Total number of protein in "GO:0032200" GO term: 63
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACD_ENST00000620761 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:0032200 | Not Cancer Driver | No | 49 | 0.107 | 256 | 34 | 0.133 | 1 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0032200 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0032200 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
| BRCA2_ENST00000544455 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0032200 | Census, Compendium | Yes | 457 | 0.134 | 1542 | 225 | 0.146 | 46 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0032200 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0032200 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0032200 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0032200 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0032200 | Compendium | Yes | 178 | 0.116 | 988 | 118 | 0.119 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0032200 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0032200 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0032200 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0032200 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0032200 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HIST1H3A | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 18 | 0.132 | 51 | 6 | 0.118 | 1 |
| HIST1H3B | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 80 | 0.588 | 51 | 24 | 0.471 | 1 |
| HIST1H3C | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 45 | 0.331 | 51 | 25 | 0.49 | 1 |
| HIST1H3D | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 49 | 0.36 | 51 | 20 | 0.392 | 1 |
| HIST1H3E_ENST00000614911 | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 36 | 0.265 | 51 | 11 | 0.216 | 1 |
| HIST1H3F | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 38 | 0.279 | 51 | 11 | 0.216 | 1 |
| HIST1H3G | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 33 | 0.243 | 51 | 13 | 0.255 | 1 |
| HIST1H3H | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 29 | 0.213 | 51 | 10 | 0.196 | 1 |
| HIST1H3I | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 44 | 0.324 | 51 | 15 | 0.294 | 1 |
| HIST1H3J | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0032200 | Not Cancer Driver | No | 21 | 0.154 | 51 | 10 | 0.196 | 1 |
| HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 15 | 0.146 | 31 | 5 | 0.161 | 0 |
| HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 29 | 0.282 | 31 | 6 | 0.194 | 0 |
| HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 29 | 0.282 | 31 | 7 | 0.226 | 0 |
| HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 32 | 0.311 | 31 | 8 | 0.258 | 0 |
| HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 45 | 0.437 | 31 | 14 | 0.452 | 0 |
| HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 30 | 0.291 | 31 | 7 | 0.226 | 0 |
| HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 22 | 0.214 | 31 | 9 | 0.29 | 0 |
| HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 33 | 0.32 | 31 | 10 | 0.323 | 0 |
| HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 26 | 0.252 | 31 | 9 | 0.29 | 0 |
| HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 44 | 0.427 | 31 | 13 | 0.419 | 0 |
| HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | GO:0032200 | Not Cancer Driver | No | 25 | 0.243 | 31 | 14 | 0.452 | 0 |
| HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | GO:0032200 | Not Cancer Driver | No | 21 | 0.204 | 31 | 7 | 0.226 | 0 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0032200 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| NSMCE2_ENST00000522563 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0032200 | Not Cancer Driver | No | 30 | 0.121 | 119 | 12 | 0.101 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0032200 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
| POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:0032200 | Census, Compendium | Yes | 113 | 0.178 | 31 | 6 | 0.194 | 9 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0032200 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | GO:0032200 | Not Cancer Driver | No | 47 | 0.125 | 18 | 2 | 0.111 | 6 |
| RAD51D_ENST00000394589 | RAD51D | O75771 | DNA repair protein RAD51 homolog 4 | chr17 | GO:0032200 | Not Cancer Driver | No | 34 | 0.104 | 49 | 10 | 0.204 | 0 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0032200 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0032200 | Census, Compendium | Yes | 138 | 0.114 | 608 | 71 | 0.117 | 1 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0032200 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
| RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0032200 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
| SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:0032200 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
| SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:0032200 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
| SMC5 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0032200 | Not Cancer Driver | No | 126 | 0.114 | 378 | 43 | 0.114 | 0 |
| SMC6_ENST00000351948 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0032200 | Not Cancer Driver | No | 128 | 0.117 | 458 | 57 | 0.124 | 0 |
| TEP1 | TEP1 | Q99973 | Telomerase protein component 1 | chr14 | GO:0032200 | Not Cancer Driver | No | 332 | 0.126 | 396 | 67 | 0.169 | 0 |
| TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:0032200 | Not Cancer Driver | No | 63 | 0.144 | 220 | 34 | 0.155 | 0 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0032200 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0032200 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
| TFIP11_ENST00000407148 | TFIP11 | Q9UBB9 | Tuftelin-interacting protein 11 | chr22 | GO:0032200 | Not Cancer Driver | No | 87 | 0.104 | 331 | 39 | 0.118 | 0 |
| TINF2 | TINF2 | Q9BSI4 | TERF1-interacting nuclear factor 2 | chr14 | GO:0032200 | Not Cancer Driver | No | 38 | 0.084 | 190 | 17 | 0.089 | 4 |
| TPRKB_ENST00000272424 | TPRKB | Q9Y3C4 | EKC/KEOPS complex subunit TPRKB | chr2 | GO:0032200 | Not Cancer Driver | No | 20 | 0.114 | 0 | 0 | 0.0 | 2 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0032200 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0032200 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
| WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0032200 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0032200 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0032200 | Not Cancer Driver | No | 24 | 0.069 | 35 | 2 | 0.057 | 1 |