Total number of protein in "GO:0007368" GO term: 69
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0007368 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| ACVR2A_ENST00000404590 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0007368 | Census, Compendium | Yes | 98 | 0.191 | 56 | 6 | 0.107 | 0 |
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0007368 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
| ALG5 | ALG5 | Q9Y673 | Dolichyl-phosphate beta-glucosyltransferase | chr13 | GO:0007368 | Not Cancer Driver | No | 40 | 0.123 | 0 | 0 | 0.0 | 0 |
| ANKS6 | ANKS6 | Q68DC2 | Ankyrin repeat and SAM domain-containing protein 6 | chr9 | GO:0007368 | Not Cancer Driver | No | 94 | 0.108 | 568 | 60 | 0.106 | 2 |
| AP1B1 | AP1B1 | Q10567 | AP-1 complex subunit beta-1 | chr22 | GO:0007368 | Not Cancer Driver | No | 114 | 0.12 | 119 | 10 | 0.084 | 1 |
| ARL6 | ARL6 | Q9H0F7 | ADP-ribosylation factor-like protein 6 | chr3 | GO:0007368 | Not Cancer Driver | No | 29 | 0.156 | 4 | 0 | 0.0 | 6 |
| ARMC4 | ODAD2 | Q5T2S8 | Outer dynein arm-docking complex subunit 2 | chr10 | GO:0007368 | Not Cancer Driver | No | 288 | 0.276 | 155 | 33 | 0.213 | 1 |
| BBS7 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | GO:0007368 | Not Cancer Driver | No | 99 | 0.138 | 56 | 8 | 0.143 | 4 |
| BICC1 | BICC1 | Q9H694 | Protein bicaudal C homolog 1 | chr10 | GO:0007368 | Not Cancer Driver | No | 171 | 0.176 | 645 | 115 | 0.178 | 1 |
| CC2D2A | CC2D2A | Q9P2K1 | Coiled-coil and C2 domain-containing protein 2A | chr4 | GO:0007368 | Not Cancer Driver | No | 165 | 0.102 | 676 | 78 | 0.115 | 22 |
| CCDC103 | CCDC103 | Q8IW40 | Coiled-coil domain-containing protein 103 | chr17 | GO:0007368 | Not Cancer Driver | No | 22 | 0.091 | 78 | 8 | 0.103 | 0 |
| CCDC151 | ODAD3 | A5D8V7 | Outer dynein arm-docking complex subunit 3 | chr19 | GO:0007368 | Not Cancer Driver | No | 68 | 0.114 | 361 | 43 | 0.119 | 0 |
| CCDC39 | CCDC39 | Q9UFE4 | Coiled-coil domain-containing protein 39 | chr3 | GO:0007368 | Not Cancer Driver | No | 204 | 0.217 | 497 | 89 | 0.179 | 0 |
| CCDC40 | CCDC40 | Q4G0X9 | Coiled-coil domain-containing protein 40 | chr17 | GO:0007368 | Not Cancer Driver | No | 201 | 0.176 | 672 | 123 | 0.183 | 0 |
| CFAP45 | CFAP45 | Q9UL16 | Cilia- and flagella-associated protein 45 | chr1 | GO:0007368 | Not Cancer Driver | No | 126 | 0.229 | 493 | 120 | 0.243 | 0 |
| CFAP52 | CFAP52 | Q8N1V2 | Cilia- and flagella-associated protein 52 | chr17 | GO:0007368 | Not Cancer Driver | No | 107 | 0.173 | 4 | 0 | 0.0 | 0 |
| CFAP53 | CFAP53 | Q96M91 | Cilia- and flagella-associated protein 53 | chr18 | GO:0007368 | Not Cancer Driver | No | 96 | 0.187 | 383 | 78 | 0.204 | 0 |
| CFC1 | CFC1 | P0CG37 | Cryptic protein | chr2 | GO:0007368 | Not Cancer Driver | No | 25 | 0.112 | 68 | 23 | 0.338 | 1 |
| CFC1B | CFC1B | P0CG36 | Cryptic family protein 1B | chr2 | GO:0007368 | Not Cancer Driver | No | 2 | 0.009 | 55 | 1 | 0.018 | 0 |
| CITED2_ENST00000367651 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0007368 | Not Cancer Driver | No | 23 | 0.085 | 230 | 18 | 0.078 | 0 |
| DAAM2 | DAAM2 | Q86T65 | Disheveled-associated activator of morphogenesis 2 | chr6 | GO:0007368 | Not Cancer Driver | No | 183 | 0.171 | 272 | 55 | 0.202 | 0 |
| DAND5 | DAND5 | Q8N907 | DAN domain family member 5 | chr19 | GO:0007368 | Not Cancer Driver | No | 32 | 0.169 | 26 | 3 | 0.115 | 0 |
| DAW1 | DAW1 | Q8N136 | Dynein assembly factor with WDR repeat domains 1 | chr2 | GO:0007368 | Not Cancer Driver | No | 88 | 0.212 | 0 | 0 | 0.0 | 0 |
| DISP1 | DISP1 | Q96F81 | Protein dispatched homolog 1 | chr1 | GO:0007368 | Not Cancer Driver | No | 212 | 0.139 | 252 | 35 | 0.139 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0007368 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
| DNAAF1 | DNAAF1 | Q8NEP3 | Dynein axonemal assembly factor 1 | chr16 | GO:0007368 | Not Cancer Driver | No | 107 | 0.148 | 513 | 71 | 0.138 | 1 |
| DNAAF2 | DNAAF2 | Q9NVR5 | Protein kintoun | chr14 | GO:0007368 | Not Cancer Driver | No | 77 | 0.092 | 579 | 37 | 0.064 | 0 |
| DNAAF4_ENST00000348518 | DNAAF4 | Q8WXU2 | Dynein axonemal assembly factor 4 | chr15 | GO:0007368 | Not Cancer Driver | No | 63 | 0.15 | 177 | 20 | 0.113 | 0 |
| DNAH11 | DNAH11 | Q96DT5 | Dynein axonemal heavy chain 11 | chr7 | GO:0007368 | Not Cancer Driver | No | 885 | 0.196 | 221 | 36 | 0.163 | 3 |
| DNAH5 | DNAH5 | Q8TE73 | Dynein axonemal heavy chain 5 | chr5 | GO:0007368 | Not Cancer Driver | No | 1431 | 0.309 | 296 | 111 | 0.375 | 12 |
| DNAI1_ENST00000242317 | DNAI1 | Q9UI46 | Dynein axonemal intermediate chain 1 | chr9 | GO:0007368 | Not Cancer Driver | No | 115 | 0.165 | 297 | 49 | 0.165 | 1 |
| DNAI2 | DNAI2 | Q9GZS0 | Dynein axonemal intermediate chain 2 | chr17 | GO:0007368 | Not Cancer Driver | No | 136 | 0.225 | 209 | 47 | 0.225 | 0 |
| DPCD | DPCD | Q9BVM2 | Protein DPCD | chr10 | GO:0007368 | Not Cancer Driver | No | 20 | 0.099 | 24 | 1 | 0.042 | 0 |
| DRC1 | DRC1 | Q96MC2 | Dynein regulatory complex protein 1 | chr2 | GO:0007368 | Not Cancer Driver | No | 119 | 0.161 | 245 | 44 | 0.18 | 0 |
| DYNC2H1_ENST00000375735 | DYNC2H1 | Q8NCM8 | Cytoplasmic dynein 2 heavy chain 1 | chr11 | GO:0007368 | Not Cancer Driver | No | 510 | 0.118 | 282 | 15 | 0.053 | 34 |
| DYNC2LI1_ENST00000260605 | DYNC2LI1 | Q8TCX1 | Cytoplasmic dynein 2 light intermediate chain 1 | chr2 | GO:0007368 | Not Cancer Driver | No | 53 | 0.151 | 93 | 8 | 0.086 | 2 |
| ENKUR | ENKUR | Q8TC29 | Enkurin | chr10 | GO:0007368 | Not Cancer Driver | No | 53 | 0.207 | 157 | 39 | 0.248 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0007368 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FOXF1 | FOXF1 | Q12946 | Forkhead box protein F1 | chr16 | GO:0007368 | Not Cancer Driver | No | 56 | 0.148 | 194 | 20 | 0.103 | 20 |
| FOXJ1 | FOXJ1 | Q92949 | Forkhead box protein J1 | chr17 | GO:0007368 | Not Cancer Driver | No | 25 | 0.059 | 279 | 18 | 0.065 | 0 |
| GALNT11_ENST00000430044 | GALNT11 | Q8NCW6 | Polypeptide N-acetylgalactosaminyltransferase 11 | chr7 | GO:0007368 | Not Cancer Driver | No | 73 | 0.12 | 91 | 18 | 0.198 | 0 |
| GAS8 | GAS8 | O95995 | Dynein regulatory complex subunit 4 | chr16 | GO:0007368 | Not Cancer Driver | No | 54 | 0.113 | 232 | 29 | 0.125 | 1 |
| IFT140 | IFT140 | Q96RY7 | Intraflagellar transport protein 140 homolog | chr16 | GO:0007368 | Not Cancer Driver | No | 176 | 0.12 | 161 | 27 | 0.168 | 10 |
| IFT74_ENST00000433700 | IFT74 | Q96LB3 | Intraflagellar transport protein 74 homolog | chr9 | GO:0007368 | Not Cancer Driver | No | 47 | 0.078 | 490 | 38 | 0.078 | 0 |
| KIF3B | KIF3B | O15066 | Kinesin-like protein KIF3B | chr20 | GO:0007368 | Not Cancer Driver | No | 105 | 0.141 | 485 | 69 | 0.142 | 2 |
| LEFTY1 | LEFTY1 | O75610 | Left-right determination factor 1 | chr1 | GO:0007368 | Not Cancer Driver | No | 55 | 0.15 | 65 | 8 | 0.123 | 0 |
| MEGF8 | MEGF8 | Q7Z7M0 | Multiple epidermal growth factor-like domains protein 8 | chr19 | GO:0007368 | Not Cancer Driver | No | 363 | 0.128 | 476 | 59 | 0.124 | 3 |
| MKKS | MKKS | Q9NPJ1 | McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin | chr20 | GO:0007368 | Not Cancer Driver | No | 56 | 0.098 | 6 | 1 | 0.167 | 22 |
| MKS1 | MKS1 | Q9NXB0 | Meckel syndrome type 1 protein | chr17 | GO:0007368 | Not Cancer Driver | No | 82 | 0.147 | 152 | 23 | 0.151 | 2 |
| MMP21 | MMP21 | Q8N119 | Matrix metalloproteinase-21 | chr10 | GO:0007368 | Not Cancer Driver | No | 75 | 0.132 | 147 | 11 | 0.075 | 8 |
| NEK8 | NEK8 | Q86SG6 | Serine/threonine-protein kinase Nek8 | chr17 | GO:0007368 | Not Cancer Driver | No | 102 | 0.147 | 167 | 40 | 0.24 | 3 |
| NKX3-2 | NKX3-2 | P78367 | Homeobox protein Nkx-3.2 | chr4 | GO:0007368 | Not Cancer Driver | No | 36 | 0.108 | 212 | 27 | 0.127 | 0 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0007368 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NPHP3 | NPHP3 | Q7Z494 | Nephrocystin-3 | chr3 | GO:0007368 | Not Cancer Driver | No | 129 | 0.097 | 249 | 26 | 0.104 | 7 |
| PCSK6 | PCSK6 | P29122 | Proprotein convertase subtilisin/kexin type 6 | chr15 | GO:0007368 | Not Cancer Driver | No | 138 | 0.142 | 207 | 45 | 0.217 | 0 |
| PITX2_ENST00000354925 | PITX2 | Q99697 | Pituitary homeobox 2 | chr4 | GO:0007368 | Not Cancer Driver | No | 74 | 0.233 | 185 | 43 | 0.232 | 13 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0007368 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PSKH1 | PSKH1 | P11801 | Serine/threonine-protein kinase H1 | chr16 | GO:0007368 | Not Cancer Driver | No | 56 | 0.132 | 122 | 24 | 0.197 | 0 |
| RIPPLY2 | RIPPLY2 | Q5TAB7 | Protein ripply2 | chr6 | GO:0007368 | Not Cancer Driver | No | 24 | 0.188 | 82 | 15 | 0.183 | 0 |
| RPGRIP1L_ENST00000379925 | RPGRIP1L | Q68CZ1 | Protein fantom | chr16 | GO:0007368 | Not Cancer Driver | No | 177 | 0.135 | 586 | 94 | 0.16 | 8 |
| RTTN | RTTN | Q86VV8 | Rotatin | chr18 | GO:0007368 | Not Cancer Driver | No | 250 | 0.112 | 161 | 27 | 0.168 | 2 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0007368 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0007368 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| STIL_ENST00000360380 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | GO:0007368 | Census, Compendium | Yes | 147 | 0.114 | 735 | 85 | 0.116 | 1 |
| TBC1D32 | TBC1D32 | Q96NH3 | Protein broad-minded | chr6 | GO:0007368 | Not Cancer Driver | No | 173 | 0.138 | 110 | 19 | 0.173 | 0 |
| TBX1_ENST00000329705 | TBX1 | O43435 | T-box transcription factor TBX1 | chr22 | GO:0007368 | Not Cancer Driver | No | 35 | 0.088 | 197 | 12 | 0.061 | 4 |
| TDGF1 | TDGF1 | P13385 | Teratocarcinoma-derived growth factor 1 | chr3 | GO:0007368 | Not Cancer Driver | No | 39 | 0.207 | 25 | 2 | 0.08 | 0 |
| ZIC3 | ZIC3 | O60481 | Zinc finger protein ZIC 3 | chrX | GO:0007368 | Not Cancer Driver | No | 100 | 0.214 | 327 | 66 | 0.202 | 10 |