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Total number of protein in "GO:0007189" GO term:  137

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0007189 Not Cancer Driver No 284 0.126 245 40 0.163 31
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0007189 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0007189 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0007189 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0007189 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0007189 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0007189 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0007189 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0007189 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 GO:0007189 Not Cancer Driver No 195 0.144 271 42 0.155 0
ADCYAP1_ENST00000450565 ADCYAP1 P18509 Pituitary adenylate cyclase-activating polypeptide chr18 GO:0007189 Not Cancer Driver No 43 0.244 75 11 0.147 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0007189 Compendium Yes 213 0.134 485 47 0.097 0
ADGRB2_ENST00000373658 ADGRB2 O60241 Adhesion G protein-coupled receptor B2 chr1 GO:0007189 Not Cancer Driver No 203 0.128 542 84 0.155 0
ADGRB3_ENST00000546190 ADGRB3 O60242 Adhesion G protein-coupled receptor B3 chr6 GO:0007189 Not Cancer Driver No 558 0.367 336 149 0.443 0
ADGRD1_ENST00000261654 ADGRD1 Q6QNK2 Adhesion G-protein coupled receptor D1 chr12 GO:0007189 Not Cancer Driver No 175 0.2 57 19 0.333 0
ADGRE1 ADGRE1 Q14246 Adhesion G protein-coupled receptor E1 chr19 GO:0007189 Not Cancer Driver No 204 0.23 15 7 0.467 0
ADGRE2 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0007189 Not Cancer Driver No 134 0.163 104 22 0.212 1
ADGRE3 ADGRE3 Q9BY15 Adhesion G protein-coupled receptor E3 chr19 GO:0007189 Not Cancer Driver No 116 0.178 82 11 0.134 0
ADGRE5 ADGRE5 P48960 Adhesion G protein-coupled receptor E5 chr19 GO:0007189 Not Cancer Driver No 115 0.138 109 10 0.092 0
ADGRF1 ADGRF1 Q5T601 Adhesion G-protein coupled receptor F1 chr6 GO:0007189 Not Cancer Driver No 159 0.175 8 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0007189 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRG2 ADGRG2 Q8IZP9 Adhesion G-protein coupled receptor G2 chrX GO:0007189 Not Cancer Driver No 151 0.148 309 44 0.142 0
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:0007189 Not Cancer Driver No 87 0.158 42 5 0.119 0
ADGRG4_ENST00000370652 ADGRG4 Q8IZF6 Adhesion G-protein coupled receptor G4 chrX GO:0007189 Not Cancer Driver No 715 0.232 1526 365 0.239 0
ADGRG5_ENST00000349457 ADGRG5 Q8IZF4 Adhesion G-protein coupled receptor G5 chr16 GO:0007189 Not Cancer Driver No 70 0.133 30 5 0.167 0
ADGRG6_ENST00000230173 ADGRG6 Q86SQ4 Adhesion G-protein coupled receptor G6 chr6 GO:0007189 Not Cancer Driver No 132 0.108 23 0 0.0 2
ADGRG7 ADGRG7 Q96K78 Adhesion G-protein coupled receptor G7 chr3 GO:0007189 Not Cancer Driver No 138 0.173 68 15 0.221 0
ADGRL1 ADGRL1 O94910 Adhesion G protein-coupled receptor L1 chr19 GO:0007189 Not Cancer Driver No 163 0.111 562 57 0.101 0
ADGRL2_ENST00000370728 ADGRL2 O95490 Adhesion G protein-coupled receptor L2 chr1 GO:0007189 Not Cancer Driver No 373 0.256 452 122 0.27 0
ADGRL3 ADGRL3 Q9HAR2 Adhesion G protein-coupled receptor L3 chr4 GO:0007189 Not Cancer Driver No 440 0.304 517 130 0.251 0
ADGRL4 ADGRL4 Q9HBW9 Adhesion G protein-coupled receptor L4 chr1 GO:0007189 Not Cancer Driver No 241 0.349 14 5 0.357 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0007189 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADM2_ENST00000395737 ADM2 Q7Z4H4 Protein ADM2 chr22 GO:0007189 Not Cancer Driver No 14 0.095 113 11 0.097 0
ADM5 ADM5 C9JUS6 Putative adrenomedullin-5-like protein chr19 GO:0007189 Not Cancer Driver No 6 0.039 35 4 0.114 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0007189 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0007189 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0007189 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA1B ADRA1B P35368 Alpha-1B adrenergic receptor chr5 GO:0007189 Not Cancer Driver No 53 0.102 132 1 0.008 0
ADRA1D ADRA1D P25100 Alpha-1D adrenergic receptor chr20 GO:0007189 Not Cancer Driver No 62 0.108 189 19 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0007189 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0007189 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0007189 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB1 ADRB1 P08588 Beta-1 adrenergic receptor chr10 GO:0007189 Not Cancer Driver No 35 0.073 116 1 0.009 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0007189 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADRB3 ADRB3 P13945 Beta-3 adrenergic receptor chr8 GO:0007189 Not Cancer Driver No 40 0.098 44 6 0.136 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0007189 Not Cancer Driver No 359 0.128 2091 258 0.123 0
CALCB CALCB P10092 Calcitonin gene-related peptide 2 chr11 GO:0007189 Not Cancer Driver No 23 0.181 52 8 0.154 0
CALCRL CALCRL Q16602 Calcitonin gene-related peptide type 1 receptor chr2 GO:0007189 Not Cancer Driver No 122 0.265 8 4 0.5 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0007189 Not Cancer Driver No 162 0.342 29 9 0.31 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0007189 Not Cancer Driver No 46 0.101 421 44 0.105 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0007189 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 GO:0007189 Not Cancer Driver No 57 0.158 21 4 0.19 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0007189 Not Cancer Driver No 75 0.169 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0007189 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0007189 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0007189 Not Cancer Driver No 32 0.256 38 16 0.421 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0007189 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0007189 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0007189 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0007189 Not Cancer Driver No 172 0.361 29 18 0.621 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0007189 Not Cancer Driver No 226 0.325 28 11 0.393 16
GALR1 GALR1 P47211 Galanin receptor type 1 chr18 GO:0007189 Not Cancer Driver No 68 0.195 32 2 0.062 0
GALR2 GALR2 O43603 Galanin receptor type 2 chr17 GO:0007189 Not Cancer Driver No 40 0.103 0 0 0.0 0
GCG GCG P01275 Pro-glucagon chr2 GO:0007189 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0007189 Not Cancer Driver No 16 0.034 56 2 0.036 4
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0007189 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0007189 Not Cancer Driver No 13 0.12 36 4 0.111 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0007189 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0007189 Not Cancer Driver No 45 0.097 41 0 0.0 0
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0007189 Not Cancer Driver No 75 0.162 18 2 0.111 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0007189 Compendium Yes 52 0.138 32 4 0.125 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0007189 Compendium Yes 50 0.141 24 0 0.0 0
GNAL_ENST00000269162 GNAL P38405 Guanine nucleotide-binding protein G(olf) subunit alpha chr18 GO:0007189 Not Cancer Driver No 56 0.147 46 4 0.087 2
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 GO:0007189 Census, Compendium Yes 57 0.159 14 1 0.071 1
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0007189 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0007189 Not Cancer Driver No 17 0.239 12 3 0.25 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0007189 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPHA2 GPHA2 Q96T91 Glycoprotein hormone alpha-2 chr11 GO:0007189 Not Cancer Driver No 15 0.116 0 0 0.0 0
GPHB5 GPHB5 Q86YW7 Glycoprotein hormone beta-5 chr14 GO:0007189 Not Cancer Driver No 32 0.246 0 0 0.0 0
GPR101 GPR101 Q96P66 Probable G-protein coupled receptor 101 chrX GO:0007189 Not Cancer Driver No 131 0.258 177 48 0.271 1
GPR119 GPR119 Q8TDV5 Glucose-dependent insulinotropic receptor chrX GO:0007189 Not Cancer Driver No 58 0.173 0 0 0.0 0
GPR12_ENST00000381436 GPR12 P47775 G-protein coupled receptor 12 chr13 GO:0007189 Not Cancer Driver No 69 0.207 0 0 0.0 0
GPR157 GPR157 Q5UAW9 G-protein coupled receptor 157 chr1 GO:0007189 Not Cancer Driver No 37 0.11 38 6 0.158 0
GPR161_ENST00000367835 GPR161 Q8N6U8 G-protein coupled receptor 161 chr1 GO:0007189 Not Cancer Driver No 84 0.159 108 16 0.148 0
GPR26 GPR26 Q8NDV2 G-protein coupled receptor 26 chr10 GO:0007189 Not Cancer Driver No 64 0.19 4 0 0.0 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:0007189 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0007189 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR62 GPR62 Q9BZJ7 G-protein coupled receptor 62 chr3 GO:0007189 Not Cancer Driver No 20 0.054 52 9 0.173 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0007189 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPR6_ENST00000275169 GPR6 P46095 G-protein coupled receptor 6 chr6 GO:0007189 Not Cancer Driver No 84 0.232 20 7 0.35 0
GPR78 GPR78 Q96P69 G-protein coupled receptor 78 chr4 GO:0007189 Not Cancer Driver No 80 0.22 45 9 0.2 0
HTR5A HTR5A P47898 5-hydroxytryptamine receptor 5A chr7 GO:0007189 Not Cancer Driver No 174 0.487 6 1 0.167 0
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0007189 Not Cancer Driver No 22 0.247 10 2 0.2 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0007189 Not Cancer Driver No 108 0.114 16 3 0.188 0
LGR5 LGR5 O75473 Leucine-rich repeat-containing G-protein coupled receptor 5 chr12 GO:0007189 Not Cancer Driver No 124 0.137 13 2 0.154 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0007189 Not Cancer Driver No 181 0.259 12 8 0.667 25
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0007189 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR2_ENST00000586703 LPAR2 Q9HBW0 Lysophosphatidic acid receptor 2 chr19 GO:0007189 Not Cancer Driver No 47 0.135 2 0 0.0 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0007189 Not Cancer Driver No 65 0.184 9 0 0.0 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0007189 Not Cancer Driver No 39 0.123 0 0 0.0 5
MC2R MC2R Q01718 Adrenocorticotropic hormone receptor chr18 GO:0007189 Not Cancer Driver No 65 0.219 0 0 0.0 9
MC3R MC3R P41968 Melanocortin receptor 3 chr20 GO:0007189 Not Cancer Driver No 96 0.297 0 0 0.0 0
MC4R MC4R P32245 Melanocortin receptor 4 chr18 GO:0007189 Not Cancer Driver No 57 0.172 2 0 0.0 29
MC5R_ENST00000324750 MC5R P33032 Melanocortin receptor 5 chr18 GO:0007189 Not Cancer Driver No 115 0.354 7 1 0.143 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0007189 Not Cancer Driver No 86 0.106 464 54 0.116 12
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0007189 Not Cancer Driver No 13 0.129 0 0 0.0 0
PLN PLN P26678 Cardiac phospholamban chr6 GO:0007189 Not Cancer Driver No 10 0.192 0 0 0.0 3
PTGER1 PTGER1 P34995 Prostaglandin E2 receptor EP1 subtype chr19 GO:0007189 Not Cancer Driver No 7 0.017 26 1 0.038 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0007189 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 GO:0007189 Not Cancer Driver No 79 0.203 17 2 0.118 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0007189 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0007189 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGIR PTGIR P43119 Prostacyclin receptor chr19 GO:0007189 Not Cancer Driver No 40 0.104 47 4 0.085 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0007189 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 GO:0007189 Not Cancer Driver No 86 0.145 124 25 0.202 5
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0007189 Not Cancer Driver No 44 0.249 132 40 0.303 2
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0007189 Not Cancer Driver No 16 0.108 0 0 0.0 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0007189 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0007189 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0007189 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF4 RAPGEF4 Q8WZA2 Rap guanine nucleotide exchange factor 4 chr2 GO:0007189 Not Cancer Driver No 149 0.147 191 29 0.152 0
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0007189 Not Cancer Driver No 74 0.341 29 11 0.379 0
RXFP1_ENST00000307765 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 GO:0007189 Not Cancer Driver No 152 0.201 0 0 0.0 0
RXFP2 RXFP2 Q8WXD0 Relaxin receptor 2 chr13 GO:0007189 Not Cancer Driver No 137 0.182 0 0 0.0 1
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0007189 Not Cancer Driver No 86 0.225 29 6 0.207 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0007189 Not Cancer Driver No 38 0.108 16 3 0.188 2
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0007189 Not Cancer Driver No 69 0.183 28 4 0.143 0
S1PR4 S1PR4 O95977 Sphingosine 1-phosphate receptor 4 chr19 GO:0007189 Not Cancer Driver No 68 0.177 11 2 0.182 0
S1PR5_ENST00000439028 S1PR5 Q9H228 Sphingosine 1-phosphate receptor 5 chr19 GO:0007189 Not Cancer Driver No 39 0.098 68 11 0.162 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0007189 Not Cancer Driver No 19 0.053 318 16 0.05 4
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0007189 Not Cancer Driver No 47 0.137 17 4 0.235 1
TCP11_ENST00000512012 TCP11 Q8WWU5 T-complex protein 11 homolog chr6 GO:0007189 Not Cancer Driver No 78 0.155 112 13 0.116 0
TMEM116_ENST00000550831 TMEM116 Q8NCL8 Transmembrane protein 116 chr12 GO:0007189 Not Cancer Driver No 23 0.094 4 0 0.0 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0007189 Census Yes 128 0.168 38 9 0.237 39
UCN2 UCN2 Q96RP3 Urocortin-2 chr3 GO:0007189 Not Cancer Driver No 10 0.089 48 4 0.083 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0007189 Not Cancer Driver No 22 0.137 74 11 0.149 0
VIP VIP P01282 VIP peptides chr6 GO:0007189 Not Cancer Driver No 58 0.341 77 25 0.325 0