Total number of protein in "GO:0043266" GO term: 89
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC8_ENST00000389817 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0043266 | Not Cancer Driver | No | 255 | 0.161 | 138 | 23 | 0.167 | 97 |
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:0043266 | Not Cancer Driver | No | 227 | 0.254 | 131 | 29 | 0.221 | 9 |
| ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0043266 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0043266 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| AKAP6 | AKAP6 | Q13023 | A-kinase anchor protein 6 | chr14 | GO:0043266 | Not Cancer Driver | No | 383 | 0.165 | 1456 | 240 | 0.165 | 0 |
| AKAP9 | AKAP9 | Q99996 | A-kinase anchor protein 9 | chr7 | GO:0043266 | Census | Yes | 474 | 0.121 | 2281 | 268 | 0.117 | 1 |
| ALG10B | ALG10B | Q5I7T1 | Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase | chr12 | GO:0043266 | Not Cancer Driver | No | 90 | 0.19 | 0 | 0 | 0.0 | 0 |
| AMIGO1_ENST00000369862 | AMIGO1 | Q86WK6 | Amphoterin-induced protein 1 | chr1 | GO:0043266 | Not Cancer Driver | No | 46 | 0.093 | 85 | 7 | 0.082 | 0 |
| ANK2 | ANK2 | Q01484 | Ankyrin-2 | chr4 | GO:0043266 | Not Cancer Driver | No | 770 | 0.195 | 2844 | 566 | 0.199 | 4 |
| ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:0043266 | Not Cancer Driver | No | 860 | 0.196 | 3054 | 579 | 0.19 | 0 |
| ANO6_ENST00000320560 | ANO6 | Q4KMQ2 | Anoctamin-6 | chr12 | GO:0043266 | Not Cancer Driver | No | 134 | 0.147 | 80 | 11 | 0.138 | 0 |
| ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0043266 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | GO:0043266 | Not Cancer Driver | No | 38 | 0.125 | 55 | 9 | 0.164 | 0 |
| ATP1B2 | ATP1B2 | P14415 | Sodium/potassium-transporting ATPase subunit beta-2 | chr17 | GO:0043266 | Not Cancer Driver | No | 40 | 0.138 | 16 | 6 | 0.375 | 0 |
| ATP1B3 | ATP1B3 | P54709 | Sodium/potassium-transporting ATPase subunit beta-3 | chr3 | GO:0043266 | Not Cancer Driver | No | 36 | 0.129 | 6 | 1 | 0.167 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0043266 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
| CAB39 | CAB39 | Q9Y376 | Calcium-binding protein 39 | chr2 | GO:0043266 | Not Cancer Driver | No | 31 | 0.091 | 43 | 5 | 0.116 | 0 |
| CACNA1D_ENST00000350061 | CACNA1D | Q01668 | Voltage-dependent L-type calcium channel subunit alpha-1D | chr3 | GO:0043266 | Census, Compendium | Yes | 342 | 0.158 | 736 | 126 | 0.171 | 2 |
| CASQ2 | CASQ2 | O14958 | Calsequestrin-2 | chr1 | GO:0043266 | Not Cancer Driver | No | 74 | 0.185 | 75 | 16 | 0.213 | 4 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0043266 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0043266 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CRBN | CRBN | Q96SW2 | Protein cereblon | chr3 | GO:0043266 | Not Cancer Driver | No | 52 | 0.118 | 76 | 10 | 0.132 | 1 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0043266 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0043266 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| DRD1 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0043266 | Not Cancer Driver | No | 73 | 0.164 | 30 | 4 | 0.133 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0043266 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0043266 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| EDN3_ENST00000371028 | EDN3 | P14138 | Endothelin-3 | chr20 | GO:0043266 | Not Cancer Driver | No | 69 | 0.29 | 140 | 44 | 0.314 | 3 |
| FHL1_ENST00000345434 | FHL1 | Q13642 | Four and a half LIM domains protein 1 | chrX | GO:0043266 | Not Cancer Driver | No | 56 | 0.173 | 51 | 7 | 0.137 | 13 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0043266 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FXYD2 | FXYD2 | P54710 | Sodium/potassium-transporting ATPase subunit gamma | chr11 | GO:0043266 | Not Cancer Driver | No | 2 | 0.03 | 20 | 2 | 0.1 | 1 |
| GAL | GAL | P22466 | Galanin peptides | chr11 | GO:0043266 | Not Cancer Driver | No | 17 | 0.138 | 36 | 2 | 0.056 | 1 |
| GALR2 | GALR2 | O43603 | Galanin receptor type 2 | chr17 | GO:0043266 | Not Cancer Driver | No | 40 | 0.103 | 0 | 0 | 0.0 | 0 |
| GCK_ENST00000403799 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0043266 | Not Cancer Driver | No | 88 | 0.189 | 73 | 14 | 0.192 | 107 |
| HCRT | HCRT | O43612 | Orexin | chr17 | GO:0043266 | Not Cancer Driver | No | 3 | 0.023 | 45 | 0 | 0.0 | 1 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0043266 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0043266 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KCNA1 | KCNA1 | Q09470 | Potassium voltage-gated channel subfamily A member 1 | chr12 | GO:0043266 | Not Cancer Driver | No | 176 | 0.356 | 69 | 34 | 0.493 | 17 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:0043266 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KCNAB1 | KCNAB1 | Q14722 | Voltage-gated potassium channel subunit beta-1 | chr3 | GO:0043266 | Not Cancer Driver | No | 89 | 0.212 | 83 | 23 | 0.277 | 0 |
| KCNC1_ENST00000379472 | KCNC1 | P48547 | Potassium voltage-gated channel subfamily C member 1 | chr11 | GO:0043266 | Not Cancer Driver | No | 91 | 0.178 | 110 | 18 | 0.164 | 1 |
| KCNC2 | KCNC2 | Q96PR1 | Potassium voltage-gated channel subfamily C member 2 | chr12 | GO:0043266 | Not Cancer Driver | No | 161 | 0.252 | 255 | 63 | 0.247 | 0 |
| KCNE1_ENST00000399284 | KCNE1 | P15382 | Potassium voltage-gated channel subfamily E member 1 | chr21 | GO:0043266 | Not Cancer Driver | No | 35 | 0.271 | 24 | 10 | 0.417 | 9 |
| KCNE2 | KCNE2 | Q9Y6J6 | Potassium voltage-gated channel subfamily E member 2 | chr21 | GO:0043266 | Not Cancer Driver | No | 25 | 0.203 | 2 | 0 | 0.0 | 5 |
| KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | GO:0043266 | Not Cancer Driver | No | 28 | 0.272 | 24 | 2 | 0.083 | 0 |
| KCNE4 | KCNE4 | Q8WWG9 | Potassium voltage-gated channel subfamily E member 4 | chr2 | GO:0043266 | Not Cancer Driver | No | 26 | 0.118 | 94 | 18 | 0.191 | 0 |
| KCNE5 | KCNE5 | Q9UJ90 | Potassium voltage-gated channel subfamily E regulatory beta subunit 5 | chrX | GO:0043266 | Not Cancer Driver | No | 35 | 0.246 | 68 | 26 | 0.382 | 0 |
| KCNG1 | KCNG1 | Q9UIX4 | Potassium voltage-gated channel subfamily G member 1 | chr20 | GO:0043266 | Not Cancer Driver | No | 123 | 0.24 | 50 | 12 | 0.24 | 0 |
| KCNH2 | KCNH2 | Q12809 | Potassium voltage-gated channel subfamily H member 2 | chr7 | GO:0043266 | Not Cancer Driver | No | 189 | 0.163 | 466 | 50 | 0.107 | 117 |
| KCNIP2_ENST00000356640 | KCNIP2 | Q9NS61 | Kv channel-interacting protein 2 | chr10 | GO:0043266 | Not Cancer Driver | No | 34 | 0.126 | 89 | 16 | 0.18 | 0 |
| KCNJ2_ENST00000535240 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0043266 | Not Cancer Driver | No | 103 | 0.241 | 49 | 11 | 0.224 | 12 |
| KCNMB1 | KCNMB1 | Q16558 | Calcium-activated potassium channel subunit beta-1 | chr5 | GO:0043266 | Not Cancer Driver | No | 49 | 0.257 | 0 | 0 | 0.0 | 0 |
| KCNN4 | KCNN4 | O15554 | Intermediate conductance calcium-activated potassium channel protein 4 | chr19 | GO:0043266 | Not Cancer Driver | No | 60 | 0.141 | 31 | 6 | 0.194 | 3 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0043266 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KCNRG | KCNRG | Q8N5I3 | Potassium channel regulatory protein | chr13 | GO:0043266 | Not Cancer Driver | No | 44 | 0.162 | 47 | 7 | 0.149 | 0 |
| KCNS1 | KCNS1 | Q96KK3 | Potassium voltage-gated channel subfamily S member 1 | chr20 | GO:0043266 | Not Cancer Driver | No | 52 | 0.099 | 64 | 3 | 0.047 | 0 |
| KCNS2_ENST00000521839 | KCNS2 | Q9ULS6 | Potassium voltage-gated channel subfamily S member 2 | chr8 | GO:0043266 | Not Cancer Driver | No | 124 | 0.26 | 29 | 7 | 0.241 | 0 |
| KEL | KEL | P23276 | Kell blood group glycoprotein | chr7 | GO:0043266 | Compendium | Yes | 232 | 0.317 | 117 | 39 | 0.333 | 0 |
| KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | GO:0043266 | Census, Compendium | Yes | 122 | 0.127 | 586 | 67 | 0.114 | 0 |
| KLHL24_ENST00000242810 | KLHL24 | Q6TFL4 | Kelch-like protein 24 | chr3 | GO:0043266 | Not Cancer Driver | No | 102 | 0.17 | 17 | 6 | 0.353 | 0 |
| LRRC26 | LRRC26 | Q2I0M4 | Leucine-rich repeat-containing protein 26 | chr9 | GO:0043266 | Not Cancer Driver | No | 3 | 0.009 | 41 | 2 | 0.049 | 0 |
| LRRC38 | LRRC38 | Q5VT99 | Leucine-rich repeat-containing protein 38 | chr1 | GO:0043266 | Not Cancer Driver | No | 24 | 0.082 | 12 | 2 | 0.167 | 0 |
| LRRC52 | LRRC52 | Q8N7C0 | Leucine-rich repeat-containing protein 52 | chr1 | GO:0043266 | Not Cancer Driver | No | 61 | 0.195 | 15 | 4 | 0.267 | 0 |
| MTNR1B | MTNR1B | P49286 | Melatonin receptor type 1B | chr11 | GO:0043266 | Not Cancer Driver | No | 104 | 0.287 | 8 | 1 | 0.125 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0043266 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0043266 | Not Cancer Driver | No | 126 | 0.129 | 463 | 60 | 0.13 | 4 |
| NETO1 | NETO1 | Q8TDF5 | Neuropilin and tolloid-like protein 1 | chr18 | GO:0043266 | Not Cancer Driver | No | 186 | 0.349 | 103 | 33 | 0.32 | 0 |
| NETO2 | NETO2 | Q8NC67 | Neuropilin and tolloid-like protein 2 | chr16 | GO:0043266 | Not Cancer Driver | No | 71 | 0.135 | 102 | 22 | 0.216 | 0 |
| NOS1AP | NOS1AP | O75052 | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein | chr1 | GO:0043266 | Not Cancer Driver | No | 94 | 0.186 | 255 | 53 | 0.208 | 1 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0043266 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0043266 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0043266 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0043266 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | GO:0043266 | Not Cancer Driver | No | 69 | 0.131 | 208 | 29 | 0.139 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0043266 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| RGS4_ENST00000367909 | RGS4 | P49798 | Regulator of G-protein signaling 4 | chr1 | GO:0043266 | Not Cancer Driver | No | 68 | 0.332 | 5 | 4 | 0.8 | 0 |
| RGS7_ENST00000366563 | RGS7 | P49802 | Regulator of G-protein signaling 7 | chr1 | GO:0043266 | Census, Compendium | Yes | 196 | 0.396 | 150 | 50 | 0.333 | 0 |
| RNF207 | RNF207 | Q6ZRF8 | RING finger protein 207 | chr1 | GO:0043266 | Not Cancer Driver | No | 48 | 0.076 | 198 | 13 | 0.066 | 0 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0043266 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0043266 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0043266 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0043266 | Not Cancer Driver | No | 7 | 0.06 | 47 | 4 | 0.085 | 3 |
| VIP | VIP | P01282 | VIP peptides | chr6 | GO:0043266 | Not Cancer Driver | No | 58 | 0.341 | 77 | 25 | 0.325 | 0 |
| WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0043266 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
| WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | GO:0043266 | Census, Compendium | Yes | 223 | 0.097 | 1868 | 167 | 0.089 | 0 |
| WNK3_ENST00000375159 | WNK3 | Q9BYP7 | Serine/threonine-protein kinase WNK3 | chrX | GO:0043266 | Not Cancer Driver | No | 281 | 0.156 | 1281 | 200 | 0.156 | 0 |
| WNK4 | WNK4 | Q96J92 | Serine/threonine-protein kinase WNK4 | chr17 | GO:0043266 | Compendium | Yes | 178 | 0.143 | 916 | 126 | 0.138 | 4 |
| WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0043266 | Not Cancer Driver | No | 112 | 0.129 | 422 | 57 | 0.135 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0043266 | Census | Yes | 32 | 0.125 | 41 | 3 | 0.073 | 0 |