Total number of protein in "GO:0043491" GO term: 36
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADTRP_ENST00000414691 | ADTRP | Q96IZ2 | Androgen-dependent TFPI-regulating protein | chr6 | GO:0043491 | Not Cancer Driver | No | 41 | 0.178 | 2 | 0 | 0.0 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0043491 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0043491 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| CCL2 | CCL2 | P13500 | C-C motif chemokine 2 | chr17 | GO:0043491 | Not Cancer Driver | No | 20 | 0.202 | 15 | 5 | 0.333 | 0 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0043491 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0043491 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0043491 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0043491 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0043491 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0043491 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0043491 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | GO:0043491 | Compendium | Yes | 44 | 0.106 | 172 | 11 | 0.064 | 4 |
| MERTK_ENST00000421804 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | GO:0043491 | Not Cancer Driver | No | 175 | 0.175 | 159 | 31 | 0.195 | 3 |
| MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | GO:0043491 | Not Cancer Driver | No | 45 | 0.108 | 145 | 16 | 0.11 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0043491 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0043491 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0043491 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
| PEAR1 | PEAR1 | Q5VY43 | Platelet endothelial aggregation receptor 1 | chr1 | GO:0043491 | Not Cancer Driver | No | 152 | 0.147 | 233 | 42 | 0.18 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0043491 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0043491 | Not Cancer Driver | No | 51 | 0.111 | 149 | 20 | 0.134 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0043491 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0043491 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0043491 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| RPS6KB2 | RPS6KB2 | Q9UBS0 | Ribosomal protein S6 kinase beta-2 | chr11 | GO:0043491 | Not Cancer Driver | No | 54 | 0.112 | 194 | 16 | 0.082 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0043491 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0043491 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0043491 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0043491 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0043491 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0043491 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | GO:0043491 | Not Cancer Driver | No | 19 | 0.079 | 14 | 0 | 0.0 | 0 |
| TMEM100 | TMEM100 | Q9NV29 | Transmembrane protein 100 | chr17 | GO:0043491 | Not Cancer Driver | No | 29 | 0.216 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043491 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0043491 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0043491 | Not Cancer Driver | No | 119 | 0.134 | 197 | 17 | 0.086 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0043491 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |