Total number of protein in "GO:0007229" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0007229 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0007229 | Not Cancer Driver | No | 88 | 0.118 | 156 | 20 | 0.128 | 4 |
| ADAM11 | ADAM11 | O75078 | Disintegrin and metalloproteinase domain-containing protein 11 | chr17 | GO:0007229 | Not Cancer Driver | No | 98 | 0.127 | 163 | 17 | 0.104 | 0 |
| ADAM15 | ADAM15 | Q13444 | Disintegrin and metalloproteinase domain-containing protein 15 | chr1 | GO:0007229 | Not Cancer Driver | No | 104 | 0.121 | 213 | 29 | 0.136 | 0 |
| ADAM9 | ADAM9 | Q13443 | Disintegrin and metalloproteinase domain-containing protein 9 | chr8 | GO:0007229 | Not Cancer Driver | No | 86 | 0.105 | 129 | 13 | 0.101 | 0 |
| ADAMTS1 | ADAMTS1 | Q9UHI8 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | chr21 | GO:0007229 | Not Cancer Driver | No | 135 | 0.14 | 272 | 32 | 0.118 | 0 |
| ADAMTS13 | ADAMTS13 | Q76LX8 | A disintegrin and metalloproteinase with thrombospondin motifs 13 | chr9 | GO:0007229 | Not Cancer Driver | No | 172 | 0.121 | 285 | 35 | 0.123 | 43 |
| ANGPTL3 | ANGPTL3 | Q9Y5C1 | Angiopoietin-related protein 3 | chr1 | GO:0007229 | Not Cancer Driver | No | 52 | 0.113 | 154 | 26 | 0.169 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0007229 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0007229 | Not Cancer Driver | No | 108 | 0.124 | 677 | 75 | 0.111 | 0 |
| CCM2_ENST00000258781 | CCM2 | Q9BSQ5 | Cerebral cavernous malformations 2 protein | chr7 | GO:0007229 | Not Cancer Driver | No | 58 | 0.131 | 132 | 8 | 0.061 | 3 |
| CCN2 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0007229 | Not Cancer Driver | No | 58 | 0.166 | 0 | 0 | 0.0 | 0 |
| CD40LG | CD40LG | P29965 | CD40 ligand | chrX | GO:0007229 | Not Cancer Driver | No | 56 | 0.215 | 24 | 7 | 0.292 | 32 |
| CD47 | CD47 | Q08722 | Leukocyte surface antigen CD47 | chr3 | GO:0007229 | Not Cancer Driver | No | 37 | 0.115 | 0 | 0 | 0.0 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0007229 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDH17 | CDH17 | Q12864 | Cadherin-17 | chr8 | GO:0007229 | Census | Yes | 166 | 0.2 | 186 | 35 | 0.188 | 0 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0007229 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| COL16A1 | COL16A1 | Q07092 | Collagen alpha-1(XVI) chain | chr1 | GO:0007229 | Not Cancer Driver | No | 192 | 0.12 | 1381 | 163 | 0.118 | 0 |
| COL3A1 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0007229 | Census | Yes | 402 | 0.274 | 1182 | 337 | 0.285 | 103 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0007229 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0007229 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DOCK1_ENST00000280333 | DOCK1 | Q14185 | Dedicator of cytokinesis protein 1 | chr10 | GO:0007229 | Not Cancer Driver | No | 240 | 0.129 | 360 | 52 | 0.144 | 0 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0007229 | Not Cancer Driver | No | 167 | 0.118 | 967 | 118 | 0.122 | 0 |
| FBLN1 | FBLN1 | P23142 | Fibulin-1 | chr22 | GO:0007229 | Compendium | Yes | 122 | 0.174 | 22 | 3 | 0.136 | 0 |
| FERMT1 | FERMT1 | Q9BQL6 | Fermitin family homolog 1 | chr20 | GO:0007229 | Not Cancer Driver | No | 100 | 0.148 | 65 | 8 | 0.123 | 2 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0007229 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FERMT3 | FERMT3 | Q86UX7 | Fermitin family homolog 3 | chr11 | GO:0007229 | Not Cancer Driver | No | 99 | 0.148 | 108 | 14 | 0.13 | 0 |
| FGR_ENST00000374004 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0007229 | Not Cancer Driver | No | 85 | 0.161 | 52 | 8 | 0.154 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0007229 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
| FUT8_ENST00000394586 | FUT8 | Q9BYC5 | Alpha-(1,6)-fucosyltransferase | chr14 | GO:0007229 | Not Cancer Driver | No | 79 | 0.137 | 80 | 19 | 0.237 | 1 |
| FYB1_ENST00000515010 | FYB1 | O15117 | FYN-binding protein 1 | chr5 | GO:0007229 | Not Cancer Driver | No | 176 | 0.225 | 687 | 161 | 0.234 | 0 |
| FYB2 | FYB2 | Q5VWT5 | FYN-binding protein 2 | chr1 | GO:0007229 | Not Cancer Driver | No | 150 | 0.206 | 547 | 124 | 0.227 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0007229 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0007229 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | GO:0007229 | Not Cancer Driver | No | 12 | 0.073 | 24 | 2 | 0.083 | 0 |
| ITGA1 | ITGA1 | P56199 | Integrin alpha-1 | chr5 | GO:0007229 | Not Cancer Driver | No | 156 | 0.132 | 107 | 13 | 0.121 | 0 |
| ITGA10 | ITGA10 | O75578 | Integrin alpha-10 | chr1 | GO:0007229 | Not Cancer Driver | No | 176 | 0.151 | 193 | 20 | 0.104 | 0 |
| ITGA11 | ITGA11 | Q9UKX5 | Integrin alpha-11 | chr15 | GO:0007229 | Not Cancer Driver | No | 167 | 0.141 | 104 | 13 | 0.125 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0007229 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
| ITGA2B | ITGA2B | P08514 | Integrin alpha-IIb | chr17 | GO:0007229 | Not Cancer Driver | No | 133 | 0.128 | 188 | 31 | 0.165 | 34 |
| ITGA3 | ITGA3 | P26006 | Integrin alpha-3 | chr17 | GO:0007229 | Not Cancer Driver | No | 106 | 0.101 | 129 | 18 | 0.14 | 3 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | GO:0007229 | Not Cancer Driver | No | 254 | 0.246 | 97 | 27 | 0.278 | 0 |
| ITGA5 | ITGA5 | P08648 | Integrin alpha-5 | chr12 | GO:0007229 | Not Cancer Driver | No | 127 | 0.121 | 201 | 29 | 0.144 | 0 |
| ITGA6_ENST00000442250 | ITGA6 | P23229 | Integrin alpha-6 | chr2 | GO:0007229 | Not Cancer Driver | No | 130 | 0.115 | 226 | 29 | 0.128 | 0 |
| ITGA7_ENST00000555728 | ITGA7 | Q13683 | Integrin alpha-7 | chr12 | GO:0007229 | Not Cancer Driver | No | 205 | 0.174 | 283 | 48 | 0.17 | 0 |
| ITGA8 | ITGA8 | P53708 | Integrin alpha-8 | chr10 | GO:0007229 | Not Cancer Driver | No | 292 | 0.275 | 114 | 26 | 0.228 | 1 |
| ITGA9 | ITGA9 | Q13797 | Integrin alpha-9 | chr3 | GO:0007229 | Not Cancer Driver | No | 137 | 0.132 | 70 | 14 | 0.2 | 0 |
| ITGAD | ITGAD | Q13349 | Integrin alpha-D | chr16 | GO:0007229 | Not Cancer Driver | No | 236 | 0.203 | 124 | 21 | 0.169 | 0 |
| ITGAE | ITGAE | P38570 | Integrin alpha-E | chr17 | GO:0007229 | Not Cancer Driver | No | 165 | 0.14 | 185 | 28 | 0.151 | 0 |
| ITGAL | ITGAL | P20701 | Integrin alpha-L | chr16 | GO:0007229 | Not Cancer Driver | No | 196 | 0.168 | 144 | 25 | 0.174 | 0 |
| ITGAM_ENST00000287497 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0007229 | Not Cancer Driver | No | 191 | 0.166 | 133 | 12 | 0.09 | 0 |
| ITGAV | ITGAV | P06756 | Integrin alpha-V | chr2 | GO:0007229 | Census | Yes | 153 | 0.146 | 92 | 9 | 0.098 | 0 |
| ITGAX_ENST00000268296 | ITGAX | P20702 | Integrin alpha-X | chr16 | GO:0007229 | Not Cancer Driver | No | 245 | 0.211 | 82 | 15 | 0.183 | 0 |
| ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0007229 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0007229 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0007229 | Not Cancer Driver | No | 147 | 0.191 | 59 | 9 | 0.153 | 15 |
| ITGB3 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0007229 | Not Cancer Driver | No | 124 | 0.157 | 66 | 5 | 0.076 | 30 |
| ITGB4 | ITGB4 | P16144 | Integrin beta-4 | chr17 | GO:0007229 | Not Cancer Driver | No | 248 | 0.136 | 753 | 86 | 0.114 | 14 |
| ITGB5 | ITGB5 | P18084 | Integrin beta-5 | chr3 | GO:0007229 | Not Cancer Driver | No | 86 | 0.108 | 27 | 3 | 0.111 | 0 |
| ITGB6_ENST00000409872 | ITGB6 | P18564 | Integrin beta-6 | chr2 | GO:0007229 | Not Cancer Driver | No | 120 | 0.152 | 26 | 4 | 0.154 | 3 |
| ITGB7 | ITGB7 | P26010 | Integrin beta-7 | chr12 | GO:0007229 | Not Cancer Driver | No | 80 | 0.1 | 125 | 3 | 0.024 | 0 |
| ITGB8 | ITGB8 | P26012 | Integrin beta-8 | chr7 | GO:0007229 | Not Cancer Driver | No | 126 | 0.164 | 26 | 3 | 0.115 | 0 |
| ITGBL1 | ITGBL1 | O95965 | Integrin beta-like protein 1 | chr13 | GO:0007229 | Not Cancer Driver | No | 98 | 0.198 | 0 | 0 | 0.0 | 0 |
| LAMA3 | LAMA3 | Q16787 | Laminin subunit alpha-3 | chr18 | GO:0007229 | Not Cancer Driver | No | 478 | 0.143 | 743 | 98 | 0.132 | 0 |
| LAMA5 | LAMA5 | O15230 | Laminin subunit alpha-5 | chr20 | GO:0007229 | Not Cancer Driver | No | 431 | 0.117 | 701 | 90 | 0.128 | 0 |
| LAT_ENST00000360872 | LAT | O43561 | Linker for activation of T-cells family member 1 | chr16 | GO:0007229 | Not Cancer Driver | No | 37 | 0.141 | 213 | 29 | 0.136 | 0 |
| MADCAM1 | MADCAM1 | Q13477 | Mucosal addressin cell adhesion molecule 1 | chr19 | GO:0007229 | Not Cancer Driver | No | 39 | 0.102 | 240 | 33 | 0.138 | 0 |
| MPIG6B | MPIG6B | O95866 | Megakaryocyte and platelet inhibitory receptor G6b | chr6 | GO:0007229 | Not Cancer Driver | No | 37 | 0.154 | 61 | 7 | 0.115 | 0 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0007229 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
| NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:0007229 | Not Cancer Driver | No | 106 | 0.127 | 516 | 72 | 0.14 | 0 |
| NME2 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | GO:0007229 | Not Cancer Driver | No | 13 | 0.086 | 11 | 1 | 0.091 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0007229 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| PLEK | PLEK | P08567 | Pleckstrin | chr2 | GO:0007229 | Not Cancer Driver | No | 81 | 0.231 | 39 | 9 | 0.231 | 0 |
| PLPP3 | PLPP3 | O14495 | Phospholipid phosphatase 3 | chr1 | GO:0007229 | Not Cancer Driver | No | 48 | 0.154 | 10 | 1 | 0.1 | 0 |
| PRAM1 | PRAM1 | Q96QH2 | PML-RARA-regulated adapter molecule 1 | chr19 | GO:0007229 | Not Cancer Driver | No | 118 | 0.176 | 628 | 117 | 0.186 | 0 |
| PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0007229 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0007229 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0007229 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0007229 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0007229 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| PTPRA_ENST00000399903 | PTPRA | P18433 | Receptor-type tyrosine-protein phosphatase alpha | chr20 | GO:0007229 | Not Cancer Driver | No | 98 | 0.122 | 210 | 21 | 0.1 | 0 |
| RCC2 | RCC2 | Q9P258 | Protein RCC2 | chr1 | GO:0007229 | Not Cancer Driver | No | 63 | 0.121 | 194 | 27 | 0.139 | 0 |
| SEMA7A | SEMA7A | O75326 | Semaphorin-7A | chr15 | GO:0007229 | Not Cancer Driver | No | 81 | 0.122 | 150 | 21 | 0.14 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007229 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0007229 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TEC | TEC | P42680 | Tyrosine-protein kinase Tec | chr4 | GO:0007229 | Census, Compendium | Yes | 91 | 0.144 | 57 | 15 | 0.263 | 0 |
| THY1 | THY1 | P04216 | Thy-1 membrane glycoprotein | chr11 | GO:0007229 | Not Cancer Driver | No | 24 | 0.149 | 5 | 0 | 0.0 | 0 |
| TLN1 | TLN1 | Q9Y490 | Talin-1 | chr9 | GO:0007229 | Not Cancer Driver | No | 278 | 0.109 | 1109 | 126 | 0.114 | 0 |
| TSPAN32 | TSPAN32 | Q96QS1 | Tetraspanin-32 | chr11 | GO:0007229 | Not Cancer Driver | No | 33 | 0.103 | 8 | 3 | 0.375 | 0 |
| TXK | TXK | P42681 | Tyrosine-protein kinase TXK | chr4 | GO:0007229 | Not Cancer Driver | No | 87 | 0.165 | 61 | 9 | 0.148 | 0 |
| VAV1 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0007229 | Census, Compendium | Yes | 165 | 0.195 | 113 | 19 | 0.168 | 0 |
| VAV3 | VAV3 | Q9UKW4 | Guanine nucleotide exchange factor VAV3 | chr1 | GO:0007229 | Not Cancer Driver | No | 153 | 0.181 | 102 | 18 | 0.176 | 0 |
| ZNF304_ENST00000391705 | ZNF304 | Q9HCX3 | Zinc finger protein 304 | chr19 | GO:0007229 | Not Cancer Driver | No | 126 | 0.191 | 54 | 12 | 0.222 | 0 |
| ZYX | ZYX | Q15942 | Zyxin | chr7 | GO:0007229 | Not Cancer Driver | No | 83 | 0.145 | 385 | 52 | 0.135 | 0 |