Total number of protein in "GO:0032436" GO term: 92
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0032436 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ANKIB1 | ANKIB1 | Q9P2G1 | Ankyrin repeat and IBR domain-containing protein 1 | chr7 | GO:0032436 | Not Cancer Driver | No | 141 | 0.129 | 577 | 78 | 0.135 | 0 |
| ARIH1 | ARIH1 | Q9Y4X5 | E3 ubiquitin-protein ligase ARIH1 | chr15 | GO:0032436 | Not Cancer Driver | No | 46 | 0.083 | 119 | 7 | 0.059 | 0 |
| ARIH2 | ARIH2 | O95376 | E3 ubiquitin-protein ligase ARIH2 | chr3 | GO:0032436 | Not Cancer Driver | No | 64 | 0.13 | 85 | 11 | 0.129 | 0 |
| AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | GO:0032436 | Not Cancer Driver | No | 36 | 0.089 | 178 | 21 | 0.118 | 0 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0032436 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | GO:0032436 | Not Cancer Driver | No | 17 | 0.081 | 112 | 9 | 0.08 | 0 |
| BBS7 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | GO:0032436 | Not Cancer Driver | No | 99 | 0.138 | 56 | 8 | 0.143 | 4 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | GO:0032436 | Not Cancer Driver | No | 37 | 0.15 | 104 | 14 | 0.135 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0032436 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CBFA2T3 | CBFA2T3 | O75081 | Protein CBFA2T3 | chr16 | GO:0032436 | Census, Compendium | Yes | 83 | 0.127 | 502 | 70 | 0.139 | 0 |
| CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | GO:0032436 | Not Cancer Driver | No | 44 | 0.088 | 198 | 15 | 0.076 | 0 |
| CDC20B | CDC20B | Q86Y33 | Cell division cycle protein 20 homolog B | chr5 | GO:0032436 | Not Cancer Driver | No | 99 | 0.191 | 152 | 24 | 0.158 | 0 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0032436 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CHFR | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0032436 | Not Cancer Driver | No | 85 | 0.128 | 341 | 54 | 0.158 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:0032436 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| COP1 | COP1 | Q8NHY2 | E3 ubiquitin-protein ligase COP1 | chr1 | GO:0032436 | Not Cancer Driver | No | 106 | 0.145 | 147 | 11 | 0.075 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | GO:0032436 | Not Cancer Driver | No | 44 | 0.131 | 46 | 3 | 0.065 | 0 |
| CSNK1D | CSNK1D | P48730 | Casein kinase I isoform delta | chr17 | GO:0032436 | Not Cancer Driver | No | 59 | 0.142 | 132 | 16 | 0.121 | 2 |
| CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0032436 | Not Cancer Driver | No | 62 | 0.149 | 133 | 18 | 0.135 | 0 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0032436 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DDA1 | DDA1 | Q9BW61 | DET1- and DDB1-associated protein 1 | chr19 | GO:0032436 | Not Cancer Driver | No | 10 | 0.098 | 70 | 9 | 0.129 | 0 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | GO:0032436 | Not Cancer Driver | No | 34 | 0.108 | 181 | 23 | 0.127 | 0 |
| DET1_ENST00000268148 | DET1 | Q7L5Y6 | DET1 homolog | chr15 | GO:0032436 | Not Cancer Driver | No | 97 | 0.176 | 42 | 12 | 0.286 | 0 |
| DNAJB2 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | GO:0032436 | Not Cancer Driver | No | 51 | 0.157 | 239 | 40 | 0.167 | 1 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0032436 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| ELOB_ENST00000409906 | ELOB | Q15370 | Elongin-B | chr16 | GO:0032436 | Not Cancer Driver | No | 13 | 0.11 | 69 | 10 | 0.145 | 0 |
| FBXO22 | FBXO22 | Q8NEZ5 | F-box only protein 22 | chr15 | GO:0032436 | Not Cancer Driver | No | 65 | 0.161 | 15 | 3 | 0.2 | 0 |
| FBXW8 | FBXW8 | Q8N3Y1 | F-box/WD repeat-containing protein 8 | chr12 | GO:0032436 | Not Cancer Driver | No | 68 | 0.114 | 120 | 4 | 0.033 | 0 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | GO:0032436 | Not Cancer Driver | No | 74 | 0.149 | 184 | 30 | 0.163 | 0 |
| GABARAP | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | GO:0032436 | Not Cancer Driver | No | 9 | 0.077 | 11 | 0 | 0.0 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0032436 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0032436 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0032436 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0032436 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0032436 | Not Cancer Driver | No | 274 | 0.105 | 991 | 108 | 0.109 | 0 |
| HERPUD1 | HERPUD1 | Q15011 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein | chr16 | GO:0032436 | Census | Yes | 38 | 0.097 | 248 | 17 | 0.069 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0032436 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0032436 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
| HSPBP1 | HSPBP1 | Q9NZL4 | Hsp70-binding protein 1 | chr19 | GO:0032436 | Not Cancer Driver | No | 29 | 0.081 | 130 | 7 | 0.054 | 0 |
| KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0032436 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
| KLHL40 | KLHL40 | Q2TBA0 | Kelch-like protein 40 | chr3 | GO:0032436 | Not Cancer Driver | No | 108 | 0.174 | 44 | 8 | 0.182 | 13 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0032436 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MAPK9 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0032436 | Not Cancer Driver | No | 59 | 0.139 | 90 | 8 | 0.089 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0032436 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | GO:0032436 | Not Cancer Driver | No | 45 | 0.108 | 145 | 16 | 0.11 | 0 |
| NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0032436 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
| NKD2 | NKD2 | Q969F2 | Protein naked cuticle homolog 2 | chr5 | GO:0032436 | Not Cancer Driver | No | 64 | 0.142 | 451 | 64 | 0.142 | 0 |
| NOP53 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:0032436 | Not Cancer Driver | No | 59 | 0.123 | 391 | 41 | 0.105 | 0 |
| NUB1_ENST00000470229 | NUB1 | Q9Y5A7 | NEDD8 ultimate buster 1 | chr7 | GO:0032436 | Not Cancer Driver | No | 52 | 0.085 | 180 | 15 | 0.083 | 0 |
| PIAS1_ENST00000249636 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0032436 | Not Cancer Driver | No | 80 | 0.123 | 241 | 43 | 0.178 | 0 |
| PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0032436 | Not Cancer Driver | No | 87 | 0.144 | 119 | 13 | 0.109 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0032436 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PRICKLE1_ENST00000640055 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0032436 | Not Cancer Driver | No | 146 | 0.176 | 485 | 91 | 0.188 | 3 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0032436 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0032436 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0032436 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0032436 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | GO:0032436 | Not Cancer Driver | No | 50 | 0.138 | 283 | 41 | 0.145 | 0 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0032436 | Not Cancer Driver | No | 10 | 0.093 | 18 | 1 | 0.056 | 0 |
| RCHY1 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | GO:0032436 | Not Cancer Driver | No | 33 | 0.126 | 23 | 0 | 0.0 | 0 |
| RFPL1 | RFPL1 | O75677 | Ret finger protein-like 1 | chr22 | GO:0032436 | Not Cancer Driver | No | 73 | 0.23 | 28 | 5 | 0.179 | 0 |
| RNF14 | RNF14 | Q9UBS8 | E3 ubiquitin-protein ligase RNF14 | chr5 | GO:0032436 | Not Cancer Driver | No | 52 | 0.11 | 40 | 8 | 0.2 | 0 |
| RNF144A | RNF144A | P50876 | E3 ubiquitin-protein ligase RNF144A | chr2 | GO:0032436 | Not Cancer Driver | No | 63 | 0.216 | 0 | 0 | 0.0 | 0 |
| RNF144B | RNF144B | Q7Z419 | E3 ubiquitin-protein ligase RNF144B | chr6 | GO:0032436 | Not Cancer Driver | No | 32 | 0.106 | 4 | 1 | 0.25 | 0 |
| RNF180 | RNF180 | Q86T96 | E3 ubiquitin-protein ligase RNF180 | chr5 | GO:0032436 | Not Cancer Driver | No | 80 | 0.135 | 190 | 26 | 0.137 | 0 |
| RNF19A | RNF19A | Q9NV58 | E3 ubiquitin-protein ligase RNF19A | chr8 | GO:0032436 | Not Cancer Driver | No | 112 | 0.134 | 387 | 55 | 0.142 | 0 |
| RNF19B | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0032436 | Not Cancer Driver | No | 58 | 0.079 | 344 | 24 | 0.07 | 0 |
| RNF217 | RNF217 | Q8TC41 | E3 ubiquitin-protein ligase RNF217 | chr6 | GO:0032436 | Not Cancer Driver | No | 70 | 0.129 | 203 | 13 | 0.064 | 0 |
| SGTA | SGTA | O43765 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha | chr19 | GO:0032436 | Not Cancer Driver | No | 38 | 0.121 | 159 | 23 | 0.145 | 0 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0032436 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0032436 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SH3RF3 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0032436 | Not Cancer Driver | No | 98 | 0.111 | 564 | 53 | 0.094 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0032436 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0032436 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0032436 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SOCS4_ENST00000555846 | SOCS4 | Q8WXH5 | Suppressor of cytokine signaling 4 | chr14 | GO:0032436 | Not Cancer Driver | No | 43 | 0.098 | 136 | 13 | 0.096 | 0 |
| SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0032436 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0032436 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0032436 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | GO:0032436 | Not Cancer Driver | No | 9 | 0.095 | 69 | 6 | 0.087 | 0 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0032436 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TRIB1 | TRIB1 | Q96RU8 | Tribbles homolog 1 | chr8 | GO:0032436 | Not Cancer Driver | No | 47 | 0.126 | 91 | 5 | 0.055 | 0 |
| TRIB2 | TRIB2 | Q92519 | Tribbles homolog 2 | chr2 | GO:0032436 | Not Cancer Driver | No | 64 | 0.187 | 43 | 5 | 0.116 | 0 |
| TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0032436 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
| UBQLN1 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | GO:0032436 | Not Cancer Driver | No | 64 | 0.109 | 543 | 58 | 0.107 | 0 |
| UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | GO:0032436 | Not Cancer Driver | No | 82 | 0.131 | 581 | 79 | 0.136 | 8 |
| USP5 | USP5 | P45974 | Ubiquitin carboxyl-terminal hydrolase 5 | chr12 | GO:0032436 | Not Cancer Driver | No | 117 | 0.136 | 262 | 38 | 0.145 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0032436 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| ZER1 | ZER1 | Q7Z7L7 | Protein zer-1 homolog | chr9 | GO:0032436 | Not Cancer Driver | No | 81 | 0.106 | 34 | 7 | 0.206 | 0 |
| ZFAND2A | ZFAND2A | Q8N6M9 | AN1-type zinc finger protein 2A | chr7 | GO:0032436 | Not Cancer Driver | No | 14 | 0.097 | 8 | 0 | 0.0 | 0 |
| ZYG11B | ZYG11B | Q9C0D3 | Protein zyg-11 homolog B | chr1 | GO:0032436 | Not Cancer Driver | No | 88 | 0.118 | 30 | 7 | 0.233 | 0 |