Filter in search result
Please select a valid state.

Total number of protein in "GO:0031667" GO term:  236

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0031667 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0031667 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0031667 Not Cancer Driver No 90 0.183 3 1 0.333 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0031667 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0031667 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0031667 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0031667 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0031667 Not Cancer Driver No 80 0.153 184 39 0.212 113
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0031667 Not Cancer Driver No 161 0.214 98 26 0.265 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0031667 Not Cancer Driver No 25 0.079 124 6 0.048 12
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0031667 Not Cancer Driver No 34 0.116 12 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0031667 Not Cancer Driver No 41 0.127 83 12 0.145 9
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0031667 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0031667 Not Cancer Driver No 81 0.144 11 0 0.0 3
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0031667 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0031667 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0031667 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0031667 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0031667 Compendium Yes 77 0.11 53 8 0.151 6
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0031667 Not Cancer Driver No 143 0.117 293 42 0.143 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0031667 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0031667 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0031667 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0031667 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0031667 Not Cancer Driver No 13 0.13 21 2 0.095 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0031667 Not Cancer Driver No 12 0.063 183 12 0.066 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0031667 Not Cancer Driver No 91 0.211 69 18 0.261 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 GO:0031667 Not Cancer Driver No 28 0.089 144 18 0.125 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0031667 Census Yes 174 0.139 397 59 0.149 6
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0031667 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0031667 Not Cancer Driver No 90 0.122 321 39 0.121 0
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:0031667 Not Cancer Driver No 61 0.137 35 6 0.171 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0031667 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0031667 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0031667 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0031667 Census, Compendium Yes 55 0.186 31 25 0.806 0
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0031667 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0031667 Not Cancer Driver No 17 0.102 44 3 0.068 0
CHSY1 CHSY1 Q86X52 Chondroitin sulfate synthase 1 chr15 GO:0031667 Not Cancer Driver No 95 0.118 137 10 0.073 1
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0031667 Not Cancer Driver No 19 0.087 23 1 0.043 0
CLPS CLPS P04118 Colipase chr6 GO:0031667 Not Cancer Driver No 25 0.223 0 0 0.0 0
CLPSL1 CLPSL1 A2RUU4 Colipase-like protein 1 chr6 GO:0031667 Not Cancer Driver No 18 0.149 0 0 0.0 0
CLPSL2_ENST00000403376 CLPSL2 Q6UWE3 Colipase-like protein 2 chr6 GO:0031667 Not Cancer Driver No 11 0.11 0 0 0.0 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0031667 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COMT COMT P21964 Catechol O-methyltransferase chr22 GO:0031667 Not Cancer Driver No 21 0.077 5 0 0.0 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0031667 Not Cancer Driver No 85 0.117 443 54 0.122 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0031667 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0031667 Not Cancer Driver No 144 0.186 62 10 0.161 15
CSH1 CSH1 P0DML2 Chorionic somatomammotropin hormone 1 chr17 GO:0031667 Not Cancer Driver No 33 0.152 23 2 0.087 0
CSH2 CSH2 P0DML3 Chorionic somatomammotropin hormone 2 chr17 GO:0031667 Not Cancer Driver No 53 0.244 23 3 0.13 0
CSHL1 CSHL1 Q14406 Chorionic somatomammotropin hormone-like 1 chr17 GO:0031667 Not Cancer Driver No 63 0.284 18 5 0.278 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0031667 Not Cancer Driver No 19 0.194 12 4 0.333 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0031667 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0031667 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP24A1 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial chr20 GO:0031667 Not Cancer Driver No 74 0.144 77 5 0.065 4
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0031667 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0031667 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0031667 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0031667 Not Cancer Driver No 91 0.182 5 1 0.2 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0031667 Not Cancer Driver No 48 0.142 53 6 0.113 1
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0031667 Census, Compendium Yes 194 0.213 371 59 0.159 16
EIF2A EIF2A Q9BY44 Eukaryotic translation initiation factor 2A chr3 GO:0031667 Not Cancer Driver No 51 0.087 162 19 0.117 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0031667 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0031667 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0031667 Not Cancer Driver No 156 0.095 494 44 0.089 2
EPO EPO P01588 Erythropoietin chr7 GO:0031667 Not Cancer Driver No 27 0.14 9 1 0.111 1
F5 F5 P12259 Coagulation factor V chr1 GO:0031667 Not Cancer Driver No 455 0.205 974 223 0.229 7
F7 F7 P08709 Coagulation factor VII chr13 GO:0031667 Not Cancer Driver No 74 0.159 50 7 0.14 108
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0031667 Census Yes 103 0.125 245 34 0.139 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0031667 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0031667 Not Cancer Driver No 84 0.335 97 51 0.526 7
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0031667 Not Cancer Driver No 10 0.093 58 4 0.069 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0031667 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0031667 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0031667 Compendium Yes 70 0.153 258 34 0.132 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0031667 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0031667 Census Yes 75 0.149 441 61 0.138 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0031667 Not Cancer Driver No 86 0.167 28 3 0.107 58
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0031667 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0031667 Not Cancer Driver No 19 0.162 10 1 0.1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0031667 Not Cancer Driver No 11 0.094 2 1 0.5 0
GALP GALP Q9UBC7 Galanin-like peptide chr19 GO:0031667 Not Cancer Driver No 35 0.302 41 15 0.366 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0031667 Not Cancer Driver No 82 0.121 42 6 0.143 0
GAST GAST P01350 Gastrin chr17 GO:0031667 Not Cancer Driver No 19 0.188 80 15 0.188 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0031667 Not Cancer Driver No 48 0.109 301 34 0.113 18
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0031667 Not Cancer Driver No 327 0.122 117 16 0.137 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0031667 Not Cancer Driver No 51 0.142 78 14 0.179 11
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0031667 Not Cancer Driver No 79 0.217 3 3 1.0 5
GH1 GH1 P01241 Somatotropin chr17 GO:0031667 Not Cancer Driver No 54 0.249 24 9 0.375 15
GH2_ENST00000423893 GH2 P01242 Growth hormone variant chr17 GO:0031667 Not Cancer Driver No 55 0.253 12 9 0.75 0
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0031667 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0031667 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0031667 Not Cancer Driver No 85 0.232 4 0 0.0 2
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0031667 Not Cancer Driver No 38 0.187 12 1 0.083 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0031667 Not Cancer Driver No 7 0.083 4 0 0.0 4
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0031667 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLCS HLCS P50747 Biotin--protein ligase chr21 GO:0031667 Not Cancer Driver No 95 0.131 158 15 0.095 23
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0031667 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0031667 Not Cancer Driver No 70 0.188 290 58 0.2 4
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0031667 Not Cancer Driver No 27 0.067 30 0 0.0 14
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0031667 Not Cancer Driver No 73 0.112 282 35 0.124 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0031667 Not Cancer Driver No 155 0.197 419 90 0.215 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0031667 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0031667 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0031667 Not Cancer Driver No 30 0.111 35 6 0.171 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0031667 Not Cancer Driver No 49 0.153 84 12 0.143 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0031667 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0031667 Not Cancer Driver No 166 0.141 26 0 0.0 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0031667 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0031667 Not Cancer Driver No 122 0.115 337 44 0.131 0
KL KL Q9UEF7 Klotho chr13 GO:0031667 Not Cancer Driver No 175 0.173 104 5 0.048 1
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:0031667 Not Cancer Driver No 44 0.101 21 2 0.095 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0031667 Not Cancer Driver No 103 0.222 20 5 0.25 1
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0031667 Not Cancer Driver No 133 0.113 97 10 0.103 1
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0031667 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEP LEP P41159 Leptin chr7 GO:0031667 Not Cancer Driver No 29 0.174 0 0 0.0 2
LPL LPL P06858 Lipoprotein lipase chr8 GO:0031667 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0031667 Not Cancer Driver No 54 0.235 2 0 0.0 1
LRCOL1 LRCOL1 A6NCL2 Leucine-rich colipase-like protein 1 chr12 GO:0031667 Not Cancer Driver No 1 0.006 0 0 0.0 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0031667 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0031667 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 GO:0031667 Not Cancer Driver No 10 0.08 17 1 0.059 0
MAP1LC3B2 MAP1LC3B2 A6NCE7 Microtubule-associated proteins 1A/1B light chain 3 beta 2 chr12 GO:0031667 Not Cancer Driver No 19 0.152 17 7 0.412 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 GO:0031667 Not Cancer Driver No 32 0.218 31 5 0.161 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0031667 Not Cancer Driver No 39 0.108 25 1 0.04 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0031667 Not Cancer Driver No 26 0.063 384 25 0.065 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:0031667 Not Cancer Driver No 50 0.172 246 46 0.187 0
MEAK7 MEAK7 Q6P9B6 MTOR-associated protein MEAK7 chr16 GO:0031667 Not Cancer Driver No 56 0.123 182 24 0.132 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0031667 Not Cancer Driver No 149 0.2 52 12 0.231 3
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 GO:0031667 Not Cancer Driver No 95 0.145 125 22 0.176 53
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0031667 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0031667 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0031667 Not Cancer Driver No 144 0.108 463 47 0.102 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0031667 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NDOR1_ENST00000344894 NDOR1 Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 chr9 GO:0031667 Not Cancer Driver No 60 0.101 67 7 0.104 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0031667 Census, Compendium Yes 228 0.377 402 62 0.154 4
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0031667 Not Cancer Driver No 73 0.167 126 21 0.167 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0031667 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0031667 Not Cancer Driver No 111 0.228 78 18 0.231 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0031667 Census, Compendium Yes 168 0.211 57 8 0.14 25
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0031667 Not Cancer Driver No 142 0.215 357 77 0.216 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0031667 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0031667 Not Cancer Driver No 107 0.268 58 27 0.466 0
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX GO:0031667 Not Cancer Driver No 89 0.251 24 4 0.167 111
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0031667 Not Cancer Driver No 10 0.08 0 0 0.0 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0031667 Not Cancer Driver No 62 0.149 296 48 0.162 23
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0031667 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0031667 Not Cancer Driver No 139 0.185 336 61 0.182 2
PCSK1N PCSK1N Q9UHG2 ProSAAS chrX GO:0031667 Not Cancer Driver No 7 0.027 187 7 0.037 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0031667 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0031667 Not Cancer Driver No 32 0.113 238 23 0.097 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0031667 Not Cancer Driver No 109 0.408 142 62 0.437 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0031667 Not Cancer Driver No 144 0.192 56 7 0.125 30
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0031667 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0031667 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0031667 Not Cancer Driver No 193 0.142 315 45 0.143 0
PLEC PLEC Q15149 Plectin chr8 GO:0031667 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0031667 Not Cancer Driver No 2 0.037 23 1 0.043 0
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 GO:0031667 Not Cancer Driver No 80 0.225 10 9 0.9 0
POSTN POSTN Q15063 Periostin chr13 GO:0031667 Not Cancer Driver No 204 0.244 86 27 0.314 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0031667 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0031667 Not Cancer Driver No 181 0.227 609 148 0.243 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0031667 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0031667 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0031667 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0031667 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0031667 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRL PRL P01236 Prolactin chr6 GO:0031667 Not Cancer Driver No 49 0.216 22 1 0.045 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0031667 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0031667 Not Cancer Driver No 44 0.196 21 6 0.286 3
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0031667 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0031667 Not Cancer Driver No 19 0.165 60 10 0.167 2
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0031667 Census, Compendium Yes 70 0.152 167 14 0.084 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0031667 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0031667 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0031667 Not Cancer Driver No 42 0.105 83 5 0.06 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0031667 Not Cancer Driver No 66 0.145 270 44 0.163 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0031667 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCT SCT P09683 Secretin chr11 GO:0031667 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:0031667 Not Cancer Driver No 74 0.168 18 1 0.056 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0031667 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0031667 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0031667 Not Cancer Driver No 84 0.171 44 4 0.091 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0031667 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGIP1 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 GO:0031667 Not Cancer Driver No 210 0.254 559 152 0.272 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0031667 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0031667 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0031667 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0031667 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0031667 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 GO:0031667 Not Cancer Driver No 41 0.132 55 7 0.127 0
SLC10A1 SLC10A1 Q14973 Sodium/bile acid cotransporter chr14 GO:0031667 Not Cancer Driver No 39 0.112 0 0 0.0 4
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 GO:0031667 Not Cancer Driver No 69 0.138 70 3 0.043 3
SLC25A25_ENST00000373064 SLC25A25 Q6KCM7 Calcium-binding mitochondrial carrier protein SCaMC-2 chr9 GO:0031667 Not Cancer Driver No 45 0.096 5 1 0.2 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0031667 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0031667 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0031667 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 GO:0031667 Not Cancer Driver No 77 0.119 116 11 0.095 9
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0031667 Not Cancer Driver No 67 0.124 139 18 0.129 1
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0031667 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0031667 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 GO:0031667 Not Cancer Driver No 29 0.081 41 7 0.171 3
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0031667 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPP1 SPP1 P10451 Osteopontin chr4 GO:0031667 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0031667 Census Yes 53 0.099 130 11 0.085 1
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0031667 Not Cancer Driver No 48 0.189 0 0 0.0 21
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0031667 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRF SRF P11831 Serum response factor chr6 GO:0031667 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 GO:0031667 Census, Compendium Yes 38 0.172 219 38 0.174 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0031667 Not Cancer Driver No 59 0.239 58 12 0.207 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0031667 Not Cancer Driver No 71 0.235 112 29 0.259 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0031667 Not Cancer Driver No 59 0.143 15 1 0.067 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0031667 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 GO:0031667 Census, Compendium Yes 82 0.16 136 19 0.14 4
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 GO:0031667 Not Cancer Driver No 68 0.152 115 13 0.113 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0031667 Not Cancer Driver No 61 0.116 149 21 0.141 38
TMEM135 TMEM135 Q86UB9 Transmembrane protein 135 chr11 GO:0031667 Not Cancer Driver No 62 0.135 14 3 0.214 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0031667 Not Cancer Driver No 24 0.103 45 3 0.067 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0031667 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0031667 Not Cancer Driver No 118 0.241 55 17 0.309 1
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0031667 Not Cancer Driver No 59 0.094 225 20 0.089 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0031667 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSHB_ENST00000369517 TSHB P01222 Thyrotropin subunit beta chr1 GO:0031667 Not Cancer Driver No 34 0.246 0 0 0.0 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0031667 Not Cancer Driver No 5 0.03 1 0 0.0 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0031667 Not Cancer Driver No 22 0.07 41 0 0.0 0
TYR TYR P14679 Tyrosinase chr11 GO:0031667 Not Cancer Driver No 156 0.295 52 15 0.288 111
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0031667 Not Cancer Driver No 43 0.14 1 0 0.0 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0031667 Not Cancer Driver No 47 0.152 13 3 0.231 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0031667 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0031667 Not Cancer Driver No 30 0.087 326 29 0.089 0
VGF VGF O15240 Neurosecretory protein VGF chr7 GO:0031667 Not Cancer Driver No 48 0.078 593 47 0.079 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0031667 Not Cancer Driver No 55 0.155 59 4 0.068 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0031667 Not Cancer Driver No 19 0.073 169 9 0.053 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 GO:0031667 Not Cancer Driver No 103 0.148 70 15 0.214 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0031667 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0031667 Census, Compendium Yes 246 0.219 831 200 0.241 8