Total number of protein in "GO:0007281" GO term: 81
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0007281 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0007281 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0007281 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
| ASPM | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0007281 | Not Cancer Driver | No | 554 | 0.159 | 424 | 67 | 0.158 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0007281 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| AURKC | AURKC | Q9UQB9 | Aurora kinase C | chr19 | GO:0007281 | Not Cancer Driver | No | 70 | 0.227 | 43 | 5 | 0.116 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0007281 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0007281 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0007281 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BHMG1 | MEIOSIN | C9JSJ3 | Meiosis initiator protein | chr19 | GO:0007281 | Not Cancer Driver | No | 0 | 0.0 | 498 | 0 | 0.0 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0007281 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| C14orf39 | SIX6OS1 | Q8N1H7 | Protein SIX6OS1 | chr14 | GO:0007281 | Not Cancer Driver | No | 128 | 0.218 | 326 | 76 | 0.233 | 0 |
| CCDC155 | KASH5 | Q8N6L0 | Protein KASH5 | chr19 | GO:0007281 | Not Cancer Driver | No | 88 | 0.157 | 401 | 70 | 0.175 | 0 |
| CCDC36_ENST00000452691 | IHO1 | Q8IYA8 | Interactor of HORMAD1 protein 1 | chr3 | GO:0007281 | Not Cancer Driver | No | 83 | 0.14 | 355 | 43 | 0.121 | 0 |
| CELF1_ENST00000358597 | CELF1 | Q92879 | CUGBP Elav-like family member 1 | chr11 | GO:0007281 | Not Cancer Driver | No | 56 | 0.115 | 166 | 17 | 0.102 | 0 |
| CELF4 | CELF4 | Q9BZC1 | CUGBP Elav-like family member 4 | chr18 | GO:0007281 | Not Cancer Driver | No | 107 | 0.22 | 253 | 74 | 0.292 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0007281 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| DAZL_ENST00000399444 | DAZL | Q92904 | Deleted in azoospermia-like | chr3 | GO:0007281 | Not Cancer Driver | No | 28 | 0.095 | 128 | 12 | 0.094 | 0 |
| DDX20 | DDX20 | Q9UHI6 | Probable ATP-dependent RNA helicase DDX20 | chr1 | GO:0007281 | Not Cancer Driver | No | 89 | 0.108 | 299 | 33 | 0.11 | 0 |
| DEAF1 | DEAF1 | O75398 | Deformed epidermal autoregulatory factor 1 homolog | chr11 | GO:0007281 | Not Cancer Driver | No | 75 | 0.133 | 370 | 51 | 0.138 | 4 |
| DIAPH2 | DIAPH2 | O60879 | Protein diaphanous homolog 2 | chrX | GO:0007281 | Not Cancer Driver | No | 195 | 0.177 | 460 | 95 | 0.207 | 0 |
| DMRT1 | DMRT1 | Q9Y5R6 | Doublesex- and mab-3-related transcription factor 1 | chr9 | GO:0007281 | Not Cancer Driver | No | 60 | 0.161 | 282 | 47 | 0.167 | 0 |
| DMRTA1 | DMRTA1 | Q5VZB9 | Doublesex- and mab-3-related transcription factor A1 | chr9 | GO:0007281 | Not Cancer Driver | No | 50 | 0.099 | 276 | 25 | 0.091 | 0 |
| DMRTB1 | DMRTB1 | Q96MA1 | Doublesex- and mab-3-related transcription factor B1 | chr1 | GO:0007281 | Not Cancer Driver | No | 61 | 0.178 | 284 | 48 | 0.169 | 0 |
| DMRTC2 | DMRTC2 | Q8IXT2 | Doublesex- and mab-3-related transcription factor C2 | chr19 | GO:0007281 | Not Cancer Driver | No | 45 | 0.123 | 310 | 35 | 0.113 | 0 |
| DND1 | DND1 | Q8IYX4 | Dead end protein homolog 1 | chr5 | GO:0007281 | Not Cancer Driver | No | 23 | 0.065 | 36 | 0 | 0.0 | 0 |
| DZIP1_ENST00000376829 | DZIP1 | Q86YF9 | Cilium assembly protein DZIP1 | chr13 | GO:0007281 | Not Cancer Driver | No | 143 | 0.165 | 523 | 92 | 0.176 | 2 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0007281 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| FANCC | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | GO:0007281 | Census, Compendium | Yes | 66 | 0.118 | 13 | 1 | 0.077 | 3 |
| FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | GO:0007281 | Not Cancer Driver | No | 75 | 0.138 | 20 | 3 | 0.15 | 7 |
| FIGLA | FIGLA | Q6QHK4 | Factor in the germline alpha | chr2 | GO:0007281 | Not Cancer Driver | No | 22 | 0.1 | 154 | 17 | 0.11 | 0 |
| FMN2 | FMN2 | Q9NZ56 | Formin-2 | chr1 | GO:0007281 | Not Cancer Driver | No | 614 | 0.357 | 1322 | 475 | 0.359 | 0 |
| GMCL1 | GMCL1 | Q96IK5 | Germ cell-less protein-like 1 | chr2 | GO:0007281 | Not Cancer Driver | No | 33 | 0.064 | 80 | 2 | 0.025 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0007281 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0007281 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HEXB | HEXB | P07686 | Beta-hexosaminidase subunit beta | chr5 | GO:0007281 | Not Cancer Driver | No | 45 | 0.081 | 0 | 0 | 0.0 | 9 |
| HORMAD1 | HORMAD1 | Q86X24 | HORMA domain-containing protein 1 | chr1 | GO:0007281 | Not Cancer Driver | No | 76 | 0.193 | 178 | 31 | 0.174 | 0 |
| INHBB | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0007281 | Not Cancer Driver | No | 61 | 0.15 | 98 | 5 | 0.051 | 0 |
| KMT2D | KMT2D | O14686 | Histone-lysine N-methyltransferase 2D | chr12 | GO:0007281 | Census, Compendium | Yes | 773 | 0.14 | 4386 | 552 | 0.126 | 13 |
| LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0007281 | Not Cancer Driver | No | 37 | 0.177 | 86 | 12 | 0.14 | 0 |
| MARF1 | MARF1 | Q9Y4F3 | Meiosis regulator and mRNA stability factor 1 | chr16 | GO:0007281 | Not Cancer Driver | No | 199 | 0.114 | 524 | 73 | 0.139 | 0 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0007281 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MEI4 | MEI4 | A8MW99 | Meiosis-specific protein MEI4 | chr6 | GO:0007281 | Not Cancer Driver | No | 0 | 0.0 | 69 | 0 | 0.0 | 0 |
| MEIOC | MEIOC | A2RUB1 | Meiosis-specific coiled-coil domain-containing protein MEIOC | chr17 | GO:0007281 | Not Cancer Driver | No | 92 | 0.097 | 529 | 54 | 0.102 | 0 |
| METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0007281 | Not Cancer Driver | No | 74 | 0.128 | 274 | 29 | 0.106 | 0 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0007281 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MOV10L1_ENST00000545383 | MOV10L1 | Q9BXT6 | RNA helicase Mov10l1 | chr22 | GO:0007281 | Not Cancer Driver | No | 184 | 0.152 | 178 | 21 | 0.118 | 0 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0007281 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0007281 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| NANOS1 | NANOS1 | Q8WY41 | Nanos homolog 1 | chr10 | GO:0007281 | Not Cancer Driver | No | 7 | 0.024 | 169 | 2 | 0.012 | 0 |
| NANOS2 | NANOS2 | P60321 | Nanos homolog 2 | chr19 | GO:0007281 | Not Cancer Driver | No | 29 | 0.21 | 50 | 11 | 0.22 | 0 |
| NANOS3_ENST00000397555 | NANOS3 | P60323 | Nanos homolog 3 | chr19 | GO:0007281 | Not Cancer Driver | No | 31 | 0.179 | 117 | 25 | 0.214 | 0 |
| NOBOX | NOBOX | O60393 | Homeobox protein NOBOX | chr7 | GO:0007281 | Not Cancer Driver | No | 127 | 0.184 | 615 | 110 | 0.179 | 3 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0007281 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | GO:0007281 | Not Cancer Driver | No | 54 | 0.127 | 45 | 7 | 0.156 | 2 |
| PAQR5 | PAQR5 | Q9NXK6 | Membrane progestin receptor gamma | chr15 | GO:0007281 | Not Cancer Driver | No | 44 | 0.133 | 2 | 0 | 0.0 | 0 |
| PAQR7 | PAQR7 | Q86WK9 | Membrane progestin receptor alpha | chr1 | GO:0007281 | Not Cancer Driver | No | 32 | 0.092 | 0 | 0 | 0.0 | 0 |
| PAQR8 | PAQR8 | Q8TEZ7 | Membrane progestin receptor beta | chr6 | GO:0007281 | Not Cancer Driver | No | 45 | 0.127 | 0 | 0 | 0.0 | 0 |
| PIWIL2_ENST00000454009 | PIWIL2 | Q8TC59 | Piwi-like protein 2 | chr8 | GO:0007281 | Not Cancer Driver | No | 138 | 0.142 | 232 | 38 | 0.164 | 0 |
| PRDM1 | PRDM1 | O75626 | PR domain zinc finger protein 1 | chr6 | GO:0007281 | Census, Compendium | Yes | 145 | 0.176 | 337 | 66 | 0.196 | 0 |
| PRDM14 | PRDM14 | Q9GZV8 | PR domain zinc finger protein 14 | chr8 | GO:0007281 | Not Cancer Driver | No | 122 | 0.214 | 179 | 37 | 0.207 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0007281 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0007281 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | GO:0007281 | Not Cancer Driver | No | 40 | 0.119 | 203 | 22 | 0.108 | 0 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0007281 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| SEBOX | SEBOX | Q9HB31 | Homeobox protein SEBOX | chr17 | GO:0007281 | Not Cancer Driver | No | 16 | 0.084 | 123 | 10 | 0.081 | 0 |
| SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0007281 | Not Cancer Driver | No | 44 | 0.095 | 172 | 11 | 0.064 | 0 |
| SPO11 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0007281 | Not Cancer Driver | No | 59 | 0.149 | 26 | 5 | 0.192 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007281 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| STRA8 | STRA8 | Q7Z7C7 | Stimulated by retinoic acid gene 8 protein homolog | chr7 | GO:0007281 | Not Cancer Driver | No | 45 | 0.136 | 105 | 15 | 0.143 | 0 |
| TAF4B_ENST00000269142 | TAF4B | Q92750 | Transcription initiation factor TFIID subunit 4B | chr18 | GO:0007281 | Not Cancer Driver | No | 86 | 0.1 | 482 | 46 | 0.095 | 0 |
| TCP11_ENST00000512012 | TCP11 | Q8WWU5 | T-complex protein 11 homolog | chr6 | GO:0007281 | Not Cancer Driver | No | 78 | 0.155 | 112 | 13 | 0.116 | 0 |
| TDRD1 | TDRD1 | Q9BXT4 | Tudor domain-containing protein 1 | chr10 | GO:0007281 | Not Cancer Driver | No | 200 | 0.169 | 216 | 27 | 0.125 | 0 |
| TIAL1_ENST00000436547 | TIAL1 | Q01085 | Nucleolysin TIAR | chr10 | GO:0007281 | Not Cancer Driver | No | 45 | 0.12 | 122 | 12 | 0.098 | 0 |
| TRIP13 | TRIP13 | Q15645 | Pachytene checkpoint protein 2 homolog | chr5 | GO:0007281 | Not Cancer Driver | No | 62 | 0.144 | 30 | 6 | 0.2 | 1 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0007281 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| YBX2 | YBX2 | Q9Y2T7 | Y-box-binding protein 2 | chr17 | GO:0007281 | Not Cancer Driver | No | 48 | 0.132 | 342 | 46 | 0.135 | 0 |
| YTHDC2 | YTHDC2 | Q9H6S0 | 3'-5' RNA helicase YTHDC2 | chr5 | GO:0007281 | Not Cancer Driver | No | 163 | 0.114 | 439 | 48 | 0.109 | 0 |
| ZFY_ENST00000155093 | ZFY | P08048 | Zinc finger Y-chromosomal protein | chrY | GO:0007281 | Not Cancer Driver | No | 29 | 0.036 | 357 | 8 | 0.022 | 0 |
| ZGLP1 | ZGLP1 | P0C6A0 | GATA-type zinc finger protein 1 | chr19 | GO:0007281 | Not Cancer Driver | No | 24 | 0.089 | 191 | 17 | 0.089 | 0 |
| ZP3 | ZP3 | P21754 | Zona pellucida sperm-binding protein 3 | chr7 | GO:0007281 | Not Cancer Driver | No | 55 | 0.13 | 56 | 11 | 0.196 | 1 |