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Total number of protein in "GO:0048514" GO term:  90

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0048514 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0048514 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0048514 Not Cancer Driver No 255 0.189 53 11 0.208 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0048514 Not Cancer Driver No 52 0.113 154 26 0.169 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0048514 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOE APOE P02649 Apolipoprotein E chr19 GO:0048514 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0048514 Census, Compendium Yes 272 0.148 1143 141 0.123 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0048514 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0048514 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0048514 Compendium Yes 141 0.136 601 70 0.116 19
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0048514 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCM2_ENST00000258781 CCM2 Q9BSQ5 Cerebral cavernous malformations 2 protein chr7 GO:0048514 Not Cancer Driver No 58 0.131 132 8 0.061 3
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0048514 Not Cancer Driver No 238 0.263 461 130 0.282 7
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0048514 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0048514 Not Cancer Driver No 23 0.085 230 18 0.078 0
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0048514 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0048514 Not Cancer Driver No 97 0.128 306 52 0.17 61
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0048514 Not Cancer Driver No 61 0.112 31 3 0.097 40
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0048514 Not Cancer Driver No 75 0.109 73 15 0.205 7
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0048514 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0048514 Not Cancer Driver No 62 0.145 21 6 0.286 2
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0048514 Not Cancer Driver No 42 0.126 97 15 0.155 0
ENG ENG P17813 Endoglin chr9 GO:0048514 Not Cancer Driver No 60 0.091 114 15 0.132 32
ETV2_ENST00000403402 ETV2 O00321 ETS translocation variant 2 chr19 GO:0048514 Not Cancer Driver No 23 0.067 227 15 0.066 0
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0048514 Not Cancer Driver No 168 0.284 341 99 0.29 15
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0048514 Not Cancer Driver No 30 0.129 79 9 0.114 6
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 GO:0048514 Not Cancer Driver No 60 0.103 134 8 0.06 3
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0048514 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0048514 Census, Compendium Yes 253 0.186 259 41 0.158 13
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0048514 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0048514 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0048514 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0048514 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0048514 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0048514 Not Cancer Driver No 90 0.139 483 65 0.135 2
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0048514 Not Cancer Driver No 57 0.106 33 5 0.152 19
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0048514 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0048514 Not Cancer Driver No 74 0.207 92 21 0.228 5
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0048514 Not Cancer Driver No 47 0.217 124 29 0.234 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0048514 Not Cancer Driver No 173 0.125 974 135 0.139 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0048514 Not Cancer Driver No 37 0.132 226 32 0.142 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0048514 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0048514 Not Cancer Driver No 64 0.19 179 26 0.145 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0048514 Census Yes 37 0.095 171 22 0.129 4
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0048514 Not Cancer Driver No 90 0.269 262 68 0.26 0
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0048514 Not Cancer Driver No 32 0.12 4 1 0.25 2
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0048514 Not Cancer Driver No 20 0.129 17 6 0.353 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0048514 Not Cancer Driver No 182 0.149 172 20 0.116 52
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 GO:0048514 Not Cancer Driver No 600 0.195 329 71 0.216 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0048514 Not Cancer Driver No 119 0.138 63 3 0.048 104
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0048514 Compendium Yes 44 0.106 172 11 0.064 4
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0048514 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0048514 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0048514 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP5L_ENST00000402785 LRP5L A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein chr22 GO:0048514 Not Cancer Driver No 38 0.151 39 5 0.128 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0048514 Not Cancer Driver No 284 0.303 853 263 0.308 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0048514 Census, Compendium Yes 375 0.132 406 47 0.116 85
NOG NOG Q13253 Noggin chr17 GO:0048514 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0048514 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0048514 Not Cancer Driver No 306 0.132 557 81 0.145 110
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:0048514 Not Cancer Driver No 45 0.079 158 22 0.139 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0048514 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0048514 Compendium Yes 146 0.158 211 31 0.147 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0048514 Census, Compendium Yes 164 0.148 231 44 0.19 7
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0048514 Not Cancer Driver No 113 0.117 375 35 0.093 10
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0048514 Census, Compendium Yes 145 0.176 337 66 0.196 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0048514 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0048514 Census, Compendium Yes 69 0.282 205 49 0.239 1
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0048514 Compendium Yes 154 0.147 181 25 0.138 3
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0048514 Not Cancer Driver No 49 0.098 151 19 0.126 2
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 GO:0048514 Not Cancer Driver No 135 0.106 526 55 0.105 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0048514 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0048514 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SGCD_ENST00000435422 SGCD Q92629 Delta-sarcoglycan chr5 GO:0048514 Not Cancer Driver No 67 0.232 74 20 0.27 2
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0048514 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0048514 Not Cancer Driver No 69 0.132 17 4 0.235 1
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0048514 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0048514 Compendium Yes 197 0.148 458 62 0.135 38
SRF SRF P11831 Serum response factor chr6 GO:0048514 Not Cancer Driver No 44 0.087 443 42 0.095 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0048514 Not Cancer Driver No 77 0.115 84 14 0.167 6
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0048514 Census Yes 96 0.151 131 27 0.206 5
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0048514 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0048514 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0048514 Not Cancer Driver No 117 0.262 201 54 0.269 2
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0048514 Not Cancer Driver No 114 0.248 306 75 0.245 6
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0048514 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0048514 Not Cancer Driver No 86 0.171 23 3 0.13 15
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0048514 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0048514 Not Cancer Driver No 55 0.155 59 4 0.068 0
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0048514 Not Cancer Driver No 148 0.139 762 111 0.146 5