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Total number of protein in "GO:0035023" GO term:  86

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0035023 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0035023 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0035023 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 GO:0035023 Not Cancer Driver No 108 0.283 285 86 0.302 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0035023 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0035023 Not Cancer Driver No 130 0.279 40 8 0.2 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0035023 Not Cancer Driver No 359 0.128 2091 258 0.123 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0035023 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0035023 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0035023 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0035023 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0035023 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0035023 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0035023 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0035023 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0035023 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF25_ENST00000286494 ARHGEF25 Q86VW2 Rho guanine nucleotide exchange factor 25 chr12 GO:0035023 Not Cancer Driver No 80 0.138 241 35 0.145 0
ARHGEF28_ENST00000426542 ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 chr5 GO:0035023 Not Cancer Driver No 188 0.11 764 88 0.115 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:0035023 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0035023 Not Cancer Driver No 49 0.117 154 13 0.084 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0035023 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0035023 Census, Compendium Yes 146 0.115 603 69 0.114 0
CAVIN4 CAVIN4 Q5BKX8 Caveolae-associated protein 4 chr9 GO:0035023 Not Cancer Driver No 59 0.162 286 45 0.157 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0035023 Not Cancer Driver No 58 0.114 261 23 0.088 0
CDC42SE1_ENST00000540998 CDC42SE1 Q9NRR8 CDC42 small effector protein 1 chr1 GO:0035023 Not Cancer Driver No 10 0.127 70 10 0.143 0
CDC42SE2 CDC42SE2 Q9NRR3 CDC42 small effector protein 2 chr5 GO:0035023 Not Cancer Driver No 1 0.012 57 1 0.018 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0035023 Census Yes 402 0.274 1182 337 0.285 103
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0035023 Census, Compendium Yes 123 0.16 167 23 0.138 3
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0035023 Not Cancer Driver No 331 0.217 922 237 0.257 0
EPS8L1 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0035023 Not Cancer Driver No 116 0.16 521 96 0.184 0
EPS8L2_ENST00000530636 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0035023 Not Cancer Driver No 68 0.095 372 31 0.083 0
EPS8L3_ENST00000361965 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 GO:0035023 Not Cancer Driver No 105 0.177 338 57 0.169 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0035023 Not Cancer Driver No 106 0.129 459 54 0.118 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0035023 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0035023 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0035023 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0035023 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0035023 Not Cancer Driver No 43 0.112 46 4 0.087 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0035023 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0035023 Not Cancer Driver No 43 0.101 122 15 0.123 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:0035023 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:0035023 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0035023 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:0035023 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0035023 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0035023 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:0035023 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0035023 Not Cancer Driver No 70 0.208 0 0 0.0 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0035023 Not Cancer Driver No 173 0.125 974 135 0.139 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0035023 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0035023 Not Cancer Driver No 103 0.129 84 10 0.119 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0035023 Not Cancer Driver No 183 0.135 804 100 0.124 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 GO:0035023 Not Cancer Driver No 107 0.126 531 71 0.134 3
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:0035023 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0035023 Not Cancer Driver No 33 0.1 95 10 0.105 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0035023 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:0035023 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:0035023 Not Cancer Driver No 39 0.113 0 0 0.0 3
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:0035023 Not Cancer Driver No 173 0.152 410 54 0.132 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0035023 Census, Compendium Yes 226 0.163 62 15 0.242 19
MYO9B_ENST00000594824 MYO9B Q13459 Unconventional myosin-IXb chr19 GO:0035023 Not Cancer Driver No 226 0.105 827 80 0.097 0
MYOC MYOC Q99972 Myocilin chr1 GO:0035023 Not Cancer Driver No 92 0.183 196 43 0.219 58
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0035023 Not Cancer Driver No 60 0.101 294 37 0.126 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0035023 Compendium Yes 146 0.158 211 31 0.147 0
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0035023 Not Cancer Driver No 122 0.152 302 42 0.139 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:0035023 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:0035023 Census, Compendium Yes 126 0.351 23 5 0.217 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0035023 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0035023 Census, Compendium Yes 164 0.148 231 44 0.19 7
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:0035023 Not Cancer Driver No 193 0.137 988 150 0.152 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0035023 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0035023 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0035023 Not Cancer Driver No 65 0.099 381 46 0.121 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0035023 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0035023 Not Cancer Driver No 216 0.175 274 55 0.201 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0035023 Not Cancer Driver No 73 0.076 505 48 0.095 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0035023 Not Cancer Driver No 131 0.123 421 76 0.181 0
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0035023 Not Cancer Driver No 74 0.341 29 11 0.379 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0035023 Not Cancer Driver No 353 0.214 1122 234 0.209 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0035023 Not Cancer Driver No 38 0.08 148 17 0.115 5
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 GO:0035023 Not Cancer Driver No 95 0.157 117 13 0.111 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 GO:0035023 Not Cancer Driver No 177 0.159 494 78 0.158 0
STARD8_ENST00000374597 STARD8 Q92502 StAR-related lipid transfer protein 8 chrX GO:0035023 Not Cancer Driver No 145 0.142 574 86 0.15 0
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0035023 Not Cancer Driver No 15 0.101 149 15 0.101 0
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0035023 Not Cancer Driver No 103 0.105 950 99 0.104 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0035023 Not Cancer Driver No 35 0.111 39 5 0.128 0