Total number of protein in "GO:0009123" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0009123 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| ADK | ADK | P55263 | Adenosine kinase | chr10 | GO:0009123 | Not Cancer Driver | No | 29 | 0.08 | 33 | 2 | 0.061 | 3 |
| ADSL | ADSL | P30566 | Adenylosuccinate lyase | chr22 | GO:0009123 | Not Cancer Driver | No | 68 | 0.14 | 36 | 9 | 0.25 | 27 |
| ADSS | ADSS2 | P30520 | Adenylosuccinate synthetase isozyme 2 | chr1 | GO:0009123 | Not Cancer Driver | No | 49 | 0.107 | 48 | 4 | 0.083 | 0 |
| ADSSL1_ENST00000330877 | ADSS1 | Q8N142 | Adenylosuccinate synthetase isozyme 1 | chr14 | GO:0009123 | Not Cancer Driver | No | 74 | 0.162 | 68 | 6 | 0.088 | 1 |
| AK1_ENST00000373176 | AK1 | P00568 | Adenylate kinase isoenzyme 1 | chr9 | GO:0009123 | Not Cancer Driver | No | 19 | 0.098 | 55 | 3 | 0.055 | 4 |
| AK2 | AK2 | P54819 | Adenylate kinase 2, mitochondrial | chr1 | GO:0009123 | Not Cancer Driver | No | 23 | 0.096 | 76 | 12 | 0.158 | 2 |
| AK4 | AK4 | P27144 | Adenylate kinase 4, mitochondrial | chr1 | GO:0009123 | Not Cancer Driver | No | 26 | 0.117 | 24 | 3 | 0.125 | 0 |
| AK5 | AK5 | Q9Y6K8 | Adenylate kinase isoenzyme 5 | chr1 | GO:0009123 | Not Cancer Driver | No | 116 | 0.206 | 161 | 44 | 0.273 | 0 |
| AK6 | AK6 | Q9Y3D8 | Adenylate kinase isoenzyme 6 | chr5 | GO:0009123 | Not Cancer Driver | No | 6 | 0.035 | 13 | 0 | 0.0 | 0 |
| AK7 | AK7 | Q96M32 | Adenylate kinase 7 | chr14 | GO:0009123 | Not Cancer Driver | No | 126 | 0.174 | 181 | 42 | 0.232 | 1 |
| AK8 | AK8 | Q96MA6 | Adenylate kinase 8 | chr9 | GO:0009123 | Not Cancer Driver | No | 74 | 0.154 | 53 | 8 | 0.151 | 0 |
| AK9 | AK9 | Q5TCS8 | Adenylate kinase 9 | chr6 | GO:0009123 | Not Cancer Driver | No | 235 | 0.123 | 589 | 58 | 0.098 | 0 |
| AMPD1 | AMPD1 | P23109 | AMP deaminase 1 | chr1 | GO:0009123 | Not Cancer Driver | No | 218 | 0.292 | 112 | 25 | 0.223 | 2 |
| AMPD2_ENST00000528667 | AMPD2 | Q01433 | AMP deaminase 2 | chr1 | GO:0009123 | Not Cancer Driver | No | 93 | 0.106 | 275 | 27 | 0.098 | 3 |
| AMPD3_ENST00000529507 | AMPD3 | Q01432 | AMP deaminase 3 | chr11 | GO:0009123 | Not Cancer Driver | No | 132 | 0.172 | 207 | 38 | 0.184 | 10 |
| APRT | APRT | P07741 | Adenine phosphoribosyltransferase | chr16 | GO:0009123 | Not Cancer Driver | No | 16 | 0.089 | 0 | 0 | 0.0 | 8 |
| ATIC | ATIC | P31939 | Bifunctional purine biosynthesis protein ATIC | chr2 | GO:0009123 | Census | Yes | 74 | 0.125 | 25 | 1 | 0.04 | 1 |
| CAD | CAD | P27708 | CAD protein | chr2 | GO:0009123 | Not Cancer Driver | No | 287 | 0.129 | 368 | 52 | 0.141 | 1 |
| CARD11 | CARD11 | Q9BXL7 | Caspase recruitment domain-containing protein 11 | chr7 | GO:0009123 | Census, Compendium | Yes | 303 | 0.263 | 530 | 140 | 0.264 | 5 |
| CASK_ENST00000378163 | CASK | O14936 | Peripheral plasma membrane protein CASK | chrX | GO:0009123 | Not Cancer Driver | No | 118 | 0.127 | 285 | 45 | 0.158 | 4 |
| CDA | CDA | P32320 | Cytidine deaminase | chr1 | GO:0009123 | Not Cancer Driver | No | 21 | 0.144 | 8 | 0 | 0.0 | 0 |
| CMPK2 | CMPK2 | Q5EBM0 | UMP-CMP kinase 2, mitochondrial | chr2 | GO:0009123 | Not Cancer Driver | No | 41 | 0.091 | 99 | 8 | 0.081 | 0 |
| DCK | DCK | P27707 | Deoxycytidine kinase | chr4 | GO:0009123 | Not Cancer Driver | No | 29 | 0.112 | 22 | 4 | 0.182 | 0 |
| DCTD_ENST00000438320 | DCTD | P32321 | Deoxycytidylate deaminase | chr4 | GO:0009123 | Not Cancer Driver | No | 33 | 0.185 | 3 | 0 | 0.0 | 0 |
| DGUOK | DGUOK | Q16854 | Deoxyguanosine kinase, mitochondrial | chr2 | GO:0009123 | Not Cancer Driver | No | 25 | 0.09 | 17 | 1 | 0.059 | 6 |
| DHODH | DHODH | Q02127 | Dihydroorotate dehydrogenase (quinone), mitochondrial | chr16 | GO:0009123 | Not Cancer Driver | No | 44 | 0.111 | 96 | 11 | 0.115 | 10 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0009123 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DLG2_ENST00000398309 | DLG2 | Q15700 | Disks large homolog 2 | chr11 | GO:0009123 | Not Cancer Driver | No | 224 | 0.257 | 303 | 107 | 0.353 | 0 |
| DNPH1 | DNPH1 | O43598 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | chr6 | GO:0009123 | Not Cancer Driver | No | 15 | 0.086 | 49 | 3 | 0.061 | 0 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0009123 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| DPYS | DPYS | Q14117 | Dihydropyrimidinase | chr8 | GO:0009123 | Not Cancer Driver | No | 148 | 0.285 | 103 | 28 | 0.272 | 5 |
| DTYMK | DTYMK | P23919 | Thymidylate kinase | chr2 | GO:0009123 | Not Cancer Driver | No | 10 | 0.047 | 0 | 0 | 0.0 | 0 |
| DUT | DUT | P33316 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | chr15 | GO:0009123 | Not Cancer Driver | No | 19 | 0.075 | 128 | 8 | 0.062 | 0 |
| ENTPD8 | ENTPD8 | Q5MY95 | Ectonucleoside triphosphate diphosphohydrolase 8 | chr9 | GO:0009123 | Not Cancer Driver | No | 46 | 0.093 | 5 | 0 | 0.0 | 0 |
| GART_ENST00000381815 | GART | P22102 | Trifunctional purine biosynthetic protein adenosine-3 | chr21 | GO:0009123 | Not Cancer Driver | No | 96 | 0.095 | 50 | 6 | 0.12 | 0 |
| GDA_ENST00000358399 | GDA | Q9Y2T3 | Guanine deaminase | chr9 | GO:0009123 | Not Cancer Driver | No | 86 | 0.189 | 22 | 7 | 0.318 | 0 |
| GMPR2_ENST00000399440 | GMPR2 | Q9P2T1 | GMP reductase 2 | chr14 | GO:0009123 | Not Cancer Driver | No | 30 | 0.086 | 9 | 1 | 0.111 | 0 |
| GMPS | GMPS | P49915 | GMP synthase [glutamine-hydrolyzing] | chr3 | GO:0009123 | Census, Compendium | Yes | 88 | 0.127 | 76 | 10 | 0.132 | 0 |
| GUK1_ENST00000366718 | GUK1 | Q16774 | Guanylate kinase | chr1 | GO:0009123 | Not Cancer Driver | No | 28 | 0.142 | 71 | 9 | 0.127 | 0 |
| HPRT1 | HPRT1 | P00492 | Hypoxanthine-guanine phosphoribosyltransferase | chrX | GO:0009123 | Not Cancer Driver | No | 22 | 0.101 | 3 | 0 | 0.0 | 62 |
| IMPDH1_ENST00000626419 | IMPDH1 | P20839 | Inosine-5'-monophosphate dehydrogenase 1 | chr7 | GO:0009123 | Not Cancer Driver | No | 75 | 0.146 | 13 | 1 | 0.077 | 7 |
| IMPDH2 | IMPDH2 | P12268 | Inosine-5'-monophosphate dehydrogenase 2 | chr3 | GO:0009123 | Not Cancer Driver | No | 70 | 0.136 | 6 | 1 | 0.167 | 0 |
| LRGUK | LRGUK | Q96M69 | Leucine-rich repeat and guanylate kinase domain-containing protein | chr7 | GO:0009123 | Not Cancer Driver | No | 145 | 0.176 | 204 | 37 | 0.181 | 0 |
| MAGI3 | MAGI3 | Q5TCQ9 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 | chr1 | GO:0009123 | Not Cancer Driver | No | 154 | 0.104 | 1039 | 105 | 0.101 | 0 |
| MPP1 | MPP1 | Q00013 | 55 kDa erythrocyte membrane protein | chrX | GO:0009123 | Not Cancer Driver | No | 79 | 0.17 | 194 | 33 | 0.17 | 0 |
| NT5C | NT5C | Q8TCD5 | 5'(3')-deoxyribonucleotidase, cytosolic type | chr17 | GO:0009123 | Not Cancer Driver | No | 19 | 0.095 | 4 | 0 | 0.0 | 0 |
| NT5C1A | NT5C1A | Q9BXI3 | Cytosolic 5'-nucleotidase 1A | chr1 | GO:0009123 | Not Cancer Driver | No | 86 | 0.234 | 95 | 16 | 0.168 | 0 |
| NT5C2_ENST00000404739 | NT5C2 | P49902 | Cytosolic purine 5'-nucleotidase | chr10 | GO:0009123 | Census | Yes | 57 | 0.102 | 85 | 8 | 0.094 | 0 |
| NT5E | NT5E | P21589 | 5'-nucleotidase | chr6 | GO:0009123 | Not Cancer Driver | No | 61 | 0.106 | 26 | 2 | 0.077 | 1 |
| NT5M | NT5M | Q9NPB1 | 5'(3')-deoxyribonucleotidase, mitochondrial | chr17 | GO:0009123 | Not Cancer Driver | No | 20 | 0.088 | 0 | 0 | 0.0 | 0 |
| NUDT2_ENST00000346365 | NUDT2 | P50583 | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | chr9 | GO:0009123 | Not Cancer Driver | No | 16 | 0.109 | 24 | 1 | 0.042 | 0 |
| PAICS_ENST00000512576 | PAICS | P22234 | Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase | chr4 | GO:0009123 | Not Cancer Driver | No | 23 | 0.054 | 35 | 3 | 0.086 | 0 |
| PFAS | PFAS | O15067 | Phosphoribosylformylglycinamidine synthase | chr17 | GO:0009123 | Not Cancer Driver | No | 157 | 0.117 | 380 | 36 | 0.095 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | GO:0009123 | Not Cancer Driver | No | 38 | 0.131 | 29 | 2 | 0.069 | 5 |
| PPAT | PPAT | Q06203 | Amidophosphoribosyltransferase | chr4 | GO:0009123 | Not Cancer Driver | No | 66 | 0.128 | 48 | 4 | 0.083 | 0 |
| PRPS1 | PRPS1 | P60891 | Ribose-phosphate pyrophosphokinase 1 | chrX | GO:0009123 | Not Cancer Driver | No | 50 | 0.157 | 0 | 0 | 0.0 | 14 |
| PRPS1L1_ENST00000638645 | PRPS1L1 | P21108 | Ribose-phosphate pyrophosphokinase 3 | chr7 | GO:0009123 | Not Cancer Driver | No | 83 | 0.261 | 0 | 0 | 0.0 | 0 |
| PRPS2_ENST00000380668 | PRPS2 | P11908 | Ribose-phosphate pyrophosphokinase 2 | chrX | GO:0009123 | Not Cancer Driver | No | 56 | 0.176 | 4 | 1 | 0.25 | 0 |
| PRTFDC1 | PRTFDC1 | Q9NRG1 | Phosphoribosyltransferase domain-containing protein 1 | chr10 | GO:0009123 | Not Cancer Driver | No | 29 | 0.129 | 3 | 0 | 0.0 | 0 |
| RFK | RFK | Q969G6 | Riboflavin kinase | chr9 | GO:0009123 | Not Cancer Driver | No | 15 | 0.097 | 1 | 0 | 0.0 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | GO:0009123 | Not Cancer Driver | No | 51 | 0.106 | 32 | 7 | 0.219 | 0 |
| TJP2_ENST00000377245 | TJP2 | Q9UDY2 | Tight junction protein ZO-2 | chr9 | GO:0009123 | Not Cancer Driver | No | 149 | 0.125 | 919 | 113 | 0.123 | 1 |
| TK1 | TK1 | P04183 | Thymidine kinase, cytosolic | chr17 | GO:0009123 | Not Cancer Driver | No | 26 | 0.111 | 13 | 4 | 0.308 | 0 |
| TK2 | TK2 | O00142 | Thymidine kinase 2, mitochondrial | chr16 | GO:0009123 | Not Cancer Driver | No | 23 | 0.087 | 44 | 3 | 0.068 | 11 |
| TYMP_ENST00000395680 | TYMP | P19971 | Thymidine phosphorylase | chr22 | GO:0009123 | Not Cancer Driver | No | 28 | 0.058 | 143 | 7 | 0.049 | 5 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0009123 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| UCK1_ENST00000372215 | UCK1 | Q9HA47 | Uridine-cytidine kinase 1 | chr9 | GO:0009123 | Not Cancer Driver | No | 35 | 0.126 | 70 | 3 | 0.043 | 0 |
| UCK2 | UCK2 | Q9BZX2 | Uridine-cytidine kinase 2 | chr1 | GO:0009123 | Not Cancer Driver | No | 43 | 0.165 | 61 | 10 | 0.164 | 0 |
| UCKL1 | UCKL1 | Q9NWZ5 | Uridine-cytidine kinase-like 1 | chr20 | GO:0009123 | Not Cancer Driver | No | 54 | 0.099 | 134 | 15 | 0.112 | 0 |
| UMPS | UMPS | P11172 | Uridine 5'-monophosphate synthase | chr3 | GO:0009123 | Not Cancer Driver | No | 58 | 0.121 | 18 | 2 | 0.111 | 3 |
| UPB1 | UPB1 | Q9UBR1 | Beta-ureidopropionase | chr22 | GO:0009123 | Not Cancer Driver | No | 66 | 0.172 | 22 | 7 | 0.318 | 8 |
| UPP1_ENST00000395564 | UPP1 | Q16831 | Uridine phosphorylase 1 | chr7 | GO:0009123 | Not Cancer Driver | No | 47 | 0.152 | 13 | 3 | 0.231 | 0 |
| UPP2_ENST00000005756 | UPP2 | O95045 | Uridine phosphorylase 2 | chr2 | GO:0009123 | Not Cancer Driver | No | 55 | 0.174 | 5 | 1 | 0.2 | 0 |
| UPRT | UPRT | Q96BW1 | Uracil phosphoribosyltransferase homolog | chrX | GO:0009123 | Not Cancer Driver | No | 64 | 0.207 | 76 | 15 | 0.197 | 0 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0009123 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |