Total number of protein in "GO:0007173" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0007173 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0007173 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0007173 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AREG | AREG | P15514 | Amphiregulin | chr4 | GO:0007173 | Not Cancer Driver | No | 28 | 0.111 | 149 | 20 | 0.134 | 0 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0007173 | Not Cancer Driver | No | 108 | 0.124 | 677 | 75 | 0.111 | 0 |
| BRAF | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | GO:0007173 | Census, Compendium | Yes | 791 | 1.033 | 310 | 43 | 0.139 | 39 |
| BTC | BTC | P35070 | Probetacellulin | chr4 | GO:0007173 | Not Cancer Driver | No | 29 | 0.163 | 12 | 5 | 0.417 | 0 |
| CAMLG | CAMLG | P49069 | Guided entry of tail-anchored proteins factor CAMLG | chr5 | GO:0007173 | Not Cancer Driver | No | 32 | 0.108 | 157 | 16 | 0.102 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0007173 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| DGKD | DGKD | Q16760 | Diacylglycerol kinase delta | chr2 | GO:0007173 | Not Cancer Driver | No | 160 | 0.132 | 441 | 60 | 0.136 | 0 |
| EFEMP1_ENST00000355426 | EFEMP1 | Q12805 | EGF-containing fibulin-like extracellular matrix protein 1 | chr2 | GO:0007173 | Not Cancer Driver | No | 95 | 0.193 | 73 | 21 | 0.288 | 1 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0007173 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0007173 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EPGN | EPGN | Q6UW88 | Epigen | chr4 | GO:0007173 | Not Cancer Driver | No | 16 | 0.104 | 0 | 0 | 0.0 | 0 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0007173 | Not Cancer Driver | No | 167 | 0.118 | 967 | 118 | 0.122 | 0 |
| EREG | EREG | O14944 | Proepiregulin | chr4 | GO:0007173 | Not Cancer Driver | No | 26 | 0.154 | 10 | 3 | 0.3 | 0 |
| FAM83A | FAM83A | Q86UY5 | Protein FAM83A | chr8 | GO:0007173 | Not Cancer Driver | No | 69 | 0.159 | 198 | 24 | 0.121 | 0 |
| FAM83B | FAM83B | Q5T0W9 | Protein FAM83B | chr6 | GO:0007173 | Not Cancer Driver | No | 314 | 0.311 | 684 | 219 | 0.32 | 0 |
| GAB1_ENST00000262994 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0007173 | Not Cancer Driver | No | 79 | 0.114 | 570 | 68 | 0.119 | 1 |
| GAREM1 | GAREM1 | Q9H706 | GRB2-associated and regulator of MAPK protein 1 | chr18 | GO:0007173 | Not Cancer Driver | No | 128 | 0.146 | 408 | 50 | 0.123 | 0 |
| GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0007173 | Not Cancer Driver | No | 28 | 0.129 | 10 | 1 | 0.1 | 0 |
| GRB7_ENST00000394209 | GRB7 | Q14451 | Growth factor receptor-bound protein 7 | chr17 | GO:0007173 | Not Cancer Driver | No | 84 | 0.158 | 134 | 27 | 0.201 | 0 |
| HBEGF | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0007173 | Not Cancer Driver | No | 16 | 0.077 | 63 | 3 | 0.048 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0007173 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| KIF16B_ENST00000354981 | KIF16B | Q96L93 | Kinesin-like protein KIF16B | chr20 | GO:0007173 | Not Cancer Driver | No | 248 | 0.188 | 436 | 74 | 0.17 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0007173 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0007173 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
| PIGR | PIGR | P01833 | Polymeric immunoglobulin receptor | chr1 | GO:0007173 | Not Cancer Driver | No | 126 | 0.165 | 177 | 37 | 0.209 | 0 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0007173 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0007173 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PLCE1 | PLCE1 | Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | chr10 | GO:0007173 | Not Cancer Driver | No | 367 | 0.159 | 780 | 107 | 0.137 | 1 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0007173 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0007173 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0007173 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0007173 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| RASSF2 | RASSF2 | P50749 | Ras association domain-containing protein 2 | chr20 | GO:0007173 | Not Cancer Driver | No | 90 | 0.276 | 126 | 44 | 0.349 | 0 |
| REPS2 | REPS2 | Q8NFH8 | RalBP1-associated Eps domain-containing protein 2 | chrX | GO:0007173 | Not Cancer Driver | No | 94 | 0.142 | 464 | 68 | 0.147 | 0 |
| RPS6KA5 | RPS6KA5 | O75582 | Ribosomal protein S6 kinase alpha-5 | chr14 | GO:0007173 | Not Cancer Driver | No | 97 | 0.121 | 187 | 18 | 0.096 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0007173 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SHC3 | SHC3 | Q92529 | SHC-transforming protein 3 | chr9 | GO:0007173 | Not Cancer Driver | No | 94 | 0.158 | 432 | 64 | 0.148 | 0 |
| SLC30A10 | SLC30A10 | Q6XR72 | Zinc transporter 10 | chr1 | GO:0007173 | Not Cancer Driver | No | 68 | 0.14 | 61 | 10 | 0.164 | 2 |
| SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0007173 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
| SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0007173 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0007173 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007173 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| TDGF1 | TDGF1 | P13385 | Teratocarcinoma-derived growth factor 1 | chr3 | GO:0007173 | Not Cancer Driver | No | 39 | 0.207 | 25 | 2 | 0.08 | 0 |
| TGFA_ENST00000295400 | TGFA | P01135 | Protransforming growth factor alpha | chr2 | GO:0007173 | Not Cancer Driver | No | 20 | 0.125 | 0 | 0 | 0.0 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0007173 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0007173 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |