771 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0048771 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
| MMP14 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0048771 | Not Cancer Driver | No | 64 | 0.11 | 118 | 11 | 0.093 | 1 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0048771 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0048771 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0048771 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| PLG | PLG | P00747 | Plasminogen | chr6 | GO:0048771 | Not Cancer Driver | No | 242 | 0.299 | 230 | 64 | 0.278 | 9 |
| RBPJ_ENST00000361572 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | GO:0048771 | Not Cancer Driver | No | 49 | 0.098 | 151 | 19 | 0.126 | 2 |
| RSPO3 | RSPO3 | Q9BXY4 | R-spondin-3 | chr6 | GO:0048771 | Census | Yes | 44 | 0.162 | 100 | 12 | 0.12 | 0 |
| SEMA3C | SEMA3C | Q99985 | Semaphorin-3C | chr7 | GO:0048771 | Not Cancer Driver | No | 136 | 0.181 | 111 | 23 | 0.207 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0048771 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| THBS4 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0048771 | Not Cancer Driver | No | 137 | 0.143 | 281 | 40 | 0.142 | 0 |
| TIE1 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0048771 | Not Cancer Driver | No | 200 | 0.176 | 223 | 46 | 0.206 | 0 |
| TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0048771 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |