Total number of protein in "GO:0010569" GO term: 52
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0010569 | Not Cancer Driver | No | 112 | 0.299 | 43 | 5 | 0.116 | 5 |
| ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:0010569 | Not Cancer Driver | No | 61 | 0.142 | 74 | 15 | 0.203 | 0 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:0010569 | Not Cancer Driver | No | 51 | 0.129 | 6 | 2 | 0.333 | 0 |
| ARID2 | ARID2 | Q68CP9 | AT-rich interactive domain-containing protein 2 | chr12 | GO:0010569 | Census, Compendium | Yes | 272 | 0.148 | 1143 | 141 | 0.123 | 0 |
| BRD8 | BRD8 | Q9H0E9 | Bromodomain-containing protein 8 | chr5 | GO:0010569 | Not Cancer Driver | No | 189 | 0.153 | 934 | 147 | 0.157 | 0 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0010569 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| DMAP1_ENST00000315913 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | GO:0010569 | Not Cancer Driver | No | 49 | 0.105 | 269 | 28 | 0.104 | 0 |
| EP400 | EP400 | Q96L91 | E1A-binding protein p400 | chr12 | GO:0010569 | Not Cancer Driver | No | 397 | 0.126 | 2064 | 234 | 0.113 | 0 |
| EPC1 | EPC1 | Q9H2F5 | Enhancer of polycomb homolog 1 | chr10 | GO:0010569 | Not Cancer Driver | No | 104 | 0.124 | 515 | 68 | 0.132 | 0 |
| EPC2 | EPC2 | Q52LR7 | Enhancer of polycomb homolog 2 | chr2 | GO:0010569 | Not Cancer Driver | No | 95 | 0.118 | 583 | 67 | 0.115 | 0 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0010569 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| FANCB | FANCB | Q8NB91 | Fanconi anemia group B protein | chrX | GO:0010569 | Not Cancer Driver | No | 109 | 0.127 | 24 | 5 | 0.208 | 0 |
| FIGNL1 | FIGNL1 | Q6PIW4 | Fidgetin-like protein 1 | chr7 | GO:0010569 | Not Cancer Driver | No | 75 | 0.111 | 224 | 23 | 0.103 | 0 |
| FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | GO:0010569 | Census | Yes | 51 | 0.097 | 524 | 51 | 0.097 | 20 |
| HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | GO:0010569 | Not Cancer Driver | No | 59 | 0.088 | 622 | 57 | 0.092 | 0 |
| ING3 | ING3 | Q9NXR8 | Inhibitor of growth protein 3 | chr7 | GO:0010569 | Not Cancer Driver | No | 44 | 0.105 | 292 | 32 | 0.11 | 1 |
| KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0010569 | Not Cancer Driver | No | 65 | 0.127 | 173 | 21 | 0.121 | 3 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0010569 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| KHDC3L | KHDC3L | Q587J8 | KH domain-containing protein 3 | chr6 | GO:0010569 | Not Cancer Driver | No | 68 | 0.313 | 121 | 43 | 0.355 | 0 |
| MBTD1_ENST00000415868 | MBTD1 | Q05BQ5 | MBT domain-containing protein 1 | chr17 | GO:0010569 | Not Cancer Driver | No | 66 | 0.105 | 119 | 8 | 0.067 | 0 |
| MEAF6_ENST00000296214 | MEAF6 | Q9HAF1 | Chromatin modification-related protein MEAF6 | chr1 | GO:0010569 | Not Cancer Driver | No | 22 | 0.115 | 171 | 21 | 0.123 | 0 |
| MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:0010569 | Not Cancer Driver | No | 73 | 0.071 | 11 | 0 | 0.0 | 0 |
| MORF4L1 | MORF4L1 | Q9UBU8 | Mortality factor 4-like protein 1 | chr15 | GO:0010569 | Not Cancer Driver | No | 43 | 0.119 | 163 | 17 | 0.104 | 0 |
| MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | GO:0010569 | Not Cancer Driver | No | 44 | 0.153 | 136 | 21 | 0.154 | 0 |
| MRGBP | MRGBP | Q9NV56 | MRG/MORF4L-binding protein | chr20 | GO:0010569 | Not Cancer Driver | No | 27 | 0.132 | 147 | 23 | 0.156 | 0 |
| MRNIP | MRNIP | Q6NTE8 | MRN complex-interacting protein | chr5 | GO:0010569 | Not Cancer Driver | No | 44 | 0.128 | 268 | 35 | 0.131 | 0 |
| OOEP | OOEP | A6NGQ2 | Oocyte-expressed protein homolog | chr6 | GO:0010569 | Not Cancer Driver | No | 46 | 0.309 | 48 | 14 | 0.292 | 0 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0010569 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
| POGZ | POGZ | Q7Z3K3 | Pogo transposable element with ZNF domain | chr1 | GO:0010569 | Not Cancer Driver | No | 157 | 0.111 | 746 | 78 | 0.105 | 0 |
| PPP4C_ENST00000561610 | PPP4C | P60510 | Serine/threonine-protein phosphatase 4 catalytic subunit | chr16 | GO:0010569 | Not Cancer Driver | No | 41 | 0.134 | 0 | 0 | 0.0 | 0 |
| PPP4R2 | PPP4R2 | Q9NY27 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 | chr3 | GO:0010569 | Not Cancer Driver | No | 32 | 0.077 | 314 | 26 | 0.083 | 0 |
| RAD51AP1 | RAD51AP1 | Q96B01 | RAD51-associated protein 1 | chr12 | GO:0010569 | Not Cancer Driver | No | 46 | 0.131 | 335 | 43 | 0.128 | 0 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0010569 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0010569 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0010569 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
| RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0010569 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0010569 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0010569 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
| SETD2 | SETD2 | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | chr3 | GO:0010569 | Census, Compendium | Yes | 321 | 0.125 | 1945 | 209 | 0.107 | 2 |
| SHLD2_ENST00000298784 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | GO:0010569 | Not Cancer Driver | No | 84 | 0.101 | 157 | 14 | 0.089 | 0 |
| SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0010569 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
| SPIDR | SPIDR | Q14159 | DNA repair-scaffolding protein | chr8 | GO:0010569 | Not Cancer Driver | No | 101 | 0.11 | 329 | 20 | 0.061 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0010569 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
| TEX15_ENST00000256246 | TEX15 | Q9BXT5 | Testis-expressed protein 15 | chr8 | GO:0010569 | Not Cancer Driver | No | 479 | 0.172 | 1258 | 223 | 0.177 | 0 |
| TIMELESS | TIMELESS | Q9UNS1 | Protein timeless homolog | chr12 | GO:0010569 | Not Cancer Driver | No | 154 | 0.127 | 367 | 51 | 0.139 | 0 |
| TRRAP | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | GO:0010569 | Census, Compendium | Yes | 554 | 0.144 | 402 | 59 | 0.147 | 8 |
| USP51 | USP51 | Q70EK9 | Ubiquitin carboxyl-terminal hydrolase 51 | chrX | GO:0010569 | Not Cancer Driver | No | 100 | 0.141 | 246 | 34 | 0.138 | 0 |
| VPS72 | VPS72 | Q15906 | Vacuolar protein sorting-associated protein 72 homolog | chr1 | GO:0010569 | Not Cancer Driver | No | 43 | 0.118 | 329 | 37 | 0.112 | 0 |
| WAS | WAS | P42768 | Wiskott-Aldrich syndrome protein | chrX | GO:0010569 | Census, Compendium | Yes | 75 | 0.149 | 400 | 55 | 0.138 | 30 |
| WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0010569 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
| WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0010569 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
| YEATS4 | YEATS4 | O95619 | YEATS domain-containing protein 4 | chr12 | GO:0010569 | Not Cancer Driver | No | 23 | 0.101 | 17 | 1 | 0.059 | 0 |