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Total number of protein in "GO:0044270" GO term:  223

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AASDHPPT AASDHPPT Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase chr11 GO:0044270 Not Cancer Driver No 52 0.168 27 2 0.074 0
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0044270 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCC2 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 GO:0044270 Not Cancer Driver No 202 0.131 102 23 0.225 4
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0044270 Not Cancer Driver No 106 0.142 75 5 0.067 138
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 GO:0044270 Not Cancer Driver No 63 0.147 51 3 0.059 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0044270 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACMSD ACMSD Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 GO:0044270 Not Cancer Driver No 65 0.193 9 2 0.222 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0044270 Not Cancer Driver No 43 0.113 77 16 0.208 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0044270 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADA2 ADA2 Q9NZK5 Adenosine deaminase 2 chr22 GO:0044270 Not Cancer Driver No 97 0.19 1 0 0.0 10
ADAL ADAL Q6DHV7 Adenosine deaminase-like protein chr15 GO:0044270 Not Cancer Driver No 33 0.093 57 9 0.158 0
AFMID_ENST00000409257 AFMID Q63HM1 Kynurenine formamidase chr17 GO:0044270 Not Cancer Driver No 46 0.152 12 1 0.083 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0044270 Not Cancer Driver No 56 0.283 0 0 0.0 8
ALDH1L1_ENST00000393434 ALDH1L1 O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase chr3 GO:0044270 Not Cancer Driver No 159 0.176 87 19 0.218 0
ALDH1L2 ALDH1L2 Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase chr12 GO:0044270 Not Cancer Driver No 108 0.117 81 12 0.148 0
ALDH6A1 ALDH6A1 Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial chr14 GO:0044270 Not Cancer Driver No 54 0.101 83 11 0.133 1
AMBP AMBP P02760 Protein AMBP chr9 GO:0044270 Not Cancer Driver No 57 0.162 61 15 0.246 0
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0044270 Not Cancer Driver No 132 0.172 207 38 0.184 10
ANG ANG P03950 Angiogenin chr14 GO:0044270 Not Cancer Driver No 19 0.129 36 2 0.056 14
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0044270 Not Cancer Driver No 62 0.263 13 1 0.077 0
APOBEC2 APOBEC2 Q9Y235 C->U-editing enzyme APOBEC-2 chr6 GO:0044270 Not Cancer Driver No 38 0.17 36 3 0.083 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0044270 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOBEC3B APOBEC3B Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B chr22 GO:0044270 Census Yes 61 0.16 1 0 0.0 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 GO:0044270 Not Cancer Driver No 28 0.147 2 0 0.0 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 GO:0044270 Not Cancer Driver No 43 0.111 3 0 0.0 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0044270 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0044270 Not Cancer Driver No 61 0.159 0 0 0.0 0
APOBEC3H_ENST00000613677 APOBEC3H Q6NTF7 DNA dC->dU-editing enzyme APOBEC-3H chr22 GO:0044270 Not Cancer Driver No 39 0.195 0 0 0.0 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0044270 Census, Compendium Yes 469 0.153 225 39 0.173 41
BHMT BHMT Q93088 Betaine--homocysteine S-methyltransferase 1 chr5 GO:0044270 Not Cancer Driver No 78 0.192 93 12 0.129 0
BLVRA BLVRA P53004 Biliverdin reductase A chr7 GO:0044270 Not Cancer Driver No 34 0.115 6 1 0.167 0
BLVRB BLVRB P30043 Flavin reductase (NADPH) chr19 GO:0044270 Not Cancer Driver No 16 0.078 56 6 0.107 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0044270 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDADC1 CDADC1 Q9BWV3 Cytidine and dCMP deaminase domain-containing protein 1 chr13 GO:0044270 Not Cancer Driver No 52 0.101 122 13 0.107 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:0044270 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0044270 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0044270 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0044270 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0044270 Not Cancer Driver No 36 0.086 71 2 0.028 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0044270 Not Cancer Driver No 118 0.148 204 29 0.142 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0044270 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0044270 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP3A5 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0044270 Not Cancer Driver No 67 0.133 38 5 0.132 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0044270 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0044270 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0044270 Not Cancer Driver No 14 0.082 88 9 0.102 0
DEDD2 DEDD2 Q8WXF8 DNA-binding death effector domain-containing protein 2 chr19 GO:0044270 Not Cancer Driver No 42 0.129 133 25 0.188 0
DERA DERA Q9Y315 Deoxyribose-phosphate aldolase chr12 GO:0044270 Not Cancer Driver No 33 0.104 2 0 0.0 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0044270 Not Cancer Driver No 47 0.142 113 18 0.159 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 GO:0044270 Not Cancer Driver No 37 0.109 27 1 0.037 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0044270 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0044270 Compendium Yes 121 0.126 235 32 0.136 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:0044270 Not Cancer Driver No 111 0.105 139 20 0.144 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0044270 Not Cancer Driver No 114 0.129 264 22 0.083 1
DMGDH DMGDH Q9UI17 Dimethylglycine dehydrogenase, mitochondrial chr5 GO:0044270 Not Cancer Driver No 155 0.179 74 12 0.162 1
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0044270 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0044270 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0044270 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0044270 Not Cancer Driver No 53 0.147 14 1 0.071 0
DNPH1 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0044270 Not Cancer Driver No 15 0.086 49 3 0.061 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0044270 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0044270 Not Cancer Driver No 303 0.296 77 23 0.299 3
DPYS DPYS Q14117 Dihydropyrimidinase chr8 GO:0044270 Not Cancer Driver No 148 0.285 103 28 0.272 5
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0044270 Census, Compendium Yes 175 0.127 682 100 0.147 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0044270 Not Cancer Driver No 19 0.075 128 8 0.062 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0044270 Not Cancer Driver No 46 0.116 143 17 0.119 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0044270 Not Cancer Driver No 86 0.104 208 30 0.144 10
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0044270 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0044270 Not Cancer Driver No 79 0.174 20 4 0.2 0
ENTPD1_ENST00000371205 ENTPD1 P49961 Ectonucleoside triphosphate diphosphohydrolase 1 chr10 GO:0044270 Not Cancer Driver No 63 0.124 16 2 0.125 1
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 GO:0044270 Not Cancer Driver No 36 0.073 32 0 0.0 0
ENTPD3 ENTPD3 O75355 Ectonucleoside triphosphate diphosphohydrolase 3 chr3 GO:0044270 Not Cancer Driver No 64 0.121 14 2 0.143 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0044270 Not Cancer Driver No 67 0.109 26 2 0.077 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0044270 Not Cancer Driver No 41 0.096 6 1 0.167 0
ENTPD6 ENTPD6 O75354 Ectonucleoside triphosphate diphosphohydrolase 6 chr20 GO:0044270 Not Cancer Driver No 68 0.14 41 6 0.146 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0044270 Not Cancer Driver No 90 0.149 26 3 0.115 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0044270 Not Cancer Driver No 46 0.093 5 0 0.0 0
ERI1_ENST00000519292 ERI1 Q8IV48 3'-5' exoribonuclease 1 chr8 GO:0044270 Not Cancer Driver No 40 0.115 78 13 0.167 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0044270 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0044270 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0044270 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0044270 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0044270 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0044270 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0044270 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0044270 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0044270 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0044270 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0044270 Not Cancer Driver No 58 0.132 154 18 0.117 1
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0044270 Census Yes 35 0.092 111 11 0.099 0
FHIT_ENST00000492590 FHIT P49789 Bis(5'-adenosyl)-triphosphatase chr3 GO:0044270 Census, Compendium Yes 35 0.238 45 9 0.2 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0044270 Not Cancer Driver No 28 0.107 0 0 0.0 1
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0044270 Census, Compendium Yes 39 0.104 257 20 0.078 26
GALT GALT P07902 Galactose-1-phosphate uridylyltransferase chr9 GO:0044270 Not Cancer Driver No 42 0.111 149 9 0.06 134
GDA_ENST00000358399 GDA Q9Y2T3 Guanine deaminase chr9 GO:0044270 Not Cancer Driver No 86 0.189 22 7 0.318 0
HAAO HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase chr2 GO:0044270 Not Cancer Driver No 40 0.14 30 2 0.067 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0044270 Not Cancer Driver No 46 0.16 81 13 0.16 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 GO:0044270 Not Cancer Driver No 27 0.085 74 10 0.135 0
HNMT HNMT P50135 Histamine N-methyltransferase chr2 GO:0044270 Not Cancer Driver No 40 0.137 7 0 0.0 2
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0044270 Not Cancer Driver No 22 0.101 3 0 0.0 62
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0044270 Not Cancer Driver No 82 0.203 41 8 0.195 0
IDO2 IDO2 Q6ZQW0 Indoleamine 2,3-dioxygenase 2 chr8 GO:0044270 Not Cancer Driver No 93 0.221 35 5 0.143 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0044270 Not Cancer Driver No 65 0.115 136 14 0.103 0
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0044270 Not Cancer Driver No 20 0.11 6 0 0.0 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 GO:0044270 Not Cancer Driver No 21 0.108 10 1 0.1 1
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0044270 Not Cancer Driver No 77 0.158 0 0 0.0 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0044270 Not Cancer Driver No 103 0.222 20 5 0.25 1
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0044270 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0044270 Not Cancer Driver No 60 0.24 179 32 0.179 0
LSM1 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 GO:0044270 Not Cancer Driver No 21 0.158 6 1 0.167 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0044270 Not Cancer Driver No 61 0.105 268 27 0.101 0
MGAT1_ENST00000446023 MGAT1 P26572 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase chr5 GO:0044270 Not Cancer Driver No 67 0.151 44 2 0.045 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0044270 Not Cancer Driver No 41 0.083 82 0 0.0 0
MPST_ENST00000341116 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 GO:0044270 Not Cancer Driver No 20 0.067 72 8 0.111 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0044270 Not Cancer Driver No 37 0.111 45 2 0.044 1
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0044270 Not Cancer Driver No 37 0.131 15 0 0.0 0
MTHFS MTHFS P49914 5-formyltetrahydrofolate cyclo-ligase chr15 GO:0044270 Not Cancer Driver No 18 0.089 36 6 0.167 2
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0044270 Not Cancer Driver No 73 0.125 136 22 0.162 1
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0044270 Not Cancer Driver No 117 0.112 160 15 0.094 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0044270 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0044270 Not Cancer Driver No 31 0.093 145 14 0.097 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 GO:0044270 Not Cancer Driver No 41 0.125 18 3 0.167 0
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0044270 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0044270 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 GO:0044270 Not Cancer Driver No 136 0.223 253 58 0.229 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0044270 Census Yes 57 0.102 85 8 0.094 0
NT5C3B NT5C3B Q969T7 7-methylguanosine phosphate-specific 5'-nucleotidase chr17 GO:0044270 Not Cancer Driver No 25 0.083 2 0 0.0 0
NT5E NT5E P21589 5'-nucleotidase chr6 GO:0044270 Not Cancer Driver No 61 0.106 26 2 0.077 1
NT5M NT5M Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial chr17 GO:0044270 Not Cancer Driver No 20 0.088 0 0 0.0 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0044270 Census Yes 38 0.122 147 18 0.122 0
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0044270 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0044270 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0044270 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT13 NUDT13 Q86X67 NAD(P)H pyrophosphatase NUDT13, mitochondrial chr10 GO:0044270 Not Cancer Driver No 40 0.114 19 0 0.0 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0044270 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0044270 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0044270 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT17 NUDT17 P0C025 Nucleoside diphosphate-linked moiety X motif 17 chr1 GO:0044270 Not Cancer Driver No 33 0.101 91 15 0.165 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0044270 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0044270 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0044270 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0044270 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0044270 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0044270 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 GO:0044270 Not Cancer Driver No 27 0.123 90 11 0.122 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0044270 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0044270 Not Cancer Driver No 22 0.093 69 10 0.145 0
NUDT9 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 GO:0044270 Not Cancer Driver No 27 0.077 177 16 0.09 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0044270 Not Cancer Driver No 37 0.107 71 12 0.169 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0044270 Not Cancer Driver No 71 0.111 197 22 0.112 2
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0044270 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0044270 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0044270 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0044270 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0044270 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0044270 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4C PDE4C Q08493 cAMP-specific 3',5'-cyclic phosphodiesterase 4C chr19 GO:0044270 Not Cancer Driver No 122 0.171 362 61 0.169 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0044270 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0044270 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDE7A PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 GO:0044270 Not Cancer Driver No 49 0.102 30 7 0.233 0
PDE7B PDE7B Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B chr6 GO:0044270 Not Cancer Driver No 74 0.164 47 7 0.149 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0044270 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDE8B PDE8B O95263 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B chr5 GO:0044270 Not Cancer Driver No 144 0.163 208 19 0.091 1
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0044270 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0044270 Not Cancer Driver No 14 0.047 38 4 0.105 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0044270 Not Cancer Driver No 38 0.099 67 10 0.149 0
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 GO:0044270 Not Cancer Driver No 79 0.157 42 10 0.238 0
PM20D2 PM20D2 Q8IYS1 Xaa-Arg dipeptidase chr6 GO:0044270 Not Cancer Driver No 39 0.089 79 7 0.089 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0044270 Not Cancer Driver No 38 0.131 29 2 0.069 5
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0044270 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0044270 Not Cancer Driver No 15 0.087 15 1 0.067 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0044270 Not Cancer Driver No 161 0.157 495 75 0.152 3
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0044270 Not Cancer Driver No 62 0.092 93 4 0.043 9
PRPF18 PRPF18 Q99633 Pre-mRNA-splicing factor 18 chr10 GO:0044270 Not Cancer Driver No 52 0.152 93 18 0.194 0
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0044270 Not Cancer Driver No 29 0.129 3 0 0.0 0
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 GO:0044270 Not Cancer Driver No 29 0.098 7 1 0.143 0
RBM7_ENST00000540163 RBM7 Q9Y580 RNA-binding protein 7 chr11 GO:0044270 Not Cancer Driver No 36 0.135 194 27 0.139 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0044270 Not Cancer Driver No 34 0.081 298 26 0.087 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0044270 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0044270 Not Cancer Driver No 42 0.14 31 3 0.097 7
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0044270 Not Cancer Driver No 104 0.166 91 14 0.154 13
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0044270 Not Cancer Driver No 36 0.05 80 4 0.05 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0044270 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLCO1B1 SLCO1B1 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 chr12 GO:0044270 Not Cancer Driver No 177 0.256 33 3 0.091 0
SLCO1B3_ENST00000381545 SLCO1B3 Q9NPD5 Solute carrier organic anion transporter family member 1B3 chr12 GO:0044270 Not Cancer Driver No 208 0.296 35 8 0.229 0
SLCO2B1 SLCO2B1 O94956 Solute carrier organic anion transporter family member 2B1 chr11 GO:0044270 Not Cancer Driver No 114 0.161 99 18 0.182 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0044270 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0044270 Not Cancer Driver No 66 0.072 61 3 0.049 4
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0044270 Not Cancer Driver No 33 0.122 46 2 0.043 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0044270 Census Yes 127 0.14 258 48 0.186 0
SSB SSB P05455 Lupus La protein chr2 GO:0044270 Not Cancer Driver No 39 0.096 181 18 0.099 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0044270 Not Cancer Driver No 72 0.092 140 12 0.086 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0044270 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 GO:0044270 Not Cancer Driver No 64 0.158 31 9 0.29 1
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0044270 Not Cancer Driver No 65 0.134 75 15 0.2 0
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0044270 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0044270 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 GO:0044270 Not Cancer Driver No 208 0.116 1272 152 0.119 6
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0044270 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0044270 Not Cancer Driver No 33 0.14 23 6 0.261 0
TRIR TRIR Q9BQ61 Telomerase RNA component interacting RNase chr19 GO:0044270 Not Cancer Driver No 17 0.097 176 17 0.097 0
TST_ENST00000249042 TST Q16762 Thiosulfate sulfurtransferase chr22 GO:0044270 Not Cancer Driver No 32 0.108 56 6 0.107 0
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 GO:0044270 Not Cancer Driver No 164 0.105 59 3 0.051 3
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0044270 Not Cancer Driver No 97 0.111 410 50 0.122 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0044270 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0044270 Not Cancer Driver No 159 0.106 659 74 0.112 0
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 GO:0044270 Not Cancer Driver No 28 0.058 143 7 0.049 5
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0044270 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT1A4 UGT1A4 P22310 UDP-glucuronosyltransferase 1A4 chr2 GO:0044270 Not Cancer Driver No 99 0.185 11 2 0.182 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0044270 Not Cancer Driver No 34 0.109 96 13 0.135 1
UPB1 UPB1 Q9UBR1 Beta-ureidopropionase chr22 GO:0044270 Not Cancer Driver No 66 0.172 22 7 0.318 8
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0044270 Not Cancer Driver No 146 0.129 329 36 0.109 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0044270 Not Cancer Driver No 47 0.152 13 3 0.231 0
UPP2_ENST00000005756 UPP2 O95045 Uridine phosphorylase 2 chr2 GO:0044270 Not Cancer Driver No 55 0.174 5 1 0.2 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0044270 Not Cancer Driver No 88 0.109 186 16 0.086 16
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0044270 Not Cancer Driver No 279 0.209 134 24 0.179 1
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0044270 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0044270 Not Cancer Driver No 129 0.136 427 63 0.148 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0044270 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 GO:0044270 Census Yes 81 0.115 503 56 0.111 1
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0044270 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0044270 Compendium Yes 57 0.169 212 30 0.142 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0044270 Not Cancer Driver No 38 0.083 291 27 0.093 0