Total number of protein in "GO:0030662" GO term: 95
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0030662 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0030662 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| AP1G1_ENST00000569748 | AP1G1 | O43747 | AP-1 complex subunit gamma-1 | chr16 | GO:0030662 | Not Cancer Driver | No | 111 | 0.135 | 144 | 22 | 0.153 | 0 |
| AP2A1 | AP2A1 | O95782 | AP-2 complex subunit alpha-1 | chr19 | GO:0030662 | Not Cancer Driver | No | 95 | 0.097 | 188 | 12 | 0.064 | 0 |
| AP2A2_ENST00000448903 | AP2A2 | O94973 | AP-2 complex subunit alpha-2 | chr11 | GO:0030662 | Not Cancer Driver | No | 100 | 0.106 | 145 | 12 | 0.083 | 0 |
| AP2B1_ENST00000621914 | AP2B1 | P63010 | AP-2 complex subunit beta | chr17 | GO:0030662 | Not Cancer Driver | No | 85 | 0.091 | 95 | 12 | 0.126 | 0 |
| AP2M1_ENST00000292807 | AP2M1 | Q96CW1 | AP-2 complex subunit mu | chr3 | GO:0030662 | Not Cancer Driver | No | 55 | 0.126 | 41 | 9 | 0.22 | 1 |
| AP2S1_ENST00000263270 | AP2S1 | P53680 | AP-2 complex subunit sigma | chr19 | GO:0030662 | Not Cancer Driver | No | 4 | 0.028 | 0 | 0 | 0.0 | 3 |
| AP3B1 | AP3B1 | O00203 | AP-3 complex subunit beta-1 | chr5 | GO:0030662 | Not Cancer Driver | No | 126 | 0.115 | 316 | 31 | 0.098 | 1 |
| AP3B2_ENST00000261722 | AP3B2 | Q13367 | AP-3 complex subunit beta-2 | chr15 | GO:0030662 | Not Cancer Driver | No | 145 | 0.134 | 381 | 51 | 0.134 | 0 |
| APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | GO:0030662 | Not Cancer Driver | No | 1022 | 0.224 | 315 | 72 | 0.229 | 3 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0030662 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| AREG | AREG | P15514 | Amphiregulin | chr4 | GO:0030662 | Not Cancer Driver | No | 28 | 0.111 | 149 | 20 | 0.134 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0030662 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| AVPR2_ENST00000337474 | AVPR2 | P30518 | Vasopressin V2 receptor | chrX | GO:0030662 | Not Cancer Driver | No | 58 | 0.156 | 56 | 7 | 0.125 | 84 |
| BTC | BTC | P35070 | Probetacellulin | chr4 | GO:0030662 | Not Cancer Driver | No | 29 | 0.163 | 12 | 5 | 0.417 | 0 |
| CD207 | CD207 | Q9UJ71 | C-type lectin domain family 4 member K | chr2 | GO:0030662 | Not Cancer Driver | No | 77 | 0.235 | 56 | 13 | 0.232 | 1 |
| CD3D | CD3D | P04234 | T-cell surface glycoprotein CD3 delta chain | chr11 | GO:0030662 | Not Cancer Driver | No | 23 | 0.135 | 2 | 1 | 0.5 | 0 |
| CD3G | CD3G | P09693 | T-cell surface glycoprotein CD3 gamma chain | chr11 | GO:0030662 | Not Cancer Driver | No | 25 | 0.137 | 48 | 7 | 0.146 | 0 |
| CD4 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0030662 | Not Cancer Driver | No | 69 | 0.151 | 56 | 11 | 0.196 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0030662 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CD9 | CD9 | P21926 | CD9 antigen | chr12 | GO:0030662 | Not Cancer Driver | No | 22 | 0.096 | 0 | 0 | 0.0 | 0 |
| CEMIP_ENST00000356249 | CEMIP | Q8WUJ3 | Cell migration-inducing and hyaluronan-binding protein | chr15 | GO:0030662 | Not Cancer Driver | No | 207 | 0.152 | 105 | 10 | 0.095 | 0 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | GO:0030662 | Not Cancer Driver | No | 287 | 0.194 | 145 | 18 | 0.124 | 151 |
| CHRM2_ENST00000320658 | CHRM2 | P08172 | Muscarinic acetylcholine receptor M2 | chr7 | GO:0030662 | Not Cancer Driver | No | 218 | 0.468 | 169 | 93 | 0.55 | 0 |
| CLTC_ENST00000269122 | CLTC | Q00610 | Clathrin heavy chain 1 | chr17 | GO:0030662 | Census, Compendium | Yes | 190 | 0.113 | 71 | 6 | 0.085 | 1 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0030662 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0030662 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DENND1A | DENND1A | Q8TEH3 | DENN domain-containing protein 1A | chr9 | GO:0030662 | Not Cancer Driver | No | 117 | 0.116 | 589 | 76 | 0.129 | 0 |
| DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | GO:0030662 | Not Cancer Driver | No | 23 | 0.116 | 46 | 6 | 0.13 | 1 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0030662 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0030662 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EPGN | EPGN | Q6UW88 | Epigen | chr4 | GO:0030662 | Not Cancer Driver | No | 16 | 0.104 | 0 | 0 | 0.0 | 0 |
| EREG | EREG | O14944 | Proepiregulin | chr4 | GO:0030662 | Not Cancer Driver | No | 26 | 0.154 | 10 | 3 | 0.3 | 0 |
| FCGR1A | FCGR1A | P12314 | High affinity immunoglobulin gamma Fc receptor I | chr1 | GO:0030662 | Not Cancer Driver | No | 62 | 0.166 | 37 | 5 | 0.135 | 0 |
| FCGR1B | FCGR1BP | Q92637 | Putative high affinity immunoglobulin gamma Fc receptor IB | chr1 | GO:0030662 | Not Cancer Driver | No | 31 | 0.111 | 37 | 6 | 0.162 | 0 |
| FZD2 | FZD2 | Q14332 | Frizzled-2 | chr17 | GO:0030662 | Not Cancer Driver | No | 85 | 0.15 | 47 | 5 | 0.106 | 1 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0030662 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0030662 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| GAD1 | GAD1 | Q99259 | Glutamate decarboxylase 1 | chr2 | GO:0030662 | Not Cancer Driver | No | 113 | 0.19 | 55 | 5 | 0.091 | 1 |
| GAD2_ENST00000259271 | GAD2 | Q05329 | Glutamate decarboxylase 2 | chr10 | GO:0030662 | Not Cancer Driver | No | 148 | 0.253 | 37 | 7 | 0.189 | 0 |
| HBEGF | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0030662 | Not Cancer Driver | No | 16 | 0.077 | 63 | 3 | 0.048 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0030662 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0030662 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| HLA-DPA1 | HLA-DPA1 | P20036 | HLA class II histocompatibility antigen, DP alpha 1 chain | chr6 | GO:0030662 | Not Cancer Driver | No | 37 | 0.142 | 30 | 4 | 0.133 | 0 |
| HLA-DPB1 | HLA-DPB1 | P04440 | HLA class II histocompatibility antigen, DP beta 1 chain | chr6 | GO:0030662 | Not Cancer Driver | No | 38 | 0.147 | 39 | 4 | 0.103 | 0 |
| HLA-DQA2 | HLA-DQA2 | P01906 | HLA class II histocompatibility antigen, DQ alpha 2 chain | chr6 | GO:0030662 | Not Cancer Driver | No | 61 | 0.239 | 7 | 0 | 0.0 | 0 |
| HLA-DQB2 | HLA-DQB2 | P05538 | HLA class II histocompatibility antigen, DQ beta 2 chain | chr6 | GO:0030662 | Not Cancer Driver | No | 55 | 0.205 | 38 | 5 | 0.132 | 0 |
| HLA-DRA | HLA-DRA | P01903 | HLA class II histocompatibility antigen, DR alpha chain | chr6 | GO:0030662 | Not Cancer Driver | No | 52 | 0.205 | 12 | 1 | 0.083 | 0 |
| HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0030662 | Not Cancer Driver | No | 48 | 0.18 | 12 | 1 | 0.083 | 0 |
| HLA-DRB5 | HLA-DRB5 | Q30154 | HLA class II histocompatibility antigen, DR beta 5 chain | chr6 | GO:0030662 | Not Cancer Driver | No | 35 | 0.132 | 18 | 2 | 0.111 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | GO:0030662 | Not Cancer Driver | No | 149 | 0.231 | 251 | 52 | 0.207 | 0 |
| IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0030662 | Not Cancer Driver | No | 318 | 0.128 | 255 | 20 | 0.078 | 0 |
| IL7R | IL7R | P16871 | Interleukin-7 receptor subunit alpha | chr5 | GO:0030662 | Census, Compendium | Yes | 177 | 0.386 | 88 | 48 | 0.545 | 1 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | GO:0030662 | Not Cancer Driver | No | 32 | 0.151 | 0 | 0 | 0.0 | 0 |
| KDELR2 | KDELR2 | P33947 | ER lumen protein-retaining receptor 2 | chr7 | GO:0030662 | Not Cancer Driver | No | 23 | 0.108 | 0 | 0 | 0.0 | 1 |
| KDELR3_ENST00000216014 | KDELR3 | O43731 | ER lumen protein-retaining receptor 3 | chr22 | GO:0030662 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
| KIAA0319_ENST00000543707 | KIAA0319 | Q5VV43 | Dyslexia-associated protein KIAA0319 | chr6 | GO:0030662 | Not Cancer Driver | No | 204 | 0.19 | 492 | 85 | 0.173 | 0 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0030662 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0030662 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0030662 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| M6PR | M6PR | P20645 | Cation-dependent mannose-6-phosphate receptor | chr12 | GO:0030662 | Not Cancer Driver | No | 16 | 0.058 | 35 | 4 | 0.114 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | GO:0030662 | Not Cancer Driver | No | 176 | 0.136 | 342 | 41 | 0.12 | 3 |
| NRGN | NRGN | Q92686 | Neurogranin | chr11 | GO:0030662 | Not Cancer Driver | No | 5 | 0.064 | 76 | 5 | 0.066 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | GO:0030662 | Not Cancer Driver | No | 25 | 0.124 | 25 | 2 | 0.08 | 0 |
| RAB3A | RAB3A | P20336 | Ras-related protein Rab-3A | chr19 | GO:0030662 | Not Cancer Driver | No | 25 | 0.114 | 43 | 4 | 0.093 | 0 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | GO:0030662 | Not Cancer Driver | No | 32 | 0.149 | 65 | 15 | 0.231 | 0 |
| RASSF9 | RASSF9 | O75901 | Ras association domain-containing protein 9 | chr12 | GO:0030662 | Not Cancer Driver | No | 88 | 0.202 | 131 | 24 | 0.183 | 0 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0030662 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| SCARB2 | SCARB2 | Q14108 | Lysosome membrane protein 2 | chr4 | GO:0030662 | Not Cancer Driver | No | 61 | 0.128 | 13 | 3 | 0.231 | 1 |
| SH3GL2 | SH3GL2 | Q99962 | Endophilin-A1 | chr9 | GO:0030662 | Not Cancer Driver | No | 76 | 0.216 | 214 | 50 | 0.234 | 0 |
| SLC17A7 | SLC17A7 | Q9P2U7 | Vesicular glutamate transporter 1 | chr19 | GO:0030662 | Not Cancer Driver | No | 79 | 0.141 | 80 | 21 | 0.263 | 0 |
| SLC18A1_ENST00000276373 | SLC18A1 | P54219 | Chromaffin granule amine transporter | chr8 | GO:0030662 | Not Cancer Driver | No | 98 | 0.187 | 28 | 4 | 0.143 | 0 |
| SLC18A2_ENST00000644641 | SLC18A2 | Q05940 | Synaptic vesicular amine transporter | chr10 | GO:0030662 | Not Cancer Driver | No | 105 | 0.204 | 23 | 7 | 0.304 | 1 |
| SLC18A3 | SLC18A3 | Q16572 | Vesicular acetylcholine transporter | chr10 | GO:0030662 | Not Cancer Driver | No | 125 | 0.235 | 90 | 23 | 0.256 | 2 |
| SLC2A8 | SLC2A8 | Q9NY64 | Solute carrier family 2, facilitated glucose transporter member 8 | chr9 | GO:0030662 | Not Cancer Driver | No | 28 | 0.059 | 19 | 0 | 0.0 | 0 |
| SLC32A1 | SLC32A1 | Q9H598 | Vesicular inhibitory amino acid transporter | chr20 | GO:0030662 | Not Cancer Driver | No | 138 | 0.263 | 82 | 19 | 0.232 | 0 |
| SYT11 | SYT11 | Q9BT88 | Synaptotagmin-11 | chr1 | GO:0030662 | Not Cancer Driver | No | 64 | 0.148 | 105 | 23 | 0.219 | 0 |
| SYT1_ENST00000393240 | SYT1 | P21579 | Synaptotagmin-1 | chr12 | GO:0030662 | Not Cancer Driver | No | 104 | 0.246 | 103 | 36 | 0.35 | 5 |
| SYT2_ENST00000367268 | SYT2 | Q8N9I0 | Synaptotagmin-2 | chr1 | GO:0030662 | Not Cancer Driver | No | 73 | 0.174 | 141 | 24 | 0.17 | 3 |
| SYT9 | SYT9 | Q86SS6 | Synaptotagmin-9 | chr11 | GO:0030662 | Not Cancer Driver | No | 120 | 0.244 | 148 | 42 | 0.284 | 0 |
| TEPSIN | TEPSIN | Q96N21 | AP-4 complex accessory subunit Tepsin | chr17 | GO:0030662 | Not Cancer Driver | No | 54 | 0.103 | 321 | 37 | 0.115 | 0 |
| TF | TF | P02787 | Serotransferrin | chr3 | GO:0030662 | Not Cancer Driver | No | 135 | 0.193 | 21 | 5 | 0.238 | 2 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0030662 | Census | Yes | 89 | 0.117 | 80 | 6 | 0.075 | 1 |
| TGFA_ENST00000295400 | TGFA | P01135 | Protransforming growth factor alpha | chr2 | GO:0030662 | Not Cancer Driver | No | 20 | 0.125 | 0 | 0 | 0.0 | 0 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | GO:0030662 | Not Cancer Driver | No | 51 | 0.117 | 399 | 46 | 0.115 | 0 |
| TMED2 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | GO:0030662 | Not Cancer Driver | No | 24 | 0.119 | 25 | 4 | 0.16 | 0 |
| TMEM199 | TMEM199 | Q8N511 | Transmembrane protein 199 | chr17 | GO:0030662 | Not Cancer Driver | No | 24 | 0.115 | 54 | 5 | 0.093 | 3 |
| TYRP1 | TYRP1 | P17643 | 5,6-dihydroxyindole-2-carboxylic acid oxidase | chr9 | GO:0030662 | Not Cancer Driver | No | 81 | 0.151 | 87 | 13 | 0.149 | 2 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0030662 | Not Cancer Driver | No | 7 | 0.06 | 47 | 4 | 0.085 | 3 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | GO:0030662 | Not Cancer Driver | No | 11 | 0.11 | 17 | 1 | 0.059 | 0 |
| VAMP4 | VAMP4 | O75379 | Vesicle-associated membrane protein 4 | chr1 | GO:0030662 | Not Cancer Driver | No | 9 | 0.064 | 80 | 6 | 0.075 | 0 |
| VAMP7_ENST00000286448 | VAMP7 | P51809 | Vesicle-associated membrane protein 7 | chrX | GO:0030662 | Not Cancer Driver | No | 38 | 0.173 | 4 | 1 | 0.25 | 0 |
| VAMP8 | VAMP8 | Q9BV40 | Vesicle-associated membrane protein 8 | chr2 | GO:0030662 | Not Cancer Driver | No | 9 | 0.09 | 27 | 0 | 0.0 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0030662 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |