Filter in search result
Please select a valid state.

Total number of protein in "GO:0043254" GO term:  258

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0043254 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0043254 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043254 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0043254 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADD2_ENST00000407644 ADD2 P35612 Beta-adducin chr2 GO:0043254 Not Cancer Driver No 157 0.216 423 104 0.246 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 GO:0043254 Not Cancer Driver No 95 0.135 381 48 0.126 1
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0043254 Not Cancer Driver No 36 0.118 87 9 0.103 0
AKAIN1_ENST00000434239 AKAIN1 P0CW23 A-kinase anchor protein inhibitor 1 chr18 GO:0043254 Not Cancer Driver No 5 0.072 70 6 0.086 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0043254 Census Yes 474 0.121 2281 268 0.117 1
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0043254 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANKRA2 ANKRA2 Q9H9E1 Ankyrin repeat family A protein 2 chr5 GO:0043254 Not Cancer Driver No 31 0.099 97 11 0.113 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0043254 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANKRD53 ANKRD53 Q8N9V6 Ankyrin repeat domain-containing protein 53 chr2 GO:0043254 Not Cancer Driver No 57 0.108 252 21 0.083 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0043254 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0043254 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0043254 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0043254 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL3 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0043254 Not Cancer Driver No 16 0.088 0 0 0.0 2
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 GO:0043254 Not Cancer Driver No 183 0.162 584 108 0.185 0
ATAT1_ENST00000376485 ATAT1 Q5SQI0 Alpha-tubulin N-acetyltransferase 1 chr6 GO:0043254 Not Cancer Driver No 31 0.074 271 20 0.074 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0043254 Compendium Yes 160 0.126 1136 139 0.122 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0043254 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0043254 Census, Compendium Yes 338 0.128 106 14 0.132 1
AVIL AVIL O75366 Advillin chr12 GO:0043254 Not Cancer Driver No 91 0.111 138 17 0.123 2
BBS10 BBS10 Q8TAM1 Bardet-Biedl syndrome 10 protein chr12 GO:0043254 Not Cancer Driver No 78 0.108 67 11 0.164 24
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0043254 Not Cancer Driver No 69 0.112 83 9 0.108 0
CALY CALY Q9NYX4 Neuron-specific vesicular protein calcyon chr10 GO:0043254 Not Cancer Driver No 8 0.037 133 5 0.038 0
CAMSAP1 CAMSAP1 Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 chr9 GO:0043254 Not Cancer Driver No 208 0.13 1129 158 0.14 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 GO:0043254 Not Cancer Driver No 176 0.118 1025 127 0.124 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 GO:0043254 Not Cancer Driver No 132 0.106 889 81 0.091 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0043254 Not Cancer Driver No 45 0.129 95 7 0.074 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 GO:0043254 Not Cancer Driver No 40 0.14 41 2 0.049 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 GO:0043254 Not Cancer Driver No 37 0.129 19 0 0.0 0
CAPZA3 CAPZA3 Q96KX2 F-actin-capping protein subunit alpha-3 chr12 GO:0043254 Not Cancer Driver No 87 0.291 0 0 0.0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 GO:0043254 Not Cancer Driver No 33 0.119 66 3 0.045 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0043254 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0043254 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0043254 Not Cancer Driver No 154 0.107 669 75 0.112 4
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0043254 Not Cancer Driver No 27 0.179 0 0 0.0 25
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0043254 Not Cancer Driver No 75 0.159 12 3 0.25 3
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0043254 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0043254 Census Yes 166 0.2 186 35 0.188 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0043254 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0043254 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0043254 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0043254 Census, Compendium Yes 19 0.096 198 19 0.096 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0043254 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0043254 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0043254 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CLIP3_ENST00000593074 CLIP3 Q96DZ5 CAP-Gly domain-containing linker protein 3 chr19 GO:0043254 Not Cancer Driver No 78 0.143 218 22 0.101 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0043254 Not Cancer Driver No 69 0.154 156 27 0.173 0
CPTP CPTP Q5TA50 Ceramide-1-phosphate transfer protein chr1 GO:0043254 Not Cancer Driver No 16 0.075 4 0 0.0 0
CRBN CRBN Q96SW2 Protein cereblon chr3 GO:0043254 Not Cancer Driver No 52 0.118 76 10 0.132 1
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0043254 Not Cancer Driver No 22 0.126 59 11 0.186 4
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0043254 Not Cancer Driver No 11 0.076 34 3 0.088 0
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0043254 Not Cancer Driver No 8 0.099 64 7 0.109 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0043254 Not Cancer Driver No 11 0.101 0 0 0.0 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043254 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0043254 Not Cancer Driver No 163 0.195 598 127 0.212 1
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0043254 Census Yes 172 0.135 817 111 0.136 11
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0043254 Census, Compendium Yes 133 0.201 301 47 0.156 18
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0043254 Not Cancer Driver No 53 0.075 125 12 0.096 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0043254 Not Cancer Driver No 58 0.218 47 8 0.17 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0043254 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 GO:0043254 Not Cancer Driver No 19 0.127 25 4 0.16 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 GO:0043254 Not Cancer Driver No 35 0.095 31 0 0.0 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0043254 Not Cancer Driver No 135 0.177 447 73 0.163 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0043254 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0043254 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EML2_ENST00000245925 EML2 O95834 Echinoderm microtubule-associated protein-like 2 chr19 GO:0043254 Not Cancer Driver No 97 0.149 20 3 0.15 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0043254 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0043254 Not Cancer Driver No 106 0.129 459 54 0.118 0
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 GO:0043254 Not Cancer Driver No 133 0.126 250 39 0.156 0
FBLIM1_ENST00000375771 FBLIM1 Q8WUP2 Filamin-binding LIM protein 1 chr1 GO:0043254 Not Cancer Driver No 54 0.145 176 28 0.159 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0043254 Not Cancer Driver No 100 0.148 65 8 0.123 2
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0043254 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0043254 Census Yes 103 0.125 245 34 0.139 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0043254 Not Cancer Driver No 46 0.1 134 12 0.09 0
FLII FLII Q13045 Protein flightless-1 homolog chr17 GO:0043254 Not Cancer Driver No 128 0.101 206 32 0.155 0
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0043254 Not Cancer Driver No 58 0.118 81 5 0.062 0
GBA2 GBA2 Q9HCG7 Non-lysosomal glucosylceramidase chr9 GO:0043254 Not Cancer Driver No 96 0.104 157 12 0.076 3
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0043254 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0043254 Not Cancer Driver No 106 0.181 170 21 0.124 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0043254 Not Cancer Driver No 65 0.15 288 42 0.146 62
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0043254 Not Cancer Driver No 67 0.088 434 42 0.097 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0043254 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0043254 Not Cancer Driver No 76 0.097 316 28 0.089 2
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0043254 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0043254 Not Cancer Driver No 28 0.206 51 14 0.275 3
HCFC1 HCFC1 P51610 Host cell factor 1 chrX GO:0043254 Not Cancer Driver No 280 0.138 1345 181 0.135 1
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0043254 Not Cancer Driver No 112 0.213 124 25 0.202 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0043254 Not Cancer Driver No 178 0.147 409 59 0.144 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0043254 Not Cancer Driver No 37 0.132 226 32 0.142 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0043254 Not Cancer Driver No 94 0.088 524 34 0.065 0
HJURP HJURP Q8NCD3 Holliday junction recognition protein chr2 GO:0043254 Not Cancer Driver No 108 0.144 572 85 0.149 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0043254 Not Cancer Driver No 25 0.116 203 20 0.099 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0043254 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0043254 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0043254 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0043254 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0043254 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0043254 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0043254 Not Cancer Driver No 149 0.231 251 52 0.207 0
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0043254 Not Cancer Driver No 22 0.247 10 2 0.2 0
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0043254 Not Cancer Driver No 108 0.151 76 13 0.171 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0043254 Not Cancer Driver No 13 0.097 0 0 0.0 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0043254 Not Cancer Driver No 49 0.153 84 12 0.143 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0043254 Not Cancer Driver No 102 0.101 629 42 0.067 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0043254 Not Cancer Driver No 25 0.049 359 12 0.033 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0043254 Not Cancer Driver No 9 0.05 45 1 0.022 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0043254 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0043254 Not Cancer Driver No 85 0.244 180 41 0.228 0
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0043254 Not Cancer Driver No 50 0.161 62 11 0.177 2
KIAA1211 CRACD Q6ZU35 Capping protein-inhibiting regulator of actin dynamics chr4 GO:0043254 Not Cancer Driver No 245 0.199 1210 241 0.199 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0043254 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIF9_ENST00000452770 KIF9 Q9HAQ2 Kinesin-like protein KIF9 chr3 GO:0043254 Not Cancer Driver No 94 0.119 213 42 0.197 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0043254 Census, Compendium Yes 161 0.142 788 100 0.127 0
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0043254 Not Cancer Driver No 43 0.098 28 2 0.071 34
LCMT1 LCMT1 Q9UIC8 Leucine carboxyl methyltransferase 1 chr16 GO:0043254 Not Cancer Driver No 43 0.129 2 0 0.0 0
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0043254 Census Yes 99 0.158 73 11 0.151 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0043254 Not Cancer Driver No 66 0.216 191 39 0.204 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 GO:0043254 Not Cancer Driver No 30 0.182 11 1 0.091 0
LMOD1 LMOD1 P29536 Leiomodin-1 chr1 GO:0043254 Not Cancer Driver No 97 0.162 499 80 0.16 0
LMOD2 LMOD2 Q6P5Q4 Leiomodin-2 chr7 GO:0043254 Not Cancer Driver No 94 0.172 451 79 0.175 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0043254 Not Cancer Driver No 99 0.177 456 84 0.184 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0043254 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0043254 Compendium Yes 367 0.201 1726 340 0.197 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0043254 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0043254 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0043254 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0043254 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0043254 Not Cancer Driver No 128 0.169 750 126 0.168 18
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0043254 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED25 MED25 Q71SY5 Mediator of RNA polymerase II transcription subunit 25 chr19 GO:0043254 Not Cancer Driver No 103 0.138 432 54 0.125 2
MEFV MEFV O15553 Pyrin chr16 GO:0043254 Not Cancer Driver No 196 0.251 397 119 0.3 47
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0043254 Census, Compendium Yes 226 0.163 62 15 0.242 19
MSN MSN P26038 Moesin chrX GO:0043254 Census, Compendium Yes 108 0.187 286 56 0.196 1
MTPN MTPN P58546 Myotrophin chr7 GO:0043254 Not Cancer Driver No 11 0.093 11 3 0.273 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0043254 Census, Compendium Yes 37 0.125 47 1 0.021 2
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 GO:0043254 Not Cancer Driver No 33 0.112 11 0 0.0 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 GO:0043254 Not Cancer Driver No 30 0.101 29 2 0.069 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0043254 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NCLN NCLN Q969V3 Nicalin chr19 GO:0043254 Not Cancer Driver No 42 0.075 38 4 0.105 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0043254 Not Cancer Driver No 35 0.116 23 0 0.0 0
NIN NIN Q8N4C6 Ninein chr14 GO:0043254 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0043254 Not Cancer Driver No 176 0.165 147 33 0.224 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0043254 Not Cancer Driver No 59 0.123 391 41 0.105 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0043254 Not Cancer Driver No 56 0.122 179 30 0.168 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0043254 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OCLN OCLN Q16625 Occludin chr5 GO:0043254 Not Cancer Driver No 54 0.103 244 21 0.086 1
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0043254 Not Cancer Driver No 91 0.245 30 3 0.1 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0043254 Not Cancer Driver No 57 0.167 21 2 0.095 3
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0043254 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0043254 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0043254 Not Cancer Driver No 119 0.117 320 34 0.106 0
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0043254 Not Cancer Driver No 73 0.114 321 36 0.112 2
PFN4 PFN4 Q8NHR9 Profilin-4 chr2 GO:0043254 Not Cancer Driver No 17 0.132 0 0 0.0 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0043254 Not Cancer Driver No 122 0.048 471 26 0.055 12
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0043254 Not Cancer Driver No 57 0.098 99 13 0.131 23
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0043254 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0043254 Not Cancer Driver No 81 0.231 39 9 0.231 0
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 GO:0043254 Not Cancer Driver No 45 0.157 196 34 0.173 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0043254 Not Cancer Driver No 60 0.157 134 24 0.179 0
PREB PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 GO:0043254 Not Cancer Driver No 56 0.134 91 10 0.11 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0043254 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0043254 Not Cancer Driver No 45 0.132 268 32 0.119 7
PRUNE1 PRUNE1 Q86TP1 Exopolyphosphatase PRUNE1 chr1 GO:0043254 Not Cancer Driver No 43 0.095 93 14 0.151 4
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0043254 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0043254 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0043254 Census, Compendium Yes 129 0.218 260 38 0.146 60
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:0043254 Not Cancer Driver No 28 0.315 0 0 0.0 0
PYDC2 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:0043254 Not Cancer Driver No 20 0.206 26 5 0.192 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0043254 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0043254 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0043254 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0043254 Not Cancer Driver No 36 0.175 35 5 0.143 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0043254 Not Cancer Driver No 10 0.054 42 5 0.119 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0043254 Not Cancer Driver No 26 0.141 14 3 0.214 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0043254 Not Cancer Driver No 73 0.076 505 48 0.095 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0043254 Census, Compendium Yes 140 0.151 282 32 0.113 22
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0043254 Not Cancer Driver No 71 0.122 297 37 0.125 1
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0043254 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0043254 Not Cancer Driver No 58 0.112 225 21 0.093 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0043254 Not Cancer Driver No 14 0.074 117 7 0.06 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:0043254 Not Cancer Driver No 27 0.133 33 2 0.061 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0043254 Not Cancer Driver No 22 0.091 48 4 0.083 0
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 GO:0043254 Not Cancer Driver No 23 0.116 4 0 0.0 0
SAR1B SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 GO:0043254 Not Cancer Driver No 17 0.086 4 0 0.0 5
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0043254 Not Cancer Driver No 100 0.14 170 35 0.206 0
SELP SELP P16109 P-selectin chr1 GO:0043254 Not Cancer Driver No 226 0.272 14 2 0.143 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 GO:0043254 Not Cancer Driver No 120 0.108 612 59 0.096 0
SEPT8 SEPTIN8 Q92599 Septin-8 chr5 GO:0043254 Not Cancer Driver No 52 0.108 172 17 0.099 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0043254 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0043254 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLAIN1_ENST00000466548 SLAIN1 Q8ND83 SLAIN motif-containing protein 1 chr13 GO:0043254 Not Cancer Driver No 62 0.109 485 58 0.12 0
SLAIN2 SLAIN2 Q9P270 SLAIN motif-containing protein 2 chr4 GO:0043254 Not Cancer Driver No 62 0.107 562 60 0.107 0
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 GO:0043254 Not Cancer Driver No 210 0.304 89 29 0.326 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0043254 Not Cancer Driver No 38 0.077 248 7 0.028 7
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0043254 Not Cancer Driver No 21 0.15 107 13 0.121 5
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0043254 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOST SOST Q9BQB4 Sclerostin chr17 GO:0043254 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0043254 Compendium Yes 86 0.169 495 82 0.166 18
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0043254 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 GO:0043254 Not Cancer Driver No 315 0.127 980 114 0.116 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0043254 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0043254 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0043254 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPTBN5 SPTBN5 Q9NRC6 Spectrin beta chain, non-erythrocytic 5 chr15 GO:0043254 Not Cancer Driver No 314 0.085 1274 118 0.093 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0043254 Not Cancer Driver No 328 0.153 562 70 0.125 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0043254 Census Yes 53 0.099 130 11 0.085 1
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0043254 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0043254 Not Cancer Driver No 34 0.19 122 23 0.189 0
STMP1 STMP1 E0CX11 Short transmembrane mitochondrial protein 1 chr7 GO:0043254 Not Cancer Driver No 1 0.021 12 0 0.0 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0043254 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0043254 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0043254 Not Cancer Driver No 38 0.132 155 20 0.129 2
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0043254 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP5 STXBP5 Q5T5C0 Syntaxin-binding protein 5 chr6 GO:0043254 Not Cancer Driver No 128 0.111 344 46 0.134 0
STXBP6_ENST00000419632 STXBP6 Q8NFX7 Syntaxin-binding protein 6 chr14 GO:0043254 Not Cancer Driver No 33 0.157 51 6 0.118 0
SVIL SVIL O95425 Supervillin chr10 GO:0043254 Not Cancer Driver No 308 0.139 1423 192 0.135 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0043254 Not Cancer Driver No 16 0.208 77 16 0.208 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0043254 Not Cancer Driver No 156 0.131 60 9 0.15 11
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0043254 Not Cancer Driver No 117 0.262 201 54 0.269 2
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0043254 Not Cancer Driver No 63 0.144 220 34 0.155 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0043254 Not Cancer Driver No 87 0.104 331 39 0.118 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0043254 Not Cancer Driver No 69 0.141 207 30 0.145 2
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0043254 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0043254 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0043254 Not Cancer Driver No 99 0.124 1 0 0.0 0
TMC8 TMC8 Q8IU68 Transmembrane channel-like protein 8 chr17 GO:0043254 Not Cancer Driver No 61 0.084 107 10 0.093 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 GO:0043254 Not Cancer Driver No 41 0.114 195 29 0.149 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0043254 Not Cancer Driver No 33 0.094 216 22 0.102 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 GO:0043254 Not Cancer Driver No 40 0.114 190 24 0.126 0
TMOD4 TMOD4 Q9NZQ9 Tropomodulin-4 chr1 GO:0043254 Not Cancer Driver No 37 0.107 218 22 0.101 0
TMSB10 TMSB10 P63313 Thymosin beta-10 chr2 GO:0043254 Not Cancer Driver No 2 0.045 44 2 0.045 0
TMSB15A TMSB15A P0CG34 Thymosin beta-15A chrX GO:0043254 Not Cancer Driver No 8 0.178 45 8 0.178 0
TMSB15B TMSB15B P0CG35 Thymosin beta-15B chrX GO:0043254 Not Cancer Driver No 7 0.156 45 7 0.156 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0043254 Census Yes 7 0.159 44 7 0.159 0
TMSB4Y TMSB4Y O14604 Thymosin beta-4, Y-chromosomal chrY GO:0043254 Not Cancer Driver No 1 0.023 44 1 0.023 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043254 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 GO:0043254 Not Cancer Driver No 230 0.134 703 101 0.144 3
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0043254 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0043254 Not Cancer Driver No 75 0.109 507 60 0.118 4
TRAPPC12 TRAPPC12 Q8WVT3 Trafficking protein particle complex subunit 12 chr2 GO:0043254 Not Cancer Driver No 88 0.12 318 31 0.097 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0043254 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0043254 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 GO:0043254 Not Cancer Driver No 91 0.205 61 16 0.262 2
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0043254 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0043254 Not Cancer Driver No 34 0.097 59 8 0.136 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0043254 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0043254 Not Cancer Driver No 214 0.135 448 77 0.172 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 GO:0043254 Not Cancer Driver No 33 0.097 2 0 0.0 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 GO:0043254 Not Cancer Driver No 35 0.119 9 1 0.111 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0043254 Not Cancer Driver No 124 0.15 222 38 0.171 0
VILL_ENST00000383759 VILL O15195 Villin-like protein chr3 GO:0043254 Not Cancer Driver No 100 0.117 222 28 0.126 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0043254 Not Cancer Driver No 68 0.085 99 9 0.091 1
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 GO:0043254 Not Cancer Driver No 90 0.068 1204 89 0.074 0
ZNF827 ZNF827 Q17R98 Zinc finger protein 827 chr4 GO:0043254 Not Cancer Driver No 158 0.146 754 123 0.163 0