Total number of protein in "GO:0046330" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0046330 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| ANKRD6_ENST00000339746 | ANKRD6 | Q9Y2G4 | Ankyrin repeat domain-containing protein 6 | chr6 | GO:0046330 | Not Cancer Driver | No | 91 | 0.125 | 500 | 61 | 0.122 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0046330 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0046330 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BIRC7 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0046330 | Not Cancer Driver | No | 52 | 0.174 | 136 | 22 | 0.162 | 0 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0046330 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0046330 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0046330 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
| CCN2 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0046330 | Not Cancer Driver | No | 58 | 0.166 | 0 | 0 | 0.0 | 0 |
| CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0046330 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:0046330 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0046330 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CRACR2A | CRACR2A | Q9BSW2 | EF-hand calcium-binding domain-containing protein 4B | chr12 | GO:0046330 | Not Cancer Driver | No | 88 | 0.12 | 436 | 60 | 0.138 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0046330 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DIXDC1 | DIXDC1 | Q155Q3 | Dixin | chr11 | GO:0046330 | Not Cancer Driver | No | 72 | 0.105 | 495 | 55 | 0.111 | 0 |
| DUSP15 | DUSP15 | Q9H1R2 | Dual specificity protein phosphatase 15 | chr20 | GO:0046330 | Not Cancer Driver | No | 36 | 0.122 | 122 | 19 | 0.156 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0046330 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
| DUSP22_ENST00000344450 | DUSP22 | Q9NRW4 | Dual specificity protein phosphatase 22 | chr6 | GO:0046330 | Not Cancer Driver | No | 84 | 0.457 | 0 | 0 | 0.0 | 0 |
| EDA2R_ENST00000451436 | EDA2R | Q9HAV5 | Tumor necrosis factor receptor superfamily member 27 | chrX | GO:0046330 | Not Cancer Driver | No | 52 | 0.175 | 72 | 11 | 0.153 | 0 |
| EDAR | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | GO:0046330 | Not Cancer Driver | No | 81 | 0.181 | 116 | 20 | 0.172 | 18 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0046330 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0046330 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FGF19 | FGF19 | O95750 | Fibroblast growth factor 19 | chr11 | GO:0046330 | Not Cancer Driver | No | 20 | 0.093 | 36 | 7 | 0.194 | 0 |
| FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0046330 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0046330 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0046330 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
| GADD45B | GADD45B | O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta | chr19 | GO:0046330 | Not Cancer Driver | No | 9 | 0.056 | 14 | 0 | 0.0 | 0 |
| GADD45G | GADD45G | O95257 | Growth arrest and DNA damage-inducible protein GADD45 gamma | chr9 | GO:0046330 | Not Cancer Driver | No | 13 | 0.082 | 20 | 2 | 0.1 | 0 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0046330 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0046330 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0046330 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0046330 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0046330 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| LTBR | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | GO:0046330 | Not Cancer Driver | No | 44 | 0.101 | 200 | 21 | 0.105 | 0 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0046330 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP3K10 | MAP3K10 | Q02779 | Mitogen-activated protein kinase kinase kinase 10 | chr19 | GO:0046330 | Not Cancer Driver | No | 112 | 0.117 | 589 | 62 | 0.105 | 0 |
| MAP3K11 | MAP3K11 | Q16584 | Mitogen-activated protein kinase kinase kinase 11 | chr11 | GO:0046330 | Not Cancer Driver | No | 97 | 0.115 | 466 | 54 | 0.116 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0046330 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MAP4K2 | MAP4K2 | Q12851 | Mitogen-activated protein kinase kinase kinase kinase 2 | chr11 | GO:0046330 | Not Cancer Driver | No | 78 | 0.095 | 243 | 23 | 0.095 | 0 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0046330 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MAPK8IP3_ENST00000250894 | MAPK8IP3 | Q9UPT6 | C-Jun-amino-terminal kinase-interacting protein 3 | chr16 | GO:0046330 | Not Cancer Driver | No | 179 | 0.134 | 746 | 110 | 0.147 | 3 |
| MAPKBP1 | MAPKBP1 | O60336 | Mitogen-activated protein kinase-binding protein 1 | chr15 | GO:0046330 | Not Cancer Driver | No | 166 | 0.11 | 786 | 67 | 0.085 | 0 |
| MBIP | MBIP | Q9NS73 | MAP3K12-binding inhibitory protein 1 | chr14 | GO:0046330 | Not Cancer Driver | No | 47 | 0.137 | 190 | 20 | 0.105 | 0 |
| MFHAS1 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0046330 | Not Cancer Driver | No | 95 | 0.09 | 98 | 9 | 0.092 | 0 |
| MINK1 | MINK1 | Q8N4C8 | Misshapen-like kinase 1 | chr17 | GO:0046330 | Not Cancer Driver | No | 113 | 0.085 | 740 | 56 | 0.076 | 0 |
| MMP8 | MMP8 | P22894 | Neutrophil collagenase | chr11 | GO:0046330 | Not Cancer Driver | No | 73 | 0.156 | 115 | 19 | 0.165 | 0 |
| MTURN | MTURN | Q8N3F0 | Maturin | chr7 | GO:0046330 | Not Cancer Driver | No | 15 | 0.115 | 27 | 6 | 0.222 | 0 |
| MYD88_ENST00000396334 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0046330 | Census, Compendium | Yes | 37 | 0.125 | 47 | 1 | 0.021 | 2 |
| NAIP_ENST00000194097 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0046330 | Not Cancer Driver | No | 39 | 0.028 | 67 | 4 | 0.06 | 0 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0046330 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0046330 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0046330 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NOX1 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0046330 | Not Cancer Driver | No | 101 | 0.179 | 18 | 8 | 0.444 | 0 |
| PJA2 | PJA2 | O43164 | E3 ubiquitin-protein ligase Praja-2 | chr5 | GO:0046330 | Not Cancer Driver | No | 80 | 0.113 | 598 | 66 | 0.11 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0046330 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0046330 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0046330 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0046330 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RASSF2 | RASSF2 | P50749 | Ras association domain-containing protein 2 | chr20 | GO:0046330 | Not Cancer Driver | No | 90 | 0.276 | 126 | 44 | 0.349 | 0 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0046330 | Not Cancer Driver | No | 202 | 0.127 | 578 | 75 | 0.13 | 0 |
| RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0046330 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0046330 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| SDCBP_ENST00000260130 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0046330 | Not Cancer Driver | No | 39 | 0.131 | 17 | 2 | 0.118 | 0 |
| SEMA3A | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0046330 | Not Cancer Driver | No | 195 | 0.253 | 164 | 46 | 0.28 | 10 |
| SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0046330 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0046330 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0046330 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SH3RF3 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0046330 | Not Cancer Driver | No | 98 | 0.111 | 564 | 53 | 0.094 | 0 |
| SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0046330 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
| STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0046330 | Not Cancer Driver | No | 70 | 0.143 | 241 | 32 | 0.133 | 0 |
| TAOK1 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0046330 | Not Cancer Driver | No | 116 | 0.116 | 601 | 59 | 0.098 | 0 |
| TAOK2 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0046330 | Not Cancer Driver | No | 191 | 0.155 | 666 | 102 | 0.153 | 0 |
| TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0046330 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0046330 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TLR3 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0046330 | Not Cancer Driver | No | 123 | 0.136 | 0 | 0 | 0.0 | 1 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0046330 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0046330 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0046330 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF19 | TNFRSF19 | Q9NS68 | Tumor necrosis factor receptor superfamily member 19 | chr13 | GO:0046330 | Not Cancer Driver | No | 72 | 0.17 | 103 | 19 | 0.184 | 0 |
| TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0046330 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
| TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | GO:0046330 | Not Cancer Driver | No | 254 | 0.187 | 781 | 156 | 0.2 | 0 |
| TPD52L1_ENST00000534000 | TPD52L1 | Q16890 | Tumor protein D53 | chr6 | GO:0046330 | Not Cancer Driver | No | 46 | 0.225 | 170 | 38 | 0.224 | 0 |
| TRAF1 | TRAF1 | Q13077 | TNF receptor-associated factor 1 | chr9 | GO:0046330 | Not Cancer Driver | No | 51 | 0.123 | 63 | 9 | 0.143 | 0 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0046330 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | GO:0046330 | Compendium | Yes | 61 | 0.107 | 101 | 9 | 0.089 | 1 |
| TRAF4 | TRAF4 | Q9BUZ4 | TNF receptor-associated factor 4 | chr17 | GO:0046330 | Not Cancer Driver | No | 42 | 0.089 | 27 | 1 | 0.037 | 0 |
| TRAF5_ENST00000336184 | TRAF5 | O00463 | TNF receptor-associated factor 5 | chr1 | GO:0046330 | Not Cancer Driver | No | 61 | 0.11 | 59 | 5 | 0.085 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0046330 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0046330 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| UNC5CL | UNC5CL | Q8IV45 | UNC5C-like protein | chr6 | GO:0046330 | Not Cancer Driver | No | 74 | 0.143 | 70 | 13 | 0.186 | 0 |
| WNT16 | WNT16 | Q9UBV4 | Protein Wnt-16 | chr7 | GO:0046330 | Not Cancer Driver | No | 59 | 0.162 | 28 | 9 | 0.321 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0046330 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0046330 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| WNT7B | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0046330 | Not Cancer Driver | No | 55 | 0.158 | 11 | 1 | 0.091 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0046330 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |
| ZNF622 | ZNF622 | Q969S3 | Zinc finger protein 622 | chr5 | GO:0046330 | Not Cancer Driver | No | 66 | 0.138 | 220 | 33 | 0.15 | 0 |