Total number of protein in "GO:0007416" GO term: 79
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACHE_ENST00000241069 | ACHE | P22303 | Acetylcholinesterase | chr7 | GO:0007416 | Not Cancer Driver | No | 81 | 0.132 | 64 | 8 | 0.125 | 0 |
| ADD2_ENST00000407644 | ADD2 | P35612 | Beta-adducin | chr2 | GO:0007416 | Not Cancer Driver | No | 157 | 0.216 | 423 | 104 | 0.246 | 0 |
| ADGRF1 | ADGRF1 | Q5T601 | Adhesion G-protein coupled receptor F1 | chr6 | GO:0007416 | Not Cancer Driver | No | 159 | 0.175 | 8 | 0 | 0.0 | 0 |
| ADGRL3 | ADGRL3 | Q9HAR2 | Adhesion G protein-coupled receptor L3 | chr4 | GO:0007416 | Not Cancer Driver | No | 440 | 0.304 | 517 | 130 | 0.251 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0007416 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| BDNF_ENST00000439476 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0007416 | Not Cancer Driver | No | 47 | 0.19 | 79 | 19 | 0.241 | 1 |
| CBLN4 | CBLN4 | Q9NTU7 | Cerebellin-4 | chr20 | GO:0007416 | Not Cancer Driver | No | 62 | 0.308 | 20 | 10 | 0.5 | 0 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0007416 | Census, Compendium | Yes | 150 | 0.17 | 400 | 82 | 0.205 | 5 |
| CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0007416 | Not Cancer Driver | No | 238 | 0.263 | 461 | 130 | 0.282 | 7 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0007416 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CLSTN3 | CLSTN3 | Q9BQT9 | Calsyntenin-3 | chr12 | GO:0007416 | Not Cancer Driver | No | 140 | 0.146 | 211 | 27 | 0.128 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0007416 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0007416 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DNER | DNER | Q8NFT8 | Delta and Notch-like epidermal growth factor-related receptor | chr2 | GO:0007416 | Not Cancer Driver | No | 162 | 0.22 | 106 | 26 | 0.245 | 0 |
| DNM3_ENST00000355305 | DNM3 | Q9UQ16 | Dynamin-3 | chr1 | GO:0007416 | Not Cancer Driver | No | 166 | 0.191 | 257 | 45 | 0.175 | 0 |
| DRD1 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0007416 | Not Cancer Driver | No | 73 | 0.164 | 30 | 4 | 0.133 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0007416 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DSCAM | DSCAM | O60469 | Down syndrome cell adhesion molecule | chr21 | GO:0007416 | Not Cancer Driver | No | 652 | 0.324 | 603 | 201 | 0.333 | 0 |
| ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0007416 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
| FARP1_ENST00000319562 | FARP1 | Q9Y4F1 | FERM, ARHGEF and pleckstrin domain-containing protein 1 | chr13 | GO:0007416 | Not Cancer Driver | No | 147 | 0.141 | 315 | 60 | 0.19 | 0 |
| FBXO45 | FBXO45 | P0C2W1 | F-box/SPRY domain-containing protein 1 | chr3 | GO:0007416 | Not Cancer Driver | No | 28 | 0.098 | 10 | 0 | 0.0 | 0 |
| FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0007416 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
| FLRT3_ENST00000341420 | FLRT3 | Q9NZU0 | Leucine-rich repeat transmembrane protein FLRT3 | chr20 | GO:0007416 | Not Cancer Driver | No | 108 | 0.166 | 112 | 15 | 0.134 | 4 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0007416 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| GABRA1_ENST00000638112 | GABRA1 | P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | chr5 | GO:0007416 | Not Cancer Driver | No | 175 | 0.384 | 58 | 31 | 0.534 | 6 |
| GABRA2_ENST00000356504 | GABRA2 | P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | chr4 | GO:0007416 | Not Cancer Driver | No | 194 | 0.43 | 26 | 13 | 0.5 | 5 |
| GABRB2_ENST00000393959 | GABRB2 | P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | chr5 | GO:0007416 | Not Cancer Driver | No | 165 | 0.322 | 27 | 10 | 0.37 | 1 |
| GABRB3 | GABRB3 | P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | chr15 | GO:0007416 | Not Cancer Driver | No | 178 | 0.376 | 56 | 22 | 0.393 | 9 |
| GABRG2_ENST00000639213 | GABRG2 | P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | chr5 | GO:0007416 | Not Cancer Driver | No | 188 | 0.403 | 19 | 13 | 0.684 | 11 |
| GJA10 | GJA10 | Q969M2 | Gap junction alpha-10 protein | chr6 | GO:0007416 | Not Cancer Driver | No | 135 | 0.249 | 210 | 42 | 0.2 | 0 |
| GNPAT | GNPAT | O15228 | Dihydroxyacetone phosphate acyltransferase | chr1 | GO:0007416 | Not Cancer Driver | No | 86 | 0.126 | 6 | 3 | 0.5 | 3 |
| GPM6A_ENST00000393658 | GPM6A | P51674 | Neuronal membrane glycoprotein M6-a | chr4 | GO:0007416 | Not Cancer Driver | No | 83 | 0.299 | 15 | 5 | 0.333 | 0 |
| GRID2 | GRID2 | O43424 | Glutamate receptor ionotropic, delta-2 | chr4 | GO:0007416 | Not Cancer Driver | No | 350 | 0.348 | 155 | 35 | 0.226 | 3 |
| IGFN1_ENST00000295591 | IGFN1 | Q86VF2 | Immunoglobulin-like and fibronectin type III domain-containing protein 1 | chr1 | GO:0007416 | Not Cancer Driver | No | 194 | 0.155 | 565 | 97 | 0.172 | 0 |
| KIRREL3 | KIRREL3 | Q8IZU9 | Kin of IRRE-like protein 3 | chr11 | GO:0007416 | Not Cancer Driver | No | 111 | 0.143 | 223 | 32 | 0.143 | 0 |
| LGI2 | LGI2 | Q8N0V4 | Leucine-rich repeat LGI family member 2 | chr4 | GO:0007416 | Not Cancer Driver | No | 96 | 0.176 | 0 | 0 | 0.0 | 0 |
| LRP4 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 | chr11 | GO:0007416 | Not Cancer Driver | No | 233 | 0.122 | 265 | 28 | 0.106 | 11 |
| LRRC4 | LRRC4 | Q9HBW1 | Leucine-rich repeat-containing protein 4 | chr7 | GO:0007416 | Not Cancer Driver | No | 117 | 0.179 | 110 | 14 | 0.127 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0007416 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0007416 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| NLGN1_ENST00000361589 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0007416 | Not Cancer Driver | No | 214 | 0.248 | 248 | 61 | 0.246 | 4 |
| NLGN2 | NLGN2 | Q8NFZ4 | Neuroligin-2 | chr17 | GO:0007416 | Not Cancer Driver | No | 91 | 0.109 | 300 | 19 | 0.063 | 0 |
| NLGN3 | NLGN3 | Q9NZ94 | Neuroligin-3 | chrX | GO:0007416 | Not Cancer Driver | No | 158 | 0.186 | 257 | 54 | 0.21 | 2 |
| NPAS4 | NPAS4 | Q8IUM7 | Neuronal PAS domain-containing protein 4 | chr11 | GO:0007416 | Not Cancer Driver | No | 229 | 0.286 | 429 | 114 | 0.266 | 0 |
| NPTN | NPTN | Q9Y639 | Neuroplastin | chr15 | GO:0007416 | Not Cancer Driver | No | 47 | 0.118 | 118 | 9 | 0.076 | 0 |
| NRCAM_ENST00000425651 | NRCAM | Q92823 | Neuronal cell adhesion molecule | chr7 | GO:0007416 | Not Cancer Driver | No | 210 | 0.161 | 471 | 75 | 0.159 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0007416 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NRXN1_ENST00000406316 | NRXN1 | Q9ULB1 | Neurexin-1 | chr2 | GO:0007416 | Not Cancer Driver | No | 593 | 0.401 | 301 | 110 | 0.365 | 0 |
| NRXN2_ENST00000377551 | NRXN2 | Q9P2S2 | Neurexin-2 | chr11 | GO:0007416 | Not Cancer Driver | No | 278 | 0.162 | 547 | 80 | 0.146 | 0 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | GO:0007416 | Not Cancer Driver | No | 233 | 0.123 | 553 | 60 | 0.108 | 0 |
| PCDHB10 | PCDHB10 | Q9UN67 | Protocadherin beta-10 | chr5 | GO:0007416 | Not Cancer Driver | No | 240 | 0.3 | 124 | 31 | 0.25 | 0 |
| PCDHB11 | PCDHB11 | Q9Y5F2 | Protocadherin beta-11 | chr5 | GO:0007416 | Not Cancer Driver | No | 230 | 0.289 | 91 | 19 | 0.209 | 0 |
| PCDHB13 | PCDHB13 | Q9Y5F0 | Protocadherin beta-13 | chr5 | GO:0007416 | Not Cancer Driver | No | 205 | 0.257 | 115 | 30 | 0.261 | 0 |
| PCDHB14 | PCDHB14 | Q9Y5E9 | Protocadherin beta-14 | chr5 | GO:0007416 | Not Cancer Driver | No | 220 | 0.276 | 60 | 15 | 0.25 | 0 |
| PCDHB16 | PCDHB16 | Q9NRJ7 | Protocadherin beta-16 | chr5 | GO:0007416 | Not Cancer Driver | No | 214 | 0.276 | 247 | 70 | 0.283 | 0 |
| PCDHB2 | PCDHB2 | Q9Y5E7 | Protocadherin beta-2 | chr5 | GO:0007416 | Not Cancer Driver | No | 258 | 0.323 | 78 | 18 | 0.231 | 0 |
| PCDHB3 | PCDHB3 | Q9Y5E6 | Protocadherin beta-3 | chr5 | GO:0007416 | Not Cancer Driver | No | 258 | 0.324 | 119 | 30 | 0.252 | 0 |
| PCDHB4 | PCDHB4 | Q9Y5E5 | Protocadherin beta-4 | chr5 | GO:0007416 | Not Cancer Driver | No | 249 | 0.313 | 125 | 33 | 0.264 | 0 |
| PCDHB5 | PCDHB5 | Q9Y5E4 | Protocadherin beta-5 | chr5 | GO:0007416 | Not Cancer Driver | No | 271 | 0.341 | 185 | 61 | 0.33 | 0 |
| PCDHB6 | PCDHB6 | Q9Y5E3 | Protocadherin beta-6 | chr5 | GO:0007416 | Not Cancer Driver | No | 262 | 0.33 | 142 | 39 | 0.275 | 0 |
| PCDHB9 | PCDHB9 | Q9Y5E1 | Protocadherin beta-9 | chr5 | GO:0007416 | Not Cancer Driver | No | 84 | 0.105 | 127 | 15 | 0.118 | 0 |
| PLXNB1_ENST00000296440 | PLXNB1 | O43157 | Plexin-B1 | chr3 | GO:0007416 | Not Cancer Driver | No | 228 | 0.107 | 684 | 67 | 0.098 | 0 |
| PLXNB2_ENST00000359337 | PLXNB2 | O15031 | Plexin-B2 | chr22 | GO:0007416 | Not Cancer Driver | No | 273 | 0.149 | 304 | 35 | 0.115 | 0 |
| PLXND1 | PLXND1 | Q9Y4D7 | Plexin-D1 | chr3 | GO:0007416 | Not Cancer Driver | No | 246 | 0.128 | 321 | 35 | 0.109 | 0 |
| POU4F1 | POU4F1 | Q01851 | POU domain, class 4, transcription factor 1 | chr13 | GO:0007416 | Not Cancer Driver | No | 51 | 0.122 | 273 | 34 | 0.125 | 1 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0007416 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RAB29 | RAB29 | O14966 | Ras-related protein Rab-7L1 | chr1 | GO:0007416 | Not Cancer Driver | No | 28 | 0.138 | 18 | 3 | 0.167 | 0 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0007416 | Not Cancer Driver | No | 55 | 0.091 | 85 | 4 | 0.047 | 0 |
| SDK1 | SDK1 | Q7Z5N4 | Protein sidekick-1 | chr7 | GO:0007416 | Not Cancer Driver | No | 526 | 0.238 | 784 | 179 | 0.228 | 0 |
| SDK2 | SDK2 | Q58EX2 | Protein sidekick-2 | chr17 | GO:0007416 | Not Cancer Driver | No | 330 | 0.152 | 850 | 131 | 0.154 | 0 |
| SHANK2_ENST00000601538 | SHANK2 | Q9UPX8 | SH3 and multiple ankyrin repeat domains protein 2 | chr11 | GO:0007416 | Not Cancer Driver | No | 303 | 0.164 | 1379 | 262 | 0.19 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | GO:0007416 | Not Cancer Driver | No | 37 | 0.089 | 96 | 2 | 0.021 | 4 |
| SLITRK1 | SLITRK1 | Q96PX8 | SLIT and NTRK-like protein 1 | chr13 | GO:0007416 | Not Cancer Driver | No | 299 | 0.43 | 126 | 64 | 0.508 | 0 |
| SLITRK6_ENST00000643778 | SLITRK6 | Q9H5Y7 | SLIT and NTRK-like protein 6 | chr13 | GO:0007416 | Not Cancer Driver | No | 244 | 0.29 | 225 | 53 | 0.236 | 0 |
| SPOCK2_ENST00000317376 | SPOCK2 | Q92563 | Testican-2 | chr10 | GO:0007416 | Not Cancer Driver | No | 48 | 0.113 | 113 | 8 | 0.071 | 0 |
| SPTBN2 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | GO:0007416 | Not Cancer Driver | No | 317 | 0.133 | 877 | 126 | 0.144 | 2 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0007416 | Not Cancer Driver | No | 68 | 0.085 | 99 | 9 | 0.091 | 1 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0007416 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0007416 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |