Total number of protein in "GO:0046928" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY1 | ADCY1 | Q08828 | Adenylate cyclase type 1 | chr7 | GO:0046928 | Not Cancer Driver | No | 244 | 0.218 | 99 | 19 | 0.192 | 0 |
| ADORA2A | ADORA2A | P29274 | Adenosine receptor A2a | chr22 | GO:0046928 | Not Cancer Driver | No | 61 | 0.148 | 93 | 11 | 0.118 | 0 |
| ADORA2B | ADORA2B | P29275 | Adenosine receptor A2b | chr17 | GO:0046928 | Not Cancer Driver | No | 23 | 0.069 | 0 | 0 | 0.0 | 0 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0046928 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0046928 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| APBA1 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | GO:0046928 | Not Cancer Driver | No | 149 | 0.178 | 556 | 103 | 0.185 | 0 |
| ASIC1_ENST00000447966 | ASIC1 | P78348 | Acid-sensing ion channel 1 | chr12 | GO:0046928 | Not Cancer Driver | No | 69 | 0.131 | 17 | 2 | 0.118 | 0 |
| ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | GO:0046928 | Not Cancer Driver | No | 136 | 0.131 | 78 | 14 | 0.179 | 41 |
| BACE1 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0046928 | Not Cancer Driver | No | 55 | 0.11 | 53 | 5 | 0.094 | 0 |
| BAIAP3 | BAIAP3 | O94812 | BAI1-associated protein 3 | chr16 | GO:0046928 | Not Cancer Driver | No | 170 | 0.143 | 230 | 35 | 0.152 | 0 |
| CACNB2 | CACNB2 | Q08289 | Voltage-dependent L-type calcium channel subunit beta-2 | chr10 | GO:0046928 | Not Cancer Driver | No | 155 | 0.235 | 478 | 106 | 0.222 | 0 |
| CALM3_ENST00000596362 | CALM3 | P0DP25 | Calmodulin-3 | chr19 | GO:0046928 | Not Cancer Driver | No | 17 | 0.114 | 115 | 10 | 0.087 | 3 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0046928 | Not Cancer Driver | No | 83 | 0.174 | 62 | 10 | 0.161 | 7 |
| CASK_ENST00000378163 | CASK | O14936 | Peripheral plasma membrane protein CASK | chrX | GO:0046928 | Not Cancer Driver | No | 118 | 0.127 | 285 | 45 | 0.158 | 4 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0046928 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CHRNA3 | CHRNA3 | P32297 | Neuronal acetylcholine receptor subunit alpha-3 | chr15 | GO:0046928 | Not Cancer Driver | No | 86 | 0.17 | 11 | 1 | 0.091 | 0 |
| CHRNA5 | CHRNA5 | P30532 | Neuronal acetylcholine receptor subunit alpha-5 | chr15 | GO:0046928 | Not Cancer Driver | No | 63 | 0.135 | 24 | 3 | 0.125 | 0 |
| CHRNA6 | CHRNA6 | Q15825 | Neuronal acetylcholine receptor subunit alpha-6 | chr8 | GO:0046928 | Not Cancer Driver | No | 101 | 0.204 | 33 | 6 | 0.182 | 0 |
| CHRNB3 | CHRNB3 | Q05901 | Neuronal acetylcholine receptor subunit beta-3 | chr8 | GO:0046928 | Not Cancer Driver | No | 125 | 0.273 | 4 | 1 | 0.25 | 0 |
| CHRNB4 | CHRNB4 | P30926 | Neuronal acetylcholine receptor subunit beta-4 | chr15 | GO:0046928 | Not Cancer Driver | No | 98 | 0.197 | 30 | 6 | 0.2 | 0 |
| CNR1_ENST00000549890 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0046928 | Not Cancer Driver | No | 129 | 0.273 | 9 | 1 | 0.111 | 0 |
| CPLX1 | CPLX1 | O14810 | Complexin-1 | chr4 | GO:0046928 | Not Cancer Driver | No | 19 | 0.142 | 134 | 19 | 0.142 | 0 |
| CPLX2_ENST00000515094 | CPLX2 | Q6PUV4 | Complexin-2 | chr5 | GO:0046928 | Not Cancer Driver | No | 27 | 0.201 | 134 | 27 | 0.201 | 0 |
| CPLX3 | CPLX3 | Q8WVH0 | Complexin-3 | chr15 | GO:0046928 | Not Cancer Driver | No | 26 | 0.165 | 149 | 25 | 0.168 | 0 |
| CPLX4 | CPLX4 | Q7Z7G2 | Complexin-4 | chr18 | GO:0046928 | Not Cancer Driver | No | 36 | 0.225 | 142 | 33 | 0.232 | 0 |
| CSPG5 | CSPG5 | O95196 | Chondroitin sulfate proteoglycan 5 | chr3 | GO:0046928 | Not Cancer Driver | No | 75 | 0.133 | 397 | 46 | 0.116 | 0 |
| DRD1 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0046928 | Not Cancer Driver | No | 73 | 0.164 | 30 | 4 | 0.133 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0046928 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DTNBP1 | DTNBP1 | Q96EV8 | Dysbindin | chr6 | GO:0046928 | Not Cancer Driver | No | 49 | 0.14 | 210 | 25 | 0.119 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0046928 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| FBXL20 | FBXL20 | Q96IG2 | F-box/LRR-repeat protein 20 | chr17 | GO:0046928 | Not Cancer Driver | No | 48 | 0.11 | 1 | 0 | 0.0 | 0 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | GO:0046928 | Not Cancer Driver | No | 124 | 0.196 | 327 | 70 | 0.214 | 3 |
| GIPC1 | GIPC1 | O14908 | PDZ domain-containing protein GIPC1 | chr19 | GO:0046928 | Not Cancer Driver | No | 47 | 0.141 | 138 | 17 | 0.123 | 0 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0046928 | Not Cancer Driver | No | 67 | 0.088 | 434 | 42 | 0.097 | 0 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0046928 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GRIN3A | GRIN3A | Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | chr9 | GO:0046928 | Not Cancer Driver | No | 308 | 0.276 | 179 | 22 | 0.123 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0046928 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HCRT | HCRT | O43612 | Orexin | chr17 | GO:0046928 | Not Cancer Driver | No | 3 | 0.023 | 45 | 0 | 0.0 | 1 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0046928 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0046928 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| KCNMB4 | KCNMB4 | Q86W47 | Calcium-activated potassium channel subunit beta-4 | chr12 | GO:0046928 | Not Cancer Driver | No | 41 | 0.195 | 0 | 0 | 0.0 | 0 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0046928 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0046928 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MCTP1 | MCTP1 | Q6DN14 | Multiple C2 and transmembrane domain-containing protein 1 | chr5 | GO:0046928 | Not Cancer Driver | No | 162 | 0.162 | 323 | 29 | 0.09 | 0 |
| MCTP2 | MCTP2 | Q6DN12 | Multiple C2 and transmembrane domain-containing protein 2 | chr15 | GO:0046928 | Not Cancer Driver | No | 188 | 0.214 | 202 | 42 | 0.208 | 0 |
| MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0046928 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0046928 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| NLGN1_ENST00000361589 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0046928 | Not Cancer Driver | No | 214 | 0.248 | 248 | 61 | 0.246 | 4 |
| P2RX1 | P2RX1 | P51575 | P2X purinoceptor 1 | chr17 | GO:0046928 | Not Cancer Driver | No | 59 | 0.148 | 14 | 1 | 0.071 | 0 |
| P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | GO:0046928 | Not Cancer Driver | No | 60 | 0.161 | 16 | 1 | 0.062 | 0 |
| P2RY4 | P2RY4 | P51582 | P2Y purinoceptor 4 | chrX | GO:0046928 | Not Cancer Driver | No | 66 | 0.181 | 10 | 2 | 0.2 | 0 |
| PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | GO:0046928 | Not Cancer Driver | No | 20 | 0.143 | 0 | 0 | 0.0 | 0 |
| PNKD | PNKD | Q8N490 | Probable hydrolase PNKD | chr2 | GO:0046928 | Not Cancer Driver | No | 52 | 0.135 | 160 | 25 | 0.156 | 2 |
| PREPL_ENST00000409272 | PREPL | Q4J6C6 | Prolyl endopeptidase-like | chr2 | GO:0046928 | Not Cancer Driver | No | 107 | 0.147 | 91 | 20 | 0.22 | 0 |
| PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | GO:0046928 | Census, Compendium | Yes | 205 | 0.306 | 148 | 40 | 0.27 | 0 |
| PRKCG | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:0046928 | Not Cancer Driver | No | 172 | 0.247 | 151 | 43 | 0.285 | 5 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0046928 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| RAB3A | RAB3A | P20336 | Ras-related protein Rab-3A | chr19 | GO:0046928 | Not Cancer Driver | No | 25 | 0.114 | 43 | 4 | 0.093 | 0 |
| RAB3GAP1_ENST00000264158 | RAB3GAP1 | Q15042 | Rab3 GTPase-activating protein catalytic subunit | chr2 | GO:0046928 | Not Cancer Driver | No | 123 | 0.125 | 294 | 32 | 0.109 | 2 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | GO:0046928 | Not Cancer Driver | No | 32 | 0.149 | 65 | 15 | 0.231 | 0 |
| RAP1A_ENST00000356415 | RAP1A | P62834 | Ras-related protein Rap-1A | chr1 | GO:0046928 | Not Cancer Driver | No | 27 | 0.147 | 5 | 0 | 0.0 | 0 |
| RAP1B_ENST00000393436 | RAP1B | P61224 | Ras-related protein Rap-1b | chr12 | GO:0046928 | Not Cancer Driver | No | 26 | 0.141 | 14 | 3 | 0.214 | 0 |
| RIMS1 | RIMS1 | Q86UR5 | Regulating synaptic membrane exocytosis protein 1 | chr6 | GO:0046928 | Not Cancer Driver | No | 403 | 0.238 | 1315 | 306 | 0.233 | 1 |
| RIMS3 | RIMS3 | Q9UJD0 | Regulating synaptic membrane exocytosis protein 3 | chr1 | GO:0046928 | Not Cancer Driver | No | 61 | 0.198 | 162 | 39 | 0.241 | 0 |
| RIMS4_ENST00000372851 | RIMS4 | Q9H426 | Regulating synaptic membrane exocytosis protein 4 | chr20 | GO:0046928 | Not Cancer Driver | No | 63 | 0.234 | 71 | 13 | 0.183 | 0 |
| SEPT5 | SEPTIN5 | Q99719 | Septin-5 | chr22 | GO:0046928 | Not Cancer Driver | No | 50 | 0.136 | 76 | 5 | 0.066 | 0 |
| SLC30A1 | SLC30A1 | Q9Y6M5 | Zinc transporter 1 | chr1 | GO:0046928 | Not Cancer Driver | No | 49 | 0.097 | 144 | 9 | 0.062 | 0 |
| SLC4A8 | SLC4A8 | Q2Y0W8 | Electroneutral sodium bicarbonate exchanger 1 | chr12 | GO:0046928 | Not Cancer Driver | No | 176 | 0.161 | 276 | 41 | 0.149 | 0 |
| SNAPIN | SNAPIN | O95295 | SNARE-associated protein Snapin | chr1 | GO:0046928 | Not Cancer Driver | No | 9 | 0.066 | 62 | 5 | 0.081 | 0 |
| SNCAIP_ENST00000261368 | SNCAIP | Q9Y6H5 | Synphilin-1 | chr5 | GO:0046928 | Not Cancer Driver | No | 221 | 0.24 | 719 | 189 | 0.263 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0046928 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SNCG | SNCG | O76070 | Gamma-synuclein | chr10 | GO:0046928 | Not Cancer Driver | No | 11 | 0.087 | 111 | 10 | 0.09 | 0 |
| STX1A | STX1A | Q16623 | Syntaxin-1A | chr7 | GO:0046928 | Not Cancer Driver | No | 35 | 0.122 | 136 | 11 | 0.081 | 0 |
| STX1B | STX1B | P61266 | Syntaxin-1B | chr16 | GO:0046928 | Not Cancer Driver | No | 38 | 0.132 | 155 | 20 | 0.129 | 2 |
| STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0046928 | Not Cancer Driver | No | 97 | 0.163 | 111 | 23 | 0.207 | 18 |
| STXBP5 | STXBP5 | Q5T5C0 | Syntaxin-binding protein 5 | chr6 | GO:0046928 | Not Cancer Driver | No | 128 | 0.111 | 344 | 46 | 0.134 | 0 |
| SYN1 | SYN1 | P17600 | Synapsin-1 | chrX | GO:0046928 | Not Cancer Driver | No | 75 | 0.106 | 445 | 27 | 0.061 | 0 |
| SYP | SYP | P08247 | Synaptophysin | chrX | GO:0046928 | Not Cancer Driver | No | 36 | 0.115 | 93 | 8 | 0.086 | 1 |
| SYT11 | SYT11 | Q9BT88 | Synaptotagmin-11 | chr1 | GO:0046928 | Not Cancer Driver | No | 64 | 0.148 | 105 | 23 | 0.219 | 0 |
| SYT12_ENST00000527043 | SYT12 | Q8IV01 | Synaptotagmin-12 | chr11 | GO:0046928 | Not Cancer Driver | No | 71 | 0.169 | 73 | 13 | 0.178 | 0 |
| SYT1_ENST00000393240 | SYT1 | P21579 | Synaptotagmin-1 | chr12 | GO:0046928 | Not Cancer Driver | No | 104 | 0.246 | 103 | 36 | 0.35 | 5 |
| SYT4 | SYT4 | Q9H2B2 | Synaptotagmin-4 | chr18 | GO:0046928 | Not Cancer Driver | No | 111 | 0.261 | 107 | 41 | 0.383 | 0 |
| TACR2 | TACR2 | P21452 | Substance-K receptor | chr10 | GO:0046928 | Not Cancer Driver | No | 61 | 0.153 | 11 | 4 | 0.364 | 0 |
| VPS18 | VPS18 | Q9P253 | Vacuolar protein sorting-associated protein 18 homolog | chr15 | GO:0046928 | Not Cancer Driver | No | 96 | 0.099 | 86 | 7 | 0.081 | 0 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0046928 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |