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Total number of protein in "GO:0042594" GO term:  108

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0042594 Not Cancer Driver No 61 0.145 41 5 0.122 19
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0042594 Not Cancer Driver No 45 0.105 32 1 0.031 10
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0042594 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADSL ADSL P30566 Adenylosuccinate lyase chr22 GO:0042594 Not Cancer Driver No 68 0.14 36 9 0.25 27
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0042594 Not Cancer Driver No 161 0.214 98 26 0.265 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0042594 Not Cancer Driver No 81 0.144 11 0 0.0 3
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0042594 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0042594 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0042594 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0042594 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0042594 Compendium Yes 77 0.11 53 8 0.151 6
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0042594 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0042594 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0042594 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0042594 Not Cancer Driver No 12 0.063 183 12 0.066 0
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0042594 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0042594 Not Cancer Driver No 90 0.122 321 39 0.121 0
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:0042594 Not Cancer Driver No 61 0.137 35 6 0.171 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0042594 Census, Compendium Yes 115 0.127 512 56 0.109 4
COMT COMT P21964 Catechol O-methyltransferase chr22 GO:0042594 Not Cancer Driver No 21 0.077 5 0 0.0 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0042594 Not Cancer Driver No 85 0.117 443 54 0.122 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0042594 Not Cancer Driver No 368 0.245 73 22 0.301 140
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0042594 Census Yes 29 0.172 160 27 0.169 0
EIF2A EIF2A Q9BY44 Eukaryotic translation initiation factor 2A chr3 GO:0042594 Not Cancer Driver No 51 0.087 162 19 0.117 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0042594 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0042594 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0042594 Not Cancer Driver No 156 0.095 494 44 0.089 2
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0042594 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0042594 Not Cancer Driver No 79 0.12 548 64 0.117 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0042594 Census, Compendium Yes 70 0.104 595 68 0.114 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0042594 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0042594 Not Cancer Driver No 19 0.162 10 1 0.1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0042594 Not Cancer Driver No 11 0.094 2 1 0.5 0
GALP GALP Q9UBC7 Galanin-like peptide chr19 GO:0042594 Not Cancer Driver No 35 0.302 41 15 0.366 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0042594 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0042594 Not Cancer Driver No 327 0.122 117 16 0.137 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0042594 Not Cancer Driver No 35 0.229 68 16 0.235 0
GNPAT GNPAT O15228 Dihydroxyacetone phosphate acyltransferase chr1 GO:0042594 Not Cancer Driver No 86 0.126 6 3 0.5 3
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 GO:0042594 Not Cancer Driver No 52 0.105 51 9 0.176 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0042594 Not Cancer Driver No 7 0.083 4 0 0.0 4
HCRT HCRT O43612 Orexin chr17 GO:0042594 Not Cancer Driver No 3 0.023 45 0 0.0 1
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0042594 Not Cancer Driver No 55 0.158 27 2 0.074 11
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0042594 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0042594 Not Cancer Driver No 70 0.188 290 58 0.2 4
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0042594 Not Cancer Driver No 73 0.112 282 35 0.124 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0042594 Not Cancer Driver No 155 0.197 419 90 0.215 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0042594 Not Cancer Driver No 49 0.153 84 12 0.143 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0042594 Not Cancer Driver No 59 0.132 61 9 0.148 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:0042594 Not Cancer Driver No 44 0.101 21 2 0.095 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0042594 Not Cancer Driver No 133 0.113 97 10 0.103 1
LRP11 LRP11 Q86VZ4 Low-density lipoprotein receptor-related protein 11 chr6 GO:0042594 Not Cancer Driver No 36 0.072 254 20 0.079 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0042594 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 GO:0042594 Not Cancer Driver No 10 0.08 17 1 0.059 0
MAP1LC3B2 MAP1LC3B2 A6NCE7 Microtubule-associated proteins 1A/1B light chain 3 beta 2 chr12 GO:0042594 Not Cancer Driver No 19 0.152 17 7 0.412 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 GO:0042594 Not Cancer Driver No 32 0.218 31 5 0.161 0
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0042594 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0042594 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0042594 Not Cancer Driver No 144 0.108 463 47 0.102 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0042594 Census, Compendium Yes 228 0.377 402 62 0.154 4
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0042594 Not Cancer Driver No 73 0.167 126 21 0.167 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0042594 Not Cancer Driver No 142 0.215 357 77 0.216 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0042594 Not Cancer Driver No 80 0.154 39 5 0.128 11
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX GO:0042594 Not Cancer Driver No 20 0.196 102 20 0.196 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0042594 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0042594 Not Cancer Driver No 91 0.142 139 13 0.094 0
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0042594 Not Cancer Driver No 70 0.17 14 2 0.143 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0042594 Not Cancer Driver No 81 0.172 48 11 0.229 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0042594 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0042594 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0042594 Not Cancer Driver No 193 0.142 315 45 0.143 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0042594 Not Cancer Driver No 2 0.037 23 1 0.043 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0042594 Not Cancer Driver No 181 0.227 609 148 0.243 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0042594 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0042594 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0042594 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0042594 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0042594 Not Cancer Driver No 74 0.151 144 25 0.174 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0042594 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0042594 Not Cancer Driver No 42 0.105 83 5 0.06 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0042594 Not Cancer Driver No 66 0.145 270 44 0.163 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0042594 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0042594 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0042594 Not Cancer Driver No 84 0.171 44 4 0.091 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0042594 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0042594 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0042594 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0042594 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0042594 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0042594 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 GO:0042594 Not Cancer Driver No 77 0.119 116 11 0.095 9
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0042594 Not Cancer Driver No 67 0.124 139 18 0.129 1
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0042594 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0042594 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0042594 Not Cancer Driver No 94 0.225 110 26 0.236 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0042594 Not Cancer Driver No 59 0.143 15 1 0.067 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0042594 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0042594 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 GO:0042594 Not Cancer Driver No 68 0.152 115 13 0.113 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0042594 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0042594 Not Cancer Driver No 22 0.137 74 11 0.149 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0042594 Not Cancer Driver No 100 0.188 11 2 0.182 55
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0042594 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0042594 Not Cancer Driver No 132 0.127 519 84 0.162 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0042594 Not Cancer Driver No 47 0.152 13 3 0.231 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0042594 Not Cancer Driver No 19 0.073 169 9 0.053 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 GO:0042594 Not Cancer Driver No 103 0.148 70 15 0.214 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0042594 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0042594 Not Cancer Driver No 43 0.132 262 34 0.13 0