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Total number of protein in "GO:0043177" GO term:  123

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0043177 Not Cancer Driver No 388 0.158 342 62 0.181 0
ALKBH3 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0043177 Not Cancer Driver No 42 0.147 157 25 0.159 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0043177 Not Cancer Driver No 17 0.106 1 0 0.0 0
CAD CAD P27708 CAD protein chr2 GO:0043177 Not Cancer Driver No 287 0.129 368 52 0.141 1
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:0043177 Not Cancer Driver No 27 0.082 39 5 0.128 0
CEP104 CEP104 O60308 Centrosomal protein of 104 kDa chr1 GO:0043177 Not Cancer Driver No 116 0.125 306 43 0.141 0
CRABP1 CRABP1 P29762 Cellular retinoic acid-binding protein 1 chr15 GO:0043177 Not Cancer Driver No 17 0.124 22 5 0.227 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0043177 Not Cancer Driver No 27 0.196 23 6 0.261 0
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0043177 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0043177 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0043177 Not Cancer Driver No 32 0.061 56 6 0.107 0
CYP2W1 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 GO:0043177 Not Cancer Driver No 51 0.104 55 6 0.109 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0043177 Not Cancer Driver No 125 0.203 71 17 0.239 3
DBT DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 GO:0043177 Not Cancer Driver No 64 0.133 81 11 0.136 3
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0043177 Not Cancer Driver No 16 0.086 12 2 0.167 2
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0043177 Not Cancer Driver No 35 0.082 206 8 0.039 2
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 GO:0043177 Not Cancer Driver No 52 0.128 201 17 0.085 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0043177 Not Cancer Driver No 33 0.138 13 0 0.0 0
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0043177 Not Cancer Driver No 34 0.268 0 0 0.0 0
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0043177 Not Cancer Driver No 22 0.165 3 0 0.0 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0043177 Not Cancer Driver No 15 0.111 4 4 1.0 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0043177 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0043177 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOLR3 FOLR3 P41439 Folate receptor gamma chr11 GO:0043177 Not Cancer Driver No 58 0.237 15 4 0.267 0
FTCD_ENST00000291670 FTCD O95954 Formimidoyltransferase-cyclodeaminase chr21 GO:0043177 Not Cancer Driver No 86 0.159 44 36 0.818 2
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:0043177 Not Cancer Driver No 152 0.149 112 7 0.062 22
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0043177 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0043177 Not Cancer Driver No 106 0.235 58 14 0.241 0
GLRA3 GLRA3 O75311 Glycine receptor subunit alpha-3 chr4 GO:0043177 Not Cancer Driver No 132 0.284 32 11 0.344 0
GLRB GLRB P48167 Glycine receptor subunit beta chr4 GO:0043177 Not Cancer Driver No 112 0.225 66 12 0.182 4
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0043177 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUD2 GLUD2 P49448 Glutamate dehydrogenase 2, mitochondrial chrX GO:0043177 Not Cancer Driver No 145 0.26 117 37 0.316 0
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0043177 Not Cancer Driver No 25 0.085 0 0 0.0 3
GPR143 GPR143 P51810 G-protein coupled receptor 143 chrX GO:0043177 Not Cancer Driver No 47 0.116 83 14 0.169 34
GPR31 GPR31 O00270 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor chr6 GO:0043177 Not Cancer Driver No 52 0.163 14 3 0.214 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0043177 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0043177 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0043177 Not Cancer Driver No 308 0.276 179 22 0.123 0
GRIN3B GRIN3B O60391 Glutamate receptor ionotropic, NMDA 3B chr19 GO:0043177 Not Cancer Driver No 90 0.086 299 23 0.077 0
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0043177 Not Cancer Driver No 316 0.345 91 31 0.341 1
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 GO:0043177 Not Cancer Driver No 9 0.063 4 0 0.0 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0043177 Not Cancer Driver No 45 0.306 7 2 0.286 5
HBD HBD P02042 Hemoglobin subunit delta chr11 GO:0043177 Not Cancer Driver No 56 0.381 7 2 0.286 0
HBE1_ENST00000396895 HBE1 P02100 Hemoglobin subunit epsilon chr11 GO:0043177 Not Cancer Driver No 44 0.299 0 0 0.0 0
HBG1 HBG1 P69891 Hemoglobin subunit gamma-1 chr11 GO:0043177 Not Cancer Driver No 23 0.156 2 0 0.0 0
HBG2 HBG2 P69892 Hemoglobin subunit gamma-2 chr11 GO:0043177 Not Cancer Driver No 65 0.442 2 0 0.0 6
HBM HBM Q6B0K9 Hemoglobin subunit mu chr16 GO:0043177 Not Cancer Driver No 9 0.064 0 0 0.0 0
HBQ1 HBQ1 P09105 Hemoglobin subunit theta-1 chr16 GO:0043177 Not Cancer Driver No 10 0.07 0 0 0.0 0
HBZ HBZ P02008 Hemoglobin subunit zeta chr16 GO:0043177 Not Cancer Driver No 9 0.063 0 0 0.0 0
HLCS HLCS P50747 Biotin--protein ligase chr21 GO:0043177 Not Cancer Driver No 95 0.131 158 15 0.095 23
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0043177 Census, Compendium Yes 14 0.118 34 4 0.118 0
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 GO:0043177 Not Cancer Driver No 318 0.128 255 20 0.078 0
IZUMO1R IZUMO1R A6ND01 Sperm-egg fusion protein Juno chr11 GO:0043177 Not Cancer Driver No 41 0.164 0 0 0.0 0
LCN12 LCN12 Q6JVE5 Epididymal-specific lipocalin-12 chr9 GO:0043177 Not Cancer Driver No 15 0.078 28 1 0.036 0
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0043177 Not Cancer Driver No 54 0.235 2 0 0.0 1
MCCC1 MCCC1 Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial chr3 GO:0043177 Not Cancer Driver No 94 0.13 162 17 0.105 33
MTHFS MTHFS P49914 5-formyltetrahydrofolate cyclo-ligase chr15 GO:0043177 Not Cancer Driver No 18 0.089 36 6 0.167 2
NAGS NAGS Q8N159 N-acetylglutamate synthase, mitochondrial chr17 GO:0043177 Not Cancer Driver No 35 0.066 116 6 0.052 6
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0043177 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0043177 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0043177 Not Cancer Driver No 168 0.14 347 38 0.11 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0043177 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0043177 Not Cancer Driver No 66 0.159 101 1 0.01 5
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:0043177 Not Cancer Driver No 44 0.081 156 6 0.038 0
OGFOD2 OGFOD2 Q6N063 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 chr12 GO:0043177 Not Cancer Driver No 32 0.091 34 1 0.029 0
OGFOD3_ENST00000313056 OGFOD3 Q6PK18 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 chr17 GO:0043177 Not Cancer Driver No 52 0.163 51 5 0.098 0
OXER1 OXER1 Q8TDS5 Oxoeicosanoid receptor 1 chr2 GO:0043177 Not Cancer Driver No 42 0.099 38 3 0.079 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0043177 Not Cancer Driver No 59 0.148 14 1 0.071 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 GO:0043177 Not Cancer Driver No 91 0.124 177 18 0.102 0
P3H2 P3H2 Q8IVL5 Prolyl 3-hydroxylase 2 chr3 GO:0043177 Not Cancer Driver No 131 0.185 160 24 0.15 1
P3H3 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 GO:0043177 Not Cancer Driver No 84 0.114 307 40 0.13 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 GO:0043177 Not Cancer Driver No 65 0.122 54 8 0.148 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 GO:0043177 Not Cancer Driver No 66 0.123 82 12 0.146 2
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 GO:0043177 Not Cancer Driver No 70 0.129 17 2 0.118 0
P4HTM_ENST00000383729 P4HTM Q9NXG6 Transmembrane prolyl 4-hydroxylase chr3 GO:0043177 Not Cancer Driver No 76 0.151 144 20 0.139 1
PADI4 PADI4 Q9UM07 Protein-arginine deiminase type-4 chr1 GO:0043177 Not Cancer Driver No 115 0.173 114 23 0.202 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0043177 Not Cancer Driver No 129 0.133 254 37 0.146 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 GO:0043177 Not Cancer Driver No 185 0.157 172 27 0.157 9
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 GO:0043177 Not Cancer Driver No 102 0.14 42 14 0.333 16
PHYH PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 GO:0043177 Not Cancer Driver No 54 0.16 40 4 0.1 14
PITPNA PITPNA Q00169 Phosphatidylinositol transfer protein alpha isoform chr17 GO:0043177 Not Cancer Driver No 26 0.096 82 7 0.085 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 GO:0043177 Not Cancer Driver No 86 0.118 12 0 0.0 5
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 GO:0043177 Not Cancer Driver No 109 0.148 17 3 0.176 4
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 GO:0043177 Not Cancer Driver No 108 0.146 65 8 0.123 1
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0043177 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0043177 Census Yes 72 0.143 44 4 0.091 3
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0043177 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 GO:0043177 Not Cancer Driver No 72 0.109 41 3 0.073 2
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0043177 Compendium Yes 90 0.195 184 26 0.141 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0043177 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0043177 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0043177 Not Cancer Driver No 18 0.158 76 7 0.092 0
SCP2 SCP2 P22307 Sterol carrier protein 2 chr1 GO:0043177 Not Cancer Driver No 59 0.108 45 2 0.044 0
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 GO:0043177 Not Cancer Driver No 103 0.254 24 17 0.708 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0043177 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0043177 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0043177 Not Cancer Driver No 84 0.171 44 4 0.091 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0043177 Not Cancer Driver No 51 0.106 32 7 0.219 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 GO:0043177 Not Cancer Driver No 57 0.113 58 5 0.086 1
SLC19A1 SLC19A1 P41440 Reduced folate transporter chr21 GO:0043177 Not Cancer Driver No 77 0.13 144 7 0.049 0
SLC46A1 SLC46A1 Q96NT5 Proton-coupled folate transporter chr17 GO:0043177 Not Cancer Driver No 37 0.081 31 0 0.0 13
SRR SRR Q9GZT4 Serine racemase chr17 GO:0043177 Not Cancer Driver No 40 0.118 32 6 0.188 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0043177 Not Cancer Driver No 51 0.176 129 30 0.233 0
THNSL2 THNSL2 Q86YJ6 Threonine synthase-like 2 chr2 GO:0043177 Not Cancer Driver No 73 0.151 51 3 0.059 0
TM4SF5 TM4SF5 O14894 Transmembrane 4 L6 family member 5 chr17 GO:0043177 Not Cancer Driver No 33 0.168 1 0 0.0 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0043177 Not Cancer Driver No 22 0.07 41 0 0.0 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0043177 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0043177 Not Cancer Driver No 172 0.098 228 30 0.132 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0043177 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT1A10 UGT1A10 Q9HAW8 UDP-glucuronosyltransferase 1A10 chr2 GO:0043177 Not Cancer Driver No 114 0.215 11 2 0.182 0
UGT1A3 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0043177 Not Cancer Driver No 98 0.184 11 2 0.182 0
UGT1A4 UGT1A4 P22310 UDP-glucuronosyltransferase 1A4 chr2 GO:0043177 Not Cancer Driver No 99 0.185 11 2 0.182 0
UGT1A6 UGT1A6 P19224 UDP-glucuronosyltransferase 1-6 chr2 GO:0043177 Not Cancer Driver No 96 0.18 11 2 0.182 0
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 GO:0043177 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A8 UGT1A8 Q9HAW9 UDP-glucuronosyltransferase 1A8 chr2 GO:0043177 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A9 UGT1A9 O60656 UDP-glucuronosyltransferase 1A9 chr2 GO:0043177 Not Cancer Driver No 121 0.228 11 2 0.182 0
UGT2B15 UGT2B15 P54855 UDP-glucuronosyltransferase 2B15 chr4 GO:0043177 Not Cancer Driver No 140 0.264 12 4 0.333 0
UGT2B17 UGT2B17 O75795 UDP-glucuronosyltransferase 2B17 chr4 GO:0043177 Compendium Yes 112 0.211 12 1 0.083 0
UGT2B4 UGT2B4 P06133 UDP-glucuronosyltransferase 2B4 chr4 GO:0043177 Not Cancer Driver No 173 0.328 6 5 0.833 0
UGT2B7 UGT2B7 P16662 UDP-glucuronosyltransferase 2B7 chr4 GO:0043177 Not Cancer Driver No 124 0.234 6 0 0.0 0
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0043177 Not Cancer Driver No 34 0.128 7 0 0.0 21
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0043177 Not Cancer Driver No 64 0.15 102 16 0.157 14
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 GO:0043177 Not Cancer Driver No 59 0.124 62 11 0.177 2