Total number of protein in "GO:0007059" GO term: 80
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABRAXAS2 | ABRAXAS2 | Q15018 | BRISC complex subunit Abraxas 2 | chr10 | GO:0007059 | Not Cancer Driver | No | 47 | 0.113 | 207 | 26 | 0.126 | 0 |
| ARL8A | ARL8A | Q96BM9 | ADP-ribosylation factor-like protein 8A | chr1 | GO:0007059 | Not Cancer Driver | No | 23 | 0.124 | 0 | 0 | 0.0 | 0 |
| ARL8B | ARL8B | Q9NVJ2 | ADP-ribosylation factor-like protein 8B | chr3 | GO:0007059 | Not Cancer Driver | No | 28 | 0.151 | 0 | 0 | 0.0 | 0 |
| BANF1_ENST00000445560 | BANF1 | O75531 | Barrier-to-autointegration factor | chr11 | GO:0007059 | Not Cancer Driver | No | 10 | 0.112 | 11 | 2 | 0.182 | 1 |
| BANF2_ENST00000377805 | BANF2 | Q9H503 | Barrier-to-autointegration factor-like protein | chr20 | GO:0007059 | Not Cancer Driver | No | 11 | 0.122 | 0 | 0 | 0.0 | 0 |
| BEX4_ENST00000372691 | BEX4 | Q9NWD9 | Protein BEX4 | chrX | GO:0007059 | Not Cancer Driver | No | 13 | 0.108 | 120 | 13 | 0.108 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0007059 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
| CDCA2 | CDCA2 | Q69YH5 | Cell division cycle-associated protein 2 | chr8 | GO:0007059 | Not Cancer Driver | No | 124 | 0.121 | 828 | 100 | 0.121 | 0 |
| CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0007059 | Not Cancer Driver | No | 217 | 0.115 | 1136 | 128 | 0.113 | 0 |
| CDT1 | CDT1 | Q9H211 | DNA replication factor Cdt1 | chr16 | GO:0007059 | Not Cancer Driver | No | 60 | 0.11 | 377 | 35 | 0.093 | 5 |
| CENPC | CENPC | Q03188 | Centromere protein C | chr4 | GO:0007059 | Not Cancer Driver | No | 96 | 0.102 | 790 | 84 | 0.106 | 0 |
| CENPE | CENPE | Q02224 | Centromere-associated protein E | chr4 | GO:0007059 | Not Cancer Driver | No | 343 | 0.127 | 1620 | 228 | 0.141 | 2 |
| CENPF | CENPF | P49454 | Centromere protein F | chr1 | GO:0007059 | Not Cancer Driver | No | 387 | 0.124 | 2136 | 260 | 0.122 | 0 |
| CENPH | CENPH | Q9H3R5 | Centromere protein H | chr5 | GO:0007059 | Not Cancer Driver | No | 28 | 0.113 | 85 | 7 | 0.082 | 0 |
| CENPN_ENST00000305850 | CENPN | Q96H22 | Centromere protein N | chr16 | GO:0007059 | Not Cancer Driver | No | 47 | 0.139 | 22 | 5 | 0.227 | 0 |
| CENPT_ENST00000440851 | CENPT | Q96BT3 | Centromere protein T | chr16 | GO:0007059 | Not Cancer Driver | No | 59 | 0.105 | 468 | 55 | 0.118 | 0 |
| CENPW_ENST00000368328 | CENPW | Q5EE01 | Centromere protein W | chr6 | GO:0007059 | Not Cancer Driver | No | 9 | 0.102 | 5 | 1 | 0.2 | 0 |
| CEP85 | CEP85 | Q6P2H3 | Centrosomal protein of 85 kDa | chr1 | GO:0007059 | Not Cancer Driver | No | 77 | 0.101 | 607 | 60 | 0.099 | 0 |
| CIAO1 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | GO:0007059 | Not Cancer Driver | No | 30 | 0.088 | 20 | 2 | 0.1 | 0 |
| CIAO2A | CIAO2A | Q9H5X1 | Cytosolic iron-sulfur assembly component 2A | chr15 | GO:0007059 | Not Cancer Driver | No | 24 | 0.15 | 28 | 4 | 0.143 | 0 |
| CIAO2B | CIAO2B | Q9Y3D0 | Cytosolic iron-sulfur assembly component 2B | chr16 | GO:0007059 | Not Cancer Driver | No | 9 | 0.055 | 77 | 3 | 0.039 | 0 |
| CTCF | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | GO:0007059 | Census, Compendium | Yes | 151 | 0.208 | 481 | 83 | 0.173 | 1 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0007059 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DLGAP5 | DLGAP5 | Q15398 | Disks large-associated protein 5 | chr14 | GO:0007059 | Not Cancer Driver | No | 84 | 0.099 | 676 | 70 | 0.104 | 0 |
| ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0007059 | Census, Compendium | Yes | 150 | 0.197 | 5 | 0 | 0.0 | 35 |
| HJURP | HJURP | Q8NCD3 | Holliday junction recognition protein | chr2 | GO:0007059 | Not Cancer Driver | No | 108 | 0.144 | 572 | 85 | 0.149 | 0 |
| INCENP | INCENP | Q9NQS7 | Inner centromere protein | chr11 | GO:0007059 | Not Cancer Driver | No | 107 | 0.117 | 856 | 103 | 0.12 | 0 |
| KNSTRN | KNSTRN | Q9Y448 | Small kinetochore-associated protein | chr15 | GO:0007059 | Census | Yes | 75 | 0.237 | 246 | 67 | 0.272 | 0 |
| M1AP | M1AP | Q8TC57 | Meiosis 1 arrest protein | chr2 | GO:0007059 | Not Cancer Driver | No | 81 | 0.153 | 157 | 27 | 0.172 | 0 |
| MEIKIN | MEIKIN | A0A087WXM9 | Meiosis-specific kinetochore protein | chr5 | GO:0007059 | Not Cancer Driver | No | 2 | 0.005 | 221 | 1 | 0.005 | 0 |
| MIS12 | MIS12 | Q9H081 | Protein MIS12 homolog | chr17 | GO:0007059 | Not Cancer Driver | No | 14 | 0.068 | 15 | 2 | 0.133 | 0 |
| MIS18A | MIS18A | Q9NYP9 | Protein Mis18-alpha | chr21 | GO:0007059 | Not Cancer Driver | No | 20 | 0.086 | 15 | 1 | 0.067 | 0 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0007059 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:0007059 | Not Cancer Driver | No | 73 | 0.071 | 11 | 0 | 0.0 | 0 |
| NAA60_ENST00000572584 | NAA60 | Q9H7X0 | N-alpha-acetyltransferase 60 | chr16 | GO:0007059 | Not Cancer Driver | No | 33 | 0.136 | 0 | 0 | 0.0 | 0 |
| NCAPH | NCAPH | Q15003 | Condensin complex subunit 2 | chr2 | GO:0007059 | Not Cancer Driver | No | 97 | 0.131 | 465 | 60 | 0.129 | 1 |
| NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | GO:0007059 | Not Cancer Driver | No | 67 | 0.111 | 335 | 39 | 0.116 | 0 |
| NDC80 | NDC80 | O14777 | Kinetochore protein NDC80 homolog | chr18 | GO:0007059 | Not Cancer Driver | No | 80 | 0.125 | 313 | 45 | 0.144 | 0 |
| NDE1_ENST00000396354 | NDE1 | Q9NXR1 | Nuclear distribution protein nudE homolog 1 | chr16 | GO:0007059 | Not Cancer Driver | No | 45 | 0.134 | 316 | 42 | 0.133 | 0 |
| NDEL1 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | GO:0007059 | Not Cancer Driver | No | 32 | 0.093 | 202 | 16 | 0.079 | 0 |
| NEK11 | NEK11 | Q8NG66 | Serine/threonine-protein kinase Nek11 | chr3 | GO:0007059 | Not Cancer Driver | No | 91 | 0.141 | 264 | 45 | 0.17 | 0 |
| NEK2 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | GO:0007059 | Not Cancer Driver | No | 61 | 0.137 | 92 | 19 | 0.207 | 0 |
| NEK6_ENST00000545174 | NEK6 | Q9HC98 | Serine/threonine-protein kinase Nek6 | chr9 | GO:0007059 | Not Cancer Driver | No | 31 | 0.099 | 36 | 0 | 0.0 | 0 |
| NEK8 | NEK8 | Q86SG6 | Serine/threonine-protein kinase Nek8 | chr17 | GO:0007059 | Not Cancer Driver | No | 102 | 0.147 | 167 | 40 | 0.24 | 3 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0007059 | Not Cancer Driver | No | 92 | 0.118 | 362 | 37 | 0.102 | 12 |
| NTMT1_ENST00000613644 | NTMT1 | Q9BV86 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | chr9 | GO:0007059 | Not Cancer Driver | No | 27 | 0.121 | 1 | 0 | 0.0 | 0 |
| NUF2_ENST00000367900 | NUF2 | Q9BZD4 | Kinetochore protein Nuf2 | chr1 | GO:0007059 | Not Cancer Driver | No | 97 | 0.209 | 74 | 20 | 0.27 | 0 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | GO:0007059 | Census, Compendium | Yes | 234 | 0.111 | 1864 | 203 | 0.109 | 0 |
| NUP37_ENST00000251074 | NUP37 | Q8NFH4 | Nucleoporin Nup37 | chr12 | GO:0007059 | Not Cancer Driver | No | 39 | 0.12 | 0 | 0 | 0.0 | 0 |
| NUP43 | NUP43 | Q8NFH3 | Nucleoporin Nup43 | chr6 | GO:0007059 | Not Cancer Driver | No | 47 | 0.124 | 103 | 9 | 0.087 | 0 |
| OIP5 | OIP5 | O43482 | Protein Mis18-beta | chr15 | GO:0007059 | Not Cancer Driver | No | 31 | 0.135 | 65 | 7 | 0.108 | 0 |
| PHF13 | PHF13 | Q86YI8 | PHD finger protein 13 | chr1 | GO:0007059 | Not Cancer Driver | No | 52 | 0.173 | 158 | 25 | 0.158 | 0 |
| PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0007059 | Not Cancer Driver | No | 87 | 0.144 | 119 | 13 | 0.109 | 0 |
| PMF1_ENST00000368277 | PMF1 | Q6P1K2 | Polyamine-modulated factor 1 | chr1 | GO:0007059 | Not Cancer Driver | No | 20 | 0.098 | 76 | 6 | 0.079 | 0 |
| PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | GO:0007059 | Census, Compendium | Yes | 179 | 0.304 | 0 | 0 | 0.0 | 4 |
| RCC1_ENST00000373833 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | GO:0007059 | Not Cancer Driver | No | 54 | 0.128 | 143 | 15 | 0.105 | 0 |
| RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0007059 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
| RIOK3 | RIOK3 | O14730 | Serine/threonine-protein kinase RIO3 | chr18 | GO:0007059 | Not Cancer Driver | No | 58 | 0.112 | 225 | 21 | 0.093 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0007059 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SETDB2 | SETDB2 | Q96T68 | Histone-lysine N-methyltransferase SETDB2 | chr13 | GO:0007059 | Not Cancer Driver | No | 70 | 0.097 | 253 | 26 | 0.103 | 0 |
| SGO1 | SGO1 | Q5FBB7 | Shugoshin 1 | chr3 | GO:0007059 | Not Cancer Driver | No | 57 | 0.102 | 360 | 39 | 0.108 | 1 |
| SKA1_ENST00000398452 | SKA1 | Q96BD8 | Spindle and kinetochore-associated protein 1 | chr18 | GO:0007059 | Not Cancer Driver | No | 23 | 0.09 | 74 | 7 | 0.095 | 0 |
| SKA2 | SKA2 | Q8WVK7 | Spindle and kinetochore-associated protein 2 | chr17 | GO:0007059 | Not Cancer Driver | No | 12 | 0.099 | 44 | 6 | 0.136 | 0 |
| SKA3 | SKA3 | Q8IX90 | Spindle and kinetochore-associated protein 3 | chr13 | GO:0007059 | Not Cancer Driver | No | 56 | 0.136 | 230 | 32 | 0.139 | 0 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | GO:0007059 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SPAG5 | SPAG5 | Q96R06 | Sperm-associated antigen 5 | chr17 | GO:0007059 | Not Cancer Driver | No | 136 | 0.114 | 636 | 83 | 0.131 | 0 |
| SPC24 | SPC24 | Q8NBT2 | Kinetochore protein Spc24 | chr19 | GO:0007059 | Not Cancer Driver | No | 9 | 0.046 | 88 | 5 | 0.057 | 0 |
| SPC25 | SPC25 | Q9HBM1 | Kinetochore protein Spc25 | chr2 | GO:0007059 | Not Cancer Driver | No | 15 | 0.067 | 34 | 2 | 0.059 | 0 |
| SRPK1 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | GO:0007059 | Not Cancer Driver | No | 73 | 0.111 | 329 | 32 | 0.097 | 0 |
| TEX11_ENST00000344304 | TEX11 | Q8IYF3 | Testis-expressed protein 11 | chrX | GO:0007059 | Not Cancer Driver | No | 139 | 0.148 | 30 | 3 | 0.1 | 2 |
| TLK1 | TLK1 | Q9UKI8 | Serine/threonine-protein kinase tousled-like 1 | chr2 | GO:0007059 | Not Cancer Driver | No | 103 | 0.134 | 388 | 53 | 0.137 | 0 |
| TLK2 | TLK2 | Q86UE8 | Serine/threonine-protein kinase tousled-like 2 | chr17 | GO:0007059 | Not Cancer Driver | No | 120 | 0.155 | 436 | 58 | 0.133 | 5 |
| TOP1 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | GO:0007059 | Census, Compendium | Yes | 93 | 0.122 | 391 | 53 | 0.136 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0007059 | Compendium | Yes | 150 | 0.098 | 508 | 59 | 0.116 | 0 |
| TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | GO:0007059 | Not Cancer Driver | No | 102 | 0.118 | 151 | 17 | 0.113 | 0 |
| TTK | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | GO:0007059 | Not Cancer Driver | No | 136 | 0.159 | 352 | 46 | 0.131 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | GO:0007059 | Not Cancer Driver | No | 16 | 0.101 | 16 | 3 | 0.188 | 0 |
| USP44_ENST00000537435 | USP44 | Q9H0E7 | Ubiquitin carboxyl-terminal hydrolase 44 | chr12 | GO:0007059 | Census, Compendium | Yes | 94 | 0.132 | 114 | 14 | 0.123 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0007059 | Census, Compendium | Yes | 339 | 0.133 | 405 | 51 | 0.126 | 1 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0007059 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |