Total number of protein in "GO:0046686" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0046686 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0046686 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ALAD | ALAD | P13716 | Delta-aminolevulinic acid dehydratase | chr9 | GO:0046686 | Not Cancer Driver | No | 52 | 0.158 | 13 | 3 | 0.231 | 5 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0046686 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0046686 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0046686 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0046686 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0046686 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CER1 | CER1 | O95813 | Cerberus | chr9 | GO:0046686 | Not Cancer Driver | No | 70 | 0.262 | 119 | 27 | 0.227 | 0 |
| CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0046686 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
| CYBB | CYBB | P04839 | Cytochrome b-245 heavy chain | chrX | GO:0046686 | Not Cancer Driver | No | 109 | 0.191 | 11 | 3 | 0.273 | 65 |
| CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0046686 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
| DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0046686 | Census, Compendium | Yes | 106 | 0.143 | 549 | 81 | 0.148 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0046686 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0046686 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| FOS | FOS | P01100 | Protein c-Fos | chr14 | GO:0046686 | Not Cancer Driver | No | 45 | 0.118 | 245 | 33 | 0.135 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0046686 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0046686 | Not Cancer Driver | No | 77 | 0.138 | 73 | 11 | 0.151 | 24 |
| GSS_ENST00000216951 | GSS | P48637 | Glutathione synthetase | chr20 | GO:0046686 | Not Cancer Driver | No | 61 | 0.129 | 49 | 6 | 0.122 | 14 |
| HAAO | HAAO | P46952 | 3-hydroxyanthranilate 3,4-dioxygenase | chr2 | GO:0046686 | Not Cancer Driver | No | 40 | 0.14 | 30 | 2 | 0.067 | 0 |
| HESX1 | HESX1 | Q9UBX0 | Homeobox expressed in ES cells 1 | chr3 | GO:0046686 | Not Cancer Driver | No | 32 | 0.173 | 59 | 9 | 0.153 | 6 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0046686 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0046686 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:0046686 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0046686 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0046686 | Census, Compendium | Yes | 62 | 0.172 | 2 | 0 | 0.0 | 7 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0046686 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0046686 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
| MAPK9 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0046686 | Not Cancer Driver | No | 59 | 0.139 | 90 | 8 | 0.089 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0046686 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MT1A | MT1A | P04731 | Metallothionein-1A | chr16 | GO:0046686 | Not Cancer Driver | No | 8 | 0.131 | 0 | 0 | 0.0 | 0 |
| MT1B | MT1B | P07438 | Metallothionein-1B | chr16 | GO:0046686 | Not Cancer Driver | No | 7 | 0.115 | 0 | 0 | 0.0 | 0 |
| MT1E | MT1E | P04732 | Metallothionein-1E | chr16 | GO:0046686 | Not Cancer Driver | No | 4 | 0.066 | 0 | 0 | 0.0 | 0 |
| MT1F | MT1F | P04733 | Metallothionein-1F | chr16 | GO:0046686 | Not Cancer Driver | No | 3 | 0.049 | 0 | 0 | 0.0 | 0 |
| MT1G | MT1G | P13640 | Metallothionein-1G | chr16 | GO:0046686 | Not Cancer Driver | No | 9 | 0.145 | 0 | 0 | 0.0 | 0 |
| MT1H | MT1H | P80294 | Metallothionein-1H | chr16 | GO:0046686 | Not Cancer Driver | No | 18 | 0.295 | 0 | 0 | 0.0 | 0 |
| MT1HL1 | MT1HL1 | P0DM35 | Metallothionein 1H-like protein 1 | chr1 | GO:0046686 | Not Cancer Driver | No | 16 | 0.262 | 0 | 0 | 0.0 | 0 |
| MT1M | MT1M | Q8N339 | Metallothionein-1M | chr16 | GO:0046686 | Not Cancer Driver | No | 11 | 0.18 | 0 | 0 | 0.0 | 0 |
| MT1X | MT1X | P80297 | Metallothionein-1X | chr16 | GO:0046686 | Not Cancer Driver | No | 3 | 0.049 | 0 | 0 | 0.0 | 0 |
| MT2A | MT2A | P02795 | Metallothionein-2 | chr16 | GO:0046686 | Not Cancer Driver | No | 8 | 0.131 | 0 | 0 | 0.0 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0046686 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| MT4 | MT4 | P47944 | Metallothionein-4 | chr16 | GO:0046686 | Not Cancer Driver | No | 11 | 0.177 | 0 | 0 | 0.0 | 0 |
| MTF1 | MTF1 | Q14872 | Metal regulatory transcription factor 1 | chr1 | GO:0046686 | Not Cancer Driver | No | 115 | 0.153 | 553 | 76 | 0.137 | 0 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0046686 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0046686 | Not Cancer Driver | No | 155 | 0.121 | 24 | 0 | 0.0 | 150 |
| NUDT1_ENST00000397046 | NUDT1 | P36639 | Oxidized purine nucleoside triphosphate hydrolase | chr7 | GO:0046686 | Not Cancer Driver | No | 25 | 0.16 | 17 | 4 | 0.235 | 0 |
| OGG1_ENST00000344629 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0046686 | Not Cancer Driver | No | 37 | 0.107 | 71 | 12 | 0.169 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0046686 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0046686 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PTH | PTH | P01270 | Parathyroid hormone | chr11 | GO:0046686 | Not Cancer Driver | No | 19 | 0.165 | 60 | 10 | 0.167 | 2 |
| SLC34A1 | SLC34A1 | Q06495 | Sodium-dependent phosphate transport protein 2A | chr5 | GO:0046686 | Not Cancer Driver | No | 92 | 0.144 | 46 | 8 | 0.174 | 9 |
| SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0046686 | Not Cancer Driver | No | 16 | 0.104 | 93 | 9 | 0.097 | 79 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0046686 | Not Cancer Driver | No | 32 | 0.144 | 25 | 5 | 0.2 | 0 |
| SORD | SORD | Q00796 | Sorbitol dehydrogenase | chr15 | GO:0046686 | Not Cancer Driver | No | 29 | 0.081 | 41 | 7 | 0.171 | 3 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0046686 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0046686 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |