Total number of protein in "GO:0010389" GO term: 42
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0010389 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | GO:0010389 | Not Cancer Driver | No | 36 | 0.089 | 178 | 21 | 0.118 | 0 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:0010389 | Not Cancer Driver | No | 51 | 0.148 | 63 | 8 | 0.127 | 0 |
| BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | GO:0010389 | Census, Compendium | Yes | 193 | 0.142 | 1182 | 172 | 0.146 | 0 |
| CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:0010389 | Not Cancer Driver | No | 49 | 0.113 | 145 | 14 | 0.097 | 0 |
| CCNB3_ENST00000276014 | CCNB3 | Q8WWL7 | G2/mitotic-specific cyclin-B3 | chrX | GO:0010389 | Not Cancer Driver | No | 270 | 0.194 | 842 | 159 | 0.189 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0010389 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0010389 | Not Cancer Driver | No | 63 | 0.12 | 313 | 35 | 0.112 | 0 |
| CDC25B | CDC25B | P30305 | M-phase inducer phosphatase 2 | chr20 | GO:0010389 | Not Cancer Driver | No | 80 | 0.138 | 328 | 43 | 0.131 | 0 |
| CDC25C | CDC25C | P30307 | M-phase inducer phosphatase 3 | chr5 | GO:0010389 | Not Cancer Driver | No | 61 | 0.129 | 224 | 26 | 0.116 | 0 |
| CDC7 | CDC7 | O00311 | Cell division cycle 7-related protein kinase | chr1 | GO:0010389 | Not Cancer Driver | No | 72 | 0.125 | 185 | 24 | 0.13 | 0 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0010389 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0010389 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:0010389 | Census, Compendium | Yes | 52 | 0.172 | 52 | 5 | 0.096 | 3 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0010389 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CENPF | CENPF | P49454 | Centromere protein F | chr1 | GO:0010389 | Not Cancer Driver | No | 387 | 0.124 | 2136 | 260 | 0.122 | 0 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | GO:0010389 | Not Cancer Driver | No | 33 | 0.142 | 224 | 31 | 0.138 | 0 |
| CTC1 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0010389 | Not Cancer Driver | No | 142 | 0.117 | 103 | 8 | 0.078 | 9 |
| DBF4B | DBF4B | Q8NFT6 | Protein DBF4 homolog B | chr17 | GO:0010389 | Not Cancer Driver | No | 68 | 0.111 | 311 | 22 | 0.071 | 0 |
| DTL | DTL | Q9NZJ0 | Denticleless protein homolog | chr1 | GO:0010389 | Not Cancer Driver | No | 73 | 0.1 | 331 | 49 | 0.148 | 0 |
| FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | GO:0010389 | Not Cancer Driver | No | 48 | 0.107 | 113 | 13 | 0.115 | 0 |
| HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | GO:0010389 | Not Cancer Driver | No | 93 | 0.146 | 286 | 38 | 0.133 | 0 |
| KCNH5 | KCNH5 | Q8NCM2 | Potassium voltage-gated channel subfamily H member 5 | chr14 | GO:0010389 | Not Cancer Driver | No | 308 | 0.312 | 280 | 90 | 0.321 | 0 |
| KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | GO:0010389 | Not Cancer Driver | No | 222 | 0.135 | 774 | 102 | 0.132 | 2 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0010389 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MTA3 | MTA3 | Q9BTC8 | Metastasis-associated protein MTA3 | chr2 | GO:0010389 | Not Cancer Driver | No | 48 | 0.081 | 169 | 18 | 0.107 | 0 |
| PBX1 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0010389 | Census | Yes | 82 | 0.191 | 290 | 57 | 0.197 | 0 |
| PHOX2B | PHOX2B | Q99453 | Paired mesoderm homeobox protein 2B | chr4 | GO:0010389 | Census | Yes | 59 | 0.188 | 219 | 44 | 0.201 | 2 |
| PKIA | PKIA | P61925 | cAMP-dependent protein kinase inhibitor alpha | chr8 | GO:0010389 | Not Cancer Driver | No | 18 | 0.237 | 76 | 18 | 0.237 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | GO:0010389 | Not Cancer Driver | No | 31 | 0.144 | 43 | 4 | 0.093 | 0 |
| RAD51B_ENST00000487270 | RAD51B | O15315 | DNA repair protein RAD51 homolog 2 | chr14 | GO:0010389 | Census | Yes | 45 | 0.117 | 13 | 0 | 0.0 | 0 |
| RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | GO:0010389 | Not Cancer Driver | No | 47 | 0.125 | 18 | 2 | 0.111 | 6 |
| RCC2 | RCC2 | Q9P258 | Protein RCC2 | chr1 | GO:0010389 | Not Cancer Driver | No | 63 | 0.121 | 194 | 27 | 0.139 | 0 |
| RNASEH2B | RNASEH2B | Q5TBB1 | Ribonuclease H2 subunit B | chr13 | GO:0010389 | Not Cancer Driver | No | 34 | 0.109 | 84 | 9 | 0.107 | 14 |
| RRM1 | RRM1 | P23921 | Ribonucleoside-diphosphate reductase large subunit | chr11 | GO:0010389 | Not Cancer Driver | No | 74 | 0.093 | 41 | 7 | 0.171 | 0 |
| RRM2B | RRM2B | Q7LG56 | Ribonucleoside-diphosphate reductase subunit M2 B | chr8 | GO:0010389 | Not Cancer Driver | No | 46 | 0.131 | 32 | 5 | 0.156 | 9 |
| SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0010389 | Compendium | Yes | 172 | 0.135 | 617 | 73 | 0.118 | 0 |
| STOX1_ENST00000399169 | STOX1 | Q6ZVD7 | Storkhead-box protein 1 | chr10 | GO:0010389 | Not Cancer Driver | No | 121 | 0.122 | 659 | 83 | 0.126 | 2 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | GO:0010389 | Not Cancer Driver | No | 48 | 0.11 | 167 | 17 | 0.102 | 4 |
| VPS4B | VPS4B | O75351 | Vacuolar protein sorting-associated protein 4B | chr18 | GO:0010389 | Not Cancer Driver | No | 52 | 0.117 | 195 | 22 | 0.113 | 0 |
| WNT10B | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0010389 | Not Cancer Driver | No | 56 | 0.144 | 84 | 16 | 0.19 | 2 |
| ZFYVE19 | ZFYVE19 | Q96K21 | Abscission/NoCut checkpoint regulator | chr15 | GO:0010389 | Not Cancer Driver | No | 41 | 0.087 | 361 | 28 | 0.078 | 0 |