Total number of protein in "GO:0008584" GO term: 95
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0008584 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ADAM15 | ADAM15 | Q13444 | Disintegrin and metalloproteinase domain-containing protein 15 | chr1 | GO:0008584 | Not Cancer Driver | No | 104 | 0.121 | 213 | 29 | 0.136 | 0 |
| ADAM21 | ADAM21 | Q9UKJ8 | Disintegrin and metalloproteinase domain-containing protein 21 | chr14 | GO:0008584 | Not Cancer Driver | No | 167 | 0.231 | 4 | 1 | 0.25 | 0 |
| ADAM29_ENST00000404450 | ADAM29 | Q9UKF5 | Disintegrin and metalloproteinase domain-containing protein 29 | chr4 | GO:0008584 | Not Cancer Driver | No | 257 | 0.313 | 124 | 39 | 0.315 | 0 |
| AGO4 | AGO4 | Q9HCK5 | Protein argonaute-4 | chr1 | GO:0008584 | Not Cancer Driver | No | 100 | 0.116 | 183 | 24 | 0.131 | 0 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0008584 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| AMHR2 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:0008584 | Not Cancer Driver | No | 77 | 0.134 | 117 | 7 | 0.06 | 8 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0008584 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| ARID5B | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0008584 | Not Cancer Driver | No | 162 | 0.136 | 769 | 95 | 0.124 | 0 |
| ASPM | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0008584 | Not Cancer Driver | No | 554 | 0.159 | 424 | 67 | 0.158 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0008584 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0008584 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0008584 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BIK | BIK | Q13323 | Bcl-2-interacting killer | chr22 | GO:0008584 | Not Cancer Driver | No | 16 | 0.1 | 21 | 4 | 0.19 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0008584 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0008584 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| CITED2_ENST00000367651 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0008584 | Not Cancer Driver | No | 23 | 0.085 | 230 | 18 | 0.078 | 0 |
| COL9A3 | COL9A3 | Q14050 | Collagen alpha-3(IX) chain | chr20 | GO:0008584 | Not Cancer Driver | No | 118 | 0.173 | 684 | 118 | 0.173 | 1 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0008584 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| CSDE1_ENST00000358528 | CSDE1 | O75534 | Cold shock domain-containing protein E1 | chr1 | GO:0008584 | Not Cancer Driver | No | 118 | 0.148 | 204 | 29 | 0.142 | 0 |
| CSMD1 | CSMD1 | Q96PZ7 | CUB and sushi domain-containing protein 1 | chr8 | GO:0008584 | Not Cancer Driver | No | 1236 | 0.347 | 234 | 76 | 0.325 | 0 |
| CTNNA1 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | GO:0008584 | Census | Yes | 126 | 0.139 | 268 | 35 | 0.131 | 4 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0008584 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| EIF2S2 | EIF2S2 | P20042 | Eukaryotic translation initiation factor 2 subunit 2 | chr20 | GO:0008584 | Not Cancer Driver | No | 37 | 0.111 | 185 | 12 | 0.065 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0008584 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0008584 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
| FANCA | FANCA | O15360 | Fanconi anemia group A protein | chr16 | GO:0008584 | Census, Compendium | Yes | 160 | 0.11 | 154 | 15 | 0.097 | 27 |
| FGF9 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0008584 | Not Cancer Driver | No | 41 | 0.197 | 43 | 10 | 0.233 | 1 |
| FSHR | FSHR | P23945 | Follicle-stimulating hormone receptor | chr2 | GO:0008584 | Not Cancer Driver | No | 226 | 0.325 | 28 | 11 | 0.393 | 16 |
| GATA1 | GATA1 | P15976 | Erythroid transcription factor | chrX | GO:0008584 | Census, Compendium | Yes | 68 | 0.165 | 242 | 41 | 0.169 | 5 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0008584 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0008584 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0008584 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
| GFRA1 | GFRA1 | P56159 | GDNF family receptor alpha-1 | chr10 | GO:0008584 | Not Cancer Driver | No | 120 | 0.258 | 43 | 12 | 0.279 | 0 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0008584 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0008584 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0008584 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0008584 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| HOXA10 | HOXA10 | P31260 | Homeobox protein Hox-A10 | chr7 | GO:0008584 | Not Cancer Driver | No | 35 | 0.085 | 339 | 25 | 0.074 | 0 |
| HOXA11 | HOXA11 | P31270 | Homeobox protein Hox-A11 | chr7 | GO:0008584 | Census, Compendium | Yes | 37 | 0.118 | 205 | 26 | 0.127 | 0 |
| INHA | INHA | P05111 | Inhibin alpha chain | chr2 | GO:0008584 | Not Cancer Driver | No | 48 | 0.131 | 144 | 15 | 0.104 | 0 |
| INHBA_ENST00000442711 | INHBA | P08476 | Inhibin beta A chain | chr7 | GO:0008584 | Not Cancer Driver | No | 148 | 0.347 | 154 | 63 | 0.409 | 0 |
| INSL3_ENST00000317306 | INSL3 | P51460 | Insulin-like 3 | chr19 | GO:0008584 | Not Cancer Driver | No | 18 | 0.137 | 34 | 12 | 0.353 | 3 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0008584 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0008584 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| KITLG | KITLG | P21583 | Kit ligand | chr12 | GO:0008584 | Not Cancer Driver | No | 48 | 0.176 | 61 | 9 | 0.148 | 1 |
| KLHL10 | KLHL10 | Q6JEL2 | Kelch-like protein 10 | chr17 | GO:0008584 | Not Cancer Driver | No | 77 | 0.127 | 24 | 2 | 0.083 | 2 |
| LHB | LHB | P01229 | Lutropin subunit beta | chr19 | GO:0008584 | Not Cancer Driver | No | 20 | 0.142 | 0 | 0 | 0.0 | 1 |
| LHCGR | LHCGR | P22888 | Lutropin-choriogonadotropic hormone receptor | chr2 | GO:0008584 | Not Cancer Driver | No | 181 | 0.259 | 12 | 8 | 0.667 | 25 |
| LHX9 | LHX9 | Q9NQ69 | LIM/homeobox protein Lhx9 | chr1 | GO:0008584 | Not Cancer Driver | No | 97 | 0.244 | 191 | 46 | 0.241 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0008584 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| LRRC6 | DNAAF11 | Q86X45 | Dynein axonemal assembly factor 11 | chr8 | GO:0008584 | Not Cancer Driver | No | 97 | 0.208 | 234 | 51 | 0.218 | 2 |
| MAMLD1_ENST00000262858 | MAMLD1 | Q13495 | Mastermind-like domain-containing protein 1 | chrX | GO:0008584 | Not Cancer Driver | No | 136 | 0.176 | 741 | 126 | 0.17 | 0 |
| MAS1 | MAS1 | P04201 | Proto-oncogene Mas | chr6 | GO:0008584 | Not Cancer Driver | No | 47 | 0.145 | 5 | 2 | 0.4 | 0 |
| MEA1 | MEA1 | Q16626 | Male-enhanced antigen 1 | chr6 | GO:0008584 | Not Cancer Driver | No | 12 | 0.065 | 185 | 12 | 0.065 | 0 |
| MMP14 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0008584 | Not Cancer Driver | No | 64 | 0.11 | 118 | 11 | 0.093 | 1 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0008584 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| NASP | NASP | P49321 | Nuclear autoantigenic sperm protein | chr1 | GO:0008584 | Not Cancer Driver | No | 95 | 0.121 | 615 | 81 | 0.132 | 0 |
| NHLH2_ENST00000320238 | NHLH2 | Q02577 | Helix-loop-helix protein 2 | chr1 | GO:0008584 | Not Cancer Driver | No | 19 | 0.141 | 83 | 8 | 0.096 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0008584 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NR0B1 | NR0B1 | P51843 | Nuclear receptor subfamily 0 group B member 1 | chrX | GO:0008584 | Not Cancer Driver | No | 106 | 0.226 | 97 | 18 | 0.186 | 18 |
| NR5A1 | NR5A1 | Q13285 | Steroidogenic factor 1 | chr9 | GO:0008584 | Not Cancer Driver | No | 60 | 0.13 | 133 | 29 | 0.218 | 24 |
| NUDT1_ENST00000397046 | NUDT1 | P36639 | Oxidized purine nucleoside triphosphate hydrolase | chr7 | GO:0008584 | Not Cancer Driver | No | 25 | 0.16 | 17 | 4 | 0.235 | 0 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0008584 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| PATZ1 | PATZ1 | Q9HBE1 | POZ-, AT hook-, and zinc finger-containing protein 1 | chr22 | GO:0008584 | Census | Yes | 91 | 0.132 | 301 | 38 | 0.126 | 0 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0008584 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0008584 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PRDX4 | PRDX4 | Q13162 | Peroxiredoxin-4 | chrX | GO:0008584 | Not Cancer Driver | No | 36 | 0.133 | 29 | 2 | 0.069 | 0 |
| PRKACG | PRKACG | P22612 | cAMP-dependent protein kinase catalytic subunit gamma | chr9 | GO:0008584 | Not Cancer Driver | No | 74 | 0.211 | 23 | 7 | 0.304 | 1 |
| PRPS1L1_ENST00000638645 | PRPS1L1 | P21108 | Ribose-phosphate pyrophosphokinase 3 | chr7 | GO:0008584 | Not Cancer Driver | No | 83 | 0.261 | 0 | 0 | 0.0 | 0 |
| REN | REN | P00797 | Renin | chr1 | GO:0008584 | Not Cancer Driver | No | 60 | 0.148 | 10 | 0 | 0.0 | 3 |
| RHOBTB3 | RHOBTB3 | O94955 | Rho-related BTB domain-containing protein 3 | chr5 | GO:0008584 | Not Cancer Driver | No | 67 | 0.11 | 34 | 2 | 0.059 | 0 |
| RNF38 | RNF38 | Q9H0F5 | E3 ubiquitin-protein ligase RNF38 | chr9 | GO:0008584 | Not Cancer Driver | No | 70 | 0.136 | 348 | 47 | 0.135 | 0 |
| RXFP2 | RXFP2 | Q8WXD0 | Relaxin receptor 2 | chr13 | GO:0008584 | Not Cancer Driver | No | 137 | 0.182 | 0 | 0 | 0.0 | 1 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0008584 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0008584 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SIX4 | SIX4 | Q9UIU6 | Homeobox protein SIX4 | chr14 | GO:0008584 | Not Cancer Driver | No | 99 | 0.127 | 460 | 58 | 0.126 | 0 |
| SOX15_ENST00000538513 | SOX15 | O60248 | Protein SOX-15 | chr17 | GO:0008584 | Not Cancer Driver | No | 18 | 0.077 | 227 | 18 | 0.079 | 0 |
| SOX8 | SOX8 | P57073 | Transcription factor SOX-8 | chr16 | GO:0008584 | Not Cancer Driver | No | 43 | 0.096 | 403 | 39 | 0.097 | 0 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0008584 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0008584 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SRD5A2 | SRD5A2 | P31213 | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | chr2 | GO:0008584 | Not Cancer Driver | No | 48 | 0.189 | 0 | 0 | 0.0 | 21 |
| TEX11_ENST00000344304 | TEX11 | Q8IYF3 | Testis-expressed protein 11 | chrX | GO:0008584 | Not Cancer Driver | No | 139 | 0.148 | 30 | 3 | 0.1 | 2 |
| TEX19 | TEX19 | Q8NA77 | Testis-expressed protein 19 | chr17 | GO:0008584 | Not Cancer Driver | No | 26 | 0.159 | 93 | 14 | 0.151 | 0 |
| TFAP2C | TFAP2C | Q92754 | Transcription factor AP-2 gamma | chr20 | GO:0008584 | Not Cancer Driver | No | 76 | 0.169 | 282 | 41 | 0.145 | 0 |
| TFPT | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | GO:0008584 | Census | Yes | 41 | 0.162 | 237 | 41 | 0.173 | 0 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0008584 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0008584 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
| TLR3 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0008584 | Not Cancer Driver | No | 123 | 0.136 | 0 | 0 | 0.0 | 1 |
| UTF1 | UTF1 | Q5T230 | Undifferentiated embryonic cell transcription factor 1 | chr10 | GO:0008584 | Not Cancer Driver | No | 4 | 0.012 | 316 | 3 | 0.009 | 0 |
| WNT2B | WNT2B | Q93097 | Protein Wnt-2b | chr1 | GO:0008584 | Not Cancer Driver | No | 72 | 0.184 | 27 | 3 | 0.111 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0008584 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0008584 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| YBX3 | YBX3 | P16989 | Y-box-binding protein 3 | chr12 | GO:0008584 | Not Cancer Driver | No | 49 | 0.132 | 359 | 47 | 0.131 | 0 |
| ZFP42_ENST00000509524 | ZFP42 | Q96MM3 | Zinc finger protein 42 homolog | chr4 | GO:0008584 | Not Cancer Driver | No | 135 | 0.435 | 76 | 27 | 0.355 | 0 |