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Total number of protein in "GO:0032587" GO term:  98

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0032587 Not Cancer Driver No 260 0.121 402 35 0.087 1
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0032587 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADGRE2 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0032587 Not Cancer Driver No 134 0.163 104 22 0.212 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0032587 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIF1L_ENST00000247291 AIF1L Q9BQI0 Allograft inflammatory factor 1-like chr9 GO:0032587 Not Cancer Driver No 9 0.06 44 1 0.023 0
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0032587 Census Yes 77 0.16 84 9 0.107 2
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0032587 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0032587 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0032587 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0032587 Not Cancer Driver No 110 0.097 679 68 0.1 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0032587 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF4 ARHGEF4 Q9NR80 Rho guanine nucleotide exchange factor 4 chr2 GO:0032587 Not Cancer Driver No 114 0.165 287 61 0.213 0
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0032587 Not Cancer Driver No 106 0.157 172 27 0.157 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 GO:0032587 Not Cancer Driver No 136 0.136 250 40 0.16 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0032587 Not Cancer Driver No 165 0.172 685 120 0.175 18
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 GO:0032587 Not Cancer Driver No 21 0.127 4 0 0.0 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0032587 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0032587 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0032587 Not Cancer Driver No 105 0.128 88 7 0.08 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0032587 Not Cancer Driver No 61 0.129 84 13 0.155 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0032587 Not Cancer Driver No 118 0.128 61 10 0.164 2
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0032587 Not Cancer Driver No 118 0.093 692 57 0.082 1
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0032587 Not Cancer Driver No 331 0.217 922 237 0.257 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0032587 Census Yes 138 0.159 270 43 0.159 22
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0032587 Not Cancer Driver No 109 0.236 100 14 0.14 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0032587 Census, Compendium Yes 444 0.367 223 35 0.157 1
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0032587 Not Cancer Driver No 97 0.132 312 45 0.144 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0032587 Compendium Yes 171 0.175 187 39 0.209 3
EPS8L1 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0032587 Not Cancer Driver No 116 0.16 521 96 0.184 0
EPS8L2_ENST00000530636 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0032587 Not Cancer Driver No 68 0.095 372 31 0.083 0
EPS8L3_ENST00000361965 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 GO:0032587 Not Cancer Driver No 105 0.177 338 57 0.169 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0032587 Not Cancer Driver No 106 0.129 459 54 0.118 0
EZR EZR P15311 Ezrin chr6 GO:0032587 Census Yes 66 0.113 295 35 0.119 0
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0032587 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0032587 Not Cancer Driver No 158 0.208 6 2 0.333 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0032587 Not Cancer Driver No 100 0.148 65 8 0.123 2
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0032587 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0032587 Compendium Yes 275 0.188 915 180 0.197 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0032587 Not Cancer Driver No 85 0.161 52 8 0.154 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0032587 Not Cancer Driver No 94 0.088 524 34 0.065 0
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 GO:0032587 Not Cancer Driver No 43 0.089 19 0 0.0 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0032587 Not Cancer Driver No 42 0.094 34 2 0.059 7
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0032587 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0032587 Census Yes 153 0.146 92 9 0.098 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0032587 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0032587 Not Cancer Driver No 124 0.157 66 5 0.076 30
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0032587 Not Cancer Driver No 291 0.214 1337 290 0.217 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0032587 Not Cancer Driver No 183 0.135 804 100 0.124 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 GO:0032587 Not Cancer Driver No 114 0.124 404 58 0.144 0
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0032587 Census Yes 99 0.158 73 11 0.151 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0032587 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MTMR6 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 GO:0032587 Not Cancer Driver No 87 0.14 68 16 0.235 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0032587 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0032587 Not Cancer Driver No 62 0.083 582 49 0.084 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0032587 Not Cancer Driver No 176 0.136 342 41 0.12 3
NF2 NF2 P35240 Merlin chr22 GO:0032587 Census, Compendium Yes 69 0.116 252 26 0.103 16
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0032587 Not Cancer Driver No 11 0.072 10 0 0.0 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0032587 Not Cancer Driver No 56 0.126 318 47 0.148 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0032587 Not Cancer Driver No 51 0.105 301 27 0.09 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0032587 Not Cancer Driver No 57 0.105 299 30 0.1 2
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0032587 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0032587 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0032587 Not Cancer Driver No 37 0.228 96 24 0.25 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0032587 Not Cancer Driver No 14 0.047 38 4 0.105 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0032587 Not Cancer Driver No 74 0.132 216 29 0.134 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0032587 Not Cancer Driver No 98 0.147 360 60 0.167 1
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0032587 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0032587 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0032587 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0032587 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0032587 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 GO:0032587 Not Cancer Driver No 55 0.134 341 46 0.135 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0032587 Not Cancer Driver No 47 0.058 695 35 0.05 0
PSD PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:0032587 Not Cancer Driver No 173 0.169 714 130 0.182 0
PSD2 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:0032587 Not Cancer Driver No 155 0.201 398 87 0.219 0
PSD3_ENST00000440756 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 GO:0032587 Not Cancer Driver No 146 0.139 645 94 0.146 0
PSD4 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:0032587 Not Cancer Driver No 157 0.149 739 103 0.139 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0032587 Not Cancer Driver No 184 0.138 401 61 0.152 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0032587 Not Cancer Driver No 41 0.158 1 0 0.0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0032587 Census, Compendium Yes 66 0.344 2 1 0.5 6
RASGRP2_ENST00000377497 RASGRP2 Q7LDG7 RAS guanyl-releasing protein 2 chr11 GO:0032587 Not Cancer Driver No 98 0.161 88 15 0.17 4
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0032587 Census, Compendium Yes 99 0.513 46 13 0.283 2
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0032587 Not Cancer Driver No 22 0.091 48 4 0.083 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0032587 Not Cancer Driver No 110 0.128 440 72 0.164 0
SH3YL1 SH3YL1 Q96HL8 SH3 domain-containing YSC84-like protein 1 chr2 GO:0032587 Not Cancer Driver No 35 0.102 108 11 0.102 0
SNTG1 SNTG1 Q9NSN8 Gamma-1-syntrophin chr8 GO:0032587 Not Cancer Driver No 204 0.395 3 1 0.333 0
SPATA13_ENST00000382095 SPATA13 Q96N96 Spermatogenesis-associated protein 13 chr13 GO:0032587 Not Cancer Driver No 68 0.104 263 32 0.122 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0032587 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0032587 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0032587 Census Yes 53 0.099 130 11 0.085 1
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0032587 Not Cancer Driver No 31 0.145 73 6 0.082 0
THEM4 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 GO:0032587 Not Cancer Driver No 19 0.079 14 0 0.0 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0032587 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLN1 TLN1 Q9Y490 Talin-1 chr9 GO:0032587 Not Cancer Driver No 278 0.109 1109 126 0.114 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0032587 Not Cancer Driver No 33 0.116 234 29 0.124 8
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0032587 Not Cancer Driver No 142 0.163 231 34 0.147 44
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0032587 Not Cancer Driver No 50 0.143 52 3 0.058 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:0032587 Not Cancer Driver No 147 0.132 550 81 0.147 0